SUMMER RESEARCH TRAINING IN AGING FOR MEDICAL STUDENTS RELEASE DATE: August 6, 2004 RFA NUMBER: RFA-AG-05-002 Update: The following update relating to this announcement has been issued: September 25, 2009 - This RFA has been reissued as (RFA-AG-10-007). EXPIRATION DATE: November 19, 2004 Department of Health and Human Services (DHHS) PARTICIPATING ORGANIZATIONS: National Institutes of Health (NIH) (http://www.nih.gov/) The John A. Hartford Foundation (http://www.jhartfound.org/) The American Federation for Aging Research (http://www.afar.org/) COMPONENT OF PARTICIPATING ORGANIZATION: National Institute on Aging (NIA) (http://www.nia.nih.gov/) CATALOG OF FEDERAL DOMESTIC ASSISTANCE NUMBER: 93.866 LETTER OF INTENT RECEIPT DATE: October 18, 2004 APPLICATION RECEIPT DATE: November 18, 2004 THIS RFA CONTAINS THE FOLLOWING INFORMATION: o Purpose of this RFA o Research Objectives o Mechanism of Support o Funds Available o Eligible Institutions o Eligible Training Program Directors o Trainee Eligibility Requirements o Special Requirements o Where to Send Inquiries o Letter of Intent o Submitting an Application o Supplementary Instructions o Peer Review Process o Review Criteria o Receipt and Review Schedule o Award Criteria o Required Federal Citations PURPOSE OF THIS RFA The National Institute on Aging, in collaboration with the American Federation for Aging Research (AFAR), the John A. Hartford Foundation and other foundation partners, invites applications for a new coordinated national program to provide short-term research training for medical students. This program continues and strengthens the AFAR/Hartford Foundation Medical Student Geriatric Scholars Program, established in 1994, which provided short-term research, clinical and didactic support for medical students, in allopathic or osteopathic schools, to expose them to career opportunities in aging-related research and academic geriatrics. RESEARCH OBJECTIVES NIA, AFAR and the participating foundations intend the short-term research training program to: o expose medical students, early in their training, to the excitement of ongoing research; o encourage medical students to consider pursuing, and to plan for over time, either a basic science, health services, or clinical research career in the areas of research that are important to the NIA; o increase the pool of physician scientists engaged in biomedical, clinical or health services research in those areas necessary to continue the mission of the NIA. The key building blocks of the program will be a series of related Institutional National Research Service Award (NRSA) grants (T35) which will each provide support for training experiences of eight to twelve consecutive weeks under the supervision of experienced researchers. The program should contain a mix of didactic activities and research experiences appropriate to the level and interests of the participating student class. The program will also support students’ travel to the American Geriatrics Society (AGS) annual scientific meeting, to participate in an AGS/AFAR student poster session and roundtable luncheon, where students meet with peers and mentors in aging-related research and academic geriatrics. NIA and the foundations have strong interests in continuing to diversify the research workforce committed to advancing the fields of aging and geriatric research. Therefore, applicants are strongly encouraged to make efforts to recruit medical students from diverse backgrounds for these short-term training experiences. Students who are members of ethnic or racial groups underrepresented in these fields and students with disabilities are important targets for these extra recruitment efforts. Others whose background and experience is likely to diversify the research questions being addressed or medical conditions explored are also appropriate targets for these efforts. Such students may include, for example, those from economically disadvantaged backgrounds or those with extensive experience in different cultures. In carrying out their stewardship of human resource related programs, NIA or the participating foundations may request information essential to assess the effectiveness of this program. Accordingly, you are hereby notified that you may be contacted for periodic updates on various aspects of the students’ follow-up activities and career choices and other information helpful in evaluating the impact of the program. MECHANISM OF SUPPORT This RFA will use the National Institutes of Health (NIH) National Research Service Award (NRSA) Short-Term Training grant (T35) award mechanism. As an applicant, you will be solely responsible for planning, directing, and executing the proposed training program. This RFA is a one-time solicitation. Future unsolicited competing continuation applications based on this training program will compete with all other investigator-initiated applications and will be reviewed according to the customary review procedures. The anticipated award date is June 1, 2005. Applications that are not funded in this competition may be resubmitted as NEW applications using standard receipt dates for training grant applications described in the introduction to the PHS 398 form. FUNDS AVAILABLE NIA and the participating foundations intend to commit approximately $750,000 in FY 2005 to fund 4 to 6 new grants in response to this RFA. An applicant may request a project period of up to 5 years and a budget for direct costs