SPECIALIZED NEUROSCIENCE RESEARCH PROGRAMS AT MINORITY INSTITUTIONS
 
Release Date:  May 14, 1998 (see NOT-NS-03-022)

RFA:  NS-99-001

P.T.

National Institute of Neurological Disorders and Stroke
National Center for Research Resources
Office of Research on Minority Health

Letter of Intent Receipt Date:  August 1, 1998
Application Receipt Date:  February 10, 1999

PURPOSE

The National Institute of Neurological Disorders and Stroke (NINDS), in
collaboration with the National Center for Research Resources (NCRR) and the
Office of Research on Minority Health (ORMH), invites applications for
Specialized Neuroscience Research Programs at Minority Institutions (SNRP)
awards.  The purpose of this Request for Applications (RFA) is to augment and
strengthen the research capabilities of faculty, students, and fellows at
minority institutions by supporting the development of new, and/or the
enhancement of ongoing, basic and clinical neuroscience research projects and
programs.

The National Institutes of Health (NIH) recognizes that minority institutions are
an integral component of our national biomedical research agenda.  Therefore, the
NIH is offering programmatic assistance for the development of the technology and
resources that are necessary to conduct state-of-the-art neuroscience research. 
The SNRP will help the awardee institutions prepare the next generation of
neuroscience investigators.  Beyond this, the SNRP will become regional resources
that contribute to the NIH mission to find new knowledge that will improve the
health of the American public.  This competitive RFA is one way that the NIH
identifies and supports neuroscientists at eligible institutions to conduct and
report the meritorious, preliminary research that will foster successful
competition for traditional research project grants (e.g., R-series, P-series
and/or equivalent NSF grants) during the performance period of the award.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health promotion
and disease prevention objectives of "Healthy People 2000," a PHS-led national
activity for setting priority areas.  This RFA, Specialized Neuroscience Research
Programs at Minority Institutions, is related to the priority areas of
neurological disorders and stroke.  Potential applicants may obtain a copy of
"Healthy People 2000" (Full Report:  Stock No. 017-001-00474-0 or Summary Report: 
Stock No. 017-001-00473-1) through the Superintendent of Documents, Government
Printing Office, Washington, DC 20402-9325 (Telephone 202-512-1800).

ELIGIBILITY REQUIREMENTS

Applications will only be accepted from domestic, public or private, non-profit,
academic institutions that offer Ph.D., M.D., and/or equivalent health
professional degrees, at which more than 50 percent of the students enrolled are
from cultural or racial minority groups.  Each applicant institution must
identify a collaborating institution that can be a domestic Federal or
non-Federal, public or private, non-profit organization.  Because the awardee
will need continuous and substantial research collaborations to achieve the
objectives of this RFA, the collaborating organization must be in the U.S., its
possessions, or its territories.

The principal investigator, who serves as SNRP Director, must be a U.S. citizen,
permanent resident, or non-citizen national.  An award pursuant to this RFA will
not be made until and unless the institution appoints a Program Director who is
a neuroscientist and has the professional skills needed to direct the Program. 
(The administrative leadership skills, quality of independent neuroscience
research, research productivity, and ability to obtain and effectively use
research support of the proposed Program Director will be assessed.  See REVIEW
CONSIDERATIONS)

Participating applicant investigators should have completed two or more years of
postdoctoral neuroscience research and must be full-time employees of the
applicant institution.  Participating collaborating investigators must be NIH
and/or NSF grantees who are currently supported by R-series, P-series and/or
equivalent NSF grant awards in the Neurosciences.  (See RESEARCH OBJECTIVES)

MECHANISM OF SUPPORT

The Cooperative Agreement (U-series) award is the administrative mechanism for
supporting activities in which the NIH collaborates substantially in scientific
and/or programmatic matters with the awardee institution(s).  The Specialized
Center-Cooperative Agreement (U54) mechanism will be used to support the SNRP
award.  It is anticipated that collaborating neuroscientists will benefit from
a broader range of research resources and interdisciplinary research approaches
than are available at any one institution.  An SNRP award will support research
and research development activities within the scope of the program priorities
identified by the NINDS, NCRR, and ORMH.

