EXPIRED
RESEARCH TO STRENGTHEN OCCUPATIONAL SAFETY AND HEALTH SURVEILLANCE Release Date: February 28, 2000 RFA: OH-00-005 National Institute for Occupational Safety and Health Letter of Intent Date: March 24, 2000 Application Receipt Date: April 28, 2000 THIS RFA USES THE "MODULAR GRANT" AND "JUST-IN-TIME" CONCEPTS. IT INCLUDES DETAILED MODIFICATIONS TO STANDARD APPLICATION INSTRUCTIONS THAT MUST BE USED WHEN PREPARING APPLICATIONS IN RESPONSE TO THIS RFA. PURPOSE The Centers for Disease Control and Prevention (CDC) announces the availability of fiscal year (FY) 2000 funds for grant applications for research to strengthen occupational safety and health surveillance. Projects are sought that (1) strengthen surveillance of high-risk industries and occupations, such as mining, and of populations at higher risk; (2) promote a better understanding of the magnitude and scope of childhood agricultural injuries and illnesses; (3) develop methods for effective occupational safety and health surveillance conducted by employers, unions, and other non-governmental organizations; and (4) increase research methods development to improve occupational surveillance. A common issue for such projects is the critical need to include in the study design consideration of under-recognition and under-reporting of workplace illness and injury. Findings from these projects are intended to advance the scientific base of knowledge needed to monitor occupational safety and health hazards, injuries and illnesses. The research needs identified in this announcement are consistent with the National Occupational Research Agenda (NORA) developed by NIOSH and partners in the public and private sectors to provide a framework to guide occupational safety and health research in the new millennium towards topics which are most pressing and most likely to yield gains to the worker and the nation. The agenda identifies 21 research priorities. NORA priorities with specific relevance to this announcement are: surveillance research methods, traumatic injuries and special populations at risk. Information about NORA is available through the NIOSH Home Page; http://www.cdc.gov/niosh/norhmpg.html. HEALTHY PEOPLE 2010 CDC is committed to achieving the health promotion and disease prevention objectives of AHealthy People 2010,@ a national activity to reduce morbidity and mortality and improve the quality of life. This announcement is related to the focus area of occupational safety and health. For information on the conference on AHealthy People 2010,@ visit the internet site: http://www.health.gov/healthypeople. ELIGIBILITY REQUIREMENTS Applications may be submitted by domestic and foreign, public and private nonprofit and for-profit organizations and by governments and their agencies; that is, universities, colleges, research institutions, hospitals, other public and private nonprofit and for-profit organizations, State and local governments or their bona fide agents, and federally recognized Indian tribal governments, Indian tribes, or Indian tribal organizations. Note: Public Law 104-65 states that an organization described in section 501(c)(4) of the Internal Revenue Code of 1986 which engages in lobbying activities is not eligible to receive Federal funds constituting an award, grant (cooperative agreement), contract, loan, or any other form. FUNDS AVAILABLE Approximately $1,500,000 is available in fiscal year (FY) 2000 to fund 7-10 research project grants under this RFA. Approximately $500,000 of this amount is planned for research grants specific to childhood agricultural injuries and illnesses. Approximately $250,000 of this amount is planned for research grants specific to mine health and safety. Awards are anticipated to range from $150,000 to $250,000 in total costs (direct and indirect) per year. A higher budget may be requested, but only if the applicant first corresponds with program staff (see contact in the INQUIRIES section) and receives written approval prior to the submission deadline. Applicants should include in their budgets funds for one trip per year for an annual meeting of grantees to be held in Washington, DC. Awards will be made for a 12-month budget period within a project period up to 3 years. However, if well justified, project periods up to four years may be requested. Continuation awards within the project period will be made on the basis of satisfactory progress and availability of funds in future years. Awards are expected to begin in August 2000. Only applications that are found to be of high scientific merit will be considered for funding, and not all of the funds will be spent if there are not enough highly meritorious applications. The mechanism of support will be the individual research project grant (R01). The total requested project period for an application submitted in response to this RFA should be three to four years based on the scope of the project. Specific application instructions have been modified to reflect "MODULAR GRANT" and "JUST-IN-TIME" streamlining efforts (see BUDGET INSTRUCTIONS). The modular grant concept establishes specific modules in which direct costs may be requested as well as a maximum level for requested budgets. Only limited budgetary information is required under this approach. The just-in-time concept allows applicants to submit certain information only when there is a possibility for an award. It is anticipated that these changes will reduce the administrative burden for the applicants, reviewers and Institute staff. Complete and detailed instructions and