NIH Guide to Grants and Contracts

The NIH Guide for Grants and Contracts is our official publication for NIH grant policies, guidelines and funding opportunities. We publish daily, and issue a table of contents weekly. Learn more about the NIH Guide and subscribe today!

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Results: 26 to 50 of 1419

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NIDDK Research Education Program Grants for Curriculum Development (R25) - PAR-15-138

Organization: NIDDK 

Posting Date: 03-13-2015 

Expiration Date: 05-08-2018 

Activity Code: R25 

Summary: The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIDDK Research Education R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish this goal, this FOA will support creative educational activities that propose the development of novel curricula or methods in the research areas relevant to the NIDDK. 

International Research Collaboration on Drug Abuse and Addiction Research (R03) - PA-15-141

Organization: NIDA 

Posting Date: 03-17-2015 

Expiration Date: 01-25-2018 

Activity Code: R03 

Summary: This Funding Opportunity Announcement (FOA) encourages collaborative research applications on drug abuse and addiction that take advantage of special opportunities that exist outside the United States. Special opportunities include access to unusual talent, resources, populations, or environmental conditions in other countries that will speed scientific discovery. Projects should have relevance to the mission of NIDA and where feasible should address NIDAs international scientific priority areas(http://www.drugabuse.gov/international/research-priorities). While the priorities will change from year to year, in FY15 priority areas include: linkages between HIV/AIDS and drug abuse; prevention, initiation, and treatment of nicotine and tobacco use (especially among vulnerable populations such as children, adolescents, pregnant women, and those with co-morbid disorders); the neuroscience of marijuana and cannabinoids; and the effect of changes in laws and policies on marijuana and its impact. The NIH R03 activity code supports discrete, well-defined projects that realistically can be completed in two years and that require limited levels of funding. The R03 activity code supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. 

International Research Collaboration on Drug Abuse and Addiction Research (R21) - PA-15-143

Organization: NIDA 

Posting Date: 03-17-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages collaborative research applications on drug abuse and addiction that take advantage of special opportunities that exist outside the United States. Special opportunities include access to unusual talent, resources, populations, or environmental conditions in other countries that will speed scientific discovery. Projects should have relevance to the mission of NIDA and where feasible should address NIDAs international scientific priority areas (http://www.drugabuse.gov/international/research-priorities). While the priorities will change from year to year, in FY15 priority areas include: linkages between HIV/AIDS and drug abuse; prevention, initiation, and treatment of nicotine and tobacco use (especially among vulnerable populations such as children, adolescents, pregnant women, and those with co-morbid disorders); the neuroscience of marijuana and cannabinoids; and the effect of changes in laws and policies on marijuana and its impact. The R21 activity code is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. Projects of limited cost or scope that use widely accepted approaches and methods within well-established fields are better suited for the R03 small grant activity code. 

AHRQ Small Research Grant Program (R03) - PA-15-147

Organization: AHRQ 

Posting Date: 03-19-2015 

Expiration Date: 07-17-2018 

Activity Code: R03 

Summary: This FOA encourages Small Research Grant (R03) applications, and expresses AHRQ priority areas of interest for ongoing small research projects. The R03 grant mechanism supports different types of health services research projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. 

Alcohol Impairment of Immune Function, Host Defense and Tissue Homeostasis (R01) - PA-15-159

Organization: NIAAA 

Posting Date: 03-26-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications from researchers with broad expertise to study the consequences of alcohol consumption on immune function with a goal toward improving the outcome of patients who abuse alcohol.  

Pilot and Feasibility Clinical Research Grants in Urologic Disorders (R21) - PAR-15-162

Organization: NIDDK 

Posting Date: 03-27-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) is to support Exploratory/Developmental Research Grants (R21) that propose small scale or pilot and feasibility clinical and translational research studies, including epidemiological studies or clinical trials related to urologic disorders research. Studies should address important clinical and translational questions that are potentially of high clinical and public health impact. It is anticipated that some projects supported by these grants may lead to full-scale clinical studies including diagnostic strategies, epidemiological studies, or randomized clinical trials of prevention, diagnosis or treatment of urologic disorders. 

