Policy Notices

• AHRQ Announces Interest in Research on Climate Change and Healthcare
  (NOT-HS-23-006)
  Agency for Healthcare Research and Quality
  

• Notice of Intent to Publish Funding Opportunity Announcement to Support the Management of Substance Use Disorders in Primary Care and other Ambulatory Settings (R18)
  (NOT-HS-23-007)
  Agency for Healthcare Research and Quality
  

• Guidance on Salary Limitation for Grants and Cooperative Agreements FY 2023
  (NOT-OD-23-056)
  National Institutes of Health
  

General Notices

• Notice of Guidance for Data Management and Sharing Plans for the National Institute of Alcohol Abuse and Alcoholism (NIAAA)
  (NOT-AA-23-001)
  National Institute on Alcohol Abuse and Alcoholism
  

• Notice of NIAAA Data-Sharing Information for Human Subjects Grants Research Funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) [5th Revision]
  (NOT-AA-23-002)
  National Institute on Alcohol Abuse and Alcoholism
  

• Notice of Pre-Application Webinar for RFA-DK-22-012 NIDDK Investigator Award to Support Mentoring of Early Career Researchers from Diverse Backgrounds (K26 - Independent Clinical Trial Not Allowed)
  (NOT-DK-23-008)
  National Institute of Diabetes and Digestive and Kidney Diseases
  

• Notice of NIBIB Specific Interests and Guidance in RFA-NS-23-006 HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
  (NOT-EB-22-012)
  National Institute of Biomedical Imaging and Bioengineering
  

• Notice of Modification to Require All NINDS-Funded TBI Human Subjects Research Data to Submit to the Federal Interagency Traumatic Brain Injury Research (FITBIR) Informatics System
  (NOT-NS-23-046)
  National Institute of Neurological Disorders and Stroke
  

• Technical Assistance Webinar for PAR-23-066: Research on Community Level Interventions for Firearm and Related Violence Injury and Mortality Prevention (CLIF-VP)
  (NOT-OD-23-059)
  Office of Behavioral and Social Sciences Research
  

• Notice of Information to Expire the PAR-21-311, Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional)
  (NOT-TW-23-001)
  John E. Fogarty International Center
  

• Notice of Information to Expire PAR-21-319, Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trials Optional)
  (NOT-TW-23-002)
  John E. Fogarty International Center
  

• Request for Information (RFI): Cancer Therapeutic Clinical Trials in Low- and Middle-Income Countries
  (NOT-CA-23-015)
  National Cancer Institute
  

Notice of Changes to Funding Opportunities

• Notice to Extend the Expiration Date of PAR-20-156 "Translational Bioinformatics Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease (R01 Clinical Trial Optional)"
  (NOT-AG-22-051)
  National Institute on Aging
  

• Notice of Early Expiration and Reissue of RFA-DA-22-038, "Accelerating the Pace of Drug Abuse Research Using Existing Data (R21 Clinical Trial Optional)"
  (NOT-DA-23-015)
  National Institute on Drug Abuse
  

• Notice of Change in Application Due Date for RFA-EB-21-001
  (NOT-EB-22-016)
  National Institute of Biomedical Imaging and Bioengineering
  National Institute on Minority Health and Health Disparities
  

• Notice of Change to Eligibility information for RFA-NS-23-003 "HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)"
  (NOT-NS-23-057)
  National Institute of Neurological Disorders and Stroke
  

• Notice of Change to RFA-PM-23-001, Enhancing the Use of the All of Us Research Programs Data (R21 Clinical Trial Not Allowed);
  (NOT-PM-23-004)
  Office of the Director, NIH
  

• Notice of Change to RFA-PM-23-002, Small Grants to Enhance the Use of the All of Us Research Programs Data (R03 Clinical Trial Not Allowed)
  (NOT-PM-23-005)
  Office of the Director, NIH
  

• Notice of Clarification to RFA-TR-22-030 "Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)"
  (NOT-TR-23-004)
  National Center for Advancing Translational Sciences
  

