THE NCI SCHOLARS PROGRAM

Release Date:  March 9, 2000

RFA:  CA-01-007

National Cancer Institute

Letter of Intent Receipt Date: May 8, 2000
Application Receipt Date: June 12, 2000

This Request for Applications (RFA) is a reissue of RFA CA-98-026 "The NCI 
Scholars Program" which was released in the NIH Guide on November 25, 1998.

PURPOSE

The purpose of the NCI Scholars Program is to provide an opportunity for 
outstanding new investigators to begin their independent research careers 
first within the special environment on the intramural campuses of the 
National Cancer Institute (NCI) and second to continue their careers at an 
institution of their choice.  This program is designed to encourage 
exceptionally well qualified new investigators to establish themselves in the 
cancer research field by providing them with independent research funding.  
This is accomplished by providing through an NCI intramural funding mechanism 
for up to four years the necessary resources to initiate an independent 
research program at the NCI, followed by support for two years through an 
extramural funding mechanism (K22) of their research program at the extramural 
institution to which they are recruited.

HEALTHY PEOPLE 2010

The Public Health Service (PHS) is committed to achieving the health promotion 
and disease prevention objectives of "Healthy People 2010," a PHS-led national 
activity for setting priority areas. This RFA, The NCI Scholars Program, is 
related to the priority area of human resource development.  Potential 
applicants may obtain a copy of "Healthy People 2010" at 
http://www.health.gov/healthypeople/.

ELIGIBILITY REQUIREMENTS

Individuals with a research or health professional doctoral level degree or 
equivalent, who are recognized by their peers and mentors as exceptional but 
with no more than five years of postdoctoral research training at the time of 
application, are eligible to apply.  These individuals should possess 
outstanding abilities in basic biomedical, clinical or population-based (e.g., 
epidemiological, behavioral, prevention or control) research, mathematics, or 
in technology-based research.  This includes individuals with research 
experience in any environment (e.g., academic, industry, government).  
Individuals who have had more than five years of postdoctoral research 
training at the time of application are NOT eligible to apply; however, 
clinical training does not count against the five years of research 
experience.  Individuals who have been principal investigators on either 
Public Health Service (PHS) research grants (e.g., R29, R01, P01 or  
subprojects) or non-PHS peer reviewed research grants are NOT eligible to 
apply for this award.  Postdoctoral fellows in intramural programs at the NCI 
who meet the Eligibility Requirements are eligible to apply, but will not be 
placed in Laboratories/Branches where they have previously trained.

Minorities and women and persons with disabilities are encouraged to apply.  
Candidates must be U.S. citizens or non-citizen nationals, or must have been 
lawfully admitted for permanent residence and possess an Alien Registration 
Card (I-151 or I-152) or some other verification of legal admission as a 
permanent U.S. resident, at the time of the award.  Non-citizen nationals, 
although not U.S. citizens, owe permanent allegiance to the U.S.  They are 
usually born in lands that are not states, but are under U.S. sovereignty, 
jurisdiction, or administration.  Individuals on temporary or student visas 
are NOT eligible to apply.

All applicants are encouraged to contact the NCI regarding their eligibility 
for this award (see Inquiries Section).

MECHANISM OF SUPPORT

The NCI Scholars Program consists of an Intramural Phase and an Extramural 
Phase.  The program begins with up to four years of support for the Scholar's 
independent research initiative in the NCI's intramural research program.  
Salary and research costs for this phase will be derived exclusively from 
intramural NCI resources.  There is no grant award associated with this phase. 
The final two years of the Scholar's research program are supported by the 
extramural institution to which the scholar is recruited and will be funded 
through an extramural, NIH Career Transition Award (K22) mechanism.   
Responsibility for the planning, direction, and execution of the proposed 
project will be solely that of the applicant.  

FUNDS AVAILABLE

It is anticipated that applications for the NCI Scholar's Program will be 
solicited annually.  Each annual solicitation will indicate the general areas 
of research and the number of positions that will be sponsored.  For the 
Intramural Phase, approximately $1,500,000 per year for up to four years will 
be set aside to fund about 10 awards.  However, this funding level is 
dependent upon the receipt of a sufficient number of meritorious applications 
as evaluated by peer review (see section on REVIEW CONSIDERATIONS).  The 
number of Scholars who can be supported is based upon the availability of 
resources and space in each sponsoring intramural Division.

