NIH Guide to Grants and Contracts

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Results: 1183 to 1207 of 1233

Display Results as:

Traceback Testing: Increasing Identification and Genetic Counseling of Mutation Carriers through Family-based Outreach (U01 Clinical Trial Optional) - PAR-18-616

Organization: NCI 

Posting Date: 02-01-2018 

Expiration Date: 07-06-2019 

Activity Code: U01 

Summary: The purpose of the Funding Opportunity Announcement (FOA) is to support research projects using a Traceback approach to genetic testing to identify unaffected individuals at increased risk for cancer in different clinical contexts and communities, including racially/ethnically diverse populations. 

Training Modules to Enhance the Rigor and Reproducibility of Biomedical Research (R25 Clinical Trial Not Allowed) - RFA-GM-18-002

Organization: NIGMS 

Posting Date: 02-01-2018 

Expiration Date: 06-30-2018 

Activity Code: R25 

Summary: The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs and foster a better understanding of biomedical, behavioral and clinical research and its implications. 

Transition to Independent Environmental Health Research (TIEHR) Career Transition Award (K01 Clinical Trial Not Allowed) - PAR-18-291

Organization: NIEHS 

Posting Date: 11-08-2017 

Expiration Date: 09-08-2019 

Activity Code: K01 

Summary: The Transitions to Independent Environmental Health (TIEHR) Career Award is a 3-year bridge scholar development program for newly independent faculty who intend to pursue research careers in environmental health sciences. At the conclusion of the career development period the candidates are expected to demonstrate they can successfully compete for research funding in the environmental health sciences. 

Transition to Independent Environmental Health Research (TIEHR) Career Transition Award (K01 Clinical Trial Required) - PAR-18-261

Organization: NIEHS 

Posting Date: 11-08-2017 

Expiration Date: 09-08-2019 

Activity Code: K01 

Summary: The Transitions to Independent Environmental Health (TIEHR) Career Award is a 3-year bridge scholar development program for newly independent faculty who intend to pursue research careers in environmental health sciences. At the conclusion of the career development period the candidates are expected to demonstrate they can successfully compete for research funding in the environmental health sciences. 

Translational Bioinformatics Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease (R01) - PAR-17-032

Organization: NIA 

Posting Date: 10-25-2016 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: This funding opportunity invites applications that integrate the use of computational approaches to identify individual drugs currently used for other conditions with potential to be efficacious in AD or AD-related dementias (as single drugs or as drug combinations) with proof-of-concept efficacy studies in cell-based models, animal models and/or humans.  

Translational Neural Devices (U44 - Clinical Trial Required) - RFA-NS-18-012

Organization: NINDS 

Posting Date: 11-08-2017 

Expiration Date: 10-22-2020 

Activity Code: U44 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from Small Business Concerns (SBCs) to pursue translational activities and small clinical studies to advance the development of therapeutic and diagnostic devices for disorders that affect the nervous or neuromuscular systems. The translational device activities, including translational bench and animal studies, are expected to lead to submission of an Investigational Device Exemption (IDE) to the U.S. Food and Drug Administration (FDA) or Institutional Review Board (IRB) application for a Non-Significant Risk (NSR) study. This cooperative agreement will also support the subsequent small clinical study to collect safety and effectiveness data required to support a marketing application or to inform final device design. 

Translational Neural Devices (UG3/UH3 - Clinical Trial Required) - RFA-NS-18-011

Organization: NINDS 

Posting Date: 11-08-2017 

Expiration Date: 10-22-2020 

Activity Code: UG3/UH3 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications to pursue translational activities and small clinical studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. The translational device activities, including translational bench and animal studies, are expected to lead to submission of an Investigational Device Exemption (IDE) to the U.S. Food and Drug Administration (FDA) or Institutional Review Board (IRB) application for a Non-Significant Risk (NSR) study. This cooperative agreement will also support the subsequent small clinical study to collect safety and effectiveness data required to support a marketing application or to inform final device design. 

Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R01 Clinical Trial Optional) - PAR-18-215

Organization: NICHD 

Posting Date: 11-28-2017 

Expiration Date: 04-04-2020 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is to encourage applications for translational and clinical research as well as clinical trials that will advance our knowledge about the underlying mechanisms of drug action, response, and safety in children at various developmental stages, and in women during pregnancy and lactation. The overall goals of the FOA are to improve the safety and effectiveness of current drugs for pediatric or obstetric patients, and to enhance the development of new drugs or a safer usage of the existing drugs for tailored therapies to meet emerging clinical needs for these special populations.  

Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R03) - PAR-17-188

Organization: NICHD 

Posting Date: 03-03-2017 

Expiration Date: 04-04-2020 

Activity Code: R03 

Summary: The purpose of this funding opportunity announcement (FOA) is to encourage applications for translational and clinical research as well as clinical trials that will advance our knowledge about the underlying mechanisms of drug action, response, and safety in children at various developmental stages, and in women during pregnancy and lactation. The overall goals of the FOA are to improve the safety and effectiveness of current drugs for pediatric or obstetric patients, and to enhance the development of new drugs or a safer usage of the existing drugs for tailored therapies to meet emerging clinical needs for these special populations.  

Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R21 Clinical Trial Optional) - PAR-18-214

Organization: NICHD 

Posting Date: 11-28-2017 

Expiration Date: 04-04-2020 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to encourage applications for translational and clinical research as well as clinical trials that will advance our knowledge about the underlying mechanisms of drug action, response, and safety in children at various developmental stages, and in women during pregnancy and lactation. The overall goals of the FOA are to improve the safety and effectiveness of current drugs for pediatric or obstetric patients, and to enhance the development of new drugs or a safer usage of the existing drugs for tailored therapies to meet emerging clinical needs for these special populations.  

Translational Studies on Adducts for Cancer Risk Identification and Prevention (U01) - PAR-15-307

Organization: NCI 

Posting Date: 07-24-2015 

Expiration Date: 07-12-2018 

Activity Code: U01 

Summary: This Funding Opportunity Announcement (FOA) encourages clinically-relevant translational/epidemiological research projects focused on the use of adducts to cellular macromolecules, as indicators of exposures to cancer risk factors in human populations and subgroups. The priority is on projects that will focus on adductomic approaches, i.e., address some aspects of the totality of adducts. The projects are expected to be based on comprehensive use of human biospecimens for which detailed medical data are available (e.g., biospecimens from the NCI-supported cohort studies). The main emphasis of this FOA is on advancing the area of cancer detection, cancer prevention, and assessing cancer risks in human populations and subgroups. Nonetheless, studies evaluating the potential roles of adducts in cancer etiology for gene-environment interaction research may also be appropriate provided that such projects are based on appropriate sets of human biospecimens (such as specimens from cohorts studies supported by NIH).  

Treating Diabetes Distress to Improve Glycemic Outcomes in Type 1 Diabetes (R01 Clinical Trial Required) - RFA-DK-17-028

Organization: NIDDK 

Posting Date: 02-14-2018 

Expiration Date: 07-11-2018 

Activity Code: R01 

Summary: This FOA seeks applications for clinical trials testing interventions targeting diabetes distress in individuals with T1D and/or their caregivers, with the goal of understanding whether lowering diabetes distress will improve glycemic control and quality of life. 

Trophoblast Differentiation and Function (R01) - PA-16-445

Organization: NICHD 

Posting Date: 09-23-2016 

Expiration Date: 01-08-2020 

Activity Code: R01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of trophoblast differentiation and function in relation to fertility and pregnancy, including the role of the immune system. It is anticipated that fundamental knowledge gained by this research will act as a solid foundation to hasten treatments for a number of placental-based pregnancy disorders, such as implantation failure, frequent pregnancy loss, preeclampsia, fetal growth restriction, and preterm birth.  

Trophoblast Differentiation and Function (R21 Clinical Trial Optional) - PA-18-047

Organization: NICHD 

Posting Date: 11-15-2017 

Expiration Date: 01-08-2020 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research in the area of trophoblast differentiation and function in relation to fertility and pregnancy, including the role of the immune system. It is anticipated that fundamental knowledge gained by this research will act as a solid foundation to hasten treatments for a number of placental-based pregnancy disorders, such as implantation failure, frequent pregnancy loss, preeclampsia, fetal growth restriction, and preterm birth.  

