NIH Guide to Grants and Contracts

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Results: 1323 to 1347 of 1370

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Transition to Independent Environmental Health Research (TIEHR) Career Transition Award (K01) - PAR-16-360

Organization: NIEHS 

Posting Date: 07-07-2016 

Expiration Date: 09-08-2019 

Activity Code: K01 

Summary: The Transitions to Independent Environmental Health (TIEHR) Career Award is a 3-year bridge scholar development program for newly independent faculty who intend to pursue research careers in environmental health sciences. At the conclusion of the career development period the candidates are expected to demonstrate they can successfully compete for research funding in the environmental health sciences. 

Translational Bioinformatics Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease (R01) - PAR-17-032

Organization: NIA 

Posting Date: 10-25-2016 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: This funding opportunity invites applications that integrate the use of computational approaches to identify individual drugs currently used for other conditions with potential to be efficacious in AD or AD-related dementias (as single drugs or as drug combinations) with proof-of-concept efficacy studies in cell-based models, animal models and/or humans.  

Translational Neural Devices (U44 - Clinical Trial Required) - RFA-NS-18-012

Organization: NINDS 

Posting Date: 11-08-2017 

Expiration Date: 10-22-2020 

Activity Code: U44 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from Small Business Concerns (SBCs) to pursue translational activities and small clinical studies to advance the development of therapeutic and diagnostic devices for disorders that affect the nervous or neuromuscular systems. The translational device activities, including translational bench and animal studies, are expected to lead to submission of an Investigational Device Exemption (IDE) to the U.S. Food and Drug Administration (FDA) or Institutional Review Board (IRB) application for a Non-Significant Risk (NSR) study. This cooperative agreement will also support the subsequent small clinical study to collect safety and effectiveness data required to support a marketing application or to inform final device design. 

Translational Neural Devices (UG3/UH3 - Clinical Trial Required) - RFA-NS-18-011

Organization: NINDS 

Posting Date: 11-08-2017 

Expiration Date: 10-22-2020 

Activity Code: UG3/UH3 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications to pursue translational activities and small clinical studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. The translational device activities, including translational bench and animal studies, are expected to lead to submission of an Investigational Device Exemption (IDE) to the U.S. Food and Drug Administration (FDA) or Institutional Review Board (IRB) application for a Non-Significant Risk (NSR) study. This cooperative agreement will also support the subsequent small clinical study to collect safety and effectiveness data required to support a marketing application or to inform final device design. 

Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R01) - PAR-17-189

Organization: NICHD 

Posting Date: 03-03-2017 

Expiration Date: 04-04-2020 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is to encourage applications for translational and clinical research as well as clinical trials that will advance our knowledge about the underlying mechanisms of drug action, response, and safety in children at various developmental stages, and in women during pregnancy and lactation. The overall goals of the FOA are to improve the safety and effectiveness of current drugs for pediatric or obstetric patients, and to enhance the development of new drugs or a safer usage of the existing drugs for tailored therapies to meet emerging clinical needs for these special populations.  

Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R03) - PAR-17-188

Organization: NICHD 

Posting Date: 03-03-2017 

Expiration Date: 04-04-2020 

Activity Code: R03 

Summary: The purpose of this funding opportunity announcement (FOA) is to encourage applications for translational and clinical research as well as clinical trials that will advance our knowledge about the underlying mechanisms of drug action, response, and safety in children at various developmental stages, and in women during pregnancy and lactation. The overall goals of the FOA are to improve the safety and effectiveness of current drugs for pediatric or obstetric patients, and to enhance the development of new drugs or a safer usage of the existing drugs for tailored therapies to meet emerging clinical needs for these special populations.  

Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R21) - PAR-17-187

Organization: NICHD 

Posting Date: 03-03-2017 

Expiration Date: 04-04-2020 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to encourage applications for translational and clinical research as well as clinical trials that will advance our knowledge about the underlying mechanisms of drug action, response, and safety in children at various developmental stages, and in women during pregnancy and lactation. The overall goals of the FOA are to improve the safety and effectiveness of current drugs for pediatric or obstetric patients, and to enhance the development of new drugs or a safer usage of the existing drugs for tailored therapies to meet emerging clinical needs for these special populations.  

