NIH Guide to Grants and Contracts

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ALZHEIMER"S DISEASE CENTER COMMUNITY OUTREACH EDUCATION PROGRAMS - RFA-AG-92-001

Organization: NIA 

Posting Date: 01-10-1992 

Expiration Date: 03-25-1992 

Activity Code: R25 

Summary: The purpose of this Request for Applications (RFA) is to invite grant applications for the support of community outreach education programs from recipients of National Institute on Aging (NIA) Alzheimer"s Disease Research Centers (P50) and Alzheimer"s Disease Center Core Grants (P30) and institutions that have equivalent programs. It is anticipated that these education programs will result in increased community efforts related to Alzheimer"s disease (AD), earlier detection of dementing disorders, better education and assistance programs for the families, and the systematic application of the best available methods for treatment and care of Alzheimer"s disease patients. The primary purpose is to encourage Alzheimer"s Disease Centers to expand their role in technology transfer by providing state-of-the-art information about detection, diagnosis, treatment, management and family care of Alzheimer"s disease to community professionals and relevant community organizations. Underserved, women, and minority populations should receive high priority in carrying out these objectives.  

EVALUATION OF THE USE OF GUIDELINES IN LARGE GROUP PRACTICES - RFA-HS-92-002

Organization: AHRQ 

Posting Date: 01-24-1992 

Expiration Date: 03-25-1992 

Activity Code: U10 

Summary: The Agency for Health Care Policy and Research (AHCPR) invites applications for cooperative agreements to demonstrate research methods for evaluation of alternative strategies for implementation of clinical practice guidelines and the effects of implementing practice guidelines on the delivery of primary care in large-group practices. The specific clinical practice guidelines to be evaluated are: (1) those developed by the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC), and (2) the forthcoming guidelines for the detection and management of depressed patients in primary care settings, developed with the support of the AHCPR Forum on Quality and Effectiveness in Health Care. Studies must include an experimental or quasi-experimental design for evaluating at least two approaches for implementing the guidelines in group practice settings. One method must incorporate the principles of continuous quality improvement (CQI), additional strategies based on relevant theories of practitioner and organizational behavior may be selected by the Principal Investigators.  

BIOMEDICAL RESEARCH SUPPORT SHARED INSTRUMENTATION GRANT - PA-92-037

Organization: NCRR 

Posting Date: 01-24-1992 

Expiration Date: 03-27-1992 

Activity Code: S10 

Summary: The National Center for Research Resources (NCRR) is continuing its competitive Biomedical Research Support (BRS) Shared Instrumentation Grant (SIG) Program initiated in Fiscal Year 1982. The program was established in recognition of the long-standing need in the biomedical research community to cope with rapid technological advances in instrumentation and the rapid rate of obsolescence of existing equipment. The objective of the program is to make available to institutions with a high concentration of Public Health Service (PHS)-supported biomedical investigators research instruments that can only be justified on a shared-use basis and for which meritorious research projects are described. 

NIAID INSTITUTIONAL TRAINING AWARDS FOR CLINICAL RESEARCH ON THE ACQUIRED IMMUNODEFICIENCY SYNDROME - RFA-AI-92-004

Organization: NIAID 

Posting Date: 01-24-1992 

Expiration Date: 04-09-1992 

Activity Code: T32 

Summary: The purpose of this RFA is to solicit applications from institutions able to develop a clinical research training program that provides training opportunities to outstanding new investigators who have shown an interest in, and commitment to, clinical research on HIV disease and the AIDS. Trainees will learn the tools of research to solve clinical problems in HIV infection. This program will target a variety of disciplines that work with patient clinical material or other clinical data in clinical research.  

MULTICENTER STUDIES OF DIET AND LIPOPROTEINS IN HUMANS - RFA-HL-92-003

Organization: NHLBI 

Posting Date: 02-28-1992 

Expiration Date: 04-24-1992 

Activity Code:  

Summary: The RFA, "Multicenter Studies of Diet and Lipoproteins in Humans," was published in the NIH Guide for Grants and Contracts, Vol. 20, No. 47, December 20, 1991. Investigators submitting applications for both a clinical center and a field center must submit separate applications for each. Each application must be self-contained, and must indicate the Principal and Co-Investigators, must include its own budget and all appropriate assurances, and indicate clearly whether the application is for a Field Center or a Coordinating Center.  

