NIH Guide to Grants and Contracts

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Results: 26 to 50 of 1375

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Addressing Chronic Wound Trajectories Through Social Genomics Research (R21 Clinical Trial Optional) - PA-17-493

Organization: NINR 

Posting Date: 09-27-2017 

Expiration Date: 01-08-2021 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate clinical research that applies a social genomics approach to chronic wound risk, presence, progression, and healing. The field of social genomics focuses on how the social environment influences gene expression, and how this gene expression may in turn impact health outcomes. Chronic wounds (e.g., diabetic ulcers, venous or arterial ulcers) are multidimensional and, as such, there is benefit to a holistic approach that goes beyond a focus on the wound (i.e., repairing the skin and underlying tissue) to include an approach that focuses on the person with the wound. A better understanding of social environmental factors (positive and negative) and associated molecular mechanisms is needed to advance therapeutic strategies aimed at reducing chronic wound risk in addition to improving healing outcomes and quality of life. 

Addressing Health Disparities in NIDDK Diseases (R01 - Clinical Trial Not Allowed) - PA-18-412

Organization: NIDDK 

Posting Date: 11-17-2017 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites research to understand and mitigate health disparities in the development, diagnosis, and treatment of diseases of high priority to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Research is encouraged in the following high priority diseases: diabetes and other endocrine and metabolic diseases; obesity; nutrition-related disorders; hepatitis C; gallbladder disease; H. Pylori infection; complications of sickle cell disease within the NIDDK mission areas; kidney diseases; urologic diseases; metabolic, gastrointestinal, hepatic, and renal complications from infection with HIV; and mechanistic research in hematologic diseases, including studies in abnormal hemoglobin synthesis. This FOA will not support multi-center clinical studies or Clinical Trials. Animal research is allowed if the research is a clinically relevant model of a NIDDK mission area disease in a minority population. 

Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R01 Clinical Trial Optional) - PA-18-284

Organization: NIMHD 

Posting Date: 11-01-2017 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support innovative research to develop and implement effective interventions to address health disparities among U.S. immigrant populations.  

Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R01) - PA-17-043

Organization: NIMHD 

Posting Date: 11-01-2016 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support innovative research to develop and implement effective interventions to address health disparities among U.S. immigrant populations.  

Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R21 Clinical Trial Optional) - PA-18-285

Organization: NIMHD 

Posting Date: 11-01-2017 

Expiration Date: 01-08-2020 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support and accelerate innovative exploratory and developmental research to develop and test feasibility of effective interventions to address health disparities among U.S. immigrant populations.  

Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R21) - PA-17-044

Organization: NIMHD 

Posting Date: 11-01-2016 

Expiration Date: 01-08-2020 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support and accelerate innovative exploratory and developmental research to develop and test feasibility of effective interventions to address health disparities among U.S. immigrant populations.  

Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R01 Clinical Trial Optional) - PA-18-147

Organization: NINR 

Posting Date: 11-07-2017 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate clinical research addressing behavioral and psychological symptoms of dementia (BPSD) and the association of BPSD with unmet physical, social, or environmental needs in persons with dementia. 

Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R01) - PA-17-014

Organization: NINR 

Posting Date: 10-18-2016 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate clinical research addressing behavioral and psychological symptoms of dementia (BPSD) and the association of BPSD with unmet physical, social, or environmental needs in persons with dementia. 

Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R21 Clinical Trial Optional) - PA-18-165

Organization: NINR 

Posting Date: 11-07-2017 

Expiration Date: 01-08-2020 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate clinical research addressing behavioral and psychological symptoms of dementia (BPSD) and the association of BPSD with unmet physical, social, or environmental needs in persons with dementia. 

Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R21) - PA-17-013

Organization: NINR 

Posting Date: 10-18-2016 

Expiration Date: 01-08-2020 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate clinical research addressing behavioral and psychological symptoms of dementia (BPSD) and the association of BPSD with unmet physical, social, or environmental needs in persons with dementia. 

Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations (R01) - PA-17-041

Organization: NIMHD 

Posting Date: 11-01-2016 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support innovative research to understand uniquely associated factors (biological, behavioral, sociocultural, and environmental) that contribute to health disparities or health advantages among U.S. immigrant populations.  

Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations (R21) - PA-17-042

Organization: NIMHD 

Posting Date: 11-01-2016 

Expiration Date: 01-08-2020 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support innovative exploratory and developmental research to understand uniquely associated factors (biological, behavioral, sociocultural, and environmental) that contribute to health disparities or health advantages among U.S. immigrant populations  

Administrative Supplement for the NINDS Research Education Program for Residents and Fellows in Neurology, Neurosurgery, Neuropathology, Neuroradiology and Emergency Medicine (Admin Supp) - PA-17-442

Organization: NINDS 

Posting Date: 07-28-2017 

Expiration Date: 11-01-2019 

Activity Code: (Admin Supp) 

Summary: This Funding Opportunity Announcement (FOA) encourages administrative supplements for the NINDS Research Education Program for Residents and Fellows in Neurology, Neurosurgery, Neuropathology, Neuroradiology and Emergency Medicine (R25, PAR-13-384 and subsequent reissuances)  

Administrative Supplements for Complementary Health Practitioner Research Experience (Admin Supp) - PA-16-013

Organization: NCCIH  (formerly NCCAM)

Posting Date: 10-26-2015 

Expiration Date: 09-02-2018 

Activity Code: (Admin Supp) 

Summary: NCCIH encourages applications for administrative supplements to NCCIH-supported awards (see relevant Activity Codes above) to support complementary health practitioners in an intensive supervised clinical research experience that will lead to a better understanding of and practical experience in complementary and integrative health research. For this FOA, clinicians may include (but are not limited to) licensed acupuncturists, chiropractors, naturopathic medicine practitioners, and massage therapists. Funding is available for one year with an option to renew for a second year. to conduct clinical research associated with the parent program. This initiative is focused on providing a research experience for complementary health practitioners and is not intended to support clinical residency training or other clinical practitioner training. 

Administrative Supplements for Research on Dietary Supplements (Admin Supp) - PA-17-307

Organization: ODS 

Posting Date: 06-07-2017 

Expiration Date: 04-16-2018 

Activity Code: (Admin Supp) 

Summary: This Funding Opportunity Announcement (FOA) announces the availability of administrative supplements to support research in which the supplemental funding would investigate the role of dietary supplements and/or their ingredients in health maintenance and disease prevention. Parent awards need not be focused on dietary supplements; this FOA may provide support to include dietary supplements within the scope of relevant research projects. Research interests of ODS are not limited to specific health conditions, organ systems or population groups. ODS supports all types of research, including pre-clinical, clinical, behavioral, and epidemiological. Additionally, ODS supports research and training programs that build future research capacity for studying the role of dietary supplements in health and disease prevention. Primary consideration for support will be given to applications that stimulate dietary supplement research where it is lacking or lagging, clarify gaps, opportunities and balance between benefits and risks where data are in conflict, target special population groups where additional science on dietary supplements is needed, and focus on the use of dietary supplements in improving or maintaining health and reducing the risk of chronic disease. This FOA will not support new clinical trials.  

Administrative Supplements for the U.S.-Japan Brain Research Cooperative Program (BRCP) - U.S. Entity (Admin Supplement) - PA-17-326

Organization: NINDS 

Posting Date: 07-18-2017 

Expiration Date: 09-19-2019 

Activity Code: (Admin Supp) 

Summary: The National Institutes of Health (NIH) announces the continuation of the U.S. entity of the U.S.-Japan Brain Research Cooperative Program (BRCP). This administrative supplement program will provide funds to research projects that are currently supported by the participating NIH Institutes and Centers. 

Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Admin Supp) - PA-16-287

Organization: NIH 

Posting Date: 05-24-2016 

Expiration Date: 05-26-2019 

Activity Code: (Admin Supp) 

Summary: The National Institutes of Health (NIH) hereby notify Program Directors/Principal Investigators (PD(s)/PI(s)) holding specific types of NIH research grants listed in the full Funding Opportunity Announcement (FOA) that funds may be available for administrative supplements to meet increased costs that are within the scope of the approved award, but were unforeseen when the new or renewal application or grant progress report for non-competing continuation support was submitted. Applications for administrative supplements are considered prior approval requests (as described in Section 8.1.2.11 of the NIH Grants Policy Statement) and will be routed directly to the Grants Management Officer of the parent award. 

Administrative Supplements to Promote Research Collaborations on Fusion Oncoproteins as Drivers of Childhood Cancer (Admin Supp) - PA-17-138

Organization: NCI 

Posting Date: 01-26-2017 

Expiration Date: 03-29-2018 

Activity Code: (Admin Supp) 

Summary: This Administrative Supplement funding opportunity announcement is part of the Cancer Moonshot initiative to accelerate cancer research, and was developed in response to a recommendation from the Blue Ribbon Panel of experts charged with advising the National Cancer Advisory Board on the exceptional scientific opportunities that could be accelerated through this initiative. Based on the recommendation to intensify research and form highly dynamic and collaborative networks of investigators to advance our understanding of fusion oncoproteins as drivers of childhood cancers, this FOA supports supplemental funds to current NCI-funded research projects for new interdisciplinary collaborations to perform research within the scientific scope of the parent grant that will lead to better understanding of the mechanisms of action of fusion oncoproteins as drivers of childhood sarcomas, brain cancers, and high risk leukemias. 

Administrative supplements for validation studies of analytical methods for dietary supplements and natural products (Admin. Suppl.) - PA-17-447

Organization: ODS 

Posting Date: 08-01-2017 

Expiration Date: 04-16-2018 

Activity Code: (Admin Supp) 

Summary: The reproducibility and comparability of dietary supplement research is enhanced through rigorous analytical characterization of key experimental materials. The publication of analytical methods which have been thoroughly validated for specific, precise, accurate, and sensitive quantitative determination of chemical constituents of dietary supplements therefore makes critical contributions to the rigor and reproducibility of biomedical research. This FOA will build on existing NIH awards to support the performance and publication of formal single-laboratory validation studies of relevant quantitative analytical methods. The methods proposed for validation must be used to identify and quantify chemical constituents (active or marker chemical compounds, adulterants, contaminants) or metabolites thereof in experimental reagents, raw materials, and/or clinical specimens (for example urine or plasma samples). Methods must have been developed or utilized in fulfillment of the active parent grants specific aims. Candidate constituents for quantitative method validation studies may include (but are not limited to): phytochemicals, nutrients, and potentially deleterious substances such as pesticides and mycotoxins. Multi-laboratory validation studies will not be supported through this FOA.  

Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 - Clinical Trial Not Allowed) - RFA-CA-18-005

Organization: NCI 

Posting Date: 11-20-2017 

Expiration Date: 09-29-2018 

Activity Code: R33 

Summary: This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies that improve the quality of the samples used for cancer research or clinical care. This includes new capabilities to address issues related to pre-analytical degradation of targeted analytes during the collection, processing, handling, and/or storage of cancer-relevant biospecimens. This FOA solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still requires further development and rigorous validation to encourage adoption by the research community. The overall goal is to support the development of highly innovative technologies capable of maximizing or otherwise interrogating the quality and utility of biological samples used for downstream analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and handling under diverse conditions. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, epidemiology, or address issues associated with cancer health disparities, by reducing pre-analytical variations that affect biospecimen sample quality. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program. 

Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 - Clinical Trial Not Allowed) - RFA-CA-18-003

Organization: NCI 

Posting Date: 11-20-2017 

Expiration Date: 09-29-2018 

Activity Code: R33 

Summary: This Funding Opportunity Announcement (FOA) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies offering novel capabilities for targeting, probing, or assessing molecular and cellular features of cancer biology for basic or clinical cancer research. This FOA solicits R33 applications where major feasibility gaps for the technology or methodology have been overcome, as demonstrated with supportive preliminary data, but still requires further development and rigorous validation to encourage adoption by the research community. Well-suited applications must offer the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, control, epidemiology, and/or address issues associated with cancer health disparities. Technologies proposed for development may be intended to have widespread applicability but must be focused on improving molecular and/or cellular characterizations of cancer. Projects proposing application of existing technologies where the novelty resides in the biological or clinical target/question being pursued are non-responsive to this solicitation and will not be reviewed. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.  

