and Human Services (HHS)
EXPIRED
Participating Organization(s) |
National Institutes of Health (NIH) |
NIH Basic Behavioral and Social Science Opportunity Network (OppNet; http://oppnet.nih.gov/) and its member institutes, centers and offices: National Cancer Institute (NCI) |
|
Funding Opportunity Title |
Sleep and Social Environment: Basic Biopsychosocial Processes (R21) |
Activity Code |
R21 Exploratory/Developmental Research Grant Award |
Announcement Type |
Reissue of RFA-HD-11-102 |
Related Notices |
None |
Funding Opportunity Announcement (FOA) Number |
RFA-HD-12-204 |
Companion FOA |
None |
Catalog of Federal Domestic Assistance (CFDA) Number(s) |
93.113, 93.121, 93.142, 93.143, 93.172,93.173, 93.213, 93.233, 93.242, 93.273 ,93.279 ,93.286 ,93.307, 93.361, 93.389,93.393, 93.394, 93.395,93.396, 93.399, 93.837, 93.838, 93.846, 93.847, 93.853, 93.855, 93.856, 93.859, 93.865, 93.866, 93.867, 93.879, 93.989 |
FOA Purpose |
This funding opportunity announcement (FOA) issued by the Basic Behavioral and Social Sciences Research Opportunity Network (OppNet), National Institutes of Health (NIH), solicits Research Project Grant (R21) applications from institutions/organizations that propose to investigate the reciprocal interactions of the processes of sleep and circadian regulation and function with behavioral and social environment processes. Sleep is a complex biological phenomenon that is essential to normal behavioral and social functioning, as well as optimal health. In spite of its vital nature, the mechanisms by which social environment factors affect sleep behavior patterns have not been studied systematically, especially within the context of individual vulnerabilities and resilience. There is a need for greater understanding of the dynamic relationships between behavioral and social environment factors on the one hand and the basic mechanisms of sleep-wake and circadian regulation and function on the other. This FOA is not intended to support research on or development of treatments or interventions for disorders of sleep or circadian rhythms.. |
Posted Date |
July 18, 2011 |
Open Date (Earliest Submission Date) |
August 30, 2011 |
Letter of Intent Due Date |
August 30, 2011 |
Application Due Date(s) |
September 30, 2011, by 5:00 PM local time of applicant organization. |
AIDS Application Due Date(s) |
Not Applicable |
Scientific Merit Review |
February/March 2012 |
Advisory Council Review |
May 2012 |
Earliest Start Date(s) |
July 2012 |
Expiration Date |
October 1, 2011 |
Due Dates for E.O. 12372 |
Not Applicable |
Required Application Instructions
It is critical that applicants follow the instructions in the SF 424 (R&R) Application Guide except where instructed to do otherwise (in this FOA or in a Notice from the NIH Guide for Grants and Contracts). Conformance to all requirements (both in the Application Guide and the FOA) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.
Part 1. Overview Information
Part 2. Full Text of the Announcement
Section I. Funding Opportunity Description
Section II. Award Information
Section III. Eligibility Information
Section IV. Application and Submission
Information
Section V. Application Review Information
Section VI. Award Administration Information
Section VII. Agency Contacts
Section VIII. Other Information
This FOA issued by the Basic Behavioral and Social Sciences Research Opportunity Network (OppNet), National Institutes of Health, solicits Research Project Grant (R21) applications from institutions/organizations that propose to investigate the reciprocal interactions of the processes of sleep and circadian regulation and function with behavioral and social environment processes. Sleep is a complex biological phenomenon that is essential to normal behavioral and social functioning, as well as optimal health. In spite of its vital nature, the mechanisms by which social environment factors affect sleep behavior patterns have not been studied systematically, especially within the context of individual vulnerabilities and resilience. There is a need for greater understanding of the dynamic relationships between behavioral and social environment factors on the one hand and the basic mechanisms of sleep-wake and circadian regulation and function on the other. This FOA is not intended to support research on or development of treatments or interventions for disorders of sleep or circadian rhythms.