information on Modular Grants can be found at http://grants.nih.gov/grants/funding/modular/modular.htm. Applications will request direct costs in $25,000 modules, up to a direct cost request of $250,000 per year. However, for this RFA the total cost requested may not exceed $250,000 per year (see "FUNDS AVAILABLE" for guidance on budget). A typical modular grant application will request the same number of modules in each year. Application budgets will be simplified. Detailed categorical budget information will not be submitted with the application; budget form pages of the application kits will not be used. Instead, total direct costs requested for each year will be presented. Information, in narrative form, will be provided only for Personnel and, when applicable, for Consortium/Contractual Costs. See section on APPLICATION PROCEDURES below. Additional narrative budget justification will be required in the application only if there is a variation in the number of modules requested. There will be no routine escalation for future years. In determining the total for each budget year, applicants should first consider the direct cost of the entire project period. Well-justified modular increments or decrements in the total direct costs for any year of the project that reflect substantial changes in expected future activities may be requested. For example, purchase of major equipment in the first year may justify a higher overall budget in the first, but not in succeeding years. AOther Support@ pages of the PHS 398 will not be submitted with the application. Information on research projects ongoing or completed during the last three years of the principal investigator and key personnel will be provided as part of the "Biographical Sketch." This information will include the specific aims, overall goals and responsibilities and should include Federal and non-Federal support. This information will be used by reviewers in the assessment of each individuals qualifications for a specific role in the proposed project. Following peer review, information about AOther Research Support@ will be requested from the applicant for applications being considered for award. Additional budget information will be requested only under special circumstances. This RFA is a one-time announcement. Future unsolicited competing continuation applications will compete with all investigator-initiated applications and be reviewed according to the customary peer review procedures. Responsibility for the planning, direction, and execution of the proposed project will be solely that of the applicant. RESEARCH OBJECTIVES Background Occupational safety and health surveillance refers to the ongoing, systematic collection, analysis, and interpretation of relevant health and hazard data essential to the planning, implementing, and evaluation of industrial safety, industrial hygiene, occupational health, and/or public health practice, closely integrated with the timely dissemination of these data to those who need to know. The final link of the surveillance chain is the application of these data to prevention and control. A surveillance system includes a functional capacity for data collection, analysis, and dissemination linked to industrial safety, industrial hygiene, occupational health, and/or public health programs. Surveillance systems can operate at one or more work organization or geo-political levels (e.g. plan, company, union, state or federal levels). Occupational safety and health surveillance research refers to the development and demonstration of models for new or improved occupational data collection, surveillance methods, models, or surveillance systems. Surveillance research can focus on any link of the surveillance chain (e.g. from research on a single data component of an existing or potential surveillance system to developing and/or evaluating a complete surveillance system or set of systems). The final link, in both the research process and surveillance chain, is the publication and dissemination of findings to those who have a need to know. Research Goals The NIOSH Surveillance Strategic Plan, developed by NIOSH with substantial input from its partners in the public and private sectors, outlines a framework to promote and support the development and evaluation of surveillance and surveillance- related research methods. Several general and specific research needs identified in the NIOSH Surveillance Strategic Planning process are targeted in this RFA: (1) strengthen surveillance of high-risk industries and occupations, and of populations at higher risk, including special populations; (2) promote a better understanding of the magnitude and scope of childhood agricultural injuries and illnesses; (3) develop effective occupational safety and health surveillance conducted by employers, unions, and other non-governmental organizations; and (4) increase research methods development to improve occupational surveillance. A common research issue hindering the development of surveillance systems and surveillance-related research is the lack of proven approaches for addressing the problems of under-recognition and under- reporting of workplace illness and injury. Data from NIOSH, academic and other researchers have shown that certain populations of workers are at especially high risk for occupational illness, injury, and hazard. Individuals employed in agriculture, construction, and mining still account for a large burden of occupational illness and injury. Health care workers, representing a growing industrial