COOPERATIVE CONTRACEPTIVE DEVELOPMENT RESEARCH CENTERS PROGRAM - RFA-HD-92-006

Organization: NICHD 

Posting Date: 01-10-1992 

Expiration Date: 04-25-1992 

Activity Code: U54 

Summary: The National Institute of Child Health and Human Development (NICHD) invites applications from investigators willing to participate with the NICHD, under a cooperative agreement, in establishing a Centers program designed to conduct comprehensive research on the development of new contraceptive products. It is anticipated that ultimately three Centers will participate in this program and that the award period will be five years. Two Centers were funded under a prior Request for Applications (RFA) and one Center will be funded as the result of the present RFA. The aim of these Centers will be to conduct a wide range of research activities that, with time, may result in the development of clinically useful modalities. The Center should have, or should be able to develop, a broad range of research activities that are classified as a research and development (R&D) program. It is understood that certain activities may have to be conducted outside a specific Center via arrangements with other Centers or other institutions. By utilizing the framework of an interdisciplinary approach, the Centers can conduct R&D activities that are beyond the capabilities of individual investigators.  

MENTAL HEALTH INSTITUTIONAL CLINICAL TRAINING GRANTS: PROFESSIONAL TRAINING FOR RACIAL/ETHNIC MINORITY AND DISADVANTAGED STUDENTS - RFA-MH-92-008

Organization: NIMH 

Posting Date: 02-21-1992 

Expiration Date: 04-25-1992 

Activity Code: T01 

Summary: This program is designed to support recruitment and education of racial/ethnic minority and disadvantaged students to become professionals in the core mental health disciplines of social work, psychiatric nursing, psychology, psychiatry, and marriage and family therapy. The term "minority" in this announcement refers to Blacks, Hispanics, Asian/Pacific Islanders (including Native Hawaiians and Samoans), and American Indians/Alaska Natives. The definition of disadvantaged students is left to the applicant institution that must justify it. It could include the hearing impaired or those with other handicapping conditions but would not extend to individuals whose sole disadvantage is economic.  

EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION PROJECTS - RFA-OD-92-002

Organization: NIH 

Posting Date: 01-31-1992 

Expiration Date: 04-28-1992 

Activity Code: C06 

Summary: The main objective of this construction program is to facilitate the conduct of biomedical research by providing funds for construction of new facilities and for the purchase of fixed research equipment essential for the operation of these facilities. Support may be requested for the construction of new facilities and additions or renovations to existing facilities to meet the biomedical research and/or biomedical research support needs of an institution, or of a research group at that institution or elsewhere that utilizes the resources of that institution. The purpose of the proposed facility must be within the scope of one of the statutes authorizing the awards. Those statutes authorize construction grants for the National Cancer Program (Section 413(b)(6)(B), PHS Act), construction grants for the National Heart, Blood Vessel, Lung and Blood Diseases and Blood Resources Program (Section 421(b)(2)(B), PHS Act), construction grants for the vision research program of the National Eye Institute (Section 455, PHS Act), and construction grants for the NIH AIDS research programs (Section 2351(a)(7)(B), PHS Act).  

DOMESTIC ANIMAL MODELS FOR RETROVIRUS-ASSOCIATED HUMAN CANCERS - RFA-CA-92-007

Organization: NCI 

Posting Date: 01-17-1992 

Expiration Date: 04-29-1992 

Activity Code: R01 

Summary: Retroviruses isolated from mammalian species have the potential to provide valuable basic information on the etiology and mechanism(s) of cancer induction by viruses and to serve as models for evaluating antiviral agents prior to human clinical trials. The occurrence of neoplastic sequelae in retrovirus-infected animals supports the view that these viruses may be directly or indirectly involved in the etiology of malignancies. The identification and development of suitable animal models of viral neoplasia may aid in investigations of the mechanisms of cancer initiation and progression, ultimately providing a better understanding of the role of viruses in the etiology of human cancer. The Congress, in both FY 90 and FY 92, has expressed its interest in retroviral infections in large domestic animals as excellent models for retroviral-induced diseases in humans such as leukemia, lymphosarcoma, and AIDS.  

CANCER PREVENTION AND CONTROL RESEARCH SMALL GRANT PROGRAM - RFA-CA-92-004

Organization: NCI 

Posting Date: 01-24-1992 

Expiration Date: 05-07-1992 

Activity Code: R03 

Summary: The Division of Cancer Prevention and Control (DCPC) of the National Cancer Institute (NCI) invites Small Research Grant (R03) applications from interested investigators. This program is designed to aid and facilitate the growth of a nationwide cohort of scientists with a high level of research expertise in the field of human cancer control intervention research.  