OppNet is a trans-NIH initiative that funds activities that build the collective body of knowledge about the nature of behavior and social systems, and that deepen our understanding of basic mechanisms of behavioral and social processes. All 24 NIH Institutes and Centers that fund research and four Program Offices within the NIH Office of the Director (ICOs) co-fund and co-manage OppNet. All OppNet initiatives invite investigators to propose innovative research that will advance a targeted domain of basic social and behavioral sciences and produce knowledge and/or tools of potential relevance to multiple domains of health- and lifecourse-related research. Applicants should understand that the NIH IC that made this FOA available to the public is not necessarily the NIH Institute or Center that ultimately will manage a funded OppNet project. For more information about OppNet and all its funding opportunities, visit http://oppnet.nih.gov.
OppNet uses the NIH definition of basic behavioral and social science research (b-BSSR, http://obssr.od.nih.gov/about_obssr/BSSR_CC/BSSR_definition/definition.aspx) to determine application responsiveness. Consequently, OppNet strongly encourages prospective investigators to consult this definition, OppNet s answers to frequently asked questions about b-BSSR (http://oppnet.nih.gov/about-faqs.asp), and answers to frequently asked questions regarding this specific FOA (use this segment and insert website, if applicable). See this FOA’s Scientific Contacts section for individuals with expertise in the research subject matter and the OppNet initiative.
Sleep is a complex biological phenomenon that is essential to normal behavioral and social functioning, as well as optimal health. In spite of sleep’s vital nature, the mechanisms by which influences in the social environment affect sleep behavior patterns have not been studied systematically, particularly within the context of individual vulnerability, resilience, and adaptation. Trends over time in the U.S. and other developed countries show significant competition between sleep duration and timing and increasing demands and high reward activities. As with other behaviors (e.g., eating, exercise), individuals make daily decisions regarding when and how much to sleep in the context of other social activities, environmental demands, and psychophysiological drives. The nature of these decisions varies depending on the circumstances. When individuals experience a conflict between sleep and necessary activities (e.g., work, child care, assisting other dependent family members) they may be forced to sleep less. In contrast, when faced with desired activities (such as television viewing, gambling, or partying), the choice to sleep less is optional. Such disruptions in sleep patterns subsequently influence basic sleep-wake regulation and circadian regulation, and other time- and state-linked biological processes. For example, exposure to artificial light sources, eating, timing of ingestion of prescription medications and/or illicit drugs, and social behavior all impact circadian regulation (the timing of the sleep phase) and addictive or high reward activities (e.g., gaming, social networking, 24 hour access to electronic news and entertainment media) may increasingly account for the changes in the ratio of wake-to-sleep time.
Chronic and acute sleep loss and sleeping outside of the optimal circadian phase can result in persistent alterations in behavior and mechanisms regulating behavior. Investigators have established connections between disrupted circadian regulation, disordered sleep, and neuropsychiatric disorders as well as changes in metabolic regulation, inflammation, and immune response. Furthermore, mutations in genes involved in regulation of circadian rhythms have been shown to have effects on behavioral outcomes including cognition (e.g., learning and memory), addictive behavior, and mood (e.g., aggression). It is not known how choosing not to sleep in favor of engaging in optional activities for enjoyment may affect the rewards expected to be derived from these activities. Alterations in social systems and social learning and behavior are also generated by altered sleep processes, such as sleep deprived parents who exhibit less sensitivity and lower frustration tolerance to their infants. Broader consequences of less than optimal sleep include safety incidents and traffic fatalities. Among the most dramatic of consequences, the loss of the Space Shuttle Challenger has been attributed partly to impaired decision making and group think arising from sleep deprivation among the NASA engineer team.
This OppNet FOA provides a unique opportunity to link social environment factors that shape sleep behaviors with the direct neurobehavioral and circadian biology effects of sleep processes on individuals (both men and women) in the context of their social milieu. The research gap to be addressed lies between the understanding of the behavioral choices of individuals and social units, such as families and work groups, that determine sleep and circadian regulation (e.g., 24/7 media content, artificial light exposure, self imposed sleep debt) and individual susceptibility to decrements in neurobehavioral and social functioning arising from phenotypic, genotypic, and gene by environment interactions. Possible differential effects of so-called forced choices not to sleep due to overriding responsibilities (such as parenting) versus optional choices (such as partying) are unknown. Applicants are encouraged to develop theoretical models that capture social and behavioral interactions associated with sleep disturbance in social environments, including residential, employment, and school settings, while simultaneously incorporating biobehavioral markers of high and low susceptibility to sleep debt.
