NIH Guide to Grants and Contracts

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Results: 26 to 50 of 1250

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Exploiting RNA as a Target for HIV Interventions (R21) - PA-15-272

Organization: NIAID 

Posting Date: 06-05-2015 

Expiration Date: 05-08-2018 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to: (1) investigate the role of viral and cellular long non-coding RNAs (lncRNAs) in the regulation of HIV replication, pathogenesis, latency, immunity, and gene expression; (2) exploit lncRNAs for the development of novel HIV interventions; and (3) exploit advances in RNA structural biology to identify novel targets for HIV intervention and functional cure.  

Strategies to Increase Delivery of Guideline-Based Care to Populations with Health Disparities (R01) - PAR-15-279

Organization: NHLBI 

Posting Date: 06-18-2015 

Expiration Date: 06-22-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications to conduct innovative and feasible studies to test strategies to accelerate the adoption of guideline-based recommendations into clinical practice among populations with health disparities. Applications that propose strategies with a focus on providers who care for clinical populations with excess burden of cardiovascular, lung, blood, and sleep diseases and disorders, in concert with the health care delivery systems in which they practice, are strongly encouraged. Applications that test systems, infrastructures, and strategies to implement guideline-based care for NHLBI disorders in clinical care settings are also of high programmatic interest.  

Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01) - PAR-15-297

Organization: NCI 

Posting Date: 07-14-2015 

Expiration Date: 08-16-2018 

Activity Code: U01 

Summary: This Funding Opportunity Announcement (FOA) encourages the submission of applications that propose to advance research in cancer etiology and early detection biomarkers, utilizing the advantages of the unique biorepository resources of the NCI-sponsored Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial. The PLCO Biorepository offers high-quality, prospectively collected, serial pre-diagnostic blood samples from the PLCO screened arm participants, and a onetime collection of buccal cells from the control arm participants. Available data associated with the biospecimens includes demographic, diet, lifestyle, smoking, screening results, and clinical data. This FOA supports a wide range of cancer research including, but not limited to, biochemical and genetic analyses of cancer risk, as well as discovery and validation of early detection biomarkers. The proposed research project must involve use of PLCO biospecimens; additionally, it should also take advantage of the unique characteristics of the PLCO biospecimens. Research projects that do not involve the use of PLCO biospecimens will not be supported under this FOA. 

Establishing Outcome Measures for Clinical Studies of Oral and Craniofacial Diseases and Conditions (R21) - PAR-15-298

Organization: NIDCR 

Posting Date: 07-17-2015 

Expiration Date: 09-08-2018 

Activity Code: R21 

Summary: The goal of this funding opportunity announcement is to support the development of well-founded outcome measures, including establishing their reliability and validity, for clinical studies of those with oral and craniofacial diseases and conditions. 

Establishing Outcome Measures for Clinical Studies of Oral and Craniofacial Diseases and Conditions (R01) - PAR-15-302

Organization: NIDCR 

Posting Date: 07-17-2015 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: The goal of this funding opportunity announcement is to support the development of well-founded outcome measures, including establishing their reliability and validity, for clinical studies of those with oral and craniofacial diseases and conditions. 

Occupational Safety and Health Education and Research Centers (T42) - PAR-15-303

Organization: CDC 

Posting Date: 07-21-2015 

Expiration Date: 10-21-2019 

Activity Code: T42 

Summary: The National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC), invites grant applications for funding Education and Research Centers (ERCs) that are focused on occupational safety and health training, research training, education and outreach. NIOSH is mandated to provide an adequate supply of qualified personnel to carry out the purposes of the Occupational Safety and Health Act, and the ERCs are one of the principal means for meeting this mandate. ERCs are academic institutions that provide high-quality interdisciplinary graduate training, research training, continuing education, and outreach in the core occupational safety and health disciplines of industrial hygiene (IH), occupational health nursing (OHN), occupational medicine residency (OMR), and occupational safety (OS), as well as closely related allied disciplines. Research and research training are integral components of ERCs, with ERC faculty and NIOSH trainees conducting research on issues related to the NIOSH National Occupational Research Agenda (NORA). The ERCs also serve as regional resources for industry, labor, government, and the public. 