DEVELOPMENT GRANTS: MINORITY ORAL HEALTH RESEARCH CENTERS - RFA-DE-92-001

Organization: NIDCR 

Posting Date: 02-14-1992 

Expiration Date: 05-07-1992 

Activity Code: P20 

Summary: The National Institute of Dental Research (NIDR) and the Research Centers in Minority Institutions (RCMI) Program of the National Center for Research Resources (NCRR) invite applications for grants for the development of Regional Research Centers for Minority Oral Health (RRCMOH). The purpose of these Phase I grants is to enable minority dental schools or dental schools serving large minority populations to develop the necessary alliances and organizational structure necessary to compete for Phase II grants for the support of RRCMOHs. A Request for Applications (RFA) for Phase II, five-year grants for support of RRCMOHs will be available in 1994. The objectives of the RRCMOH initiative are to: (1) conduct research to improve the oral health of U.S. racial and ethnic minorities; (2) enhance the research capabilities and participation of members of racial and ethnic minorities in oral health research; and (3) develop and strengthen the minority oral health research infrastructure of minority dental schools and of majority dental schools serving large minority populations. African Americans (Blacks), Hispanics, Asians and Pacific Islanders, and American Indians and Alaskan Natives are considered to be racial or ethnic minorities.  

THROMBOCYTOPENIAS IN WOMEN AND NEONATES - RFA-HL-92-006

Organization: NHLBI 

Posting Date: 02-14-1992 

Expiration Date: 05-08-1992 

Activity Code: R01 

Summary: The Division of Blood Diseases and Resources (DBDR), National Heart, Lung, and Blood Institute (NHLBI) invites applications for studies to better define the properties and clinical relevance of the antiplatelet antibodies in alloimmune and autoimmune thrombocytopenias in women and neonates. The knowledge gained is expected to lead to improved therapy for this patient population.  

EXPLORATORY CENTERS FOR BIOBEHAVIOR SYMPTOM MANAGEMENT - RFA-NR-92-002

Organization: NINR 

Posting Date: 02-07-1992 

Expiration Date: 05-08-1992 

Activity Code:  

Summary: The notice of availability for this Request for Applications was published in the NIH Guide for Grants and Contracts on January 24, 1992, Vol. 21, No. 3, Part II of II. The section, RESEARCH OBJECTIVES, contained an error in the third paragraph. This entire paragraph, shown below, indicates that "symptoms specific to psychiatric disorders are not included in the scope of this RFA."  

EXPLORATORY CENTERS FOR BIOBEHAVIORAL SYMPTOM MANAGEMENT - RFA-NR-92-02

Organization: NINR 

Posting Date: 01-24-1992 

Expiration Date: 05-08-1992 

Activity Code: P20 

Summary: The National Center for Nursing Research (NCNR) invites the submission of exploratory center (P20) applications for the development of innovative clinical assessment and management strategies for symptoms commonly experienced by acutely and chronically ill patients. These clinical assessment and management strategies must address the biological and behavioral interface of the selected symptom(s). The center must have an interdisciplinary approach with a focus on clinical research, basic research, or a combination.  

INITIATIVES FOR MINORITY STUDENTS: BRIDGES TO THE FUTURE - RFA-GM-92-002

Organization: NIGMS 

Posting Date: 03-06-1992 

Expiration Date: 05-13-1992 

Activity Code: R25 

Summary: The National Institute of General Medical Sciences (NIGMS) and the Office of Minority Programs (OMP), National Institutes of Health (NIH), solicit applications for two new initiatives aimed at increasing the number of underrepresented minorities entering careers in biomedical research. The programs target two different underrepresented minority student populations, those in terminal Master of Science (M.S.) degree programs and those in two-year junior or community colleges, since these have been identified as two key transition points for students considering research careers. These initiatives seek to broaden and expand existing programs and to encourage the development of new and innovative approaches to improve the academic competitiveness of underrepresented minority students graduating from these programs, thereby facilitating their transition into the next stage towards careers in biomedical research.  

PREPARATION FOR AIDS/HIV VACCINE EVALUATIONS - RFA-AI-92-005

Organization: NIAID 

Posting Date: 02-28-1992 

Expiration Date: 05-14-1992 

Activity Code: R21 

Summary: The purpose of this Request for Applications (RFA) is to support developmental projects designed to establish collaborative studies, involving U.S. and foreign institutions, that (1) develop baseline data for determining the feasibility of conducting AIDS/HIV vaccine trials in international settings and (2) develop capabilities at international sites to conduct HIV vaccine efficacy trials. The NIAID anticipates initiating clinical trials of AIDS/HIV vaccines by December 1993 at domestic sites and shortly thereafter at international locations.  

