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PA-25-303 - NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) is used for the submission of applications to the following Notices of Special Interest (NOSIs)
On This Page: 79
Active NOSIs
| Title | Notice Number | Organization | Release Date |
Expiration Date |
Activity Code(s) |
|---|---|---|---|---|---|
| Notice of Special Interest (NOSI): AI/ML in Pre-Clinical Drug Development for Psychiatric Disorders | NOT-MH-25-050 | NIMH | Dec 20, 2024 | Jan 8, 2029 | R21, R01 |
| Notice of Special Interest (NOSI): Molecular and Cellular Computational Tools Supporting Fundamental Neuroscience Research in Health, Mental Illness and Developmental Processes | NOT-MH-25-045 | NIMH | Dec 20, 2024 | May 10, 2028 | R21, P50, R01, R03, R15, UG3/UH3 |
| Notice of Special Interest (NOSI): Discovery and Development of Natural Products to Treat Substance Use Disorders (SUDs) | NOT-DA-25-032 | NIDA , NCCIH | Nov 25, 2024 | Jan 8, 2029 | R01, UG3/UH3, U01, R21 |
| Notice of Special Interest (NOSI): Basic and Translational Oral Health Research Related to HIV/AIDS | NOT-DE-25-038 | NIDCR | Sep 26, 2024 | Jan 8, 2028 | R01, R21 |
| Notice of Special Interest (NOSI): Consequences of Prenatal Fentanyl Exposure | NOT-DA-26-003 | NIDA | Sep 13, 2024 | Sep 8, 2028 | R21, R01, R03 |
| Notice of Special Interest (NOSI): Application of Artificial Intelligence in Treatment Development for Substance Use Disorders | NOT-DA-26-005 | NIDA | Sep 13, 2024 | Sep 8, 2028 | R03, R01, R21 |
| Notice of Special Interest (NOSI): Model-informed Drug Development (MIDD) Approaches to Facilitate the Development of Therapeutics for Substance Use Disorders | NOT-DA-26-002 | NIDA | Aug 27, 2024 | Sep 8, 2028 | R01, R21, R03 |
| Notice of Special Interest (NOSI): Stimulate Research on the Diagnosis, Treatment, and Mechanistic Understanding of Postural Orthostatic Tachycardia Syndrome (POTS) | NOT-HL-24-018 | NHLBI , NINDS , OD , ORWH | Aug 13, 2024 | Jan 8, 2028 | UG3/UH3, R01, K08, K99/R00, K01, R21, K25, K23 |
| Notice of Special Interest (NOSI): Fundamental Science Research on Complementary and Integrative Health Approaches, Including Natural Products or Mind and Body Interventions | NOT-AT-24-041 | NCCIH | Aug 13, 2024 | Oct 18, 2027 | R21, R01 |
| Notice of Special Interest (NOSI): Supporting Research Using the Resources from the Osteoarthritis Initiative (OAI) | NOT-AR-24-019 | NIAMS , NIA | Aug 8, 2024 | Sep 8, 2027 | R01, R21 |
| Notice of Special Interest (NOSI): Research Related to Neuroethical Considerations for Neurological Diseases | NOT-NS-24-073 | NINDS | Jul 9, 2024 | Oct 16, 2027 | R03, R21, R01 |
| Notice of Special Interest (NOSI): Advancing Research on SUD with brain-based computational models | NOT-DA-26-001 | NIDA | Jul 2, 2024 | Sep 8, 2027 | R01, R21, R61/R33, K01, R15, R03, K99/R00 |