Translational Studies on Adducts for Cancer Risk Identification and Prevention (U01) - PAR-15-307

Organization: NCI 

Posting Date: 07-24-2015 

Expiration Date: 07-12-2018 

Activity Code: U01 

Summary: This Funding Opportunity Announcement (FOA) encourages clinically-relevant translational/epidemiological research projects focused on the use of adducts to cellular macromolecules, as indicators of exposures to cancer risk factors in human populations and subgroups. The priority is on projects that will focus on adductomic approaches, i.e., address some aspects of the totality of adducts. The projects are expected to be based on comprehensive use of human biospecimens for which detailed medical data are available (e.g., biospecimens from the NCI-supported cohort studies). The main emphasis of this FOA is on advancing the area of cancer detection, cancer prevention, and assessing cancer risks in human populations and subgroups. Nonetheless, studies evaluating the potential roles of adducts in cancer etiology for gene-environment interaction research may also be appropriate provided that such projects are based on appropriate sets of human biospecimens (such as specimens from cohorts studies supported by NIH).  

Research to Advance Vaccine Safety (R01) - PA-15-312

Organization: NIAID 

Posting Date: 07-28-2015 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is to support research that will contribute to the overall understanding of vaccine safety. This research opportunity encourages studies that address scientific areas potentially relevant to vaccine safety such as 1) physiological and immunological responses to vaccines and vaccine components, 2) how genetic variations affect immune/physiological responses that may impact vaccine safety, 3) identification of risk factors and biological markers that may be used to assess whether there is a relationship between certain diseases or disorders and licensed vaccines, 4) creation/evaluation of statistical methodologies for analyzing data on vaccine safety, including data available from existing data sources such as passive reporting systems or healthcare databases, or 5) the application of genomic/molecular technologies and systems biology approaches to evaluate vaccine safety. This FOA aligns with the research goals and objectives outlined in the U.S. National Vaccine Plan). 

Research to Advance Vaccine Safety (R21) - PA-15-313

Organization: NIAID 

Posting Date: 07-28-2015 

Expiration Date: 09-08-2018 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to support research that will contribute to the overall understanding of vaccine safety. This research opportunity encourages studies that address scientific areas potentially relevant to vaccine safety such as 1) physiological and immunological responses to vaccines and vaccine components, 2) how genetic variations affect immune/physiological responses that may impact vaccine safety, 3) identification of risk factors and biological markers that may be used to assess whether there is a relationship between certain diseases or disorders and licensed vaccines, 4) creation/evaluation of statistical methodologies for analyzing data on vaccine safety, including data available from existing data sources such as passive reporting systems or healthcare databases, or 5) the application of genomic/molecular technologies and systems biology approaches to evaluate vaccine safety. This FOA aligns with the research goals and objectives outlined in the U.S. National Vaccine Plan). 

Discovery of Genetic Basis of Monogenic Heart, Lung, Blood, and Sleep Disorders (X01) - PAR-15-314

Organization: NHLBI 

Posting Date: 07-29-2015 

Expiration Date: 06-16-2018 

Activity Code: X01 

Summary: This Funding Opportunity Announcement (FOA) invites applications to use the genome-wide sequencing capacity of the Centers for Mendelian Genomics to carry out studies of the genetic basis of Mendelian or monogenic disorders that significantly affect heart, lung, blood, and sleep (HLBS) systems. 

AHRQ Grants for Health Services Research Dissertation Program (R36) - PA-15-318

Organization: AHRQ 

Posting Date: 08-04-2015 

Expiration Date: 11-02-2018 

Activity Code: R36 

Summary: This announcement represents the continuation of an AHRQ program that provides support to individuals who are conducting research undertaken as part of an accredited academic program to qualify for a research doctorate degree.  

Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21) - PAR-15-334

Organization: NCI 

Posting Date: 08-18-2015 

Expiration Date: 11-21-2018 

Activity Code: R21 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to invite exploratory/developmental research grant (R21) applications for the development of innovative methods and algorithms in biomedical computing, informatics, and data science addressing priority needs across the cancer research continuum, including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities.As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA encourages applications focused on the development of novel computational, mathematical, and statistical algorithms and methods that can considerably improve acquisition, management, analysis, and dissemination of relevant data and/or knowledge. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the proposed informatics method or algorithm must have a clear rationale on why it is novel and how it will benefit the cancer research field. Potential applicants who are interested in more downstream tool development, from prototyping to hardening and adaptation, should consult the other companion FOAs listed above. 

Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01) - PAR-15-332

Organization: NCI 

Posting Date: 08-18-2015 

Expiration Date: 11-21-2018 

Activity Code: U01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U01) applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this FOA focuses on early-stage development from prototyping to hardening and adaptation. Early-stage development is defined for the purpose of this FOA as the initial development or the significant modification of existing tools for new applications. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from users and collaborators throughout the development process should be included.  