IMPLEMENTATION GRANTS FOR GENE THERAPY PROGRAMS IN CANCER TREATMENT - RFA-CA-92-013

Organization: NCI 

Posting Date: 01-24-1992 

Expiration Date: 05-16-1992 

Activity Code: P01 

Summary: The Division of Cancer Treatment (DCT) of the National Cancer Institute (NCI) invites program project grant applications (P01) from interested investigators to establish interactive Gene Therapy Programs (GTP) with the goal of conducting gene therapy clinical trials for cancer treatment. The purpose of this RFA is to promote the design and implementation of clinical trials of gene therapy, to support the requisite preclinical studies establishing the scientific and technical basis for human studies, and to foster the development of interactions between basic scientists and clinical researchers necessary for bringing gene therapy to patient trials. The program project grant mechanism will support the establishment of broadly based, multi-disciplinary and multi-institutional research programs centered around this goal.  

INTERMEDIATE ENDPOINTS AND THEIR MODULATION BY CHEMOPREVENTIVE AGENTS - RFA-CA-92-006

Organization: NCI 

Posting Date: 02-21-1992 

Expiration Date: 05-20-1992 

Activity Code: U01 

Summary: The Division of Cancer Prevention and Control (DCPC), National Cancer Institute (NCI), invites applications for cooperative agreements to support clinical trials that are directed toward examining the role of various chemopreventive agents and/or diet in the prevention of cancer.  

COOPERATIVE AGREEMENT FOR A MULTI-SITE TREATMENT STUDY OF ATTENTION- DEFICIT HYPERACTIVITY DISORDER/ATTENTION DEFICIT DISORDER - RFA-MH-92-003

Organization: NIMH 

Posting Date: 03-06-1992 

Expiration Date: 05-20-1992 

Activity Code: U01 

Summary: The National Institute of Mental Health (NIMH) announces a Request for Applications (RFA) for "Multimodal Treatment Study of Attention-Deficit Hyperactivity Disorder and Attention Deficit Disorder (ADHD/ADD)." This program is a five-year multi-site collaborative study intended to address a range of issues concerning ADHD as emphasized by the Institute of Medicine study "Research on Children and Adolescents with Mental, Behavioral, and Developmental Disorders," the NIMH "National Plan for Research on Child and Adolescent Mental Disorders," the "Healthy People 2000" objectives in the area of mental disorders in children and adolescents (6.3), and the existing literature. Foremost among these are treatment issues subsumed by the question: Under what circumstances and patient characteristics (e.g., comorbid conditions, family socioeconomic background, metabolic/nutritional status, physical/neurological findings, neurophysiological/neuropsychological status, gender, age) do which treatment combinations (specific medication, behavior therapy, parent training, school-based intervention), have what impacts (improvement, stasis, deterioration) on what domains of child functioning (cognitive, academic, behavioral, neurophysiological, neuropsychological, peer relations, family relations), for how long (short vs. long term), to what extent (effect sizes, normal vs. pathological range), and why (processes underlying change)? These questions form the scaffolding for a multi-site, multimodal treatment study of ADHD/ADD and its comorbid conditions. During the first year, the Principal Investigators (PIs) of the collaborating sites will develop a common protocol from their pooled applications. This common protocol will be designed to (1) maximize the potential of the cross-site data set to address the treatment questions outlined above and (2) support major studies focusing on related issues of the assessment, comorbidity, etiology, and natural history of ADHD with its comorbid conditions. In year five, data will be analyzed, scientific reports will be prepared for publication as warranted by initial study findings, and the scientific merit of examining long-term outcomes will be evaluated.  

SHORT-TERM CLINICAL TRAINING GRANTS IN DIAGNOSIS AND TREATMENT OF DEPRESSIVE DISORDERS - RFA-MH-92-009

Organization: NIMH 

Posting Date: 02-21-1992 

Expiration Date: 05-20-1992 

Activity Code: T15 

Summary: As part of the Depression Awareness, Recognition and Treatment (D/ART) program, the National Institute of Mental Health (NIMH) seeks applications for programs of short-term (not to exceed five days duration) continuing education. Each program will be carried out at several locations (minimum of six different sites per year) and will provide continuing education for primary care providers and mental health professionals. Support is available for the development, implementation, and evaluation of training programs that are designed to foster more effective recognition, diagnosis, and treatment of major depressive disorders including manic depression and clinical depression. This initiative is intended to provide for the development of effective training that is directly tied to major recent research findings and clinical knowledge and that incorporates didactic and experiential modes of teaching; it is not, however, designed to test training models. The focus is on training providers to more effectively diagnose and treat clinical depression in adults and adolescents; childhood depression does not fall within the scope of this announcement.  