For the Extramural Phase, approximately $1,250,000 per year in direct costs 
will be available to fund about 10 awards, providing support for salaries and 
partial operating costs.  It is important to note that a sponsoring extramural 
institution may submit an application only after the Scholar has been notified 
in writing that the NCI Progress Review Committee has recommended approval of 
the transition to the Extramural Phase of the award.  The individuals noted in 
the section on INQUIRIES should be consulted for any clarifications of intent 
or content.

Although this program is provided for in the financial plans of the NCI, the 
support of research programs pursuant to this RFA is also contingent upon the 
availability of funds for this purpose.

RESEARCH OBJECTIVES

Background

For decades, the intramural research program of the National Cancer Institute 
has provided an extraordinary research environment for the training of new 
scientists who go on to become leaders in the extramural biomedical research 
community. In addition to enriching the NCI intramural research environment 
with new investigators, the Scholar’s Program is uniquely designed to 
facilitate the transition of the NCI Scholars to independent research careers 
in the extramural community.

Goals and Scope

The NCI Scholar's Program is designed to enable exceptional junior 
investigators in basic, clinical or population-based biomedical research to 
establish their first independent research program.  This would include 
individuals with backgrounds in specialized fields such as mathematics, 
technology development, etc., who wish to initiate cancer research programs.  
The Program offers a novel opportunity for new investigators who are 
exceptionally talented to establish an independent research program early in 
their careers.  NCI Scholars will independently design and pursue their 
research projects with facilities, and operating budget for salary and 
personnel provided by NCI.  NCI Scholars will be responsible for all aspects 
of their research program, including the progress of the research and the 
management of allocated resources.  While the Scholars will not have a formal 
research mentor, they will receive orientation and guidance into the NCI/NIH 
environment and other support necessary to carry out their research.

The NCI intramural divisions invite applications for the NCI Scholars Program 
in the following scientific areas:

o  The Division of Basic Sciences encourages applications from candidates with 
an exceptional ability to identify key research problems and strong evidence 
of the ability to develop and run an independent, focused, hypothesis-driven 
research program.  Applications are invited in the general research areas of 
cell biology, cancer genetics and immunology.  For example, proposals could 
address problems relating to cellular transformation, oncogenes, tumor 
suppressor genes, apoptosis, signal transduction, regulation, chromatin 
structure, structural biology, cellular carcinogenesis, tumor biology, viral 
immunology, tumor immunology, developmental biology, and cell cycle 
regulation.

o  The Division of Cancer Epidemiology and Genetics encourages applications 
from candidates with experience and interest in pursuing epidemiologic or 
interdisciplinary research into environmental and genetic determinants of 
cancer in a highly integrative and collaborative research environment.   Areas 
of special research interest include: lifestyle factors such as diet and 
nutrition; genetic and familial susceptibility; occupational exposures and 
environmental pollution; infectious agents; radiation exposures; 
pharmacoepidemiology; and methodologic research in biostatistics and 
bioinformatics, exposure assessment, and genetic and molecular epidemiology.

o The Division of Clinical Sciences encourages applications from candidates 
with an interest in research that links the concepts of the clinic with the 
concepts of the   laboratory.  Candidates are expected to develop an 
independent and focused research program that will likely include 
collaborations with clinicians and basic scientists.  Areas of research 
interest include angiogenesis, apoptosis, cancer biology, gene expression, 
gene therapy, developmental therapeutics and immunotherapy.  The diseases 
studied include AIDS and AIDS related malignancies, breast cancer, childhood 
tumors, colorectal cancer, kidney cancer, lung cancer, lymphoma, melanoma, 
ovarian cancer, and prostrate cancer.  Applications are encouraged from 
candidates with research experience in basic science and/or clinical science 
who want to develop their research programs in an exceptional environment 
where research findings impact directly on clinical practice.  Individuals 
with training in mathematics or engineering are encouraged to propose programs 
where their unique backgrounds can interface with ongoing development of novel 
technologies.

Allowable Costs

Intramural  Phase: The budget for the intramural support phase will be 
approximately  $200,000 per year in total costs excluding equipment. The final 
budget for this phase of the award will be negotiated with the sponsoring NCI 
intramural division and will depend upon the nature and scope of the research 
as recommended by the peer review process. 