sector, have increasing rates of nonfatal injuries and illnesses, as well as increased hazardous exposures to such things as blood-borne pathogens, latex, and biomechanical stress. Other groups of workers are at increased risk because of age, gender, race, disability, or genetic susceptibility. There is a specific need for new surveillance methods to better understand the magnitude and scope of childhood agricultural injuries and illnesses, target prevention efforts, and assess progress over time. Such new methods should include ways of collecting data on one or more groups at risk (youth farm workers, the children of farm workers and farm operators, children of migrant and seasonal farm workers, and children visiting farm operations) and should provide a means for collecting data that encompass injuries and illnesses associated with occupational and non-occupational exposures. While no single surveillance method can capture all populations of interest, it is important that focused surveillance research methods be developed that can address the multiple issues relevant to children and agriculture. New/modified surveillance methods to reach migrant and seasonal workers are especially needed. Occupational surveillance activities often exist in the private sector apart from Federal and State surveillance programs. Occupational surveillance is conducted by employers, unions, health professionals and institutions, and others using various methods to track illnesses, injuries, and hazards for the purpose of prevention and control activities. Innovation and the development of new approaches to surveillance in the private sector need to be encouraged and supported. In addition, empirical evaluations of the impact of occupational surveillance in the private sector on worker safety, health, and productivity are needed in order to recommend and encourage Abest practices.@ Research is needed to evaluate existing systems and approaches for conducting surveillance. The National Occupational Research Agenda (NORA) Surveillance Research Methods team has begun efforts to increase the level of research to improve occupational surveillance. Numerous potential sources of occupational health and safety data exist, but these have neither been fully evaluated nor utilized for surveillance purposes. The use of nontraditional data sources and linkages of data systems are virtually unexplored. Traditional sources of data for occupational illness and injury surveillance may exclude certain workers due to their employment status, or size of an employer (e.g., workers in small businesses and self-employed, part-time, seasonal or migrant workers). Current surveillance research methods do not adequately capture these population groups, and as a result effective intervention strategies to reduce the occupational health burden have been slow to develop. Surveillance is a critical component of the public health approach and worksite prevention efforts, providing empirical information to target and develop effective research and prevention measures. Methodologic research to ensure that surveillance efforts are conducted efficiently and result in valid and generalizable data are necessary to ensure appropriate use of resources and targeting of research and prevention efforts. As well, research is needed to identify means of gathering information on Ahard to reach@ populations that are frequently missed in existing surveillance efforts, and the collection of information that can best guide prevention efforts generically and for high risk groups. Thus the goals for this RFA are to foster the development of surveillance research methods that 1. Strengthen surveillance methods for high-risk industries and occupations, and of populations at higher risk, including special populations; 2. Provide a better understanding of the magnitude and scope of childhood agricultural injuries and illnesses; 3. Promote effective occupational safety and health surveillance conducted by employers, unions, and other non-governmental organizations; and 4. Increase research to improve occupational surveillance. The following illustrate some but not all of the topics that are appropriate for this RFA: HIGH RISK INDUSTRIES, OCCUPATIONS, AND SPECIAL POPULATIONS Develop methods/approaches for identifying chemical, physical, and biological agents as well as the job tasks which should be part of surveillance efforts because they may place workers in minority populations at excess risk for occupational morbidity and mortality. Develop methods to augment existing surveillance systems to identify and follow-up the occupational problems associated with traditionally under served populations. Traditional sources of data for occupational illness and injury surveillance may exclude certain workers due to their employment status, or size of an employer (e.g., contract workers, workers in small businesses and self-employed, part-time, seasonal or migrant workers). Develop methods to document the health and safety experience of the growing numbers of special populations (e.g., young, older, people of color, disabled and genetic susceptible employees) in the workforce. Develop and test the validity and reliability of hazard surveillance methods in high risk industries and occupations, such as agriculture, construction, and mining. CHILDHOOD AGRICULTURAL INJURIES AND ILLNESSES Develop and test methods to measure childrens' exposure to physical hazards, toxic chemicals or ergonomic hazards in agricultural production activities and the farm environment. Develop