Typical and Atypical Patterns of Language and Literacy in Dual Language Learners (R01-Clinical Trial Optional) - PA-18-316

Organization: NIDCD 

Posting Date: 10-20-2017 

Expiration Date: 12-17-2020 

Activity Code: R01 

Summary: The purpose of this FOA is to support investigator-initiated R01 applications that will inform our understanding of the typical and atypical patterns of language and literacy development of dual language learners (DLLs) in the United States. Applicants are encouraged to take advantage of advances in the language sciences and related fields to identify and clarify specific cognitive, linguistic, neurobiological, and sociocultural factors associated with normal and impaired language and literacy acquisition in young DLL populations.  

Typical and Atypical Patterns of Language and Literacy in Dual Language Learners (R21-Clinical Trial Optional) - PA-18-328

Organization: NIDCD 

Posting Date: 10-20-2017 

Expiration Date: 12-17-2020 

Activity Code: R21 

Summary: The purpose of this FOA is to support investigator-initiated R21 applications that will inform our understanding of the typical and atypical patterns of language and literacy development of dual language learners (DLLs) in the United States. Applicants are encouraged to take advantage of advances in the language sciences and related fields to identify and clarify specific cognitive, linguistic, neurobiological, and sociocultural factors associated with normal and impaired language and literacy acquisition in young DLL populations.  

U.S. Tobacco Control Policies to Reduce Health Disparities (R01 Clinical Trial Optional) - PAR-18-675

Organization: NCI 

Posting Date: 02-21-2018 

Expiration Date: 06-16-2020 

Activity Code: R01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support observational or intervention research focused on reducing cancer health disparities in tobacco use in the United States. Specifically, this FOA is intended to stimulate scientific inquiry focused on innovative tobacco control policies. Applicants may propose projects in which the primary outcome of interest is on reducing tobacco use cancer health disparities in vulnerable populations by utilizing tobacco prevention and control strategies. The long-term goal of this FOA is to reduce cancer health disparities in health outcomes thereby reducing the excess disease burden of tobacco use within these groups. Applicants submitting applications related to health economics are encouraged to consult NOT-OD-16-025 to ensure that the research projects align with NIH mission priorities in health economics research. 

U.S. Tobacco Control Policies to Reduce Health Disparities (R21 Clinical Trial Optional) - PAR-18-674

Organization: NCI 

Posting Date: 02-21-2018 

Expiration Date: 06-16-2020 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to support observational or intervention research focused on reducing cancer health disparities in tobacco use in the United States. Specifically, this FOA is intended to stimulate scientific inquiry focused on innovative tobacco control policies. Applicants may propose projects in which the primary outcome of interest is on reducing tobacco use cancer health disparities in vulnerable populations by utilizing tobacco prevention and control strategies. The long-term goal of this FOA is to reduce cancer health disparities in health outcomes thereby reducing the excess disease burden of tobacco use within these groups. Applicants submitting applications related to health economics are encouraged to consult NOT-OD-16-025 to ensure that the research projects align with NIH mission priorities in health economics research. 

Underactive Bladder and Detrusor Activity in Aging (R01 Clinical Trial Optional) - PA-18-570

Organization: NIA 

Posting Date: 01-11-2018 

Expiration Date: 05-08-2021 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications that propose basic, clinical, or translational research on underactive bladder (UAB) and detrusor underactivity (DU) and its consequences in aging and in older persons. Applications should focus on the 1) biology, etiology and pathophysiology of DU or UAB in animal models and/or older adults; 2) translation of basic/clinical research into clinical practice and health decision-making; 3) diagnosis, prevention, management and clinical outcomes of UAB in older adults; and/or 4) epidemiology and risk factors for the development of DU/UAB with advancing age. Research supported by this initiative should enhance knowledge of DU/UAB and its consequences in older adults and provide evidence-based guidance in the diagnosis, evaluation, and treatment of DU/UAB in older persons. 