Advanced Development of Informatics Technologies for Cancer Research and Management (U24) - PAR-15-331

Organization: NCI 

Posting Date: 08-18-2015 

Expiration Date: 11-21-2018 

Activity Code: U24 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U24) applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum, including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA focuses on emerging informatics technology, defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research.In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from users and collaborators throughout the development process should be included. Potential applicants who are interested in early-stage development or informatics resource sustainment should consult companion FOAs listed above.  

Sustained Support for Informatics Resources for Cancer Research and Management (U24) - PAR-15-333

Organization: NCI 

Posting Date: 08-18-2015 

Expiration Date: 11-21-2018 

Activity Code: U24 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement (U24) applications for the continued development and sustainment of high-value informatics research resources to serve current and emerging needs across the cancer research continuum including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCIs Informatics Technology for Cancer Research (ITCR) Program, this FOA focuses on supporting activities necessary for improved user experience and availability of existing, widely-adopted informatics tools and resources.This is in contrast to early-stage and advanced development efforts to generate these tools and resources that are supported by companion ITCR FOAs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the proposed sustainment plan must provide clear justifications for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field.In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting collaboration and/or deep engagement between the resource and the targeted research community should be described.  

Imaging Diagnostics of Dental Diseases and Conditions (Caries, Periodontal Disease, Cracked Teeth, and Pulp Vitality) (R41/R42) - PA-15-336

Organization: NIDCR 

Posting Date: 08-20-2015 

Expiration Date: 09-08-2018 

Activity Code: R41/R42 

Summary: The intent of this STTR initiative reissue is to accelerate the advanced development and clinical implementation of reliable, reproducible, highly specific and sensitive imaging diagnostic devices for dental caries, periodontal disease, cracked teeth, and pulp vitality. These new devices must demonstrate superior specificity and sensitivity compared with current diagnostic methods, such as the visual/tactile/radiographic examination for detection of caries, while not increasing health risks for patients. Approaches that could be explored include, but are not limited to: optical coherence tomography (OCT) with or without Raman spectroscopy, MRI image analysis, electrical conductivity measurement (ECM), quantitative laser fluorescence (QLF), alternating current impedance spectroscopy, multi-photon imaging, infrared thermography, infrared fluorescence (IR), ultrasound, and terahertz imaging.The development of novel modalities is also encouraged. 

Imaging Diagnostics of Dental Diseases and Conditions (Caries, Periodontal Disease, Cracked Teeth, and Pulp Vitality) (R43/R44) - PA-15-335

Organization: NIDCR 

Posting Date: 08-20-2015 

Expiration Date: 09-08-2018 

Activity Code: R43/R44 

Summary: The intent of this SBIR initiative reissue is to accelerate the advanced development and clinical implementation of reliable, reproducible, highly specific and sensitive imaging diagnostic devices for dental caries, periodontal disease, cracked teeth, and pulp vitality. These new devices must demonstrate superior specificity and sensitivity compared with current diagnostic methods, such as the visual/tactile/radiographic examination for detection of caries, while not increasing health risks for patients. Approaches that could be explored include, but are not limited to: optical coherence tomography (OCT) with or without Raman spectroscopy, MRI image analysis, electrical conductivity measurement (ECM), quantitative laser fluorescence (QLF), alternating current impedance spectroscopy, multi-photon imaging, infrared thermography, infrared fluorescence (IR), ultrasound, and terahertz imaging.The development of novel modalities is also encouraged. 

NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) - PAR-15-344

Organization: NIDCR 

Posting Date: 09-09-2015 

Expiration Date: 09-08-2018 

Activity Code: R03 

Summary: The goal of this funding opportunity announcement is to support meritorious research projects that involve secondary data analyses of existing oral or craniofacial database resources, or to develop needed statistical methodology for analyzing oral and craniofacial data using existing oral or craniofacial databases. The R03 grant mechanism supports research limited in time and amount for studies in categorical program areas.  

Time-Sensitive Obesity Policy and Program Evaluation (R01) - PAR-15-346

Organization: NIDDK 

Posting Date: 09-17-2015 

Expiration Date: 09-14-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) establishes an accelerated review/award process to support time-sensitive research to evaluate a new policy or program that is likely to influence obesity related behaviors (e.g., dietary intake, physical activity, or sedentary behavior) and/or weight outcomes in an effort to prevent or reduce obesity.This FOA is intended to support research where opportunities for empirical study are, by their very nature, only available through expedited review and funding.All applications to this FOA must demonstrate that the evaluation of an obesity related policy and /or program offers an uncommon and scientifically compelling research opportunity that will only be available if the research is initiated with minimum delay. For these reasons, applications in response to this time-sensitive FOA are not eligible for resubmission. It is intended that eligible applications selected for funding will be awarded within 4 months of the application due date. However, administrative requirements and other unforeseen circumstances may delay issuance dates beyond that timeline.  