Salaries will be provided for the Scholar and up to two additional support 
positions (e.g., a Cancer Research Training Award (CRTA) fellow and a Cancer 
Research Training Award (CRTA) technical fellow.)  The salary range for the 
Intramural Phase of the Scholar’s award is $46,000 to $60,000 per annum.   The 
salary will be based upon the Scholar’s level of training and experience and 
will be determined through negotiation with the sponsor.  Stipends for CRTA 
fellows and technical fellows are based on their highest degree(s) attained 
and years of experience and are posted in the CRTA guidelines. 
 
Up to $22,500 per person per year will be provided for research supplies and 
services, including chemicals, biologicals, etc.  A Scholar with two CRTA 
fellows would have a supplies and services budget up to $67,500.

Additional budget expenses, such as animal costs and required equipment, will 
be provided as necessary and negotiated with the NCI. Equipment purchased for 
the Scholar during the Intramural Phase will not be transferable to the 
extramural position. 

Extramural Phase: The budget for the two-year extramural transition phase may 
not exceed $125,000 plus fringe benefits per year in direct costs.

At the extramural institution, Scholars will be provided salary support of up 
to $75,000 plus applicable fringe benefits commensurate with the applicant 
institution's salary structure for persons of equivalent qualifications, 
experience and rank.  The total salary requested must be based on a full-time, 
12-month staff appointment and there should be no less than 75 percent effort 
devoted by the Scholar specifically to the proposed research program.  The 
institution may supplement the NCI contribution. However, supplementation may 
not be from Federal funds unless specifically authorized by the Federal 
program from which such funds are derived.  In no case may PHS funds be used 
for salary supplementation.  Institutional supplementation of salary may not 
require extra duties or responsibilities that would interfere with the purpose 
of this award. This grant is included under Expanded Authorities.  However, 
funds available for the salary of the principal investigator will be 
restricted and may not be rebudgeted without the approval of the NCI.

Up to $50,000 per year in direct costs will be provided to partially support 
ancillary personnel, supplies, equipment, travel, tuition, and other costs 
which are deemed essential for the individual's research program.

Facilities and administrative (F&A) costs are now reimbursed at 8% modified 
total costs.

During the Extramural Phase, the Scholar is encouraged to apply for additional 
support through investigator-initiated research grants, e.g., R01, R03, R21.  
The K22 and an R series grant may be held concurrently, but salary can only be 
provided through the K22 (and supplements as noted above) during the overlap 
years.

Special Restrictions

Acceptance into the NCI Scholar's Program does not convey any commitment or 
intent of the NCI to consider the Scholar for a tenure track position within 
the NCI.  The NCI Scholars Program is specifically intended to help develop 
scientists who will pursue their careers in the extramural biomedical research 
community. However, NCI Scholars are not explicitly precluded from applying 
for available tenure track positions at the NIH.  If a Scholar obtains an NIH 
position, the NCI Scholar's Career Transition Award (K22) will be terminated.

INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS

It is the policy of the NIH that women and members of minority groups and 
their subpopulations must be included in all NIH supported biomedical and 
behavioral research projects involving human subjects, unless a clear and 
compelling rationale and justification is provided that inclusion is 
inappropriate with respect to the health of the subjects or the purpose of the 
research.  This policy results from the NIH Revitalization Act of 1993.

All investigators proposing research involving human subjects should read the 
NIH Guidelines For Inclusion of Women and Minorities as Subjects in Clinical 
Research which were published in the Federal Register of March 28, 1994 (FR 59 
14508-14513), and in the NIH Guide for Grants and Contracts, Volume 23, Number 
11, March 18, 1994, available on the web at the following URL address: 
http://grants.nih.gov/grants/guide/notice-files/not94-100.html

Investigators may obtain copies from these sources or from the program staff 
or contact person listed under INQUIRIES.  Program staff may also provide 
additional relevant information concerning the policy.

