Policy Notices

• Upcoming Changes to the Biographical Sketch and Other Support Format Page for Due Dates on or after May 25, 2021
  (NOT-OD-21-073)
  National Institutes of Health
  

General Notices

• Request for Information (RFI): Invitation to Comment on the Draft NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Down Syndrome Research Plan
  (NOT-HD-21-014)
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  Office of the Director, NIH
  

• Request for Information (RFI): Improving the Mental Health of Rural People
  (NOT-MH-21-190)
  National Institute of Mental Health
  

Notice of Changes to Funding Opportunities

• Notice of NIAMS Participation in NOT-EB-21-001 "Notice of Special Interest (NOSI): Small Business Initiatives for Innovative Diagnostic Technology for Improving Outcomes for Maternal Health"
  (NOT-AR-21-019)
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  

• Notice of Change to update the FOA title for RFA-FD-21-029 "Alliance to Support Integrated Public Health System Activities (U2F) Clinical Trials Not Allowed"
  (NOT-FD-21-012)
  Food and Drug Administration
  

• Notice of Early Expiration of NOT-MH-21-075 Notice of Special Interest (NOSI) regarding the Use of Human Connectome Data for Secondary Analysis
  (NOT-MH-21-210)
  National Institute of Mental Health
  

• Notice of NINR Participation in PA-18-935, "Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement/Clinical Trial Optional)"
  (NOT-NR-21-002)
  National Institute of Nursing Research
  

• Notice of Correction to Application Types Allowed for RFA-TR-21-010 Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases (U44 Clinical Trial Required)
  (NOT-TR-21-023)
  National Center for Advancing Translational Sciences
  

Notices of Special Interest

• Notice of Special Interest (NOSI): Administrative Supplements to SEPA Awards to Develop Innovative Educational Resources to Address SARS-CoV-2 Vaccine Hesitancy
  (NOT-GM-21-032)
  National Institute of General Medical Sciences
  

• Notice of Special Interest (NOSI): Understanding and Addressing the Impact of Structural Racism and Discrimination on Biomedical Career Progression and the Biomedical Research Enterprise
  (NOT-GM-21-033)
  National Institute of General Medical Sciences
  

• Notice of Special Interest (NOSI): Using Systems Science Methodologies to Protect and Improve Child and Reproductive Population Health
  (NOT-HD-20-032)
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Cancer Institute
  Office of Disease Prevention
  

• Notice of Special Interest (NOSI): NINR Priority Areas for Training and Career Development Awards
  (NOT-NR-21-001)
  National Institute of Nursing Research
  

• Notice of Special Interest: Innovative Approaches or Technologies to Investigate Regional, Structural and Functional Heterogeneity of CNS Small Blood and Lymphatic Vessels in AD/ADRD
  (NOT-NS-21-039)
  National Institute of Neurological Disorders and Stroke
  

Funding Opportunities

• AHRQ/PCORI Learning Health System Small Grant Pilot Program
  (PA-21-202)
  Agency for Healthcare Research and Quality
  Application Receipt Date(s): June 19, 2023
  
  

• Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)
  (PAR-21-122)
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
  (PAR-21-123)
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)
  (PAR-21-124)
  National Institute of Neurological Disorders and Stroke
  National Center for Complementary and Integrative Health
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
  (PAR-21-163)
  National Institute of Neurological Disorders and Stroke
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Biomedical Imaging and Bioengineering
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute of Dental and Craniofacial Research
  National Institute of Mental Health
  Office of Behavioral and Social Sciences Research
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
  (PAR-21-190)
  National Cancer Institute
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• New Directions in Hematology Research (SHINE-II) (R01 Clinical Trial Optional)
  (PAS-21-150)
  National Institute of Diabetes and Digestive and Kidney Diseases
  National Heart, Lung, and Blood Institute
  National Institute on Aging
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Expanding the opioids system modeling efforts to more comprehensively address fentanyl, stimulants use, polysubstance use and associated outcomes. (U01) Clinical Trials Not Allowed
  (RFA-FD-21-022)
  Food and Drug Administration
  Application Receipt Date(s): May 17, 2021, by 11:59 PM Eastern Time. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date. Applicants should be aware that on-time submission means that an application is submitted error free (of both Grants.gov and eRA Commons errors) by 11:59 PM Eastern Time on the application due date. Late applications will not be accepted for this FOA.
  