The NIH will support and stimulate the activities of the awardee(s) by working
as a partner.  The NIH will not assume direction, take primary responsibility,
or in any other way dominate the activity.  The section TERMS AND CONDITIONS
contains detailed descriptions of the responsibilities, relationships, and
governance of the activities supported by the cooperative agreements for the
Specialized Neuroscience Research Programs at Minority Institutions.

FUNDS AVAILABLE

The NINDS, NCRR, and ORMH plan to make up to three SNRP awards in Fiscal Year
1999.  An applicant may request a project period of five or fewer years and a
budget for direct costs of up to $1,000,000 per year, excluding indirect costs
on consortium arrangements.  Because the nature and scope of the research
proposed may vary, it is anticipated that the size of each award will also vary. 
Although the financial plans of the NINDS, NCRR, and ORMH provide support for
this program, awards pursuant to this RFA are contingent upon the availability
of funds and the receipt of applications of outstanding scientific and technical
merit.  At this time, it is not known if competing renewal applications will be
accepted and/or if this RFA will be reissued.

Applicants planning to submit an investigator-initiated new (type 1), competing
continuation (type 2), competing supplement, or any amended/revised version of
the preceding grant application types requesting $500,000 or more in direct costs
for any year are advised that he or she must contact Institute or Center (IC)
program staff before submitting the application, i.e., as plans for the study are
being developed.  Furthermore, the applicant must obtain agreement from IC staff
that the IC will accept the application for consideration for award.  Finally,
the applicant must identify, in a cover letter sent with the application, the
staff member and Institute or Center who agreed to accept assignment of the
application.  This policy requires an applicant to obtain agreement for
acceptance of both any such application and any subsequent amendment.  Refer to
the NIH Guide for Grants and Contracts, March 20, 1998.

Any application subject to this policy that does not contain the required
information in a cover letter sent with the application will be returned to the
applicant without review.

RESEARCH OBJECTIVES

Background

The NINDS, NCRR, and ORMH want to foster an improved health status of and
eliminate the health care disparity experienced by minority Americans.  Focused
research and research career development programs such as the Specialized
Neuroscience Research Programs at Minority Institutions are used to achieve those
objectives.  Secondly, the NIH recognizes the contributions that minority
institutions can make to fulfilling the promise of the NIH research agenda are
unique and essential.  Therefore, the NIH has the responsibility to the Nation
to ensure that minority and other 'non-research-intensive' institutions can
develop the technology and other resources needed to conduct significant
neuroscience research.  Thirdly, the NIH, by means of the Specialized
Neuroscience Research Programs at Minority Institutions and other programs, can
foster the collaborative research affiliations needed to address neuroscience
research problems relevant to the communities and regions served by the SNRP
awardee institutions.

The Specialized Neuroscience Research Programs at Minority Institutions will
strive to meet the following programmatic goals:  (1) to help minority
institutions develop state-of-the-art neuroscience research programs; (2) to
create more opportunities for researchers employed by minority institutions to
establish research collaborations and professional networks with NIH and/or NSF
grantees employed by research intensive institutions; (3) to increase the role
of ongoing research in maintaining a vigorous, stimulating academic and
intellectual milieu that will inspire and prepare students and fellows to pursue
research careers in neuroscience; and (4) to provide support for the pilot
research needed to show the skills and abilities of investigators by obtaining
the preliminary data and publications that can help ensure successful competition
for traditional research project grants during the performance period of the
award.