and test new/modified methods to address under-reporting and under-representation of childhood agricultural injuries and illnesses in standard injury databases, such as vital statistics reporting systems, emergency department systems, workers' compensation systems, and employer and population surveys. Develop new/modified survey methods and approaches (e.g. telephone, mail, in-person) for assessing childhood agricultural injuries and illnesses of children. Develop new innovative methods for surveillance of agricultural injuries and illnesses among migrant and minority children. Develop methods to assess the social and economic burden of childhood agricultural injuries and illnesses. MINE INJURIES AND ILLNESSES Develop and test methods to measure miner's exposure to physical hazards, toxic chemicals or ergonomic hazards. Develop and test new/modified methods to address under-reporting and under-representation of mining injuries and illnesses in standard injury databases, such as vital statistics reporting systems, emergency department systems, workers' compensation systems, and employer and population surveys. Develop new/modified survey methods and approaches (e.g. telephone, mail, in-person) for assessing injuries and illnesses of miners. Develop new innovative methods for surveillance of injuries and illnesses among miners. Develop methods to assess the social and economic burden of mining injuries and illnesses. RESEARCH METHODS FOCUSED ON THE SAFETY AND HEALTH SURVEILLANCE BY EMPLOYERS, UNIONS, AND OTHER NON-GOVERNMENTAL ORGANIZATIONS Develop and assess surveillance methods that promote effective prevention of workplace illnesses and/or injuries through earlier recognition of individual cases and/or earlier recognition of patterns of illnesses or injuries indicating the need for preventive intervention. Approaches should consider the cost effectiveness of a method. Develop and assess innovative new methods for routine monitoring of workplace safety and health hazards/exposures that are intended for use by employers, unions, health professionals and institutions, or other non-governmental entities. (e.g., monitoring required by existing regulations; special surveys of trade or union groups; etc.). Such methods could include surveillance based on monitoring positive, planned preventive activities. Develop and validate approaches to describe the social and economic burden of occupational illnesses and/or injuries at a plant-level, company-level, union-level, or industry level, including direct and indirect costs and effects on quality of life. RESEARCH TO IMPROVE OCCUPATIONAL SURVEILLANCE Develop methods to evaluate the prevalence of and estimate the impact of under-recognition and under-reporting of workplace illness and injury. Develop new/modified approaches for conducting surveys of households, trade or union groups that allows comparison to data collected by other mechanisms. Develop approaches for integrating occupational safety and health elements into existing/evolving public health or information systems. Development of methods for evaluating extant data (e.g. workers' compensation data, private insurance data, employer data) for the purpose of creating priority setting models that can be used to help set priorities for surveillance and prevention efforts at the regional, state or local level. Develop methods to improve estimating the "population-at-risk" for surveillance of illness and injury of long latency Develop methods for estimating "exposure time" for machine use hazards and other time-dependent injury risks. Develop methods for effective exposure monitoring, medical screening, and disease and injury surveillance of worker populations at risk for important work-related conditions and injuries, such as musculoskeletal disorders, irritant contact dermatitis, asthma, pesticide poisoning, hearing loss, bladder cancer, heat stress, and radiation effects. Develop methods to evaluate and monitor workplace hazards, exposures, illness, injury, and related-risk factors among small scale businesses, independent contractors, service sector part- time or occasional labor, and vulnerable (e.g., workers less than 16 years or the legal age of consent, and migrant labor) working populations. Develop methods to link existing surveillance systems in a state, to better estimate the magnitude of occupational injuries and illnesses in a state, and to assess the degree of overlap between different systems and most efficient means of surveillance. SPECIAL REQUIREMENTS Annual Meetings for Investigators Principal Investigators for projects funded though this RFA should plan to attend an annual meeting for grantees and NIOSH staff. The first meeting is planned for Cincinnati, Ohio in early November, 2000. These meetings will afford grantees and NIOSH staff an opportunity to interact and share information about their projects, the study designs and approaches being used, and discuss problems and solutions that have been identified. Funds for travel to the annual meeting for the principal investigator and other senior investigators involved in the project should be included in the budget. Human Subjects If a project involves research on human subjects, assurance (in accordance with Department of Health and Human Services Regulations, 45 CFR Part 46) of the protection of human subjects is required. In addition to other applicable committees, Indian Health Service (IHS) institutional review committees also must review the project if any component of IHS will be involved with or will support