  

• Enhancing Innovations in Advanced Manufacturing Technologies for Vaccines against Influenza and Emerging Infectious Diseases (R01) Clinical Trials Not Allowed
  (RFA-FD-21-033)
  Food and Drug Administration
  Application Receipt Date(s): May 18, 2021, by 11:59 PM Eastern Time. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date. Applicants should be aware that on-time submission means that an application is submitted error free (of both Grants.gov and eRA Commons errors) by 11:59 PM Eastern Time on the application due date. Late applications will not be accepted for this FOA.
  
  

• Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)
  (RFA-MD-21-005)
  National Institute on Minority Health and Health Disparities
  Application Receipt Date(s): May 3, 2021 No late applications will be accepted for this Funding Opportunity Announcement.
  
  

• Innovations for Healthy Living - Improving Minority Health and Eliminating Health Disparities (R43/R44 - Clinical Trial Optional)
  (RFA-MD-21-006)
  National Institute on Minority Health and Health Disparities
  Application Receipt Date(s): May 3, 2021 No late applications will be accepted for this Funding Opportunity Announcement.
  
  

• BRAIN Initiative: Secondary Analysis and Archiving of BRAIN Initiative Data (R01 Clinical Trial Not Allowed)
  (RFA-MH-21-130)
  National Institute of Mental Health
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Biomedical Imaging and Bioengineering
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute on Deafness and Other Communication Disorders
  National Institute of Neurological Disorders and Stroke
  Office of Behavioral and Social Sciences Research
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• BRAIN Initiative: Integration and Analysis of BRAIN Initiative Data (R01 Clinical Trial Not Allowed)
  (RFA-MH-21-135)
  National Institute of Mental Health
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Biomedical Imaging and Bioengineering
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute on Deafness and Other Communication Disorders
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Limited Competition to Convert the CNS HIV Antiretroviral Therapy Effects Research (CHARTER) Study Cohort to a Research Resource (R24 - Clinical Trial Not Allowed)
  (RFA-MH-21-170)
  National Institute of Mental Health
  National Institute on Aging
  National Institute on Drug Abuse
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): May 10, 2021
  
  

• HEAL Initiative: Analgesic Development Initial Translational Efforts [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed)
  (RFA-NS-21-015)
  National Institute of Neurological Disorders and Stroke
  National Center for Advancing Translational Sciences
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute of Dental and Craniofacial Research
  National Institute of Mental Health
  Application Receipt Date(s): April 27, 2021, June 22, 2021, October 13, 2021, June 9, 2022, October 11, 2022, June 9, 2023, and October 10, 2023 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
  
  

• HEAL Initiative: Planning Studies for Initial Analgesic Development Initial Translational Efforts [Small Molecules and Biologics] (R34 Clinical Trial Not Allowed)
  (RFA-NS-21-016)
  National Institute of Neurological Disorders and Stroke
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute of Dental and Craniofacial Research
  National Institute of Mental Health
  Application Receipt Date(s): April 27, 2021
  
  

• Secondary Analyses of Existing Datasets of Tobacco Use and Health (R21 Clinical Trial Not Allowed)
  (RFA-OD-21-003)
  National Institutes of Health
  National Cancer Institute
  National Heart, Lung, and Blood Institute
  National Institute on Alcohol Abuse and Alcoholism
  National Institute on Drug Abuse
  National Institute of Environmental Health Sciences
  Application Receipt Date(s): October 8, 2021, August 8, 2022, March 8, 2023
  
  

• Maximizing the Scientific Value of Existing Biospecimen Collections (R21 Clinical Trial Not Allowed)
  (RFA-OD-21-004)
  National Institutes of Health
  National Cancer Institute
  National Heart, Lung, and Blood Institute
  National Institute on Alcohol Abuse and Alcoholism
  National Institute on Drug Abuse
  National Institute of Environmental Health Sciences
  National Institutes of Health
  Application Receipt Date(s): October 8, 2021, August 8, 2022, March 8, 2023