Notices of Intent to Publish

• Notice of Intent to Publish a Funding Opportunity Announcement for Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional)
  (NOT-DA-23-014)
  National Institute on Drug Abuse
  

Requests for Proposal

• Notice of Request for Proposals (RFP), Solicitation 75N91023R00024: PREVENT Cancer Preclinical Drug Development Program
  (NOT-CA-23-034)
  National Cancer Institute
  

Notices of Special Interest

• Notice of Special Interest (NOSI): Adaptive Biomaterials for Cancer Biology
  (NOT-CA-23-030)
  National Cancer Institute
  

• Notice of Special Interest (NOSI): Administrative Supplement to Support Global Cancer Stigma Research
  (NOT-CA-23-036)
  National Cancer Institute
  

• Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases
  (NOT-DA-22-048)
  National Institute on Drug Abuse
  National Cancer Institute
  National Institute of Dental and Craniofacial Research
  

• Notice of Special Interest (NOSI): Administrative Supplements to Support Programs for Inclusion and Diversity Among Individuals Engaged in Health-Related Research (PRIDE) Small Research Projects (SRPs)
  (NOT-HL-22-039)
  National Heart, Lung, and Blood Institute
  

Funding Opportunities

• Archiving and Documenting Child Health and Human Development Data Sets (R03 Clinical Trial Not Allowed)
  (PAR-22-261)
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Formative and Pilot Intervention Research to Optimize HIV Prevention and Care Continuum Outcomes (R34 Clinical Trial Optional)
  (PAR-23-060)
  National Institute of Mental Health
  Application Receipt Date(s): January 09, 2026
  
  

• Innovations to Optimize HIV Prevention and Care Continuum Outcomes (R21 Clinical Trial Optional)
  (PAR-23-061)
  National Institute of Mental Health
  Application Receipt Date(s): January 09, 2026
  
  

• Innovations to Optimize HIV Prevention and Care Continuum Outcomes (R01 Clinical Trial Optional)
  (PAR-23-062)
  National Institute of Mental Health
  Application Receipt Date(s): January 09, 2026
  
  

• NIDA Program Project Grant Applications (P01 Clinical Trial Optional)
  (PAR-23-064)
  National Institute on Drug Abuse
  Application Receipt Date(s): January 07, 2026
  
  

• NIAID Physician-Scientist Pathway to Independence Award (K99/R00 Clinical Trial Required)
  (PAR-23-070)
  National Institute of Allergy and Infectious Diseases
  Application Receipt Date(s): Standard dates apply. The first standard due date for this FOA is February 12, 2023. All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applications are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
  
  

• NIAID Physician-Scientist Pathway to Independence Award (K99/R00 Independent Clinical Trial Not Allowed)
  (PAR-23-071)
  National Institute of Allergy and Infectious Diseases
  Application Receipt Date(s): Standard dates apply. The first standard due date for this FOA is, February 12, 2023 All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applications are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
  
  

• Mentored Career Development Program for Early Stage Investigators Using Nonhuman Primate Research Models (K01 Independent Clinical Trial Not Allowed)
  (PAR-23-073)
  National Institute of Allergy and Infectious Diseases
  National Institute on Aging
  Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs
  Application Receipt Date(s): January 07, 2026
  
  

• In-Depth Phenotyping and Research Using IMPC-Generated Knockout Mouse Strains Exhibiting Embryonic or Perinatal Lethality or Subviability (R01 Clinical Trial Not Allowed)
  (PAR-23-074)
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute of Dental and Craniofacial Research
  Office of Research on Women's Health
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• NIDA Research Center of Excellence Grant Program (P50 Clinical Trial Optional)
  (PAR-23-076)
  National Institute on Drug Abuse
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Integrative Research to Understand the Impact of Sex Differences on the Molecular Determinants of AD Risk and Responsiveness to Treatment (U01 Clinical Trial Optional)
  (PAR-23-082)
  National Institute on Aging
  Application Receipt Date(s): February 21, 2025
  
