Animal numbers

• FAQ. Is the IACUC responsible for tracking animal usage?
• Lab Animal. 2010; 39(2). (PDF - 149 KB) Breeding without research.
• Lab Animal. 2006; 35(1). Should you count your mice before they're weaned?
• Contemporary Topics. 1997; 36(2):47-50, question #7.

Animal reuse

• Lab Animal. 2008; 37(2). (PDF - 95 KB) Collaborative studies and animal reuse.
  
• Lab Animal. 2007; 36(3). (PDF - 71 KB) One animal, two protocols – an appropriate application of the 3Rs?

Animal transfer

• FAQ. May an investigator transfer animals and research to an institution different than the grantee institution?
  
• Lab Animal. 2001; 30(3). A Pain in the Rat.

Emergency, weekend and holiday care

• Lab Animal. 2011; 40(11). (PDF - 179 KB) Quick action for an injured mouse.

Environmental enrichment

• FAQ. Is social housing required for nonhuman primates when housed in a research setting?
• FAQ. Should positive reinforcement training be used for nonhuman primates?
• FAQ. May performance standards determine environmental enrichment issues?
• NOT-OD-10-121. Report on Site Visits to Chimpanzee Facilities and Associated Resources to Aid Grantee Institutions
• View "AC and OLAW Perspective on Nonhuman Primate Enrichment and Social Housing" (Flash)
• Report on OLAW Site Visits to Chimpanzee Facilities (PDF - 54 KB)

Ethics

• OPRR Reports. 97-02, 5/30/1997. NASA Principles for the Ethical Care and Use of Animals
• View "Ethics and IACUC Responsibility" (Flash - 55 mins)

Euthanasia methods

• FAQ. Is the use of carbon dioxide an acceptable euthanasia agent?
• NOT-OD-08-005. Implementation of the Revised American Veterinary Medical Association Guidelines on Euthanasia
• NOT-OD-02-062. PHS Policy on Humane Care and Use of Laboratory Animals Clarification Regarding Use of Carbon Dioxide for Euthanasia of Small Laboratory Animals

Expired materials

• FAQ. May investigators use expired pharmaceuticals, biologics, and supplies in animals?

Food/fluid regulation

• FAQ. May investigators restrict animals' food and fluid?

Housing practices

• FAQ. May the IACUC approve deviations from the Guide for rodent (mice and rats) cage density?
• FAQ. May performance standards determine housing issues?
• FAQ. Can performance standards be used in determining rabbit housing practices?
• Lab Animal. 2007; 36(10). (PDF - 165 KB) Considerations for determining optimal mouse caging density.

Lab animal as pet

• FAQ. Can IACUCs authorize the adoption of research animals as pets after the animals are no longer needed for study?
• P.I. eAlert.2009; No. 6. (PDF - 299 KB) Lab Rat O.K. as Pet?

Mouse ascites

• FAQ. Is the mouse ascites method an acceptable method of monoclonal antibody production?
• NOT-OD-00-019. Office of Extramural Research Guidance Concerning the Production of Monoclonal Antibodies in Animals
• OPRR Reports. 98-01, 11/17/1997. Production of Monoclonal Antibodies Using Mouse Ascites Method

Multiple survival surgeries

• FAQ. Are major multiple survival surgical procedures permitted on a single animal?
• FAQ. Are laparoscopic procedures considered major surgery?
• Lab Animal eAlert. 2010; No. 17. (PDF - 336 KB) Is a laparoscopic serial liver biopsy considered ‘major' animal surgery?
• Contemporary Topics. 1997; 36(2):47-50, question #5.

Non-pharmaceutical grade compounds

• FAQ. May investigators use non-pharmaceutical grade compounds in animals?
• View "Use of Non-Pharmaceutical-Grade Chemicals and Other Substances in Research with Animals" (Windows Media Player - 42 Mins)
• Lab Animal. 2003; 32(9):33-36, question #3.

Shipping

• FAQ. What are the institution's responsibilities in ensuring that animals are shipped safely and in reporting adverse events that occur in shipment of animals to or from the institution?

Surgery

• FAQ. What are the requirements for conducting rodent survival surgery?
• Lab Animal. 2010; 39(8). (PDF - 170 KB) Noncompliance in survival surgery technique.
• ILAR News. 1993; 35(3-4):47-49, question #1.

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