NIH Guide to Grants and Contracts

The NIH Guide for Grants and Contracts is our official publication for NIH grant policies, guidelines and funding opportunities. We publish daily, and issue a table of contents weekly. Learn more about the NIH Guide and subscribe today!

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Results: 26 to 50 of 1403

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International Research Collaboration on Drug Abuse and Addiction Research (R21) - PA-15-143

Organization: NIDA 

Posting Date: 03-17-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages collaborative research applications on drug abuse and addiction that take advantage of special opportunities that exist outside the United States. Special opportunities include access to unusual talent, resources, populations, or environmental conditions in other countries that will speed scientific discovery. Projects should have relevance to the mission of NIDA and where feasible should address NIDAs international scientific priority areas (http://www.drugabuse.gov/international/research-priorities). While the priorities will change from year to year, in FY15 priority areas include: linkages between HIV/AIDS and drug abuse; prevention, initiation, and treatment of nicotine and tobacco use (especially among vulnerable populations such as children, adolescents, pregnant women, and those with co-morbid disorders); the neuroscience of marijuana and cannabinoids; and the effect of changes in laws and policies on marijuana and its impact. The R21 activity code is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. Projects of limited cost or scope that use widely accepted approaches and methods within well-established fields are better suited for the R03 small grant activity code. 

Alcohol Impairment of Immune Function, Host Defense and Tissue Homeostasis (R01) - PA-15-159

Organization: NIAAA 

Posting Date: 03-26-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications from researchers with broad expertise to study the consequences of alcohol consumption on immune function with a goal toward improving the outcome of patients who abuse alcohol.  

Pilot and Feasibility Clinical Research Grants in Kidney Diseases (R21) - PAR-15-161

Organization: NIDDK 

Posting Date: 03-27-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) is to support Exploratory/Developmental Research Grants (R21) that propose small scale or pilot and feasibility clinical and translational research studies, including epidemiological studies or clinical trials related to kidney disease research. Studies should address important clinical and translational questions and are potentially of high clinical and public health impact. It is anticipated that some projects supported by these grants may lead to full-scale clinical studies including diagnostic strategies, epidemiological studies, or randomized clinical trials of diagnosis, prevention, or treatment of kidney diseases. 

Pilot and Feasibility Clinical Research Grants in Urologic Disorders (R21) - PAR-15-162

Organization: NIDDK 

Posting Date: 03-27-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) is to support Exploratory/Developmental Research Grants (R21) that propose small scale or pilot and feasibility clinical and translational research studies, including epidemiological studies or clinical trials related to urologic disorders research. Studies should address important clinical and translational questions that are potentially of high clinical and public health impact. It is anticipated that some projects supported by these grants may lead to full-scale clinical studies including diagnostic strategies, epidemiological studies, or randomized clinical trials of prevention, diagnosis or treatment of urologic disorders. 

Exploratory/Developmental Clinical Research Grants in Obesity (R21) - PA-15-163

Organization: NIDDK 

Posting Date: 03-27-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages research grant applications from institutions/organizations that propose to conduct exploratory/developmental clinical studies that will accelerate the development of effective interventions for prevention or treatment of overweight or obesity in adults and/or children. Exploratory epidemiological research with a goal of informing translational/clinical research will also be supported within this program.  

Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21) - PA-15-169

Organization: NIDDK 

Posting Date: 04-01-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses of existing data sets relevant to diabetes and selected endocrine and metabolic diseases including thyroid, parathyroid and Cushings diseases and acromegaly; and genetic metabolic disease including cystic fibrosis, lysosomal storage diseases, and disorders of the urea cycle, amino acid metabolism and metal transport where the focus is on peripheral metabolism or organ function; obesity, liver diseases, alimentary GI tract diseases and nutrition; kidney, urologic, and hematologic diseases. The goal of this program is to facilitate research that explores innovative hypotheses through the use of existing data sets. 