of up to $130,000 per year. Because the nature and scope of the proposed research training will vary from application to application, it is anticipated that the size and duration of each award will also vary. Although the financial plans of NIA and the participating foundations provide support for this program, awards pursuant to this RFA are contingent upon the availability of funds and the receipt of a sufficient number of meritorious applications. ELIGIBLE INSTITUTIONS You may submit an application if your institution has any of the following characteristics: o Non-profit organizations o Public or private institutions, such as universities and colleges o Units of State and local governments o Eligible agencies of the Federal government o Domestic Institution o Foreign Institutions are not eligible to apply ELIGIBLE TRAINING PROGRAM DIRECTORS Individuals with the skills, knowledge, and resources necessary to organize and implement a high quality research training program are invited to work with their institutions as directors of research training programs in order to develop applications for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. The research training program director at the institution will be responsible for the selection and appointment of trainees to the NRSA research training grant and for the overall direction, management, and administration of the program. TRAINEE ELIGIBILITY REQUIREMENTS Trainees must have successfully completed at least one year, at a school of medicine or osteopathy, prior to participating in the program, and provide evidence of such likelihood at the time of application. These grants are intended to introduce students to research experiences that they would not otherwise normally complete while medical students. Trainees must be citizens or non-citizen nationals of the United States or must have been lawfully admitted for permanent residence (i.e., in possession of a currently valid Alien Registration Receipt Card I-551, or some other legal verification of such status). Non-citizen nationals are generally persons born in outlying possessions of the United States (e.g., American Samoa and Swains Island). Individuals on temporary or student visas and individuals holding Ph.D., M.D., D.V.M., or equivalent doctoral degrees in the health sciences are not eligible. SPECIAL REQUIREMENTS In a cover letter submitted with the application: (1) Awardees must agree to use a common electronic application process (to be developed by AFAR acting in conjunction with the awardees) to recruit students for the training awards. The form will require students to apply to a central site and indicate their preferences for different schools participating in the program. AFAR will make applications available on an internal web-site accessible only by awardees. In addition to contacting students directly awardees will use this site to indicate selection of candidates for the program. Students will use the site to accept or reject an offer from a particular program. AFAR will alert awardees to students who remain available for selection by the participating programs. (2) Awardees must agree to a schedule determined in advance by the group of awardees for initial offers of summer appointments and for final selection. (3) Awardees must agree to participate in American Geriatric Society events that involve summer student participants. WHERE TO SEND INQUIRIES We encourage your inquiries concerning this RFA and welcome the opportunity to answer questions from potential applicants. Inquiries may fall into three areas: scientific/research, peer review, and financial or grants management issues: o Direct your questions about scientific/research issues to: Robin A. Barr, D. Phil. Office of Extramural Affairs 7201 Wisconsin Avenue, Room 2C218, MSC 9205 Bethesda, MD 20892-9205 Telephone: (301) 496-9322 FAX: (301) 402-2945 Email: BarrR@nia.nih.gov o Direct your questions concerning peer review issues to: Mary Nekola, Ph.D. Chief, Scientific Review Office National Institute on Aging Gateway Building, Suite 2C212 Bethesda, MD 20892-2292 Telephone: (301) 496-9666 FAX: (301) 402-0066 Email: email@example.com o Direct your questions about financial or grants management matters to: Linda Whipp Grants Management Officer National Institute on Aging Gateway Building, Suite 2N212 Bethesda, MD 20892-2292 Telephone: (301) 496-1472 FAX: (301) 402-3672 Email: whippL@nia.nih.gov LETTER OF INTENT Prospective applicants are asked to submit a letter of intent that includes the following information: o Descriptive title of the proposed research training program o Name, address, and telephone number of the Principal Investigator o Names of other key personnel o Participating institutions o Number and title of this RFA Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review. The letter of intent is to be sent by the date listed at the beginning of this document. The letter of intent should be sent to: Mary Nekola, Ph.D. Chief, Scientific Review Office National Institute on Aging Gateway Building, Suite 2C212 Bethesda, MD 20892-2292 Telephone: (301) 496-9666 FAX: (301) 402-0066 Email: firstname.lastname@example.org SUBMITTING AN APPLICATION Applications must be prepared using the PHS 398 research grant application instructions and forms (rev. 5/2001). Applications must have a DUN and Bradstreet (D&B) Data Universal Numbering System (DUNS) number as the Universal Identifier when applying for Federal grants