Research Areas

The NINDS is a leading supporter of scientific investigations into the causes,
prevention, diagnosis, and treatment of neurological disorders and stroke.  An
application for a Specialized Neuroscience Research Program at a Minority
Institution could include proposals for basic and/or clinical research in the
following specific areas:

o  stroke and other cerebrovascular diseases and disorders;
o  episodic neurological states, such as epilepsy, chronobiology, circadian
rhythms, and sleep;
o  demyelinating and immunologically-mediated disorders of the nervous system;
o  neuro-AIDS and other viral-associated diseases of the nervous system;
o  neuromuscular and peripheral nerve disorders;
o  fundamental neural processes, neuroprothesis and pain;
o  neurodegenerative diseases and disorders;
o  trauma and injury to the nervous system; and
o  neurogenetics, neuroendocrinology, and nervous system development.

The research plan of an application for a SNRP award must contain the description
of up to three multidisciplinary, collaborative, research projects that will be
mutually beneficial to participating investigators through coordinated,
cooperative interactions.  Each of the proposed projects should effectively use
the scientific and technical strengths of collaborating investigators to define
a research plan appropriate to the requested duration  that will advance
scientific knowledge in the research areas identified above.

Description of Key Elements in an Application for a Specialized Neuroscience
Research Program Award

These are the key elements for the Specialized Neuroscience Research Program:

o  Selection and appointment of an SNRP Director who has had experience with
neuroscience research funding and research training;

o  Selection of up to three highly qualified applicant investigators to propose
and direct meritorious research projects suited to their neuroscience research
expertise.  These investigators are required to devote a minimum of 50 percent
research effort to their respective projects;

o  Documentation of the nature and scope of the collaborative research projects
with NIH grantees from research intensive institutions.  Collaborating
investigators must devote a minimum of 20 percent research effort to their
respective projects;

o  Evidence that the senior leadership at the applicant institution has addressed
issues such as tenure, promotion, research release time, and other personnel
matters pertaining to the scientific success of the SNRP Director and applicant
investigators.  Documentation/evidence of institutional commitment and the
availability of technical resources and facilities for the long-term support of
the SNRP.  Features of the institutional environment that are relevant to
effective accomplishment of the overall neuroscience program must be briefly
described.  As appropriate, available resources (e.g., clinical and laboratory
facilities, patient populations, geographic distributions of space and personnel)
and collaborative resources should be described.  A letter of support from a
senior institution official (e.g., President or Dean) should outline the
commitment for resources and facilities to sustain and support the neuroscience
program throughout the period of funding and beyond the performance period of
this award;

o  The applicant must identify and outline plans for support staff (e.g., grants
management, administrative, and technical) to ensure the timely ordering of
research supplies, equipment, and other resources essential to the scientific
productivity of the research award;

o  Eligible institutions must show evidence of an existing research
infrastructure that can support the neuroscience research program.  Previous
(past five years) and current research support used for neuroscience research
should be described.  The existing research infrastructure and needed
enhancements must be delineated;

o  Briefly describe how the proposed activities will enhance the scientific
capabilities of faculty, students and fellows in neuroscience, and strengthen the
neuroscience curriculum; and

o  Define the chain of responsibility for decision making and administration,
beginning at the level of the institution's President and including all key staff
(e.g., Sponsored Programs Administrator, Department Chair, and Dean).  Describe
the plans for day-to-day administration of the SNRP, including program
coordination, planning, and evaluation.  Describe the proposed relationship of
SNRP to existing programs and, in detail, how the SNRP initiative will augment
and strengthen the research infrastructure.

SPECIAL REQUIREMENTS

The awardee will work to establish research priorities within the approved
research scope of each SNRP award through discussions with the NINDS Special
Initiatives and Developmental Programs Officer (NINDS-SIDPO).  The NINDS reserves
the right to include outside consultants/experts in these discussions.  After the
awardee and the NINDS-SIDPO have set the priorities, the awardee will be
responsible for conducting the research activities.  The awardee and the
NINDS-SIDPO will interact in a cooperative manner throughout the duration of the
award to facilitate progress and resolve any problems that may arise.  Other NIH
program staff from the NCRR Director for Research Infrastructure (NCRR-DRI) and
ORMH may participate in establishing research priorities throughout the
performance period of the SNRP award.