This FOA is intended to stimulate research that will investigate the biopsychosocial mechanisms underlying the reciprocal and dynamic relationships between behavioral and social environment factors on the one hand and basic sleep and circadian regulation and function on the other. Two broad categories of applications are responsive to this initiative: 1. Human or animal studies of the biological sequelae of changes in basic behavioral patterns of sleep duration and timing as a function of determinants from the social environment; 2. Human or animal studies of the dynamic relationships of individuals behaviors in social interactions as a function of sleep or circadian rhythms. These studies may have implications with broad social significance or more localized implications for individual health related behavior. Individuals experience and understand their environments as they perceive it through sensory input, and therefore this initiative encourages the incorporation of sensory mechanisms where appropriate to the science proposed.
This initiative is naturally suited to the emerging area of multilevel systems science approaches. One of the most important features of complex adaptive systems is that they include dynamic feedback, and multilevel research incorporates interactions between levels of aggregation and analysis. Among the factors involved in sleep and circadian regulation and function are underlying biological and neurobiological processes which are likely subject to gene-environment interaction processes. These in turn may define phenotypes in humans or animals that exhibit varying levels of resilience or vulnerability to effects on sleep and circadian disregulation. Dependent variables of these studies could include specific decrements in the functioning of behavioral mechanisms or micro- or macro-level social systems.
Finally, researchers are encouraged to take a developmental and gendered approach by considering variation across age and the life span and by sex/gender. Biological patterns of sleep and circadian regulation change naturally from infancy through the stages of childhood and adolescence and into early adulthood, and then again across adulthood and into old age. An individual’s experience of the social environment and behavioral patterns surrounding sleep may follow broader patterns by sex/gender. At minimum, researchers should take the life stage and sex/gender of the participants into account when proposing their causal theoretical models. Studies of mismatch in these patterns across members of a given social group may provide unique insights into biopsychosocial processes, if appropriate to the science proposed.
Appropriate topics include, but are not limited to, those listed below:
Studying the underlying mechanisms of behavioral and social environmental dynamics that affect individual choices for sleep and their subsequent consequences for circadian biology, such as:
Mechanisms of sleep and circadian biology that lead to variation in individual behavior and cumulate in altered social environments, such as:
Studies using animal models to evaluate the influences of altered circadian rhythms and/or sleep on social behavior and the molecular and genetic mechanisms involved, such as:
Studies using animal models to analyze the effects of disruptions in social behavior on sleep and circadian rhythms and investigation of the underlying genetic and neurochemical mechanisms, such as:
See Section VIII, Other Information - Required Federal Citations, for policies related to this announcement.
Funding Instrument |
Grant |
Application Types Allowed |
New The OER Glossary and the SF 424 (R&R) Application Guide provide details on these application types. |
Funds Available and Anticipated Number of Awards |
The number of awards is contingent upon NIH appropriations, and the submission of a sufficient number of meritorious applications. OppNet intends to fund an estimate of 4-5 awards, corresponding to a total of $1,000,000, for fiscal year 2012. Future year amounts will depend on annual appropriations. |
Award Budget |
The total project period for an application submitted in response to this FOA may not exceed two years. Direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 in direct costs allowed in any single year. |
Award Project Period |
The total project period for an application submitted in response to this FOA is 2 years. |
NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made in response to this FOA.
Higher Education Institutions
The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
Nonprofits Other Than Institutions of Higher Education
For-Profit Organizations
Governments
Other
Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to
apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Applicant organizations must complete the following registrations
as described in the SF 424 (R&R) Application Guide to be eligible to apply
for or receive an award. Applicants must have a valid Dun and Bradstreet
Universal Numbering System (DUNS) number in order to begin each of the following
registrations.
All Program Directors/Principal Investigators (PD/PIs) must
also work with their institutional officials to register with the eRA Commons
or ensure their existing eRA Commons account is affiliated with the eRA Commons
account of the applicant organization.