or cooperative agreements. The D&B number can be obtained by calling (866) 705-5711 or through the web site at http://www.dunandbradstreet.com/. The D&B number should be entered on line 11 of the face page of the PHS 398 form. The PHS 398 document is available at http://grants.nih.gov/grants/funding/phs398/phs398.html in an interactive format. For further assistance contact GrantsInfo, Telephone (301) 435-0714, Email: GrantsInfo@nih.gov. This initiative is a collaboration among NIA and the participating foundations. On receipt of your application NIA staff will contact you to seek your permission to share the application and the results of the review with the collaborating partners. NIA and the participating foundations will jointly consider the applications to determine responsiveness to the RFA (see below under PEER REVIEW PROCESS) and jointly consider the results of review in order to develop a funding plan (see below under AWARD CRITERIA). SUPPLEMENTARY INSTRUCTIONS Institutions may request support for up to 18 trainees per year, based on a full-time, three month appointment. A trainee must be appointed for a minimum of two months (8 weeks) and a maximum of three months (12 weeks) during a budget period. Students may apply to participate in the program for more than one year, i.e., during two or more consecutive summers. All research training must be full-time during the specified training period. It is expected that programs will provide a summer research training program. The requested number of funded short-term training slots must be justified in the application based on the magnitude and focus of the research supported at the applicant and other co-applicant institutions, with particular attention to the areas of research supported by the NIA, and to the interest of qualified investigators who will serve as training faculty, research mentors and role models. Students should be able to pursue basic, clinical or health services research projects in the broad areas of geriatrics and gerontology. Applications must describe a plan for didactic instruction of the students as well as mentored research experiences. The research experiences should be ones that are tailored to permit clear progress in the course of the short-term training offered. Ideally the experiences should be planned to allow the students’ a role in a presentation or abstract. The didactic instruction should include training in the responsible conduct of research (see below). Faculty who will be mentors for the students must be identified in the application together with biographical information reflecting their prior experience in similar programs. Applications may request support to recruit students who choose to stay at their current medical school and receive mentoring and instruction from researchers at that school. Applicants should include the list of schools considered eligible to participate in this outreach instruction and identify faculty at these schools who have agreed to serve as mentors. Biographical information that includes the mentoring history of participating faculty at outreach schools should be submitted as part of the application. If such outreach schools are part of the application then applicants may consider including one or two weeks of didactic instruction at the host school (including training in the responsible conduct of research) to provide a common orientation. Additional funds may be requested to cover travel and accommodation of outreach students during this training. Where an applicant anticipates that some students will remain at the distal school throughout the training period the application should describe the arrangements that have been made to ensure a shared training experience and training in the responsible conduct of research. Funds may be requested for: o Stipends – The FY04 stipend level for trainees is $1731 per month. The stipend level actually awarded will be that in effect for predoctoral trainees at the time the award is issued. Stipends may be supplemented from non-Federal funds, however, under no circumstances may the conditions of the supplementation interfere with, detract from or prolong the participant’s NRSA supported training program. One use of supplemental funding could be to provide housing expenses, as needed, for student participants from another medical school. A Statement of Appointment form (PHS 2271, rev. 4/98) must be submitted at the start of each trainee appointment and reappointment. This form is available at the following URL address: http://grants.nih.gov/training/phs2271.pdf. Trainees supported under this program are not required to sign an NRSA Payback Agreement; however, they must submit an NRSA Termination Notice. o Training-related Expenses The foundations will provide up to $15,000 annually for faculty, laboratory, and technical assistance; supplies and equipment; consultant costs; and fees. Applicants should request these funds as part of the application and justify the request in the budget by identifying the kinds of activities and personnel to be supported with the additional funds. In addition, NIA will provide the current institutional allowance for trainees. In FY 2004 that amount is $183 per month per trainee. No part of these funds may be used to pay for secretarial or other kinds of administrative and clerical support. Accepted applicants may apply, on an annual basis, directly to AFAR for supplemental funding for programmatic