Diet and Physical Activity Assessment Methodology (R21) - PAR-15-171

Organization: NIDDK 

Posting Date: 04-02-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages innovative research to enhance the quality of measurements of dietary intake and physical activity. Applications submitted to this FOA may include development of: novel assessment approaches; better methods to evaluate instruments; assessment tools for culturally diverse populations or various age groups, including children and older adults; improved technology or applications of existing technology; statistical methods/modeling to improve assessment and/or to correct for measurement errors or biases; methods to investigate the multidimensionality of diet and physical activity behavior through pattern analysis; or integrated measurement of diet and physical activity along with the environmental context of such behaviors. 

Collaborative Innovation Award, Clinical and Translational Science Award (CTSA) Program (U01) - PAR-15-172

Organization: NCATS 

Posting Date: 04-02-2015 

Expiration Date: 01-25-2018 

Activity Code: U01 

Summary: The purpose of this funding opportunity announcement (FOA) is to invite applications to stimulate innovative collaborative research in the NCATS Clinical and Translational Science Award (CTSA) consortium. 

Alzheimer's Drug-Development Program (U01) - PAR-15-174

Organization: NIA 

Posting Date: 04-02-2015 

Expiration Date: 01-25-2018 

Activity Code: U01 

Summary: The goal of this Funding Opportunity Announcement (FOA) is to provide funding support for the pre-clinical and early stage clinical (Phase I) development ofsmall-molecule and biologic therapeutic agents that prevent Alzheimer's disease (AD), slow its progression or treat its cognitive and behavioral symptoms.Participants in this program will receive funding for therapy development activities such as medicinal chemistry, pharmacokinetics (PK), Absorption, Distribution, Metabolism, Excretion, Toxicology (ADMET), efficacy in animal models, formulation development, chemical synthesis under Good Manufacturing Practices (GMP), Investigational New Drug (IND) enabling studies and initial Phase I clinical testing. This program does not support research on basic mechanisms of disease, development of biomarkers, devices, non-pharmacological interventions (e.g., exercise, diet, cognitive training), repurposed drugs and combinations therapies or, discovery activities such as high throughput screening and hit optimization. 

Phenotypic and Functional Studies on FOXO3 Human Longevity Variants to Inform Potential Therapeutic Target Identification Research (R01) - PAR-15-175

Organization: NIA 

Posting Date: 04-03-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: The focus of this Funding Opportunity Announcement (FOA) is on in vivo human studies, and in vitro studies on human cells or tissues, aimed at potential identification of therapeutic targets or and/or testing of interventions for healthy aging. Potential therapeutic targets include FOXO3 itself and upstream and downstream regulators in pathways mediated by FOXO3. The range of research areas of interest in this FOA includes studies that: 1) examine in vivo phenotypic effects of human FOXO3 variants, and/or 2) elucidate effects of these variants on cellular functions and the pathways that mediate them, and/or 3) identify and evaluate candidate therapeutic targets (e.g., target validation studies, testing of candidate compounds) for potential interventions based on FOXO3 functional pathways.  

Pilot and Feasibility Studies in Preparation for Drug and Alcohol Abuse Prevention Trials (R34) - PA-15-177

Organization: NIDA 

Posting Date: 04-07-2015 

Expiration Date: 01-25-2018 

Activity Code: R34 

Summary: This Funding Opportunity Announcement (FOA) for R34 applications seeks to support: (a) pilot and/or feasibility testing of innovative new, revised, or adapted prevention intervention approaches to prevent or delay the initiation and onset of drug and alcohol use, the progression to problem use or alcohol and other substance use disorder, reduce drinking and driving and deaths related to impaired driving andthe drug- or alcohol-related acquisition or transmission of HIV infection and viral hepatitis among diverse populations and settings; and (b) pre-trial feasibility testing for prevention services and systems research. It is expected that research conducted via this R34 mechanism will consist of early stage efficacy, effectiveness or services research that will provide intervention pilot and/or feasibility data that is a pre-requisite for preparing and submitting subsequent applications for larger scale drug or alcohol abuse prevention and/or drug- or alcohol-related HIV prevention intervention studies. This R34 FOA does not support applications for which the sole focus is development of intervention protocols, manuals, or the standardization of protocols; rather, any development work must be imbedded within a pilot/feasibility study.Of particular interest are prevention interventions targeting the healthcare system.  