All registrations must be completed by the application due date. Applicant organizations
are strongly encouraged to start the registration process at least four (4)
weeks prior to the application due date.
Any individual(s) with the skills, knowledge, and resources
necessary to carry out the proposed research as the Program Director/Principal
Investigator (PD/PI) is invited to work with his/her organization to develop an
application for support. Individuals from underrepresented racial and ethnic
groups as well as individuals with disabilities are always encouraged to apply
for NIH support.
For institutions/organizations proposing multiple PDs/PIs, visit the Multiple
Program Director/Principal Investigator Policy and submission details in the Senior/Key
Person Profile (Expanded) Component of the SF 424 (R&R) Application Guide.
This FOA does not require cost sharing as defined in the NIH Grants Policy Statement.
Applicant organizations may submit more than one application, provided that each application is scientifically distinct.
NIH will not accept any application in response to this FOA that is essentially the same as one currently pending initial peer review unless the applicant withdraws the pending application. NIH will not accept any application that is essentially the same as one already reviewed. Resubmission applications may be submitted, according to the NIH Policy on Resubmission Applications from the SF 424 (R&R) Application Guide.
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the Apply for Grant Electronically button in this FOA or following the directions provided at Grants.gov.
It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide, except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
For information on Application Submission and Receipt, visit Frequently Asked Questions Application Guide, Electronic Submission of Grant Applications.
Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review.
By the date listed in Part 1. Overview Information, prospective applicants are asked to submit a letter of intent that includes the following information:
The letter of intent should be sent to:
Rosalind B. King, Ph.D.
Demographic and Behavioral Sciences Branch (DBS)
Eunice
Kennedy Shriver National Institute of Child Health and Human
Development (NICHD)
6100 Executive Blvd., Room 8B07, MSC 7510
Bethesda, MD 20892-7510
Rockville, MD 20852 (for express/courier service;
non-USPS service)
Telephone: 301-435-6986
Email: rozking@mail.nih.gov
The forms package associated with this FOA includes all applicable components, mandatory and optional. Please note that some components marked optional in the application package are required for submission of applications for this FOA. Follow all instructions in the SF424 (R&R) Application Guide to ensure you complete all appropriate optional components.
All page limitations described in the SF424 Application Guide and the Table of Page Limits must be followed.
All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:
Resource Sharing Plan
Individuals are required to comply with the instructions for the Resource Sharing Plans (Data Sharing Plan, Sharing Model Organisms, and Genome Wide Association Studies; GWAS) as provided in the SF424 (R&R) Application Guide.
Appendix
Do not use the appendix to circumvent page limits. Follow all instructions for the Appendix as described in the SF424 (R&R) Application Guide.
Foreign (non-US) institutions must follow policies described in the NIH Grants Policy Statement, and procedures for foreign institutions described throughout the SF424 (R&R) Application Guide.
Part I. Overview Information contains information about Key Dates. Applicants are encouraged to submit in advance of the deadline to ensure they have time to make any application corrections that might be necessary for successful submission.
Organizations must submit applications via Grants.gov, the online portal to find and apply for grants across all Federal agencies. Applicants must then complete the submission process by tracking the status of the application in the eRA Commons, NIH’s electronic system for grants administration.
Applicants are responsible for viewing their application in the eRA Commons to ensure accurate and successful submission.
Information on the submission process and a definition of on-time submission are provided in the SF424 (R&R) Application Guide.
This initiative is not subject to intergovernmental review.
All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.
Pre-award costs are allowable only as described in the NIH Grants Policy Statement.
Applications must be submitted electronically following the instructions described in the SF 424 (R&R) Application Guide. Paper applications will not be accepted.
Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.
For assistance with your electronic application or for more information on the electronic submission process, visit Applying Electronically.
Important
reminders:
All PD/PIs must include their eRA Commons ID in the Credential
field of the Senior/Key Person Profile Component of the SF 424(R&R) Application
Package. Failure to register in the Commons and to include a valid PD/PI
Commons ID in the credential field will prevent the successful submission of an
electronic application to NIH.