| Notice of Special Interest (NOSI): Improving Adherence to Treatment and Prevention Regimens and Maintenance of Health Behaviors to Promote Health | NOT-OD-24-146 | OBSSR , NCCIH , NCI , NEI , NHLBI , NIA , NIDA , NIMH , NIMHD , NINR , OAR , ODP , ORWH | Jun 24, 2024 | Jul 14, 2027 | P01, P30, R01, R03, UG3/UH3, R34, U24, R41/R42, R21, R43/R44, R21/R33, R61 |
| Notice of Special Interest (NOSI): Research Opportunities Centering the Health of Women Across the HIV Research Continuum | NOT-OD-24-119 | ORWH , FIC , NCCIH , NCI , NIA , NIAAA , NIAID , NIAMS , NICHD , NIDA , NIDDK , NIMH , NIMHD , NINDS , OAR , OBSSR , SGMRO | May 21, 2024 | Jan 8, 2026 | K99/R00, R01, R34, F32, K23, K25, K02, R15, K01, K43, R21, K24, R61/R33, K08, F30, R03, DP1, U34, F31, T32, R36 |
| Notice of Special Interest (NOSI): Exploring the Effects of Endocannabinoids and Exogenous Cannabinoids on Brain Development | NOT-DA-25-030 | NIDA | Apr 30, 2024 | May 8, 2028 | R01, K01, K25, R21, R03, K08, K99/R00 |
| Notice of Special Interest: Womens Health Research | NOT-OD-24-079 | ORWH , FIC , NCATS , NCCIH , NCI , NEI , NHGRI , NHLBI , NIA , NIAAA , NIAID , NIAMS , NIBIB , NICHD , NIDA , NIDCD , NIDCR , NIDDK , NIEHS , NIGMS , NIMH , NIMHD , NINDS , NINR , NLM , OAR , OBSSR , ODP , ODS , ODSS | Mar 26, 2024 | Nov 5, 2027 | R15, R01, K01, R16, K08, R21, K43, F31, R43/R44, R41/R42, F30, R03, K23, F32, R34 |
| Notice of Special Interest (NOSI): U.S. Health in the International Perspective | NOT-AG-24-004 | NIA | Mar 6, 2024 | May 8, 2027 | R01, R03 |
| Notice of Special Interest (NOSI): Developing and Testing Multi-level Physical Activity Interventions to Improve Health and Well-Being | NOT-OD-24-058 | ODP , NCCIH , NCI , NIA , NIAMS , NICHD , NIMHD , NINR , OBSSR , ODS , ORWH | Feb 20, 2024 | Jan 8, 2027 | U24, R01, R21, R34, UG3/UH3, R03 |
| Notice of Special Interest (NOSI): Determining the Tri-directional Relationship Among Oral Health, Nutrition, and Comprehensive Health | NOT-DE-24-011 | NIDCR | Feb 12, 2024 | Sep 8, 2027 | R21, R01 |
| Notice of Special Interest (NOSI): Neuromodulatory Control of Circuits Underlying Mental Health Relevant Behaviors | NOT-MH-24-100 | NIMH | Jan 2, 2024 | May 10, 2027 | R15, R01, P50, R21, R03 |
| Notice of Special Interest (NOSI): Behavioral Tasks Targeting Brain Systems Relevant to Anhedonia | NOT-MH-24-130 | NIMH | Dec 20, 2023 | Jan 8, 2027 | R01 |
| Notice of Special Interest (NOSI): Addressing Health Disparities and Advancing Health Equity in NIDDK Diseases | NOT-DK-24-007 | NIDDK | Dec 20, 2023 | Jan 8, 2027 | K23, R01, K08, RC2, K99/R00, K01, R03, K25, R43/R44, U01, R21, R41/R42, DP1, U34 |
| Notice of Special Interest (NOSI): Quantum Sensing Technologies in Biomedical Applications | NOT-EB-23-022 | NIBIB , NCATS , NCI , NEI , NHLBI , NIGMS | Dec 13, 2023 | Jan 27, 2027 | R35, RM1, R21, R01, U01, R15, R13, K99/R00 |
| Notice of Special Interest: Health Influences of Gender as a Social and Structural Variable | NOT-OD-24-038 | ORWH , FIC , NCI , NHLBI , NIA , NIAID , NICHD , NIDA , NIMH , NINDS , OAR , SGMRO | Dec 8, 2023 | Oct 1, 2025 | K08, R01, K23, R21, K01, R03, F31, R34 |