Underactive Bladder and Detrusor Activity in Aging (R03 Clinical Trial Optional) - PA-18-571

Organization: NIA 

Posting Date: 01-11-2018 

Expiration Date: 05-08-2021 

Activity Code: R03 

Summary: This Funding Opportunity Announcement (FOA) invites pilot/feasibility projects that propose basic, clinical, or translational research on underactive bladder (UAB) and detrusor underactivity (DU) and its consequences in aging and in older persons. Applications should focus on the 1) biology, etiology and pathophysiology of DU or UAB in animal models and/or older adults; 2) translation of basic/clinical research into clinical practice and health decision-making; 3) diagnosis, prevention, management and clinical outcomes of UAB in older adults; and/or 4) epidemiology and risk factors for the development of DU/UAB with advancing age. Pilot/feasibility research supported by this initiative should enhance knowledge of DU/UAB and its consequences in older adults and provide evidence-based guidance in the diagnosis, evaluation, and treatment of DU/UAB in older persons. 

Underactive Bladder and Detrusor Activity in Aging (R21 Clinical Trial Optional) - PA-18-572

Organization: NIA 

Posting Date: 01-11-2018 

Expiration Date: 05-08-2021 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) invites applications that propose basic, clinical, or translational research on underactive bladder (UAB) and detrusor underactivity (DU) and its consequences in aging and in older persons. Applications should focus on the 1) biology, etiology and pathophysiology of DU or UAB in animal models and/or older adults; 2) translation of basic/clinical research into clinical practice and health decision-making; 3) diagnosis, prevention, management and clinical outcomes of UAB in older adults; and/or 4) epidemiology and risk factors for the development of DU/UAB with advancing age. The R21 mechanism is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. Research supported by this initiative should enhance knowledge of DU/UAB and its consequences in older adults and provide evidence-based guidance in the diagnosis, evaluation, and treatment of DU/UAB in older persons. 

Undergraduate Summer Research Education in Kidney, Urologic, and Hematologic Diseases (R25 Clinical Trial Not Allowed) - RFA-DK-18-006

Organization: NIDDK 

Posting Date: 05-01-2018 

Expiration Date: 09-07-2018 

Activity Code: R25 

Summary: The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIDDK R25 program is to support educational activities that help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Research Experiences. This FOA solicits applications to establish summer research institutes for qualified undergraduates to participate in summer research experiences relevant to the mission of the Division of Kidney, Urologic and Hematologic Diseases/NIDDK (NIDDK/DKUH). 

Understanding Alzheimer's Disease in the Context of the Aging Brain (R01) - PAR-15-357

Organization: NIA 

Posting Date: 09-24-2015 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: The goal of this Funding Opportunity Announcement (FOA) is to establish the role and impact of brain aging in the development and progression of Alzheimers disease (AD).Comprehensive and integrative characterization of brain aging will help to define the mechanisms underlying the shift from healthy brain aging to the neuropathological processes of AD, knowledge that is critical for the design and development of effective interventions.Cross-disciplinary approaches to integrate findings on AD with research on the basic biology and neurobiology of aging are encouraged.  

Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development (R01 Clinical Trial Optional) - PA-18-032

Organization: NIDDK 

Posting Date: 11-01-2017 

Expiration Date: 05-08-2019 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications from institutions/organizations which propose to characterize or identify factors in early childhood (birth-24 months) that may increase or mitigate risk for obesity and/or excessive weight gain and/or to fill methodological research gaps relevant to the understanding of risk for development of obesity in children. Studies should propose research in children from birth to 24 months, although any proposed follow-up assessments, if applicable, may continue past this period. Studies may also assess factors relevant to families and/or caregivers of children from birth to 24 months. Applications should seek to fill unique research needs and involve expertise across disciplines as appropriate for the proposed research question. 

Understanding Processes of Recovery in the Treatment of Alcohol Use Disorder (R01 - Clinical Trial Optional) - PA-18-619

Organization: NIAAA 

Posting Date: 02-02-2018 

Expiration Date: 05-08-2021 

Activity Code: R01 

Summary: The purpose of this FOA is encourage applications that seek to examine processes of recovery and relapse in the treatment of Alcohol Use Disorders. Applications high in innovation and significance are highly encouraged that address the following potential topics: 1) defining recovery; 2) Examining new and innovative methods to examine precipitants of relapse; 3) Understanding mechanisms of mutual help and recovery; 4) Evaluating recovery systems of care; and 5) Examining processes of extended treatment for AUD. 

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