Advanced Development of Informatics Technologies for Cancer Research and Management (U24) - PAR-15-331

Organization: NCI 

Posting Date: 08-18-2015 

Expiration Date: 11-21-2018 

Activity Code: U24 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U24) applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum, including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA focuses on emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research.In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from users and collaborators throughout the development process should be included. Potential applicants who are interested in early-stage development or informatics resource sustainment should consult companion FOAs listed above.  

Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50) - PAR-16-354

Organization: NIMH 

Posting Date: 07-06-2016 

Expiration Date: 05-18-2018 

Activity Code: P50 

Summary: This Funding Opportunity Announcement (FOA) invites applications for centers to support transdisciplinary teams of clinical and mental health services researchers, behavioral scientists, social scientists, health information and communications technologists, health systems engineers, decision scientists, and mental health stakeholders (e.g., service users, family members, clinicians, payers) to engage in high-impact studies that will significantly advance clinical practice and generate knowledge that will fuel transformation of mental health care in the United States. Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers will support the rapid development, testing, and refinement of novel and integrative approaches for (1) optimizing the effectiveness of therapeutic or preventive interventions for mental disorders within well-defined target populations; (2) organizing and delivering optimized mental health services within real world treatment settings; and (3) continuously improving the quality, impact, and durability of optimized interventions and service delivery within diverse care systems. The ALACRITY Centers program is intended to support research that demonstrates an extraordinary level of synergy across disciplines and has a high potential for increasing the public health impact of existing and emerging mental health interventions and service delivery strategies. The Centers are intended for transdisciplinary projects that could not be achieved using standard research project grant mechanisms. The ALACRITY Centers program is also expected to provide opportunities for graduate students, postdoctoral researchers, and new investigators to participate in transdisciplinary, T2 translational mental health research.  

Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinary Aging Studies (R33) - PAR-16-368

Organization: NIA 

Posting Date: 07-13-2016 

Expiration Date: 09-08-2019 

Activity Code: R33 

Summary: This FOA invites applications that propose to support advanced-stage development and utilization of novel research infrastructure to advance the science of aging in specific areas requiring interdisciplinary partnerships or collaborations. This FOA will use the NIH Exploratory/Developmental Grants Phase II mechanism to provide support for expanded activities. Applicants are expected to have an existing research infrastructure developed either through PA-12-064, or with other NIH or non-NIH support. Through this award, investigators will develop a mature and sustainable research infrastructure to support projects that address key interdisciplinary aging research questions. 

Advances in Patient Safety through Simulation Research (R18) - PA-16-420

Organization: AHRQ 

Posting Date: 09-06-2016 

Expiration Date: 01-26-2022 

Activity Code: R18 

Summary: The Agency for Healthcare Research and Quality (AHRQ) is interested in funding a diverse set of projects that develop, test and evaluate various simulation approaches for the purpose of improving the safe delivery of health care. Simulation in health care serves multiple purposes. As a training technique, it exposes individuals and teams to realistic clinical challenges through the use of mannequins, task trainers, virtual reality, standardized patients or other forms, and allows participants to experience in real-time the consequences of their decisions and actions. The principal advantage of simulation is that it provides a safe environment for health care practitioners to acquire valuable experience without putting patients at risk. Simulation also can be used as a test-bed to improve clinical processes and to identify failure modes or other areas of concern in new procedures and technologies that might otherwise be unanticipated and serve as threats to patient safety. Yet another application of simulation focuses on the establishment of valid and reliable measures of clinical performance competency and their potential use for credentialing and certification purposes. The foremost aim of the announcement is to advance patient safety. Keeping this aim in mind, applications that address a variety of simulation techniques, clinical settings, provider groups, priority populations, and patient conditions are welcomed. 

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