Pilot and Feasibility Clinical Research Grants in Kidney Diseases (R21) - PAR-15-161

Organization: NIDDK 

Posting Date: 03-27-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) is to support Exploratory/Developmental Research Grants (R21) that propose small scale or pilot and feasibility clinical and translational research studies, including epidemiological studies or clinical trials related to kidney disease research. Studies should address important clinical and translational questions and are potentially of high clinical and public health impact. It is anticipated that some projects supported by these grants may lead to full-scale clinical studies including diagnostic strategies, epidemiological studies, or randomized clinical trials of diagnosis, prevention, or treatment of kidney diseases. 

Exploratory/Developmental Clinical Research Grants in Obesity (R21) - PA-15-163

Organization: NIDDK 

Posting Date: 03-27-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages research grant applications from institutions/organizations that propose to conduct exploratory/developmental clinical studies that will accelerate the development of effective interventions for prevention or treatment of overweight or obesity in adults and/or children. Exploratory epidemiological research with a goal of informing translational/clinical research will also be supported within this program.  

New Directions in Hematology Research (SHINE-II) (R01) - PAS-15-168

Organization: NIDDK 

Posting Date: 04-01-2015 

Expiration Date: 05-08-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) is intended to promote innovative research initiatives that explore high impact, new directions of inquiry relevant to the hematology research mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).NIDDK invites investigator-initiated grant applications for basic or pre-clinical, proof of principle research projects that are tightly focused and directed at validating novel concepts and approaches that promise to open up new pathways for discovery.Research applications submitted under this FOA should be more limited in scope (a single central aim) and duration (1-3 years) than typical R01 grant applications.  

Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21) - PA-15-169

Organization: NIDDK 

Posting Date: 04-01-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses of existing data sets relevant to diabetes and selected endocrine and metabolic diseases including thyroid, parathyroid and Cushings diseases and acromegaly; and genetic metabolic disease including cystic fibrosis, lysosomal storage diseases, and disorders of the urea cycle, amino acid metabolism and metal transport where the focus is on peripheral metabolism or organ function; obesity, liver diseases, alimentary GI tract diseases and nutrition; kidney, urologic, and hematologic diseases. The goal of this program is to facilitate research that explores innovative hypotheses through the use of existing data sets. 

Diet and Physical Activity Assessment Methodology (R21) - PAR-15-171

Organization: NIDDK 

Posting Date: 04-02-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages innovative research to enhance the quality of measurements of dietary intake and physical activity. Applications submitted to this FOA may include development of: novel assessment approaches; better methods to evaluate instruments; assessment tools for culturally diverse populations or various age groups, including children and older adults; improved technology or applications of existing technology; statistical methods/modeling to improve assessment and/or to correct for measurement errors or biases; methods to investigate the multidimensionality of diet and physical activity behavior through pattern analysis; or integrated measurement of diet and physical activity along with the environmental context of such behaviors. 

Collaborative Innovation Award, Clinical and Translational Science Award (CTSA) Program (U01) - PAR-15-172

Organization: NCATS 

Posting Date: 04-02-2015 

Expiration Date: 01-25-2018 

Activity Code: U01 

Summary: The purpose of this funding opportunity announcement (FOA) is to invite applications to stimulate innovative collaborative research in the NCATS Clinical and Translational Science Award (CTSA) consortium. 

Alzheimer's Drug-Development Program (U01) - PAR-15-174

Organization: NIA 

Posting Date: 04-02-2015 

Expiration Date: 01-25-2018 

Activity Code: U01 

Summary: The goal of this Funding Opportunity Announcement (FOA) is to provide funding support for the pre-clinical and early stage clinical (Phase I) development ofsmall-molecule and biologic therapeutic agents that prevent Alzheimer's disease (AD), slow its progression or treat its cognitive and behavioral symptoms.Participants in this program will receive funding for therapy development activities such as medicinal chemistry, pharmacokinetics (PK), Absorption, Distribution, Metabolism, Excretion, Toxicology (ADMET), efficacy in animal models, formulation development, chemical synthesis under Good Manufacturing Practices (GMP), Investigational New Drug (IND) enabling studies and initial Phase I clinical testing. This program does not support research on basic mechanisms of disease, development of biomarkers, devices, non-pharmacological interventions (e.g., exercise, diet, cognitive training), repurposed drugs and combinations therapies or, discovery activities such as high throughput screening and hit optimization. 