Translational Studies on Adducts for Cancer Risk Identification and Prevention (U01) - PAR-15-307

Organization: NCI 

Posting Date: 07-24-2015 

Expiration Date: 07-12-2018 

Activity Code: U01 

Summary: This Funding Opportunity Announcement (FOA) encourages clinically-relevant translational/epidemiological research projects focused on the use of adducts to cellular macromolecules, as indicators of exposures to cancer risk factors in human populations and subgroups. The priority is on projects that will focus on adductomic approaches, i.e., address some aspects of the totality of adducts. The projects are expected to be based on comprehensive use of human biospecimens for which detailed medical data are available (e.g., biospecimens from the NCI-supported cohort studies). The main emphasis of this FOA is on advancing the area of cancer detection, cancer prevention, and assessing cancer risks in human populations and subgroups. Nonetheless, studies evaluating the potential roles of adducts in cancer etiology for gene-environment interaction research may also be appropriate provided that such projects are based on appropriate sets of human biospecimens (such as specimens from cohorts studies supported by NIH).  

Trophoblast Differentiation and Function (R01) - PA-16-445

Organization: NICHD 

Posting Date: 09-23-2016 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of trophoblast differentiation and function in relation to fertility and pregnancy, including the role of the immune system. It is anticipated that fundamental knowledge gained by this research will act as a solid foundation to hasten treatments for a number of placental-based pregnancy disorders, such as implantation failure, frequent pregnancy loss, preeclampsia, fetal growth restriction, and preterm birth.  

Trophoblast Differentiation and Function (R21 Clinical Trial Optional) - PA-18-047

Organization: NICHD 

Posting Date: 11-15-2017 

Expiration Date: 01-08-2020 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of trophoblast differentiation and function in relation to fertility and pregnancy, including the role of the immune system. It is anticipated that fundamental knowledge gained by this research will act as a solid foundation to hasten treatments for a number of placental-based pregnancy disorders, such as implantation failure, frequent pregnancy loss, preeclampsia, fetal growth restriction, and preterm birth.  

Trophoblast Differentiation and Function (R21) - PA-16-444

Organization: NICHD 

Posting Date: 09-23-2016 

Expiration Date: 01-08-2020 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of trophoblast differentiation and function in relation to fertility and pregnancy, including the role of the immune system. It is anticipated that fundamental knowledge gained by this research will act as a solid foundation to hasten treatments for a number of placental-based pregnancy disorders, such as implantation failure, frequent pregnancy loss, preeclampsia, fetal growth restriction, and preterm birth.  

Turkey-US Collaborative Program for Affordable Medical Technologies (R01) - PAR-15-276

Organization: NCI 

Posting Date: 06-11-2015 

Expiration Date: 01-08-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications from research partnerships formed between scientists from U.S. and Turkey to accelerate the development of appropriate affordable diagnostic and therapeutic technologies, which address medical needs in low-middle resource settings. Appropriate medical technologies are those that are useable, cost effective, sustainable, and effective in meeting a significant clinical need in a lower-middle resource setting in different world regions. 

Typical and Atypical Patterns of Language and Literacy in Dual Language Learners (R01-Clinical Trial Optional) - PA-18-316

Organization: NIDCD 

Posting Date: 10-20-2017 

Expiration Date: 12-16-2020 

Activity Code: R01 

Summary: The purpose of this FOA is to support investigator-initiated R01 applications that will inform our understanding of the typical and atypical patterns of language and literacy development of dual language learners (DLLs) in the United States. Applicants are encouraged to take advantage of advances in the language sciences and related fields to identify and clarify specific cognitive, linguistic, neurobiological, and sociocultural factors associated with normal and impaired language and literacy acquisition in young DLL populations.  

Typical and Atypical Patterns of Language and Literacy in Dual Language Learners (R21-Clinical Trial Optional) - PA-18-328

Organization: NIDCD 

Posting Date: 10-20-2017 

Expiration Date: 12-17-2021 

Activity Code: R21 

Summary: The purpose of this FOA is to support investigator-initiated R21 applications that will inform our understanding of the typical and atypical patterns of language and literacy development of dual language learners (DLLs) in the United States. Applicants are encouraged to take advantage of advances in the language sciences and related fields to identify and clarify specific cognitive, linguistic, neurobiological, and sociocultural factors associated with normal and impaired language and literacy acquisition in young DLL populations.  