Health Disparities and Alzheimer's Disease (R01) - PAR-15-349

Organization: NIA 

Posting Date: 09-17-2015 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: This FOA invites applications proposing to study health disparities in Alzheimers disease (AD) and related disorders. Health-disparities research related to AD should include the study of biological, behavioral, sociocultural, and environmental factors that influence population level health differences. Research approaches of interest include 1) improving recruitment and retention of populations underrepresented in AD research, 2) identifying priority factors or locating pathways and mechanisms that create and sustain AD health disparities, 3) addressing the challenges faced by informal/family caregivers from diverse racial, ethnic and socioeconomic backgrounds that are associated with the growing population of individuals with Alzheimers Disease, and 4) understanding the disparities in access to and utilization of formal long-term supports and services for those with dementia. 

Emerging Directions for Addressing Health Disparities in Alzheimer's Disease (R03) - PAR-15-350

Organization: NIA 

Posting Date: 09-17-2015 

Expiration Date: 09-08-2018 

Activity Code: R03 

Summary: This FOA invites applications proposing to study health disparities in Alzheimers disease (AD) and related disorders. Health disparities research related to AD should include the study of biological, behavioral, sociocultural and environmental factors that influence population level health differences. Research approaches of interest include 1) improving recruitment and retention of populations underrepresented in AD research, 2) identifying priority factors or locating pathways and mechanisms that create and sustain AD health disparities, 3) addressing the challenges faced by informal/family caregivers from diverse racial, ethnic and socioeconomic backgrounds that are associated with the growing population of individuals with Alzheimers Disease, and 4) understanding the disparities in access to and utilization of formal long-term supports and services for those with dementia. 

Occupational Safety and Health Training Project Grants (T03) - PAR-15-352

Organization: NIOSH 

Posting Date: 09-21-2015 

Expiration Date: 11-04-2019 

Activity Code: T03 

Summary: The National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention (CDC), invites grant applications for Training Project Grants (TPGs) that are focused on occupational safety and health training. NIOSH is mandated to provide an adequate supply of qualified personnel to carry out the purposes of the Occupational Safety and Health Act, and the TPGs are one of the principal means for meeting this mandate. The majority of TPGs are in academic institutions that provide high quality training in the core occupational safety and health disciplines of industrial hygiene (IH), occupational health nursing (OHN), occupational medicine residency (OMR), occupational safety (OS), as well as closely related allied disciplines. NIOSH also funds non-academic programs to meet specific training needs of targeted populations including firefighters, commercial fishermen and occupational health and safety interns. 

Major Opportunities for Research in Epidemiology of Alzheimer's Disease and Cognitive Resilience (R01) - PAR-15-356

Organization: NIA 

Posting Date: 09-24-2015 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) encourages investigator-initiated applications addressing the epidemiology of Alzheimers disease (AD) as well as protective factors for cognitive health and resilience. All projects in cognitive epidemiology and genetics/genomics relevant to AD are welcome. NIA especially encourages projects or revisions to projects that propose: augmenting existing longitudinal cohort studies; enabling precision medicine for AD; enhancing the power of multi-ethnic cohort studies; exploring trends in the risk of AD and their explanation via putative risk and protective factors; collecting and sequencing DNA samples from well-characterized cases and controls; electronic archiving of cohort studies; harmonizing complex data sets relevant to AD; and harmonizing dementia assessment to enhance cross-national comparisons. 

Understanding Alzheimer's Disease in the Context of the Aging Brain (R01) - PAR-15-357

Organization: NIA 

Posting Date: 09-24-2015 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: The goal of this Funding Opportunity Announcement (FOA) is to establish the role and impact of brain aging in the development and progression of Alzheimers disease (AD).Comprehensive and integrative characterization of brain aging will help to define the mechanisms underlying the shift from healthy brain aging to the neuropathological processes of AD, knowledge that is critical for the design and development of effective interventions.Cross-disciplinary approaches to integrate findings on AD with research on the basic biology and neurobiology of aging are encouraged.  

Capturing Complexity in the Molecular and Cellular Mechanisms Involved in the Etiology of Alzheimer's Disease (R01) - PAR-15-358

Organization: NIA 

Posting Date: 09-25-2015 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: The goal of this Funding Opportunity Announcement (FOA) is to support innovative research focused on understanding the molecular and cellular mechanisms underlying the heterogeneity and multifactorial nature of Alzheimers disease (AD) with the potential to create new or challenge existing scientific paradigms. This FOA encourages individual or collaborative research projects that propose innovative approaches to understand the complex biology of AD aimed to fill critical knowledge gaps.  

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