T1 Translational Research: Novel Interventions for Prevention and Treatment of Age-related Conditions (R21) - PAR-15-190

Organization: NIA 

Posting Date: 04-28-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This funding opportunity announcement (FOA) encourages exploratory/developmental research projects to accelerate the pace of development of novel therapeutics involving biologics, pharmacological and non-pharmacological approaches for preventing and treating key health issues affecting the elderly. For the purposes of this FOA, T1 translational research on aging is defined as the application of basic and clinical biomedical findings towards the development of new strategies for prevention and treatment of age-related pathologies.  

T2 Translational Research: Research Leading to New Health Care Practices, Community Programs and Policies Affecting Older Persons (R21) - PAR-15-191

Organization: NIA 

Posting Date: 04-28-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This funding opportunity announcement (FOA) encourages exploratory/developmental research projects on translational research (T2) directed towards development of health care practices, community programs and policies, including monitoring and quality improvement for pharmacological and non-pharmacological approaches for preventing and treating key health issues affecting the elderly. For the purposes of this FOA, T2 translational research on aging is defined as research to gather information needed to develop or evaluate methods of translating results from clinical studies into everyday clinical practice and health decision making (e.g., adapting an efficacious intervention for application in clinical practice and evaluating its effectiveness in different clinical settings). Methods for T2 translational research include but are not limited to intervention studies, systematic reviews, meta-analysis, outcomes research and implementation research. 

Studies at Periviable Gestation (R21) - PA-15-198

Organization: NICHD 

Posting Date: 05-04-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: The goals of this Funding Opportunity Announcement (FOA) are to focus on projects that will provide an evidence base to guide therapies and treatment at periviable gestational age for both mothers and their infants.  

Studies at Periviable Gestation (R01) - PA-15-200

Organization: NICHD 

Posting Date: 05-04-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) focuses on projects that will provide an evidence base to guide therapies and treatment at periviable gestational age for both mothers and their infants.  

Studies at Periviable Gestation (R03) - PA-15-199

Organization: NICHD 

Posting Date: 05-04-2015 

Expiration Date: 01-25-2018 

Activity Code: R03 

Summary: This Funding Opportunity Announcement (FOA) focuses on projects that will provide an evidence base to guide therapies and treatment at periviable gestational age for both mothers and their infants.  

Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Abuse (R34) - PA-15-250

Organization: NIDA 

Posting Date: 05-08-2015 

Expiration Date: 01-25-2018 

Activity Code: R34 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to encourage pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies, designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related services, as well as services for comorbid medical and mental disorder conditions. Relevant approaches may include both those that are novel, and those that are commonly used in practice but lack an evidence base. This FOA provides resources for assessing the feasibility, acceptability, and utility of these approaches.  

Health Services and Economic Research on the Prevention and Treatment of Drug, Alcohol, and Tobacco Abuse (R03) - PA-15-252

Organization: NIDA 

Posting Date: 05-08-2015 

Expiration Date: 01-25-2018 

Activity Code: R03 

Summary: This Funding Opportunity Announcement (FOA) encourages small grant applications (R03) to conduct rigorous health services and economic research to maximize the delivery of efficient, high-quality drug, tobacco, and alcohol prevention, treatment, and recovery support services. Examples of such research include: (1) clinical quality improvement; (2) quality improvement in services organization and management; (3) implementation research; (4) economic and cost studies; and (5) development or improvement of research methodology, analytic approaches, and measurement instrumentation used in the study of drug, alcohol, and tobacco prevention, treatment, and recovery services.  