TERMS AND CONDITIONS

The following Terms of Award are in addition to, and not instead of, otherwise
applicable OMB administrative guidelines, HHS Grant Administration Regulations
at 45 CFR Part 74 and 92, and other HHS, PHS, and NIH grant administration
policies.  Cooperative Agreements are subject to the administrative requirements
outlined in pertinent OMB, HHS, PHS, and NIH guidelines, with particular emphasis
on HHS regulations at 42 CFR Part 52 and 45 CFR Part 74.  Indirect costs are
calculated and awarded for cooperative agreement awards the same as for grants.

1.  The Awardee Rights and Responsibilities:

o  The awardee has primary authority and responsibility to define the scientific
objectives and approaches, to plan, conduct, analyze, and publish results,
interpretations, and conclusions of the studies;

o  The awardee has the primary responsibility for establishing effective and
substantial research collaborations with NIH and/or NSF grantees.  The scope and
nature of research on common protocols must be adequately documented and must
ensure participation, collaboration, and sharing of methods and data among
collaborating organizations;

o  The awardee has the primary responsibility for establishing an internal
advisory committee of the collaborating neuroscientists.  The committee will have
the responsibility for directing and monitoring the progress of the research
projects.  Beyond this, the committee must develop opportunities for information
exchange, seminar presentations, and research training opportunities for students
and fellows;

o  The awardee has the primary responsibility for establishing an external
advisory committee of distinguished senior neuroscientists.  Annually, the
committee will assess the productivity of the SNRP, make recommendations for the
future direction of the SNRP initiative, and provide advice and guidance about
personnel matters and the allocation of resources to individual projects and
investigators.

The awardee will retain custody of and primary rights to the data and
intellectual property developed under the award, subject to current government
policies regarding rights of access as consistent with current HHS, PHS, and NIH
policies.  The NINDS reserves the right to negotiate additional awardee terms and
conditions based on recommendations from the Initial Review Group, the National
Advisory Research Resources Council, the ORMH Advisory Committee, and the
National Advisory Neurological Disorders and Stroke Council.

2.  NINDS-SIDPO and NCRR-DRI Staff Responsibilities:

The NINDS-SIDPO and NCRR-DRI will have substantial scientific/programmatic
involvement during the award performance period by contributing to planning and
assessment activities, providing technical assistance, advice and coordination
beyond normal program stewardship for grants. (See INQUIRIES, below).

o  The NINDS-SIDPO will have primary responsibility for stewardship of the award
and overall responsibility for monitoring the conduct, progress, and fiscal
management of the research program.  The NCRR-DRI will provide advice and
guidance as appropriate;

o  The NINDS-SIDPO will help shape a comprehensive framework for the development
of the SNRP and provide technical advice and expertise regarding scientific
direction and program management.  The NCRR-DRI will provide advice and guidance
as appropriate;

o  The NINDS-SIDPO and NCRR-DRI will help the applicant institution and SNRP
Director establish reasonable time lines to achieve the developmental goals of
the SNRP.  The NINDS-SIDPO will facilitate interactions between the awardee and
collaborating investigators.  The NCRR-DRI will use programmatic authority within
the Research Center for Minority Institutions (RCMI) Program to assist in the
sharing of research resources and infrastructure for SNRP awards at
RCMI-supported institutions;

o  The NINDS-SIDPO and NCRR-DRI will reserve the authority to recommend
reductions in budget, withhold support, suspend and/or terminate the award if
technical performance falls below acceptable standards for quality and
timeliness;

o  The NINDS-SIDPO and NCRR-DRI will actively participate as non-voting members
in all meetings of the external advisory committee during the performance period
of the award;

o  The NINDS-SIDPO will have the authority to recommend additional research
endeavors within the approved research and negotiated budgets.  The NCRR-DRI will
provide advice and guidance as appropriate; and

o  The NINDS-SIDPO reserves the right to include selected extramural and
intramural staff as consultants/experts on scientific issues during the
performance period of the award.