the research. If any American Indian community is involved, its tribal government must also approve that portion of the project applicable to it. Unless the grantee holds a Multiple Project Assurance, a Single Project Assurance is required, as well as an assurance for each subcontractor or cooperating institution that has immediate responsibility for human subjects. The Office for Protection from Research Risks (OPRR) at the National Institutes of Health (NIH) negotiates assurances for all activities involving human subjects that are supported by the Department of Health and Human Services. INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS It is the policy of the Centers for Disease Control and Prevention (CDC) to ensure that individuals of both sexes and the various racial and ethnic groups will be included in CDC-supported research projects involving human subjects, whenever feasible and appropriate. Racial and ethnic groups are those defined in OMB Directive No. 15 and include American Indian or Alaska Native, Asian, Black or African American, Hispanic or Latino, Native Hawaiian or Other Pacific Islander. Applicants shall ensure that women, racial and ethnic minority populations are appropriately represented in applications for research involving human subjects. Where clear and compelling rationale exist that inclusion is inappropriate or not feasible, this situation must be explained as part of the application. This policy does not apply to research studies when the investigator cannot control the race, ethnicity, and/or sex of subjects. Further guidance to this policy is contained in the Federal Register, Vol. 60, No. 179, pages 47947-47951, and dated Friday, September 15, 1995. INCLUSION OF CHILDREN AS PARTICIPANTS IN RESEARCH INVOLVING HUMAN SUBJECTS It is the policy of NIH that children (i.e., individuals under the age of 21) must be included in all human subjects research, conducted or supported by the NIH, unless there are scientific and ethical reasons not to include them. This policy applies to all initial (Type 1) applications submitted for receipt dates after October 1, 1998. All investigators proposing research involving human subjects should read the "NIH Policy and Guidelines on the Inclusion of Children as Participants in Research Involving Human Subjects" that was published in the NIH Guide for Grants and Contracts, March 6, 1998, and is available at the following URL address: http://grants.nih.gov/grants/guide/notice-files/not98-024.html. LETTER OF INTENT Prospective applicants are asked to submit, by March 24, 2000, a letter of intent that includes the number and title of the RFA, a descriptive title of the proposed research, the name, address, and telephone number of the Principal Investigator, and the identities of other key personnel and participating institutions. Although a letter of intent is not required, is not binding, and is not used in the review of an application, the information that it contains is used to estimate the potential review workload and avoid conflict of interest in the review. The letter of intent is to be submitted to: Ms. Ann Cronin Office of Extramural Programs National Institute for Occupational Safety and Health Centers for Disease Control and Prevention (CDC) 1600 Clifton Road, N.E. Building 1, Room 3070B, MS D-40 Atlanta, GA 30333 Telephone 404-639-2376; Fax 404-639-0035 Email: axc2@cdc.gov APPLICATION PROCEDURES Applicants must use Form PHS 398 (rev. 4/98). Application kits are available at most institutional offices of sponsored research and may be obtained from the Division of Extramural Outreach and Information Resources, National Institutes of Health, 6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910, telephone 301/710-0267, Email: grantsinfo@nih.gov. Application kits are also available at: http://grants.nih.gov/grants/forms.htm. BUDGET INSTRUCTIONS The total direct costs must be requested in accordance with the program guidelines and the modifications made to the standard PHS 398 application instructions described below: o FACE PAGE: Items 7a and 7b should be completed, indicating Direct Costs (in $25,000 increments up to a maximum of $250,000) and Total Costs [Modular Total Direct plus Facilities and Administrative (F&A) costs] for the initial budget period. (However, see "FUNDS AVAILABLE" for guidance on budget.) Items 8a and 8b should be completed indicating the Direct and Total Costs for the entire proposed period of support. o DETAILED BUDGET FOR THE INITIAL BUDGET PERIOD - Do not complete Form Page 4 of the PHS 398. It is not required and will not be accepted with the application. o BUDGET FOR THE ENTIRE PROPOSED PERIOD OF SUPPORT - Do not complete the categorical budget table on Form Page 5 of the PHS 398. It is not required and will not be accepted with the application. o NARRATIVE BUDGET JUSTIFICATION - Use a Modular Grant Budget Narrative page. (See http://grants.nih.gov/grants/funding/modular/modular.htm for sample pages.) At the top of the page, enter the total direct costs requested for each year. o Under Personnel, List key project personnel, including their names, percent of effort, and roles on the project. No individual salary information should be provided. For Consortium/Contractual costs, provide an estimate of total costs (direct plus facilities and administrative) for each year, each rounded to the nearest $1,000. List the individuals/organizations with whom consortium or contractual arrangements have been made, the percent effort of key personnel, and the role on the project. Indicate