Phenotypic and Functional Studies on FOXO3 Human Longevity Variants to Inform Potential Therapeutic Target Identification Research (R01) - PAR-15-175

Organization: NIA 

Posting Date: 04-03-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: The focus of this Funding Opportunity Announcement (FOA) is on in vivo human studies, and in vitro studies on human cells or tissues, aimed at potential identification of therapeutic targets or and/or testing of interventions for healthy aging. Potential therapeutic targets include FOXO3 itself and upstream and downstream regulators in pathways mediated by FOXO3. The range of research areas of interest in this FOA includes studies that: 1) examine in vivo phenotypic effects of human FOXO3 variants, and/or 2) elucidate effects of these variants on cellular functions and the pathways that mediate them, and/or 3) identify and evaluate candidate therapeutic targets (e.g., target validation studies, testing of candidate compounds) for potential interventions based on FOXO3 functional pathways.  

Pilot and Feasibility Studies in Preparation for Drug and Alcohol Abuse Prevention Trials (R34) - PA-15-177

Organization: NIDA 

Posting Date: 04-07-2015 

Expiration Date: 01-25-2018 

Activity Code: R34 

Summary: This Funding Opportunity Announcement (FOA) for R34 applications seeks to support: (a) pilot and/or feasibility testing of innovative new, revised, or adapted prevention intervention approaches to prevent or delay the initiation and onset of drug and alcohol use, the progression to problem use or alcohol and other substance use disorder, reduce drinking and driving and deaths related to impaired driving andthe drug- or alcohol-related acquisition or transmission of HIV infection and viral hepatitis among diverse populations and settings; and (b) pre-trial feasibility testing for prevention services and systems research. It is expected that research conducted via this R34 mechanism will consist of early stage efficacy, effectiveness or services research that will provide intervention pilot and/or feasibility data that is a pre-requisite for preparing and submitting subsequent applications for larger scale drug or alcohol abuse prevention and/or drug- or alcohol-related HIV prevention intervention studies. This R34 FOA does not support applications for which the sole focus is development of intervention protocols, manuals, or the standardization of protocols; rather, any development work must be imbedded within a pilot/feasibility study.Of particular interest are prevention interventions targeting the healthcare system.  

Understanding and Improving Diagnostic Safety in Ambulatory Care: Strategies and Interventions (R18) - PA-15-179

Organization: AHRQ 

Posting Date: 04-08-2015 

Expiration Date: 09-26-2018 

Activity Code: R18 

Summary: Despite the growing interest and rapid pace of recent achievements, not much is known with a high degree of confidence about the strategies and interventions that might reduce diagnostic failures and patient harms or enhance the resilience and safety of diagnostic work. This Funding Opportunity Announcement (FOA) solicits applications from research institutions and their investigators to conduct Health Services Research Demonstration and Dissemination Projects (R18) to evaluate strategies and interventions for reducing diagnostic failures and patient harms, including approaches that enable organizations, providers and patients to better anticipate emerging diagnostic risk before failure and harm occurs.  

Understanding and Improving Diagnostic Safety in Ambulatory Care: Incidence and Contributing Factors (R01) - PA-15-180

Organization: AHRQ 

Posting Date: 04-08-2015 

Expiration Date: 11-06-2018 

Activity Code: R01 

Summary: Despite the growing interest and rapid pace of recent achievements, not much is known with a high degree of confidence about the prevalence of diagnostic failure in its various manifestations. This Funding Opportunity Announcement (FOA) solicits applications from research institutions and their investigators to conduct Health Services Research Projects (R01) to gain a better understanding of the complexity and incidence of diagnostic failure and its associated costs and harms. 

Mental Health Research Dissertation Grant to Enhance Workforce Diversity (R36) - PAR-15-181

Organization: NIMH 

Posting Date: 04-08-2015 

Expiration Date: 05-08-2018 

Activity Code: R36 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to enhance the diversity of the mental health research workforce by providing dissertation awards in all research areas within the strategic priorities of the NIMH to individuals from diverse backgrounds underrepresented in biomedical, behavioral, clinical and social sciences research. This two-year award supports the completion of the doctoral research project. 

Summer Research Education Experience Programs (R25) - PAR-15-184

Organization: NIAAA 

Posting Date: 04-16-2015 

Expiration Date: 05-24-2018 

Activity Code: R25 

Summary: The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that foster a better understanding of biomedical, behavioral and clinical research and its implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Research Experiences for high school, undergraduate and science teachers during the summer academic break.  