3.  Arbitration

Any disagreements about scientific/programmatic matters (within the scope of the
award) between the awardee, the NINDS, NCRR and ORMH may be brought to an
arbitration panel convened by the Director's of the co-sponsoring NIH components.
The decision of the arbitration panel, by majority vote, will be binding.  The
process to resolve programmatic differences described above in no way affects the
rights of a recipient of a cooperative agreement assistance grant to appeal an
adverse determination in accordance with PHS regulations at 42 CFR Part 50,
Subpart D, and HHS regulations at 45 CFR Part 16.

INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS

It is the policy of the NIH that women and members of minority groups and their
sub-populations must be included in all NIH supported biomedical and behavioral
research projects involving human subjects, unless a clear and compelling
rationale and justification is provided that inclusion is inappropriate with
respect to the health of the subjects or the purpose of the research.  Adequate
plans to include both genders and minorities and their subgroups as appropriate
for the scientific goals of the research must be included.  Plans for recruitment
and retention of subjects will be evaluated.  This policy results from the NIH
Revitalization Act of 1993 (Section 492B of Public Law 103-43).

All investigators proposing research involving human subjects should read the NIH
Guidelines for Inclusion of Women and Minorities as Subjects in Clinical
Research, which have been published in the Federal Register of March 28, 1994 (FR
59 14508-14513) and in the NIH Guide for Grants and Contracts, Volume 23, Number
11, March 18, 1994.  This information is available on the Internet at
http://grants.nih.gov/grants/guide/notice-files/not94-100.html.

Investigators also may obtain copies of the policy from the program staff listed
under INQUIRIES.  Program staff may also provide additional relevant information
concerning the policy.

NIH POLICY AND GUIDELINES ON THE INCLUSION OF CHILDREN AS PARTICIPANTS IN
RESEARCH INVOLVING HUMAN SUBJECTS

It is the policy of NIH that children (i.e., individuals under the age of 21)
must be included in all human subjects research, conducted or supported by the
NIH, unless there is scientific or ethical reasons not to include them.  This
applies to all initial (Type 1) applications submitted for receipt dates after
October 1, 1998.

All investigators proposing research involving human subjects should read the
"NIH Policy and Guidelines on the inclusion of Children as Participants in
Research Involving Human Subjects" that was published in the NIH Guide for Grants
and Contracts, March 6, 1998, and is available at the following URL address:
http://grants.nih.gov/grants/guide/notice-files/not98-024.html

LETTER OF INTENT

Prospective applicants are asked to submit, by August 1, 1998, a letter of intent
that includes a descriptive title of the proposed research, the name, address,
and telephone number of the principal investigator, the identities of other key
personnel and participating institutions, and the number and title of the RFA in
response to which the application may be submitted.  Although a letter of intent
is not required, is not binding, and does not enter into the review of a
subsequent application, the information that it contains allows NINDS staff to
estimate the potential review workload and avoid conflict of interest in the
review.

The letter of intent is to be sent to:

Dr. Alfred W. Gordon
Special Initiatives and Developmental Programs Office
National Institute of Neurological Disorders and Stroke
7550 Wisconsin Avenue, Room 9C10
Bethesda, MD  20892
Email:  ag38x@nih.gov

APPLICATION PROCEDURES

The research grant application form PHS 398 (rev. 5/95) is to be used in applying
for these grants.  These forms are available at most institutional offices of
sponsored research and may be obtained from the Division of Extramural Outreach
and Information Resources, National Institutes of Health, 6701 Rockledge Drive,
MSC 7910, Bethesda, MD 20892-7910; telephone (301) 435-0714; Email:
grantsinfo@nih.gov; and from the NIH program administrator listed under
INQUIRIES.