The applicant organization must ensure that the DUNS number it provides on the
application is the same number used in the organization’s profile in the eRA
Commons and for the Central Contractor Registration (CCR). Additional
information may be found in the SF424 (R&R) Application Guide.
See more
tips for avoiding common errors.
Upon receipt, applications will be evaluated for completeness by the Center for Scientific Review and responsiveness by components of participating organizations, NIH. Applications that are incomplete and/or nonresponsive will not be reviewed.
Applicants are required to follow the instructions for post-submission materials, as described in NOT-OD-10-115.
Only the review criteria described below will be considered in the review process. As part of the NIH mission, all applications submitted to the NIH in support of biomedical and behavioral research are evaluated for scientific and technical merit through the NIH peer review system.
For this particular announcement, note the following: OppNet uses the NIH definition of basic behavioral and social science research (b-BSSR, http://obssr.od.nih.gov/about_obssr/BSSR_CC/BSSR_definition/definition.aspx).
The R21 exploratory/developmental grant supports investigation of novel scientific ideas or new model systems, tools, or technologies that have the potential for significant impact on biomedical or biobehavioral research. An R21 grant application need not have extensive background material or preliminary information. Accordingly, reviewers will focus their evaluation on the conceptual framework, the level of innovation, and the potential to significantly advance our knowledge or understanding. Appropriate justification for the proposed work can be provided through literature citations, data from other sources, or, when available, from investigator-generated data. Preliminary data are not required for R21 applications; however, they may be included if available.
Reviewers will provide an overall impact/priority score to reflect their assessment of the likelihood for the project to exert a sustained, powerful influence on the research field(s) involved, in consideration of the following review criteria and additional review criteria (as applicable for the project proposed).
Reviewers will consider each of the review criteria below in the determination of scientific merit, and give a separate score for each. An application does not need to be strong in all categories to be judged likely to have major scientific impact. For example, a project that by its nature is not innovative may be essential to advance a field.
Significance
Does the project address an important problem or a critical barrier to progress in the field? If the aims of the project are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? How will successful completion of the aims change the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field? Does the project identify a significant opportunity to advance knowledge about the nature of behavior and/or social systems and/or deepen our understanding of basic mechanisms of behavioral and social processes? Does the project have the potential to inform biological or translational sciences relevant to the Nation’s health and well-being? If animal studies are proposed, does the application articulate relevance to individual or social human behavior?
Investigator(s)
Are the PD/PIs, collaborators, and other researchers well suited to the project? If Early Stage Investigators or New Investigators, or in the early stages of independent careers, do they have appropriate experience and training? If established, have they demonstrated an ongoing record of accomplishments that have advanced their field(s)? If the project is collaborative or multi-PD/PI, do the investigators have complementary and integrated expertise; are their leadership approach, governance and organizational structure appropriate for the project?
Innovation
Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? Are the concepts, approaches or methodologies, instrumentation, or interventions novel to one field of research or novel in a broad sense? Is a refinement, improvement, or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions proposed? Does this project have the potential to discover novel basic biopsychosocial paradigms to account for potential interactions between sleep-wake and circadian regulation and function and the social environment?
Approach
Are the overall strategy, methodology, and analyses
well-reasoned and appropriate to accomplish the specific aims of the project?
Are potential problems, alternative strategies, and benchmarks for success
presented? If the project is in the early stages of development, will the
strategy establish feasibility and will particularly risky aspects be
managed?
If the project involves clinical research, are the plans for 1) protection of
human subjects from research risks, and 2) inclusion of minorities and members
of both sexes/genders, as well as the inclusion of children, justified in terms
of the scientific goals and research strategy proposed?
Environment
Will the scientific environment in which the work will be done contribute to the probability of success? Are the institutional support, equipment and other physical resources available to the investigators adequate for the project proposed? Will the project benefit from unique features of the scientific environment, subject populations, or collaborative arrangements?
As applicable for the project proposed, reviewers will evaluate the following additional items while determining scientific and technical merit, and in providing an overall impact/priority score, but will not give separate scores for these items.