Health Services and Economic Research on the Prevention and Treatment of Drug, Alcohol, and Tobacco Abuse (R21) - PA-15-253

Organization: NIDA 

Posting Date: 05-08-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages R21 grant applications to conduct rigorous health services and economic research to maximize the delivery of efficient, high-quality drug, tobacco, and alcohol prevention, treatment, and recovery support services. Examples of such research include: (1) clinical quality improvement; (2) quality improvement in services organization and management; (3) implementation research; (4) economic and cost studies; and (5) development or improvement of research methodology, analytic approaches, and measurement instrumentation used in the study of drug, alcohol, and tobacco prevention, treatment, and recovery services.  

Human Studies to Evaluate Promising Medications to Treat Alcohol Use Disorder (R21) - PA-15-254

Organization: NIAAA 

Posting Date: 05-13-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: The objective of this Funding Opportunity Announcement (FOA) is to encourage applications that use human laboratory paradigms and/or clinical trials to evaluate the safety and efficacy of novel or re-purposed compounds, that bind to new targets, for treatment of alcohol use disorder (AUD) or AUD with a comorbid post-traumatic stress disorder. 

Human Studies to Evaluate Promising Medications to Treat Alcohol Use Disorder (R01) - PA-15-256

Organization: NIAAA 

Posting Date: 05-13-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: The objective of this Funding Opportunity Announcement (FOA) is to encourage applications that use human laboratory paradigms and/or clinical trials to evaluate the safety and efficacy of novel or re-purposed compounds, that bind to new targets, for treatment of alcohol use disorder (AUD) or AUD with a comorbid post-traumatic stress disorder. 

Human Studies to Evaluate Promising Medications to Treat Alcohol Use Disorder (R03) - PA-15-255

Organization: NIAAA 

Posting Date: 05-13-2015 

Expiration Date: 01-25-2018 

Activity Code: R03 

Summary: The objective of this Funding Opportunity Announcement (FOA) is to encourage applications that use human laboratory paradigms and/or clinical trials to evaluate the safety and efficacy of novel or re-purposed compounds, that bind to new targets, for treatment of alcohol use disorder (AUD) or AUD with a comorbid post-traumatic stress disorder. 

The Health of Sexual and Gender Minority (SGM) Populations (R01) - PA-15-261

Organization: NICHD 

Posting Date: 05-18-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: The National Institutes of Health (NIH) is committed to supporting research that will increase scientific understanding of the health status of diverse population groups and thereby improve the effectiveness of health interventions and services for individuals within those groups. Priority is placed on understudied populations with distinctive health risk profiles. This funding opportunity announcement (FOA) focuses on sexual and gender minority (SGM) populations, including lesbian, gay, bisexual, transgender, and intersex populations. Basic, social, behavioral, clinical, and services research relevant to the missions of the sponsoring Institutes and Centers may be proposed. 

The Health of Sexual and Gender Minority (SGM) Populations (R03) - PA-15-262

Organization: NICHD 

Posting Date: 05-18-2015 

Expiration Date: 01-25-2018 

Activity Code: R03 

Summary: The National Institutes of Health (NIH) is committed to supporting research that will increase scientific understanding of the health status of diverse population groups and thereby improve the effectiveness of health interventions and services for individuals within those groups. Priority is placed on understudied populations distinctive health risk profiles. This funding opportunity announcement (FOA) focuses on sexual and gender minority (SGM) populations, including lesbian, gay, bisexual, transgender, and intersex populations. Basic, social, behavioral, clinical, and services research relevant to the missions of the sponsoring Institutes and Centers may be proposed.  

The Health of Sexual and Gender Minority (SGM) Populations (R21) - PA-15-263

Organization: NICHD 

Posting Date: 05-18-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: The National Institutes of Health (NIH) is committed to supporting research that will increase scientific understanding of the health status of diverse population groups and thereby improve the effectiveness of health interventions and services for individuals within those groups. Priority is placed on understudied populations with distinctive health risk profiles. This funding opportunity announcement (FOA) focuses on sexual and gender minority (SGM) populations, including lesbian, gay, bisexual, transgender, and intersex populations. Basic, social, behavioral, clinical, and services research relevant to the missions of the sponsoring Institutes and Centers may be proposed.  

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