| Notice of Special Interest (NOSI): Data Informed, Place-Based Community-Engaged Research to Advance Health for All | NOT-HL-23-110 | NHLBI , NCI , NIDCR , NIEHS , NIMH , NIMHD , NINR , OBSSR , ODP , ORWH | Nov 28, 2023 | Jan 8, 2027 | R01, R34, R21, UG3/UH3, K01, R03, P01, P50, K08, K23 |
| Notice of Special Interest (NOSI): Tackling Acquisition of Language in Kids (TALK) R01 Research Projects | NOT-DC-24-010 | NIDCD , NICHD | Nov 24, 2023 | Nov 6, 2026 | R01 |
| Notice of special interest (NOSI): Adopting Techniques and Tools Developed from the BRAIN Initiative Toward NIMH Strategic Research Priorities | NOT-MH-24-290 | NIMH | Oct 25, 2023 | May 10, 2027 | P50, R01, R21, R03, R15 |
| Notice of Special Interest (NOSI): The Road to Prevention of Stillbirth | NOT-HD-23-021 | NICHD | Oct 3, 2023 | Nov 17, 2026 | F31, R03, R15, K08, R01, R21, F30, U24, R43/R44, K23, R41/R42, R25, S06, F32, U01 |
| Notice of Special Interest in Research on Family Support and Rejection in the Health and Well-Being of SGM Populations | NOT-OD-23-166 | OD , NCI , NIA , NIAMS , NICHD , NIDDK , NIMH , NIMHD , OBSSR , ODP , ORWH , THRO | Aug 28, 2023 | May 8, 2026 | R21, R15, R01, R34, K25, K99/R00, K01, R03, P01, K08, K23 |
| Notice of Special Interest (NOSI): Epidemiology and Prevention in Alcohol Research | NOT-AA-23-018 | NIAAA , NCI | Aug 24, 2023 | Sep 6, 2026 | R03, R21, R01, UG3/UH3, R61/R33 |
| Notice of Special Interest (NOSI): Maternal Health and the Dental, Oral, and Craniofacial Development of their Children | NOT-DE-23-005 | NIDCR | Aug 3, 2023 | Mar 17, 2026 | R21, R01 |
| Notice of Special Interest (NOSI): Lymphatic System in Health and Disease (R01) | NOT-HL-23-099 | NHLBI , NCCIH , NIAMS , NIDCR | Jul 24, 2023 | Sep 8, 2026 | R01 |
| Notice of Special Interest (NOSI): Neuropathogenesis of CNS Complications Associated with HIV | NOT-MH-23-280 | NIMH , NINDS | Jun 15, 2023 | Sep 8, 2026 | K24, K08, R01, K01, K23, R15, K99/R00, F30, F32, K43, F31, T32, R03, R21, R25 |
| Notice of Special Interest (NOSI): Eradication of HIV-1 from Central Nervous System Reservoirs | NOT-MH-23-260 | NIMH , NINDS | Jun 15, 2023 | Sep 8, 2026 | R21, K43, K01, R25, K08, K99/R00, R01, F30, F32, T32, R03, R15, F31, K23, K24 |
| Notice of Special Interest (NOSI): Clinical Studies of CNS Complications in People with HIV | NOT-MH-23-255 | NIMH , NINDS | Jun 15, 2023 | Sep 8, 2026 | K43, K01, R25, K99/R00, R21, K08, F30, T32, R01, F32, F31, R03, R15, K23, K24 |
| Notice of Special Interest (NOSI): Pre-Clinical Research on Gene Therapies for Rare Genetic Neurodevelopmental Disorders | NOT-MH-23-236 | NIMH | Apr 28, 2023 | Sep 8, 2026 | R01 |
| Notice of Special Interest (NOSI): NIMH Planning Grants for Natural History Studies of Rare Genetic Neurodevelopmental Disorders | NOT-MH-23-235 | NIMH | Apr 28, 2023 | Sep 8, 2026 | R01 |
| Notice of Special Interest: Advancing mHealth Interventions for Understanding and Preventing Alcohol-Related Domestic Violence | NOT-AA-23-003 | NIAAA | Mar 6, 2023 | Sep 8, 2026 | R01, R21, R34, K99/R00 |