Novel Tools and Devices for Animal Research Facilities and to Support the Care of Animal Models (R43/R44) - PAR-15-186

Organization: ORIP 

Posting Date: 04-16-2015 

Expiration Date: 09-06-2018 

Activity Code: R43/R44 

Summary: Research (SBIR) projects to develop novel tools and devices to improve handling of laboratory animals, to ease the management of animal facilities, and to enhance experiments which use animal models. The intent is to facilitate the development and implementation of tools and devices to directly benefit the welfare of research animals, and to advance equipment to improve infrastructure and environmental conditions of animal facilities that support biomedical and bio-behavioral research.  

Development of Novel Tools and Devices to Support the Care of Animal Models and Animal Care Research Facilities (R41/R42) - PAR-15-185

Organization: ORIP 

Posting Date: 04-16-2015 

Expiration Date: 09-06-2018 

Activity Code: R41/R42 

Summary: This funding opportunity announcement (FOA) encourages applications from small business concerns (SBCs) for Small Business Technology Transfer (STTR) projects to develop novel tools and devices to improve handling of laboratory animals, to ease the management of animal facilities, and to enhance experiments which use animal models. The intent is to facilitate the development and implementation of tools and devices to directly benefit the welfare of research animals, and to advance equipment to improve infrastructure and environmental conditions of animal facilities that support biomedical and bio-behavioral research.  

Enhancing Regulatory Science for the Risk Based Assessment of Emerging Manufacturing Technologies (U01) - PAR-15-187

Organization: FDA 

Posting Date: 04-17-2015 

Expiration Date: 05-01-2019 

Activity Code: U01 

Summary: The goal of this program is to support the advancement of regulatory science that can facilitate the implementation and the assessment of emerging manufacturing technology in the pharmaceutical sector. Emerging manufacturing technology can be viewed as a technology that has the potential to modernize the pharmaceutical manufacturing body of knowledge to support more robust, predictable, and/or cost-effective processes and with which the FDA has limited review or inspection experiences, due to its relative novelty. Examples of such elements include an innovative or novel: (1) product manufacturing technology, such as the dosage form; (2) manufacturing process (e.g., design, scale-up, and/or commercial scale); and/or (3) testing technology.  

T2 Translational Research: Research Leading to New Health Care Practices, Community Programs and Policies Affecting Older Persons (R21) - PAR-15-191

Organization: NIA 

Posting Date: 04-28-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This funding opportunity announcement (FOA) encourages exploratory/developmental research projects on translational research (T2) directed towards development of health care practices, community programs and policies, including monitoring and quality improvement for pharmacological and non-pharmacological approaches for preventing and treating key health issues affecting the elderly. For the purposes of this FOA, T2 translational research on aging is defined as research to gather information needed to develop or evaluate methods of translating results from clinical studies into everyday clinical practice and health decision making (e.g., adapting an efficacious intervention for application in clinical practice and evaluating its effectiveness in different clinical settings). Methods for T2 translational research include but are not limited to intervention studies, systematic reviews, meta-analysis, outcomes research and implementation research. 

T1 Translational Research: Novel Interventions for Prevention and Treatment of Age-related Conditions (R21) - PAR-15-190

Organization: NIA 

Posting Date: 04-28-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This funding opportunity announcement (FOA) encourages exploratory/developmental research projects to accelerate the pace of development of novel therapeutics involving biologics, pharmacological and non-pharmacological approaches for preventing and treating key health issues affecting the elderly. For the purposes of this FOA, T1 translational research on aging is defined as the application of basic and clinical biomedical findings towards the development of new strategies for prevention and treatment of age-related pathologies.  

Immune System Plasticity in the Pathogenesis and Treatment of Complex Dental, Oral, and Craniofacial Diseases (R21) - PAR-15-193

Organization: NIDCR 

Posting Date: 04-28-2015 

Expiration Date: 09-08-2018 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage research projects to elucidate the role of immune system plasticity in health and in the pathogenesis of dental, oral, and craniofacial diseases. The goal is to advance knowledge of the immunological basis of dental, oral, and craniofacial diseases, and to develop tools and technologies for precise modulation of the immune system to restore or maintain health. The expectation is that new knowledge derived from this research will facilitate development of novel immunomodulatory therapies to prevent disease onset or reverse disease progression. 

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