SHORT-TERM GRANTS FOR TRAINING MEDICAL STUDENTS IN THE DIAGNOSIS AND TREATMENT OF DEPRESSIVE DISORDERS - RFA-MH-92-010

Organization: NIMH 

Posting Date: 02-21-1992 

Expiration Date: 05-20-1992 

Activity Code: T15 

Summary: As part of the Depression Awareness, Recognition, and Treatment (D/ART) program, the National Institute of Mental Health (NIMH) seeks applications from medical schools to develop and implement training of pre-doctoral medical students in the diagnosis and treatment of clinical depression according to a basic curriculum presented in this Request for Application (RFA). Support is available for the detailed development of this curriculum, its implementation, and evaluation of its educational effectiveness and impact. The goal of the training is to prepare medical students to deal with depressive disorders (including major depression and bipolar disorder) as these disorders appear in medical settings. It is not designed to provide specialty training for psychiatric residents.  

QUANTITATION OF TUMOR RESPONSE TO TREATMENT: A THREE-DIMENSIONAL APPROACH - RFA-CA-92-008

Organization: NCI 

Posting Date: 01-24-1992 

Expiration Date: 05-22-1992 

Activity Code: R01 

Summary: The Radiation Research Program (RRP), Division of Cancer Treatment (DCT), of the National Cancer Institute (NCI), invites research grant applications that advance current methods of imaging-based tumor volumetric analysis for optimization of response assessment in oncology. The objective of this Request for Applications (RFA) is to support meritorious research in the development of a three-dimensional (3D) approach to serial quantitation of tumor volume. The proposed research is expected to improve clinical management in oncology and to facilitate the development and evaluation of anti-neoplastic drugs and other treatment modalities in cancer patients.  

NATIONAL HISPANIC LEADERSHIP INITIATIVE ON CANCER - RFA-CA-92-009

Organization: NCI 

Posting Date: 03-13-1992 

Expiration Date: 05-22-1992 

Activity Code: U01 

Summary: The Division of Cancer Prevention and Control (DCPC), National Cancer Institute (NCI), invites cooperative agreement applications from organizational entities to participate, with the assistance of the NCI, in establishing a culturally and linguistically credible and efficacious national community outreach cancer prevention and control program for Hispanic Americans residing in the United States. The program will advance through stages of planning, development, implementation, and evaluation and consist of cancer awareness activities aimed at reducing cancer incidence and mortality and increasing survival rates in targeted Hispanic subgroups. The benefits that will accrue from implementation of the objectives of this RFA will all be applicable to other populations that may reside within the specified geographical areas of the Hispanic American community.  

NATIONAL BLACK LEADERSHIP INITIATIVE ON CANCER - RFA-CA-92-010

Organization: NCI 

Posting Date: 03-13-1992 

Expiration Date: 05-22-1992 

Activity Code: U01 

Summary: The National Cancer Institute (NCI) through the Division of Cancer Prevention and Control (DCPC), Cancer Control Science Program (CCSP), National Outreach Initiatives Branch (NOIB), invites cooperative agreement applications from organizations to participate, with the assistance of the NCI, in establishing a cancer prevention and control community outreach program.  

APPALACHIA LEADERSHIP INITIATIVE ON CANCER - RFA-CA-92-011

Organization: NCI 

Posting Date: 03-13-1992 

Expiration Date: 05-22-1992 

Activity Code: U01 

Summary: The National Outreach Initiatives Branch (NOIB), Division of Cancer Prevention and Control (DCPC), National Cancer Institute (NCI), invites cooperative agreement applications from organizations to participate in establishing a strong, cancer control outreach program in Appalachia (as defined in the research objectives section below). The long-term goals of the program are to achieve reductions in cancer incidence and mortality, increases in cancer survival, and increases in the diagnosis of cancers at earlier stages within the Appalachian region. This Request for Applications (RFA) invites applications that propose mobilization of community lay and professional leaders to develop and support community cancer control coalitions throughout Appalachia. These coalitions will design and implement long-range, comprehensive, multi-disciplinary, and community-wide cancer control outreach projects and stimulate greater cancer control data collection and research efforts. As a result, measurable improvements are expected in knowledge about prevention and early detection of cancer and access and utilization of diagnostic and treatment services for cancer.  

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