U.S. Tobacco Control Policies to Reduce Health Disparities (R01) - PAR-17-217

Organization: NCI 

Posting Date: 05-26-2017 

Expiration Date: 06-16-2020 

Activity Code: R01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support observational or intervention research focused on reducing health disparities in tobacco use in the United States. Specifically, this FOA is intended to stimulate scientific inquiry focused on innovative tobacco control policies. Applicants may propose projects in which the primary outcome of interest is on reducing tobacco use health disparities in vulnerable populations by utilizing tobacco prevention and control strategies. The long-term goal of this FOA is to reduce health disparities in health outcomes thereby reducing the excess disease burden of tobacco use within these groups. Applicants submitting applications related to health economics are encouraged to consult NOT-OD-16-025 to ensure that applications align with NIH mission priorities in health economics research. 

U.S. Tobacco Control Policies to Reduce Health Disparities (R21) - PAR-17-218

Organization: NCI 

Posting Date: 05-26-2017 

Expiration Date: 06-16-2020 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support observational or intervention research focused on reducing health disparities in tobacco use in the United States. Specifically, this FOA is intended to stimulate scientific inquiry focused on innovative tobacco control policies. Applicants may propose projects in which the primary outcome of interest is on reducing tobacco use health disparities in vulnerable populations by utilizing tobacco prevention and control strategies. The long-term goal of this FOA is to reduce health disparities in health outcomes thereby reducing the excess disease burden of tobacco use within these groups. Applicants submitting applications related to health economics are encouraged to consult NOT-OD-16-025 to ensure that applications align with NIH mission priorities in health economics research. 

Unconventional Roles of Ethanol Metabolizing Enzymes, Metabolites, and Cofactors in Health and Disease (R01) - PA-15-058

Organization: NIAAA 

Posting Date: 12-08-2014 

Expiration Date: 01-08-2018 

Activity Code: R01 

Summary: The purpose of this FOA is to provide support for integrated, innovative research on the novel and unconventional contributions of ethanol metabolizing pathways, their metabolites, cofactors, and interactions with synergizing biological pathways in the development of alcohol- induced diseases and end organ injuries. It is anticipated that research supported under this FOA will generate data that leads to breakthroughs in identification and understanding of key cellular and molecular components in the initiation, progression and maintenance of the diverse medical disorders caused by excessive or long term alcohol consumption. This knowledge is critical for the diagnosis, treatment and management of vulnerable patient populations debilitated by the vast array of alcohol-induced pathologies and will enable clinicians to improve disease outcomes and, consequently, public health. 

Unconventional Roles of Ethanol Metabolizing Enzymes, Metabolites, and Cofactors in Health and Disease (R21) - PA-15-057

Organization: NIAAA 

Posting Date: 12-08-2014 

Expiration Date: 01-08-2018 

Activity Code: R21 

Summary: The purpose of this FOA is to provide support for integrated, innovative research on the novel and unconventional contributions of ethanol metabolizing pathways, their metabolites, cofactors, and interactions with synergizing biological pathways in the development of alcohol- induced diseases and end organ injuries. It is anticipated that research supported under this FOA will generate data that lead to breakthroughs in identification and understanding of key cellular and molecular components in the initiation, progression and maintenance of the diverse medical disorders caused by excessive or long term alcohol consumption. This knowledge is critical for the diagnosis, treatment and management of vulnerable patient populations debilitated by the vast array of alcohol-induced pathologies and will enable clinicians to improve disease outcomes and, consequently, public health. 

Underactive Bladder in Aging (R01) - PA-15-049

Organization: NIA 

Posting Date: 11-24-2014 

Expiration Date: 01-08-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications that propose basic, clinical, or translational research on underactive bladder (UAB) and its consequences in aging and in older persons. Applications should focus on the 1) biology, etiology and pathophysiology of UAB in animal models and/or older adults; 2) translation of basic/clinical research into clinical practice and health decision-making; 3) diagnosis, prevention, management and clinical outcomes of UAB in older adults; and/or 4) epidemiology and risk factors for the development of UAB with advancing age. Research supported by this initiative should enhance knowledge of UAB and its consequences in older adults and provide evidence-based guidance in the diagnosis, evaluation, and treatment of UAB in older persons. 