expenses. Available funds will vary from year to year, and are not guaranteed. o Travel Expenses – Through application to AFAR in the appropriate award years, the institution may request up to $1,000 per year per trainee to help defray the cost of travel to a relevant scientific meeting. The meeting should normally be the annual meeting of the American Geriatrics Society where events are planned particularly for trainees from this program. The foundations will supply the funds that allow student travel. The meeting will typically be held in the year following the budget period in which the student participates in his/her research training, particularly for students attending the AGS annual scientific meeting, which is held in May. The institution may additionally seek up to $1,000 per year per trainee to cover travel and accommodation for any students at distal sites to travel to the central training institution for one or two-week courses. Institutions should estimate these costs in the initial application based on the anticipated number of students to be recruited from distal locations. NIA will pay these expenses. Every NRSA trainee supported by an institutional training grant must receive instruction in the Responsible Conduct of Research (For more information on this provision, see the current announcement for NRSA Intuitional Research training grants [T32] published in the NIH Guide for Grants and Contracts[PA-02-109; Release Date: May 16, 2002] or at the following URL address: http://grants.nih.gov/grants/guide/pa-files/PA-02-109.html USING THE RFA LABEL: The RFA label available in the PHS 398 (rev. 5/2001) application form must be affixed to the bottom of the face page of the application. Type the RFA number on the label. Failure to use this label could result in delayed processing of the application such that it may not reach the review committee in time for review. In addition, the RFA title and number must be typed on line 2 of the face page of the application form and the YES box must be marked. The RFA label is also available at: http://grants.nih.gov/grants/funding/phs398/labels.pdf. SENDING AN APPLICATION TO THE NIH: Submit a signed, typewritten original of the application, including the Checklist, and three signed, photocopies, in one package to: Center for Scientific Review National Institutes of Health 6701 Rockledge Drive, Room 1040 Bethesda, MD 20892-7710 Bethesda, MD 20817 (for express/courier service) At the time of submission, two additional copies of the application and all copies of the appendix material must be sent to: Mary Nekola, Ph.D., Chief Scientific Review Office National Institute on Aging Gateway Building, Room 2C212 Bethesda, MD 20892-9205 For express/courier service use Bethesda MD 20814 Telephone: (301) 496-9666 FAX: (301)402-0066 Email: email@example.com APPLICATION PROCESSING: Applications must be received on or before the application receipt date listed in the heading of this RFA. If an application is received after that date, it will be returned to the applicant without review. Although there is no immediate acknowledgement of the receipt of an application, applicants are generally notified of the review and funding assignment within 8 weeks. The Center for Scientific Review (CSR) will not accept any application in response to this RFA that is essentially the same as one currently pending initial review, unless the applicant withdraws the pending application. However, when a previously unfunded application, originally submitted as an investigator-initiated application, is to be submitted in response to an RFA, it is to be prepared as a NEW application. That is, the application for the RFA must not include an Introduction describing the changes and improvements made, and the text must not be marked to indicate the changes from the previous unfunded version of the application. PEER REVIEW PROCESS Upon receipt, applications will be reviewed for completeness by the CSR and responsiveness by NIA and the participating foundations. Incomplete and nonresponsive applications will not be reviewed. Applications that are complete and responsive to the RFA will be evaluated for scientific and technical merit by an appropriate peer review group convened by NIA in accordance with the review criteria stated below. As part of the initial merit review, all applications will: o Undergo a process in which only those applications deemed to have the highest scientific merit, generally the top half of the applications under review, will be discussed and assigned a priority score o Receive a written critique o Receive a second level review by the National Advisory Council on Aging REVIEW CRITERIA The following criteria will be considered when evaluating the applications: o the objectives and design of the research, and didactic training program components; the degree to which the research experiences and training are appropriately tailored to medical students and to the duration of their expected training. o the plan to recruit students at the host institution and/or nationally and to seek out those from diverse backgrounds who may enrich the learning experiences of the group or influence the research questions being addressed. o quality of the applicant pool at the host institution and other included sites. This assessment will include consideration of the diversity of the applicant pool and of efforts to include students from diverse backgrounds in the applicant pool. o