Protections for Human Subjects
For research that involves human subjects but does
not involve one of the six categories of research that are exempt under 45 CFR
Part 46, the committee will evaluate the justification for involvement of human
subjects and the proposed protections from research risk relating to their
participation according to the following five review criteria: 1) risk to
subjects, 2) adequacy of protection against risks, 3) potential benefits to the
subjects and others, 4) importance of the knowledge to be gained, and 5) data
and safety monitoring for clinical trials.
For research that involves human subjects and meets the criteria for one or
more of the six categories of research that are exempt under 45 CFR Part 46,
the committee will evaluate: 1) the justification for the exemption, 2) human
subjects involvement and characteristics, and 3) sources of materials. For
additional information on review of the Human Subjects section, please refer to
the Human
Subjects Protection and Inclusion Guidelines.
Inclusion of Women, Minorities, and Children
When the proposed project involves clinical research, the committee will evaluate the proposed plans for inclusion of minorities and members of both genders, as well as the inclusion of children. For additional information on review of the Inclusion section, please refer to the Human Subjects Protection and Inclusion Guidelines.
Vertebrate Animals
The committee will evaluate the involvement of live vertebrate animals as part of the scientific assessment according to the following five points: 1) proposed use of the animals, and species, strains, ages, sex, and numbers to be used; 2) justifications for the use of animals and for the appropriateness of the species and numbers proposed; 3) adequacy of veterinary care; 4) procedures for limiting discomfort, distress, pain and injury to that which is unavoidable in the conduct of scientifically sound research including the use of analgesic, anesthetic, and tranquilizing drugs and/or comfortable restraining devices; and 5) methods of euthanasia and reason for selection if not consistent with the AVMA Guidelines on Euthanasia. For additional information on review of the Vertebrate Animals section, please refer to the Worksheet for Review of the Vertebrate Animal Section.
Biohazards
Reviewers will assess whether materials or procedures proposed are potentially hazardous to research personnel and/or the environment, and if needed, determine whether adequate protection is proposed.
Resubmissions
For Resubmissions, the committee will evaluate the application as now presented, taking into consideration the responses to comments from the previous scientific review group and changes made to the project.
Renewals
Not Applicable
Revisions
Not Applicable
As applicable for the project proposed, reviewers will consider each of the following items, but will not give scores for these items, and should not consider them in providing an overall impact/priority score.
Applications from Foreign Organizations
Reviewers will assess whether the project presents special opportunities for furthering research programs through the use of unusual talent, resources, populations, or environmental conditions that exist in other countries and either are not readily available in the United States or augment existing U.S. resources.
Select Agent Research
Reviewers will assess the information provided in this section of the application, including 1) the Select Agent(s) to be used in the proposed research, 2) the registration status of all entities where Select Agent(s) will be used, 3) the procedures that will be used to monitor possession use and transfer of Select Agent(s), and 4) plans for appropriate biosafety, biocontainment, and security of the Select Agent(s).
Resource Sharing Plans
Reviewers will comment on whether the following Resource Sharing Plans, or the rationale for not sharing the following types of resources, are reasonable: 1) Data Sharing Plan; 2) Sharing Model Organisms; and 3) Genome Wide Association Studies (GWAS).
Budget and Period of Support
Reviewers will consider whether the budget and the requested period of support are fully justified and reasonable in relation to the proposed research.
Applications will be evaluated for scientific and technical
merit by (an) appropriate Scientific Review Group(s), convened by the Center for Scientific Review (CSR) , in accordance with NIH peer
review policy and procedures, using the stated review
criteria. Review assignments will be shown in the eRA Commons.
As part of the scientific peer review, all applications:
Applications will be assigned to the appropriate NIH Institute or Center. Applications will compete for available funds with all other recommended applications submitted in response to this FOA. Following initial peer review, recommended applications will receive a second level of review by the appropriate national Advisory Council or Board. The following will be considered in making funding decisions:
After the peer review of the application is completed, the PD/PI will be able to access his or her Summary Statement (written critique) via the eRA Commons.
Information regarding the disposition of applications is available in the NIH Grants Policy Statement.
If the application is under consideration for funding, NIH
will request "just-in-time" information from the applicant as
described in the NIH Grants
Policy Statement.