Underactive Bladder in Aging (R03) - PA-15-050

Organization: NIA 

Posting Date: 11-24-2014 

Expiration Date: 01-08-2018 

Activity Code: R03 

Summary: This Funding Opportunity Announcement (FOA) invites pilot/feasibility projects that propose basic, clinical, or translational research on underactive bladder (UAB) and its consequences in aging and in older persons. Applications should focus on the 1) biology, etiology and pathophysiology of UAB in animal models and/or older adults;2) translation of basic/clinical research into clinical practice and health decision-making; 3) diagnosis, prevention, management and clinical outcomes of UAB in older adults; and/or 4) epidemiology and risk factors for the development of UAB with advancing age. Pilot/feasibility research supported by this initiative should enhance knowledge of UAB and its consequences in older adults and provide evidence of feasibility of the diagnosis, evaluation, and/or treatment of UAB in older persons. 

Underactive Bladder in Aging (R21) - PA-15-051

Organization: NIA 

Posting Date: 11-24-2014 

Expiration Date: 01-08-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) invites applications that propose basic, clinical, or translational research on underactive bladder (UAB) and its consequences in aging and in older persons. Applications should focus on the 1) biology, etiology and pathophysiology of UAB in animal models and/or older adults;2) translation of basic/clinical research into clinical practice and health decision-making; 3) diagnosis, prevention, management and clinical outcomes of UAB in older adults; and/or 4) epidemiology and risk factors for the development of UAB with advancing age. The R21 mechanism is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. Research supported by this initiative should enhance knowledge of UAB and its consequences in older adults and provide evidence-based guidance in the diagnosis, evaluation, and treatment of UAB in older persons. 

Understanding Alzheimer's Disease in the Context of the Aging Brain (R01) - PAR-15-357

Organization: NIA 

Posting Date: 09-24-2015 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: The goal of this Funding Opportunity Announcement (FOA) is to establish the role and impact of brain aging in the development and progression of Alzheimers disease (AD).Comprehensive and integrative characterization of brain aging will help to define the mechanisms underlying the shift from healthy brain aging to the neuropathological processes of AD, knowledge that is critical for the design and development of effective interventions.Cross-disciplinary approaches to integrate findings on AD with research on the basic biology and neurobiology of aging are encouraged.  

Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development (R01 Clinical Trial Optional) - PA-18-032

Organization: NIDDK 

Posting Date: 11-01-2017 

Expiration Date: 05-08-2019 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications from institutions/organizations which propose to characterize or identify factors in early childhood (birth-24 months) that may increase or mitigate risk for obesity and/or excessive weight gain and/or to fill methodological research gaps relevant to the understanding of risk for development of obesity in children. Studies should propose research in children from birth to 24 months, although any proposed follow-up assessments, if applicable, may continue past this period. Studies may also assess factors relevant to families and/or caregivers of children from birth to 24 months. Applications should seek to fill unique research needs and involve expertise across disciplines as appropriate for the proposed research question. 

Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development (R01) - PA-16-169

Organization: NIDDK 

Posting Date: 04-06-2016 

Expiration Date: 05-08-2019 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications from institutions/organizations which propose to characterize or identify factors in early childhood (birth-24 months) that may increase or mitigate risk for obesity and/or excessive weight gain and/or to fill methodological research gaps relevant to the understanding of risk for development of obesity in children. Studies should propose research in children from birth to 24 months, although any proposed follow-up assessments, if applicable, may continue past this period. Studies may also assess factors relevant to families and/or caregivers of children from birth to 24 months. Applications should seek to fill unique research needs and involve expertise across disciplines as appropriate for the proposed research question. 

Understanding Processes of Recovery in the Treatment of Alcohol Use Disorder (R01) - PA-17-285

Organization: NIAAA 

Posting Date: 05-12-2017 

Expiration Date: 09-08-2020 

Activity Code: R01 

Summary: The purpose of this FOA is encourage applications that seek to examine processes of recovery and relapse in the treatment of Alcohol Use Disorders. Applications high in innovation and significance are highly encouraged that address the following potential topics: 1) Defining recovery; 2) Examining new and innovative methods to examine precipitants of relapse; 3) Understanding mechanisms of mutual help and recovery; 4) Evaluating recovery systems of care; and 5) Examining processes of extended treatment for AUD  

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