the qualifications of the program director and the participating preceptors as basic, clinical, and health services researchers, including publications and successful competition for research support in the fields of aging and geriatrics; o past training record of both the program director and the designated preceptors; o the institutional training environment, including the institutional commitment to training students in basic and clinical research, quality of the facilities, availability of appropriate courses and seminars, and the availability of research support; o (where applicants propose to include students located at distal campuses) the quality of the research environment available to students away from the host campus; the availability of appropriately qualified local faculty to work with students directly; the degree to which the host institution works to integrate the distal students into any shared learning experiences of students based on the main campus. o the institution’s plan to measure the effectiveness of the overall training program, including the productivity of the trainees (e.g., abstracts, presentations, publications); any differences among trainees based on where they receive their training (at the host institution or at distal sites); the impact of the program on the institution; and the impact of the program on the career choices, opportunities, and further research activities of the trainees. The review group will also comment on each application’s plan for training in the responsible conduct of research. PROTECTION OF HUMAN SUBJECTS FROM RESEARCH RISK: The involvement of human subjects and protections from research risk relating to their participation in the proposed research will be assessed. (See criteria included in the section on Federal Citations, below). http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.htm INCLUSION OF WOMEN, AND MINORITIES IN RESEARCH: The adequacy of plans to include subjects from both genders, and all racial and ethnic groups (and subgroups), as appropriate for the scientific goals of the research will be assessed. Plans for the recruitment and retention of subjects will also be evaluated. (See Inclusion Criteria in the sections on Federal Citations, below). CARE AND USE OF VERTEBRATE ANIMALS IN RESEARCH: If vertebrate animals are to be used in the project, the five items described under Section f of the PHS 398 research grant application instructions (rev. 5/2001) will be assessed. BUDGET: The reasonableness of the proposed budget and the requested period of support in relation to the proposed research training. RECEIPT AND REVIEW SCHEDULE Letter of Intent Receipt Date: October 18, 2004 Application Receipt Date: November 18, 2004 Peer Review Date: March 2005 Council Review: May 2005 Earliest Anticipated Start Date: June 2005 AWARD CRITERIA Award criteria that will be used by NIA and the participating foundations to make funding decisions are: o Quality of the proposed training program as determined by peer review; o Availability of funds; o Program priority, i.e., how focused on NIA research areas is the proposed training. REQUIRED FEDERAL CITATIONS ANIMAL WELFARE PROTECTION: Recipients of PHS support for activities involving live, vertebrate animals must comply with PHS Policy on Humane Care and Use of Laboratory Animals (http://grants.nih.gov/grants/olaw/references/PHSPolicyLabAnimals.pdf), as mandated by the Health Research Extension Act of 1985 (http://grants.nih.gov/grants/olaw/references/hrea1985.htm), and the USDA Animal Welfare Regulations (http://www.nal.usda.gov/awic/legislat/usdaleg1.htm), as applicable. HUMAN SUBJECTS PROTECTION: Federal regulations (45CFR46) require that applications and proposals involving human subjects must be evaluated with reference to the risks to the subjects, the adequacy of protection against these risks, the potential benefits of the research to the subjects and others, and the importance of the knowledge gained or to be gained. http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.htm INCLUSION OF WOMEN AND MINORITIES IN CLINICAL RESEARCH: It is the policy of the NIH that women and members of minority groups and their sub-populations must be included in all NIH-supported clinical research projects unless a clear and compelling justification is provided indicating that inclusion is inappropriate with respect to the health of the subjects or the purpose of the research. This policy results from the NIH Revitalization Act of 1993 (Section 492B of Public Law 103-43). All investigators proposing clinical research should read the "NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical Research - Amended, October, 2001," published in the NIH Guide for Grants and Contracts on October 9, 2001 (http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-001.html); a complete copy of the updated Guidelines are available at http://grants.nih.gov/grants/funding/women_min/guidelines_amended_10_2001.htm. The amended policy incorporates: the use of an NIH definition of clinical research; updated racial and ethnic categories in compliance with the new OMB standards; clarification of language governing NIH-defined Phase III clinical trials consistent with the new PHS Form 398; and updated roles and responsibilities of NIH staff and the extramural community. The policy continues to require for all NIH- defined Phase III clinical trials that: a) all applications or proposals and/or protocols must