| Notice of Special Interest (NOSI): Addressing Health Disparities Among Immigrant Populations Through Effective Interventions | NOT-MD-23-003 | NIMHD , NCI , NEI , NIAAA , NIDA , ORWH | Feb 6, 2023 | Jun 6, 2026 | R01 |
| Notice of Special Interest (NOSI): Pharmacogenomic Approaches to Enhancing HIV and Substance Use Disorder (SUD) Treatment Strategies, A jump into Precision Medicine. | NOT-DA-24-001 | NIDA | Jan 26, 2023 | May 8, 2026 | R01, R03 |
| Notice of Special Interest (NOSI): Computational and Statistical Methods to Enhance Discovery from Health Data | NOT-LM-23-001 | NLM | Jan 19, 2023 | Jan 8, 2026 | R01 |
| Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases | NOT-DA-22-048 | NIDA , NCI , NIDCR | Jan 9, 2023 | Jan 8, 2026 | R01, R21, DP2, DP1, K99/R00, K01, R36, K08, R15, K24 |
| Notice of Special Interest (NOSI): Firearm Injury and Mortality Prevention Research | NOT-OD-23-039 | OBSSR , NCCIH , NIA , NIAAA , NICHD , NIDA , NIMH , NIMHD , NINR , ODP , ORWH | Dec 16, 2022 | Feb 5, 2026 | R01, R34, R21, U24, R61/R33, UG3/UH3 |
| Notice of Special Interest (NOSI): Research to Address Ending the HIV Epidemic Initiative Goals Relevant to Substance Using Populations At-Risk for or Living with HIV | NOT-DA-23-013 | NIDA | Dec 8, 2022 | Jan 8, 2027 | R34, R01 |
| Notice of Special Interest (NOSI): Chemsex and HIV: prevalence, medical/psychosocial consequences, and treatment | NOT-DA-24-002 | NIDA | Nov 14, 2022 | Jan 8, 2026 | R21, R01, R03 |
| Notice of Special Interest (NOSI): Explainable Artificial Intelligence for Decoding and Modulating Neural Circuit Activity Linked to Behavior | NOT-MH-23-110 | NIMH , ORWH | Nov 8, 2022 | Feb 6, 2027 | R01 |
| Notice of Special Interest (NOSI): Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R01, R21, R03) | NOT-DA-23-012 | NIDA | Nov 2, 2022 | Feb 8, 2026 | R01, R03, R21 |
| Notice of Special Interest (NOSI): Research on the Impact of Policy Changes and Emerging and Evolving Public Health Crises on NIDA Populations of Interest | NOT-DA-22-084 | NIDA | Oct 20, 2022 | Jan 8, 2026 | R15, R21, R01, R03 |
| Notice of Special Interest (NOSI): Promoting Mechanistic Research on Therapeutic and Other Biological Properties of Minor Cannabinoids and Terpenes | NOT-AT-22-027 | NCCIH , NCI , NEI , NIA , NIAAA , NIDA , NIDCR , NINDS , ODS , ORWH | Jul 27, 2022 | Jul 1, 2025 | R21, R01, UG3/UH3 |
| Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations | NOT-MD-22-012 | NIMHD , NCCIH , NCI , NHGRI , NIA , NIAID , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIDDK , NIEHS , NINDS , NINR , ODP , ORWH | Jul 11, 2022 | Aug 8, 2025 | R01, K08, K99/R00, K01, K23, R21, K25, K18, R03, P50, F99/K00, UG3/UH3, R34, R25, U01 |
| Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes | NOT-OD-22-167 | OBSSR , NIA , NIAAA , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINR , ODP , ORWH | Jul 8, 2022 | Oct 5, 2025 | R21, R01, R34, UG3/UH3 |
| Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities | NOT-OD-22-154 | ODP , NCI , NHLBI , NIAAA , NIAMS , NIDCR , NIEHS , NIMHD , NINDS , OBSSR , ORWH | Jun 14, 2022 | Oct 6, 2025 | R01, R21, R34, R03, UG3/UH3 |
| Notice of Special Interest (NOSI): Basic Mechanisms of Cannabis and Cannabinoid Action in Cancer | NOT-CA-22-085 | NCI | May 5, 2022 | Jul 5, 2027 | K22, R01, K08, K01, R21, R03, K99/R00 |
| Notice of Special Interest: Achieving Tissue Robustness Through Harnessing Immune System Plasticity | NOT-DE-22-005 | NIDCR | Apr 26, 2022 | Sep 9, 2025 | R21, R01 |
| Notices of Special Interest (NOSI): High Priority Areas in Genetics, Epigenetics, and Developmental Neuroscience Branch in the Division of Neuroscience and Behavior | NOT-DA-23-004 | NIDA | Apr 14, 2022 | Sep 9, 2025 | R01 |
| Notice of Special Interest (NOSI) Pediatric COVID-19 and Respiratory Viral Co-infection | NOT-HL-22-004 | NHLBI , NICHD , NIAID | Dec 21, 2021 | Sep 8, 2025 | R01, R21 |
| Notice of Special Interest (NOSI): Stimulating Intervention Research to Reduce Cardiopulmonary Impacts of Particulate Matter in Air Pollution among High-Risk Populations | NOT-HL-20-788 | NHLBI , NIEHS | Jul 16, 2020 | Sep 8, 2025 | R01 |
Expired NOSIs
| Title | Notice Number | Organization | Release Date |
Expiration Date |
Activity Code(s) |
|---|---|---|---|---|---|
| Notice of Special Interest (NOSI): Research Council of Finland (RCF) National Institutes of Health (NIH) Partnership Program | NOT-OD-24-040 | OD NCI NEI NIA NIAID NIAMS NIBIB NIDCR NIDDK | Dec 14, 2023 | Jan 8, 2025 | R01 |
| Notice of Special Interest (NOSI): The Neural Mechanisms of Multi-Dimensional Emotional and Social Representation | NOT-MH-23-120 | NIMH | Dec 7, 2022 | Jan 8, 2025 | R21, R01, R03, R15 |
| Notice of Special Interest (NOSI): Research on the Impact of Policy Changes and Emerging and Evolving Public Health Crises on NICHD Populations of Interest | NOT-HD-22-038 | NICHD NIDA | Sep 14, 2022 | Jan 8, 2025 | R15, R03, R01, R21 |
| Notice of Special Interest (NOSI): Research on the Health of Bisexual and Bisexual+ People | NOT-OD-22-166 | OD NCCIH NIA NIAAA NIAID NICHD NIDA NIDCR NIMH NIMHD NINDS ODP | Aug 11, 2022 | May 8, 2025 | K24, U01, R01, K01, R15, R03, K76, R34, K99/R00, T32, F32, UG3/UH3, R21, K23, F31 |
| Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening | NOT-OD-22-179 | ODP NIA NIAAA NIAMS NICHD NIDA NIDCD NIDCR NIMH NIMHD NINDS NINR ODS ORWH | Jul 14, 2022 | May 8, 2025 | R21, R01, R61/R33, UG3/UH3, R34, U01 |
| Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan | NOT-OD-22-178 | ODP NCI NIA NIAAA NIAMS NICHD NIDA NIDCD NIDCR NIMH NIMHD NINDS NINR ODS ORWH | Jul 14, 2022 | Apr 16, 2025 | R21, R01, UG3/UH3, R61/R33, R34, R03 |
| Notice of Special Interest (NOSI): Climate Change and Health | NOT-ES-22-006 | NIEHS FIC NCI NHGRI NHLBI NIA NIAID NIAMS NICHD NIDCR NIMH NIMHD NINDS NINR NLM ODP | Jun 1, 2022 | May 8, 2025 | R21, F31, D43, K01, R03, K43, K99/R00, U01, U19, R01, F32, K23, F30, R21/R33 |
| Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project | NOT-OD-22-123 | OD NCI NEI NHLBI NIA NIAMS NICHD NIDCD NIDCR NIMHD NINDS | May 26, 2022 | May 1, 2025 | R01 |
| Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan | NOT-OD-22-106 | ODP NCI NIA NIAAA NIAMS NICHD NIDA NIDCD NIDCR NIMH NIMHD NINDS NINR ODS ORWH | May 12, 2022 | May 8, 2025 | R03, R01, R34, R21, UG3/UH3, R61/R33, 333 |
| Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening | NOT-OD-22-107 | ODP NIA NIAAA NIAMS NICHD NIDA NIDCD NIDCR NIMH NIMHD NINDS NINR ODS ORWH | May 12, 2022 | May 8, 2025 | 333, R01, R34, R21, R61/R33, U01, UG3/UH3 |
| Notice of Special Interest (NOSI): Public Health Research on Cannabis | NOT-DA-22-003 | NIDA | Feb 18, 2022 | May 5, 2025 | R21, R01, 333, R03 |
| Notice of Special Interest: NIMH Priorities on Research on Aggression and Violence Against Others | NOT-MH-22-095 | NIMH | Feb 3, 2022 | Jan 8, 2025 | R36, R01, R34, R21, F32, R21/R33, R03, R61/R33, U01, K08, R15, K23, P50, F30, K99/R00, F31, K22, K01 |
| Notice of Special Interest: Neuro-Glia Mechanisms Governing Complex Behaviors (R01 Clinical Trial Optional) | NOT-MH-22-090 | NIMH | Feb 3, 2022 | May 8, 2025 | R21, R01 |
| Notice of Special Interest (NOSI): Research to Prevent Drug Use, Misuse and Addiction | NOT-DA-23-001 | NIDA ODP | Jan 21, 2022 | May 8, 2025 | R01, R21, R34, R03 |
| Notice of Special Interest (NOSI): COVID-19 Pandemic Mental Health Research | NOT-MH-22-100 | NIMH | Jan 19, 2022 | Jan 8, 2025 | R21, R34, R01 |
| Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging | NOT-AG-22-004 | NIA | Dec 22, 2021 | Jan 8, 2025 | F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19 |
| Notice of Special Interest (NOSI): Mechanistic studies on the impact of substance use in sex and gender differences in HIV-associated neurocognitive disorders | NOT-DA-22-047 | NIDA ORWH | Nov 19, 2021 | Jan 8, 2025 | R21, R01 |
| Notice of Special Interest (NOSI): Secondary Analysis of Posttraumatic Psychopathology Data | NOT-MH-22-045 | NIMH | Nov 18, 2021 | Jan 8, 2025 | R01, R21, K08, F30, K01, K23, K22, F32, F31, R03, R36, K99/R00, R15, F99/K00 |
| Notice of Special Interest (NOSI): Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities | NOT-DE-21-013 | NIDCR NCI NIMHD | Oct 7, 2021 | Jan 8, 2025 | R21, R01 |
| Notice of Special Interest (NOSI): Evaluation of sex differences on HIV-associated comorbidities in the context of stimulant use | NOT-DA-21-020 | NIDA | Sep 9, 2021 | Jan 8, 2025 | R01 |
| Notice of Special Interest (NOSI): Advancing HIV/AIDS Research through Computational Neuroscience | NOT-DA-21-030 | NIDA | Jun 22, 2021 | Jan 8, 2025 | R01, R21, R03, DP2, DP1, K99/R00, K01, R36, P01, R15, K24 |
| Notice of Special Interest: Advanced Computational Approaches to Elucidate Disease Pathology and Identify Novel Therapeutics for Addiction | NOT-DA-21-004 | NIDA | May 17, 2021 | Jan 8, 2025 | R01 |