An application for a SNRP award must include the following:

Competitive applications will develop new and/or strengthen existing
collaborative projects with NIH and or NSF grantees from research intensive
institutions.  Investigators must clearly define the nature and extent of the
research collaboration, such that they fully explain the necessary
administrative, fiscal, and scientific aspects in the application.

o  A research plan for up to five years that includes the proposed organization
and component functions of the SNRP.  The plan should demonstrate the applicant's
knowledge, ingenuity, practicality, and commitment to developing a significant,
productive, research program;

o  A description of and justification for the proposed individual research
projects and core service facilities.  Applicants are required to propose up to
three meritorious research projects, and must describe the nature and scope of
scientific research collaborations;

o  A description of the research and research training goals and capabilities of
the proposed SNRP.  The Program Director and NINDS-SIDPO must establish a time
line for supported applicant investigators to prepare and submit proposals for
traditional research grant review during the performance period of the SNRP
award; and

o  A description of the infrastructure for conducting studies aimed at developing
a nationally competitive neuroscience research program.

The RFA label, available in the PHS 398 (rev. 5/95) application kit, must be
affixed to the bottom of the face page of the application.  Failure to use this
label could result in delayed processing of the application such that it may not
reach the review committee in time for review.  In addition, the RFA number and
title must be typed on line 2 of the face page of the application form and the
"YES" box must be marked.

Submit a signed, typewritten original of the application, including the
Checklist, and three signed photocopies, in one package to:

CENTER FOR SCIENTIFIC REVIEW
NATIONAL INSTITUTES OF HEALTH
6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710
BETHESDA, MD  20892-7710
BETHESDA, MD  20817 (for express/courier service)

At the time of submission, two additional copies of the application must be sent
to:

Dr. Lillian Pubols
Scientific Review Branch
National Institute of Neurological Disorders and Stroke
7550 Wisconsin Avenue, Room 9C10
Bethesda, MD  20892

Schedule

Letter of Intent Receipt Date:  August 1, 1998
Application Receipt Date:       February 10, 1999
Council Review:                 September 1999
Earliest Award Date:            December 1, 1999

Applications must be received by February 10, 1999.  If an application is
received after that date, it will be returned to the applicant without review. 
The Center for Scientific Review (CSR) will not accept an application in response
to this RFA that is essentially the same as one currently pending initial review,
unless the applicant withdraws the pending application.  The CSR will not accept
any application that is essentially the same as one already reviewed.  This does
not preclude the submission of substantial revisions of applications already
reviewed, but such applications must include an introduction addressing the
previous critique.

REVIEW CONSIDERATIONS

Upon receipt, applications will be reviewed for completeness by CSR and
responsiveness by NINDS staff.  Applications that are incomplete and/or
non-responsive to this RFA, or exceed the maximum first year direct cost limit
of $1,000,000, excluding costs for consortium budgets, will be returned to the
applicant without further consideration.  A Special Emphasis Panel (SEP) convened
by the NINDS will determine the scientific merit of each application compared to
the other applications received in response to this RFA.  The NINDS will withdraw
from further competition those applications judged by the SEP to be
noncompetitive for an award and notify the applicant principal investigator and
applicant organization.