whether the collaborating institution is foreign or domestic. The total cost for a consortium/contractual arrangement is included in the overall requested modular direct cost amount. Provide an additional narrative budget justification for any variation in the number of modules requested. - BIOGRAPHICAL SKETCH - The Biographical Sketch provides information used by reviewers in the assessment of each individual's qualifications for a specific role in the proposed project, as well as to evaluate the overall qualifications of the research team. A biographical sketch is required for all key personnel, following the instructions below. No more than three pages may be used for each person. A sample biographical sketch may be viewed at: http://grants.nih.gov/grants/funding/modular/modular.htm - Complete the educational block at the top of the form page; - List current position(s) and then previous positions; - List selected peer-reviewed publications, with full citations; - Provide information, including overall goals and responsibilities, on research projects ongoing or completed during the last three years. - CHECKLIST - This page should be completed and submitted with the application. If the F&A rate agreement has been established, indicate the type of agreement and the date. It is important to identify all exclusions that were used in the calculation of the F&A costs for the initial budget period and all future budget years. - The applicant should provide the name and phone number of the individual to contact concerning fiscal and administrative issues if additional information is necessary following the initial review. Applications not conforming to these guidelines will be considered unresponsive to this RFA and will be returned without further review. The RFA label available in the PHS 398 application form must be affixed to the bottom of the face page of the application. Failure to use this label could result in delayed processing of the application such that it may not reach the review committee in time for review. In addition, the RFA title and number must be typed on line 2 of the face page of the application form and the YES box must be marked. The sample RFA label available at: http://grants.nih.gov/grants/funding/phs398/label-bk.pdf has been modified to allow for this change. Please note this is in pdf format. If the proposed project involves organizations or persons other than those affiliated with the applicant organization, letters of support and/or cooperation must be included. Submit a signed, typewritten original, including the checklist, and three signed, clear, and single sided photocopies in one package to: CENTER FOR SCIENTIFIC REVIEW NATIONAL INSTITUTES OF HEALTH 6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710 BETHESDA, MD 20892-7710 BETHESDA, MD 20817 (for express/courier service) At the time of submission, two additional copies of the application must also be sent to Ms. Ann Cronin at the address under LETTER OF INTENT. Applications must be received by April 28, 2000. If an application is received after that date, it will be returned to the applicant without review. The Center for Scientific Review (CSR) will not accept any application in response to this RFA that is essentially the same as one currently pending initial review, unless the applicant withdraws the pending application. The CSR will not accept any application that is essentially the same as one already reviewed. This does not preclude the submission of substantial revisions of applications already reviewed, but such applications must include an introduction addressing the previous critique. REVIEW CONSIDERATIONS Upon receipt, applications will be reviewed for completeness and responsiveness. Applicants should clearly indicate in the project Description (page 2 of application) which priority area of this RFA is being addressed by their proposal. Applications determined to be incomplete or unresponsive to this RFA will be returned to the applicant without further consideration. Applications that are complete and responsive to the RFA will be reviewed for technical merit by a scientific review group. Reviewers will identify those applications with the highest scientific merit, which generally comprise the top half of applications reviewed. Those applications will be discussed fully and assigned a priority score between 100 and 300 (100 is the best possible score). For all other applications, there will be a limited discussion and they will not be scored. Notification of the scientific review results will be sent to the applicants after the review. Following the scientific review, applications will receive a review for programmatic importance. Scientific Review Criteria o Significance - Does this study address an important problem related to the topical research issues outlined in this announcement? If the aims of the application are achieved, how will scientific knowledge be advanced? What will be the effect of these studies on the concepts or methods that drive this field? o Approach - Are the conceptual framework, design (including composition of study population), methods, and analyses adequately developed, well-integrated and appropriate to the aims of the project? Does the applicant acknowledge potential problem areas and consider alternative tactics? o Innovation - Does the project employ novel concepts, approaches or methods? Are the aims original and innovative? Does the project challenge existing paradigms or develop new methodologies or technologies? o Investigator - Is the