PAR-25-331 - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

Active NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Digital Technology for Early Detection and Monitoring of Alzheimers Disease (AD) and AD-Related Dementias (ADRD) NOT-AG-24-043 NIA , NLM Jan 21, 2025 Nov 17, 2027 R21, R01
Notice of Special Interest (NOSI): Genetic Underpinnings of Endosomal Trafficking as a Pathological Hub in Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) NOT-AG-24-029 NIA Jan 17, 2025 Nov 17, 2027 R21, R01
Notice of Special Interest (NOSI): Common Mechanisms and Interactions Among Neurodegenerative Diseases NOT-AG-24-031 NIA Jan 15, 2025 Nov 17, 2027 R21, R01
Notice of Special Interest (NOSI): Understanding Alzheimer's Disease in the Context of the Aging Brain NOT-AG-24-032 NIA Jan 13, 2025 Nov 17, 2027 R01, R21
Notice of Special Interest (NOSI): Selective Cell and Network Vulnerability in Aging and Alzheimers Disease NOT-AG-24-033 NIA Jan 10, 2025 Nov 17, 2027 R21, R01
Notice of Special Interest (NOSI): Major Opportunities for Research in Epidemiology of Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD) and Cognitive Resilience NOT-AG-24-042 NIA Jan 8, 2025 Nov 17, 2027 R01, R21
Notice of Special Interest (NOSI): Novel Approaches to Characterizing and Diagnosing Alzheimer's Disease and Related Dementias NOT-AG-24-030 NIA Jan 8, 2025 Nov 17, 2027 R01, R21
Notice of Special Interest (NOSI): Human Cell Biology of Alzheimer's Disease Genetic Variants NOT-AG-24-039 NIA Dec 31, 2024 Nov 17, 2027 R01, R21
Notice of Special Interest (NOSI): The Role of the Immune System in Aging Brain and Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) NOT-AG-24-010 NIA Oct 2, 2024 Dec 31, 2027 R21, R01
Notice of Special Interest (NOSI): Developing and Testing Multi-level Physical Activity Interventions to Improve Health and Well-Being NOT-OD-24-058 ODP , NCCIH , NCI , NIA , NIAMS , NICHD , NIMHD , NINR , OBSSR , ODS , ORWH Feb 20, 2024 Jan 8, 2027 U24, R01, R21, R34, UG3/UH3, R03
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence/Machine Learning Tools for Improved Assessment in Biomedical and Behavioral Research NOT-CA-24-031 NCI , NHLBI , NIA , NIDA , NIMH , NINR , OBSSR , ODSS Feb 15, 2024 Jul 6, 2025 R61/R33, R01, R21, R43/R44, R34, R41/R42
Notice of Special Interest (NOSI): Firearm Injury and Mortality Prevention Research NOT-OD-23-039 OBSSR , NCCIH , NIA , NIAAA , NICHD , NIDA , NIMH , NIMHD , NINR , ODP , ORWH , SGMRO Dec 16, 2022 Feb 5, 2026 R01, R34, R21, U24, R61/R33, UG3/UH3
Notice of Special Interest: Development of Radiotracers for Diagnosis and Clinical Studies in Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) NOT-AG-22-032 NIA Sep 28, 2022 Sep 5, 2025 R43/R44, R41/R42, R01, U01, R21
Notice of Special Interest (NOSI): Research on the Health of Bisexual and Bisexual+ People NOT-OD-22-166 OD , NCCIH , NIA , NIAAA , NIAID , NICHD , NIDA , NIDCR , NIMH , NIMHD , NINDS , ODP Aug 11, 2022 May 8, 2025 K24, U01, R01, K01, R15, R03, K76, R34, K99/R00, T32, F32, UG3/UH3, R21, K23, F31
Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes NOT-OD-22-167 OBSSR , NIA , NIAAA , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINR , ODP , ORWH , SGMRO Jul 8, 2022 Oct 5, 2025 R21, R01, R34, UG3/UH3
Notice of Special Interest (NOSI): Climate Change and Health NOT-ES-22-006 NIEHS , FIC , NCI , NHGRI , NHLBI , NIA , NIAID , NIAMS , NICHD , NIDCR , NIMH , NIMHD , NINDS , NINR , NLM , ODP Jun 1, 2022 May 8, 2025 R21, F31, D43, K01, R03, K43, K99/R00, U01, U19, R01, F32, K23, F30, R21/R33

Expired NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)

For technical issues E-mail OER Webmaster