  

• Investigator Initiated Extended Clinical Trial (R01 Clinical Trial Required)
  (PAR-23-084)
  National Institute of Allergy and Infectious Diseases
  National Institute on Aging
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Novel Assays to Address Translational Gaps in Treatment Development (UG3/UH3 Clinical Trial Optional)
  (PAR-23-087)
  National Institute of Mental Health
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
  (PAR-23-101)
  National Institute of Mental Health
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)
  (PAR-23-102)
  National Institute of Mental Health
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Implementing and Sustaining Evidence-Based Mental Health Practices in Low-Resource Settings to Achieve Equity in Outcomes (R34 Clinical Trial Required )
  (PAR-23-103)
  National Institute of Mental Health
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Pilot Studies to Test the Initiation of a Mental Health Family Navigator Model to Promote Early Access, Engagement and Coordination of Needed Mental Health Services for Children and Adolescents (R34 Clinical Trial Required)
  (PAR-23-104)
  National Institute of Mental Health
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
  (PAR-23-105)
  National Institute of Mental Health
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Alzheimer's Disease Research Centers (P30 Clinical Trial Not Allowed)
  (RFA-AG-24-001)
  National Institute on Aging
  Application Receipt Date(s): September 26, 2025
  
  

• Renewal of the Interventions Testing Program (U01 Clinical Trial Not Allowed)
  (RFA-AG-24-002)
  National Institute on Aging
  Application Receipt Date(s): June 19, 2023
  
  

• Interventions Testing Program (ITP) Data Coordinating Center (U24 Clinical Trial Not Allowed)
  (RFA-AG-24-003)
  National Institute on Aging
  Application Receipt Date(s): June 19, 2023
  
  

• Planning for the TMD Collaborative for IMproving PAtient-Centered Translational Research (TMD IMPACT) (R34 Clinical Trial Not Allowed)
  (RFA-DE-23-014)
  National Institute of Dental and Craniofacial Research
  Food and Drug Administration
  National Center for Complementary and Integrative Health
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  National Institute of Biomedical Imaging and Bioengineering
  National Institute of Neurological Disorders and Stroke
  Office of Behavioral and Social Sciences Research
  Office of Research on Women's Health
  Application Receipt Date(s): April 14, 2023
  
  

• Accelerating Data and Metadata Standards in the Environmental Health Sciences (R24 Clinical Trial Not Allowed)
  (RFA-ES-23-002)
  National Institute of Environmental Health Sciences
  Application Receipt Date(s): May 10, 2023
  
  

• Pediatric Heart Network Clinical Research Centers (UM1 Clinical Trial Optional)
  (RFA-HL-24-001)
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): May 12, 2023
  
  

• Limited Competition: Pediatric Heart Network for the Data Coordinating Center (U24 Clinical Trial Not Allowed)
  (RFA-HL-24-002)
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): May 12, 2023
  
  

• Programs for Inclusion and Diversity Among Individuals Engaged in Health-Related Research (PRIDE) Coordination Center (U24 Clinical Trial Not Allowed)
  (RFA-HL-24-003)
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): March 10, 2023
  
  

• Programs for Inclusion and Diversity Among Individuals Engaged in Health-Related Research (PRIDE) (R25 Clinical Trial Not Allowed)
  (RFA-HL-24-004)
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): March 10, 2023
  
  

• Using Just-in-Time Adaptive Interventions to Optimize Established Adolescent Mental Health Treatments (R61/R33 Clinical Trial Required)
  (RFA-MH-23-170)
  National Institute of Mental Health
  Application Receipt Date(s): February 22, 2023
  
  

• Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
  (RFA-NS-23-012)
  National Institute of Neurological Disorders and Stroke
  Office of the Director, NIH
  Application Receipt Date(s): March 23, 2023
  
  

• Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed)
  (RFA-OD-23-001)
  Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs
  Application Receipt Date(s): Multiple dates, see announcement.