investigator appropriately trained and well suited to carry out this work? Is the work proposed appropriate to the experience level of the principal investigator and other researchers, if any? o Environment - Does the scientific environment in which the work will be done contribute to the probability of success? Do the proposed experiments take advantage of unique features of the scientific environment or employ useful collaborative arrangements? Is there documentation of cooperation from industry, unions, or other participants in the project, where applicable? Is there evidence of institutional support and availability of resources necessary to perform the project? The scientific review group will also examine the appropriateness of proposed project budget and duration; the adequacy of plans to include both genders, minorities and their subgroups, and children as appropriate for the scientific goals of the research and plans for the recruitment and retention of subjects; the provisions for the protection of human and animal subjects; and the safety of the research environment. The personnel category will be reviewed for appropriate staffing based on the requested percent effort. The direct costs budget request will be reviewed for consistency with the proposed methods and specific aims. Any budgetary adjustments recommended by the reviewers will be in $25,000 modules. The duration of support will be reviewed to determine if it is appropriate to ensure successful completion of the requested scope of the project. Programmatic Review Criteria: o Magnitude of the problem in terms of numbers of workers affected. o Severity of the disease or injury in the worker population. o Likelihood of developing applied technical knowledge for the prevention of occupational safety and health hazards on a national or regional basis. AWARD CRITERIA Final funding decisions are based on the recommendations of the scientific and programmatic reviews, balance of awards across the areas of research goals of this RFA, and availability of funds. Awards are expected to begin in August 2000. INQUIRIES Inquiries concerning this RFA are encouraged. The opportunity to clarify any issues or questions from potential applicants is welcome. This RFA and other CDC Announcements can be found on the CDC homepage (http://www.cdc.gov) under the "Funding" section (see AGrants and Cooperative Agreements@ scroll down to AOccupational Safety and Health@). This RFA can also be found on the NIOSH Homepage (http://www.cdc.gov/niosh) under "Extramural Programs", "Current Funding Opportunities". Direct inquiries regarding programmatic issues to: Roy M. Fleming, Sc.D. Director, Research Grants Program National Institute for Occupational Safety and Health Centers for Disease Control and Prevention 1600 Clifton Road, N.E. Building 1, Room 3053, MS D-30 Atlanta, GA 30333 Telephone: 404/639-3343 FAX: 404/639-4616 Email: rmf2@cdc.gov Direct inquiries regarding grants management matters to: Joanne Wojcik CDC Announcement Number 00045 Grants Management Branch Procurement and Grants Office Centers for Disease Control and Prevention 2920 Brandywine Road, Suite 3000 Atlanta, GA 30341-4146 Telephone: 770/488-2717 FAX: 770/488-2777 Email: jcw6@cdc.gov LOBBYING RESTRICTIONS Applicants should be aware of restrictions on the use of HHS funds for lobbying of Federal or State legislative bodies. Under the provisions of 31 U.S.C. Section 1352, recipients (and their sub- tier contractors) are prohibited from using appropriated Federal funds (other than profits from a Federal contract) for lobbying congress or any Federal agency in connection with the award of a particular contract, grant, cooperative agreement, or loan. This includes grants/cooperative agreements that, in whole or in part, involve conferences for which Federal funds cannot be used directly or indirectly to encourage participants to lobby or to instruct participants on how to lobby. In addition no part of PHS appropriated funds, shall be used, other than for normal and recognized executive-legislative relationships, for publicity or propaganda purposes, for the preparation, distribution, or use of any kit, pamphlet, booklet, publication, radio, television, or video presentation designed to support or defeat legislation pending before the Congress or any State or local legislature, except in presentation to the Congress or any State or local legislature itself. No part of the appropriated funds shall be used to pay the salary or expenses of any grant or contract recipient, or agent acting for such recipient, related to any activity designed to influence legislation or appropriations pending before the Congress or any State or local legislature. AUTHORITY AND REGULATIONS The Catalog of Federal Domestic Assistance number is: 93.262 for the National Institute for Occupational Safety and Health (NIOSH). This program is authorized under the Public Health Service Act, as amended, Section 301(a) [42 U.S.C. 241(a)], and the Occupational Safety and Health Act of 1970, Section 20(a) [29 U.S.C. 669(a)]. The applicable program regulation is 42 CFR Part 52. SMOKE-FREE WORKPLACE CDC strongly encourages all grant recipients to provide a smoke-free workplace and promote the non-use of all tobacco products, and Public Law 103- 227, the Pro-Children Act of 1994, prohibits smoking in certain facilities that receive Federal funds in which education, library, day care, health care, and early childhood development services are provided to children.
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