The review of the SNRP application is based not only on the traditional review
criteria for research projects, but also considers the feasibility and potential
for investigators to gain scientific independence.  The following criteria will
be used to evaluate the potential for productive collaborative research, and the
overall potential for enriching the academic and intellectual milieu for doing
research that will increase what is known about healthy and disordered nervous
systems.

o  The significance, approach, and innovation of the proposed research projects
and of the SNRP as a whole;

o  The scientific and administrative qualifications of the principal investigator
to direct the SNRP;

o  The strengths of the applicant investigators and collaborating
neuroscientists, particularly the academic qualifications, neuroscience research
experience, expertise and research productivity;

o  Appropriateness and adequacy of the experimental approach and methodology
proposed to carry out the research, considering the applicant and collaborator
research backgrounds and their respective contributions in the development of the
research proposal.  The application must have scientific merit, but unlike a
traditional research grant application, it must be evaluated in the context of
the developmental goals and feasibility of the study;

o  The nature, scope, and effectiveness of the plans for coordination and
cooperation among research project investigators;

o  Evaluate the facilities, resources, and environment of the applicant
institution (including existing relevant equipment, animal, and/or computer
resources, and departmental or interdepartmental cooperation);

o  Evidence of a detailed plan for career development of students and fellows in
neuroscience research and other neuroscience related health professions;

o  The specific research goals to be accomplished, the hypotheses to be tested,
and the likelihood that applicant investigators will produce the publications and
preliminary data to be competitive for a traditional research grant during the
performance period of the award;

o  Appropriateness of the proposed budget and duration, including the
justification for requested items in terms of the aims and methods of the
proposed research studies;

o  For research involving human subjects, adequacy of plans to include both
genders and minorities and their subgroups as appropriate for the scientific
goals of the research.  Plans for the recruitment and retention of subjects will
also be evaluated.  Reviewers should assess the age-appropriate inclusion or
exclusion of children in the research project and evaluate the plans for
conducting the research in accord with the NIH guidelines on the inclusion of
children as participants in research involving human subjects; and

o  The adequacy of the proposed plan for animal welfare and biohazard safety in
the research environment.

AWARD CRITERIA

Funding decisions will be based on scientific and technical merit as determined
by the Initial Review Group, the National Advisory Research Resources Council,
the ORMH Advisory Committee, the National Advisory Neurological Disorders and
Stroke Council, program balance, and the availability of funds.

INQUIRIES

Inquiries concerning this RFA are encouraged.  The opportunity to clarify any
issues or questions from potential applicants is welcome.

Direct inquiries regarding programmatic issues to:

Dr. Alfred W. Gordon
Special Initiatives and Developmental Programs Office
National Institute of Neurological Disorders and Stroke
7550 Wisconsin Avenue, Room 9C10
Bethesda, MD  20892
Telephone:  (301) 496-9223
FAX:  (301) 402-0182
Email:  ag38x@nih.gov

Dr. Sidney A. McNairy, Jr.
Research Infrastructure
National Center for Research Resources
6705 Rockledge Drive, Room 6136
Bethesda, MD  20892
Telephone:  (301) 435-0788
FAX:  (301) 480-3770
Email:  sm68k@nih.gov

For information on budget and fiscal matters, contact:

Maurice Johnson
Grants Management Branch
National Institute of Neurological Disorders and Stroke
7550 Wisconsin Avenue, Room 1004
Bethesda, MD  20892
Telephone:  (301) 496-9231
FAX:  (301) 402-0219
Email:  mj34w@nih.gov

AUTHORITY AND REGULATIONS

This program is described in the Catalog of Federal Domestic Assistance No.
93.854 (Biological Basis Research in the Neurosciences).  Awards are made under
authorization of the Public Health Service Act, Title IV, Part A (Public Law
78-410, as amended by Public Law 99-158, 42 USC 241 and 285) and administered
under PHS grants policies and Federal Regulation 42 CFR 52 and 45 CFR Part 74. 
This program is not subject to the intergovernmental review requirements of
Executive Order 12372 or Health Systems Agency review.

The PHS strongly encourages all grant and contract recipients to provide a smoke-
free workplace and promote the non-use of all tobacco products.  In addition,
Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain
facilities (or in some cases, any portion of a facility) in which regular or
routine education, library, day care, health care or early childhood development
services are provided to children.  This is consistent with the PHS mission to
protect and advance the physical and mental health of the American people.


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