NIH POLICY AND GUIDELINES ON THE INCLUSION OF CHILDREN AS PARTICIPANTS IN 
RESEARCH INVOLVING HUMAN SUBJECTS

It is the policy of NIH that children (i.e., individuals under the age of 21) 
must be included in all human subjects research, conducted or supported by 
NIH, unless there are scientific and ethical reasons not to include them. This 
policy applies to all applications submitted in response to this RFA.  All 
investigators proposing research involving human subjects should read the "NIH 
Policy And Guidelines on The Inclusion of Children as Participants in Research 
Involving Human Subjects" that was published in the NIH Guide For Grants And 
Contracts, March 6, 1998 and is available at the following URL address: 
http://grants.nih.gov/grants/guide/notice-files/not98-024.html

URLS IN NIH GRANT APPLICATIONS OR APPENDICES

All applications and proposals for NIH funding must be self-contained within 
specified page limitations. Unless otherwise specified in an NIH solicitation, 
internet addresses (URLs) should not be used to provide information necessary 
to the review because reviewers are under no obligation to view the Internet 
sites. Reviewers are cautioned that their anonymity may be compromised when 
they directly access an Internet site.

LETTER OF INTENT

Prospective applicants are asked to submit, by May 8, 2000, a letter of intent 
that includes a descriptive title of the proposed research, the name, address, 
telephone and FAX numbers, and email address of the Principal Investigator, 
and the number and title of the RFA in response to which the application may 
be submitted.  Although a letter of intent is not required, is not binding, 
and does not enter into the review of a subsequent application, it allows NCI 
staff to estimate the potential review workload and avoid conflict of interest 
in the review.

The letter of intent is to be sent to the program staff listed under INQUIRIES 
by the letter of intent receipt date listed in the heading of this RFA.

APPLICATION PROCEDURES

The research grant application form PHS 398 (rev. 4/98) is to be used in 
applying for these grants.  These forms are available at most institutional 
offices of sponsored research and may be obtained from the Division of 
Extramural Outreach and Information Resources, National Institutes of Health, 
6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910, telephone: 
301/435-0714, Email: grantsinfo@nih.gov.  For those applicants with internet 
access, the 398 kit may be found at http://grants.nih.gov/grants/forms.htm

The RFA label available in the PHS 398 (rev. 4/98) application form must be 
affixed to the bottom of the face page of the application.  Type the RFA 
number on the label.  Failure to use this label could result in delayed 
processing of the application such that it may not reach the review committee 
in time for review.  In addition, the RFA title and number must be typed on 
line 2 of the face page of the application form and the YES box must be 
marked.

The sample RFA label available at: 
http://grants.nih.gov/grants/funding/phs398/label-bk.pdf has been modified to 
allow for this change. Please note this is in pdf format.

Submit a signed, typewritten original of the application and three signed 
photocopies in one package to:

Center for Scientific Review 
National Institutes of Health
6701 Rockledge Drive, Room 1040 - MSC 7710
Bethesda, Md  20892-7710
Bethesda, Md  20817 (for express/courier service)

At the time of submission, two additional copies of the application must be 
sent to:

Ms. Toby Friedberg
Division of Extramural Activities
National Cancer Institute
6116 Executive Boulevard, Room 8062, MSC 8239
Bethesda, MD  20892-8239
Rockville, MD 20852 (for express/courier service)

Applications must be received by June 12, 2000.  If an application is received 
after that date, it will be returned to the applicant without review.  The 
Center for Scientific Review (CSR) will not accept any application in response 
to this RFA that is essentially the same as one currently pending initial 
review, unless the applicant withdraws the pending application.  The CSR will 
not accept any application that is essentially the same as one already 
reviewed.  This does not preclude the submission of substantial revisions of 
applications already reviewed, but such applications must include an 
introduction addressing the previous critique.

The initial application for the NCI Scholars Program will not be processed 
through your current institution; therefore, follow the supplemental 
guidelines below.

Supplemental Application Guidelines

The RFA title (NCI Scholar's Program) and the RFA number must be typed on line 
2 of the face page of the application, and the YES box must be marked.

The applicant must provide her/his signature in item 15; signature is not 
required for item 16.

Leave items 9-14 and 16 on the face page blank.

Enter in item 6 (Dates of Proposed Period of Support) the combined 6 years of 
support needed to complete the intramural and the extramural support phases of 
the NCI Scholars Program.

A Checklist Page is NOT to be submitted.

Applicants who are not U.S. citizens must provide an official certified 
transcript covering medical school or the graduate school level of education.