provide a description of plans to conduct analyses, as appropriate, to address differences by sex/gender and/or racial/ethnic groups, including subgroups if applicable; and b) investigators must report annual accrual and progress in conducting analyses, as appropriate, by sex/gender and/or racial/ethnic group differences. REQUIRED EDUCATION ON THE PROTECTION OF HUMAN SUBJECT PARTICIPANTS: NIH policy requires education on the protection of human subject participants for all investigators submitting NIH proposals for research involving human subjects. You will find this policy announcement in the NIH Guide for Grants and Contracts Announcement, dated June 5, 2000, at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-039.html. HUMAN EMBRYONIC STEM CELLS (hESC): Criteria for federal funding of research on hESCs can be found at http://stemcells.nih.gov/index.asp and at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-005.html. Only research using hESC lines that are registered in the NIH Human Embryonic Stem Cell Registry will be eligible for Federal funding (see http://escr.nih.gov). It is the responsibility of the applicant to provide, in the project description and elsewhere in the application as appropriate, the official NIH identifier(s) for the hESC line(s) to be used in the proposed research. Applications that do not provide this information will be returned without review. PUBLIC ACCESS TO RESEARCH DATA THROUGH THE FREEDOM OF INFORMATION ACT: The Office of Management and Budget (OMB) Circular A-110 has been revised to provide public access to research data through the Freedom of Information Act (FOIA) under some circumstances. Data that are (1) first produced in a project that is supported in whole or in part with Federal funds and (2) cited publicly and officially by a Federal agency in support of an action that has the force and effect of law (i.e., a regulation) may be accessed through FOIA. It is important for applicants to understand the basic scope of this amendment. NIH has provided guidance at http://grants.nih.gov/grants/policy/a110/a110_guidance_dec1999.htm. Applicants may wish to place data collected under this RFA in a public archive, which can provide protections for the data and manage the distribution for an indefinite period of time. If so, the application should include a description of the archiving plan in the study design and include information about this in the budget justification section of the application. In addition, applicants should think about how to structure informed consent statements and other human subjects procedures given the potential for wider use of data collected under this award. STANDARDS FOR PRIVACY OF INDIVIDUALLY IDENTIFIABLE HEALTH INFORMATION: The Department of Health and Human Services (DHHS) issued final modification to the “Standards for Privacy of Individually Identifiable Health Information”, the “Privacy Rule,” on August 14, 2002. The Privacy Rule is a federal regulation under the Health Insurance Portability and Accountability Act (HIPAA) of 1996 that governs the protection of individually identifiable health information, and is administered and enforced by the DHHS Office for Civil Rights (OCR). Decisions about applicability and implementation of the Privacy Rule reside with the researcher and his/her institution. The OCR website (http://www.hhs.gov/ocr/) provides information on the Privacy Rule, including a complete Regulation Text and a set of decision tools on “Am I a covered entity?” Information on the impact of the HIPAA Privacy Rule on NIH processes involving the review, funding, and progress monitoring of grants, cooperative agreements, and research contracts can be found at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-03-025.html. URLs IN NIH GRANT APPLICATIONS OR APPENDICES: All applications and proposals for NIH funding must be self-contained within specified page limitations. Unless otherwise specified in an NIH solicitation, Internet addresses (URLs) should not be used to provide information necessary to the review because reviewers are under no obligation to view the Internet sites. Furthermore, we caution reviewers that their anonymity may be compromised when they directly access an Internet site. HEALTHY PEOPLE 2010: The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2010," a PHS-led national activity for setting priority areas. This RFA is related to one or more of the priority areas. Potential applicants may obtain a copy of "Healthy People 2010" at http://www.healthypeople.gov/. AUTHORITY AND REGULATIONS: This program is described in the Catalog of Federal Domestic Assistance at http://www.cfda.gov/ and is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review. Awards are made under the authorization of Section 487 of the Public Health Service Act as amended (42 USC 288) and under Federal Regulations 42 CFR 66 and. All awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement. The NIH Grants Policy Statement can be found at http://grants.nih.gov/grants/policy/policy.htm The PHS strongly encourages all grant recipients to provide a smoke-free workplace and discourage the use of all tobacco products. In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care, or early childhood development services are provided to children. This is consistent with the PHS mission to protect and advance the physical and mental health of the American people.
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