A formal notification in the form of a Notice of Award (NoA) will be provided
to the applicant organization for successful applications. The NoA signed by
the grants management officer is the authorizing document and will be sent via
email to the grantee’s business official.
Awardees must comply with any funding restrictions described in Section IV.5. Funding Restrictions. Selection
of an application for award is not an authorization to begin performance. Any
costs incurred before receipt of the NoA are at the recipient's risk. These
costs may be reimbursed only to the extent considered allowable pre-award costs.
Any application awarded in response to this FOA will be subject to the DUNS,
CCR Registration, and Transparency Act requirements as noted on the Award
Conditions and Information for NIH Grants website.
All NIH grant and cooperative agreement awards include the NIH Grants Policy Statement as part of the NoA. For these terms of award, see the NIH Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards, Subpart A: General and Part II: Terms and Conditions of NIH Grant Awards, Subpart B: Terms and Conditions for Specific Types of Grants, Grantees, and Activities. More information is provided at Award Conditions and Information for NIH Grants.
Cooperative Agreement Terms and Conditions of Award
Not Applicable
When multiple years are involved, awardees will be required to submit the Non-Competing Continuation Grant Progress Report (PHS 2590) annually and financial statements as required in the NIH Grants Policy Statement.
A final progress report, invention statement, and the expenditure data portion of the Federal Financial Report are required for closeout of an award, as described in the NIH Grants Policy Statement.
The Federal Funding Accountability and Transparency Act of 2006 (Transparency Act), includes a requirement for awardees of Federal grants to report information about first-tier subawards and executive compensation under Federal assistance awards issued in FY2011 or later. All awardees of applicable NIH grants and cooperative agreements are required to report to the Federal Subaward Reporting System (FSRS) available at www.fsrs.gov on all subawards over $25,000. See the NIH Grants Policy Statement for additional information on this reporting requirement.
We encourage inquiries concerning this funding opportunity and welcome the opportunity to answer questions from potential applicants.
Grants.gov
Customer Support (Questions regarding Grants.gov registration and
submission, downloading or navigating forms)
Contact Center Phone: 800-518-4726
Email: support@grants.gov
GrantsInfo (Questions regarding application instructions and
process, finding NIH grant resources)
Telephone 301-710-0267
TTY 301-451-5936
Email: GrantsInfo@nih.gov
eRA Commons Help Desk(Questions regarding eRA Commons
registration, tracking application status, post submission issues)
Phone: 301-402-7469 or 866-504-9552 (Toll Free)
TTY: 301-451-5939
Email: commons@od.nih.gov
Rosalind B. King, Ph.D.
Demographic and Behavioral Sciences Branch (DBS)
Eunice
Kennedy Shriver National Institute of Child Health and Human
Development (NICHD)
6100 Executive Blvd., Room 8B07, MSC 7510
Bethesda, MD 20892-7510
Rockville, MD 20852 (for express/courier service; non-USPS
service)
Telephone: (301) 435-6986
Fax: (301) 496-0962
Email: rozking@mail.nih.gov
Daniel S. Lewin, Ph.D., D.ABSM
National Center on Sleep Disorders Research
National Heart Lung and Blood Institute (NHLBI)
Two Rockledge Centre, Room 10183
6701 Rockledge Drive
Bethesda, MD 20892-7952
Telephone: (301) 443-4027
Fax: (301) 480-3451
Email: LewinDS@nhlbi.nih.gov
Examine your eRA Commons account for review assignment and contact information (information appears two weeks after the submission due date).
Bryan S. Clark, M.B.A.
Chief Grants Management Officer
Eunice
Kennedy Shriver National Institute of Child Health and Human
Development (NICHD)
6100 Executive Boulevard, Room 8A01, MSC 7510
Bethesda, MD 20892
Rockville, MD 20852 (for express/courier service; non-USPS
service)
Telephone: (301) 435-6975
FAX: (301) 402-0915
Email: clarkb1@mail.nih.gov
Recently issued trans-NIH policy notices may affect your application submission. A full list of policy notices published by NIH is provided in the NIH Guide for Grants and Contracts. All awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.
Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 45 CFR Parts 74 and 92.
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