A total of three sealed letters of reference from well-established basic or 
clinical scientists must be provided.  One letter should be from the most 
recent mentor in either a postdoctoral research setting or from the 
applicant's thesis advisor.  These letters are to be attached to the face page 
of the original application.  The letters should address the following issues:

     --The applicant's past contributions to scientific achievements
     --The applicant's special potential to pursue and develop an independent 
research program
     --The applicant's ability to work with other scientists in various 
interactive situations, (e.g., seminars, journal clubs, etc.), on 
collaborative research projects, and with support staff  (e.g., technicians, 
secretaries).

Career Development Plan:

Applicants should describe their overall career goals and plans for continued 
scientific development in their research career, including the need for any 
courses, research techniques or methods, etc.

Research Plan:

The scientific objectives and specific aims should describe research plans 
that are sufficient to justify up to four years of support.  Applicants should 
also provide future research directions for the extramural support phase, 
i.e., what are the broad research goals and potential avenues of research that 
would be stimulated by your specific research project.

Budget:

Do NOT provide any dollar figures in the application.  The final budget will 
be negotiated when a selected applicant accepts a position and will be within 
the allowable costs specified above as well as consistent with the 
peer-reviewed recommended scope of the research program.

Using continuation pages as needed, provide in a detailed narrative format 
justification for the budgetary needs of the proposed research program, e.g. 
personnel, consultants,  equipment, animals, patient populations, databases, 
supplies and travel.  This justification  should be prepared carefully, since 
it will be a critical factor used by peer reviewers in evaluating the 
applicant's knowledge and ability to manage the proposed research project.

Extramural (Transition) Phase:

After the Scholar/Awardee receives approval in writing for the transition to 
extramural support  (See section on SELECTION PROCESS, Extramural Phase), the 
Scholar should contact NCI staff for change of institution procedures (see 
section on INQUIRIES).

REVIEW CONSIDERATIONS

Upon receipt, applications will be reviewed by the Center for Scientific 
Review (CSR) for completeness.  Incomplete applications will be returned to 
the applicant without further consideration.  Applications also will be 
evaluated for responsiveness to this RFA.  This will be done by program staff 
of the NCI, the main criteria being the applicant's eligibility and whether or 
not the research proposal is reasonably within the scientific areas of 
interest declared by the participating intramural divisions of the NCI (see 
section on RESEARCH OBJECTIVES, Goals and Scope).  Applications that are not 
responsive to the objectives of the RFA will be returned to the applicant 
without review.

Applications that are complete and responsive to this RFA will be evaluated 
for scientific and technical merit in accordance with the review criteria 
stated below by an appropriate extramural initial peer review group (IRG) 
convened by the NCI Division of Extramural Activities. As part of the initial 
merit review, all applications will receive a written critique and may undergo 
a process in which only those applications deemed to have the highest 
scientific merit, generally the top half of the applications under review, 
will be discussed and assigned a priority score and receive a second level of 
review by the National Cancer Advisory Board.

Review Criteria:

The peer review criteria for applications submitted in response to this RFA 
are:

Candidate

o Capacity to carry out independent research based on level of training, 
experience and competence commensurate with the purposes of this award.

o Past and present research productivity, e.g., contributions to the 
scientific literature; success in obtaining fellowships.  The level of 
achievement will be judged relative to the number of years of training.


o Ability to conceptualize and organize a research approach that will make 
full use of the six years of support offered under this program.

o The special qualities of the applicant to work in a scientifically 
interactive setting and  collaborate with other scientists.  This should be 
addressed in the letters of reference (see section on APPLICATION PROCEDURES).

o Appropriateness of the applicant's Career Development Plan and the 
likelihood that the award will contribute substantially to the continued 
scientific development and productivity of the candidate.

o Potential to become an outstanding scientist who will make significant 
contributions to the field.

Research Plan

o Quality and innovativeness of the research plan, including appropriateness 
and adequacy of the experimental approach and methodology proposed to carry 
out the research.

o Potential of the research plan for contributing to the scientific 
literature.

o Suitability of the proposed specific aims for the initial three to four year 
research program.

o Appropriateness of proposed future directions and broad research goals.

o Consistency of the research plan with the candidate's career goals.

o Where appropriate, adequacy of plans to include both genders and minorities 
and their subgroups for the scientific goals of the research.  Plans for 
recruitment and retention of subjects will also be evaluated.

Budget

o Justification of budget requests in relation to career development goals, 
research aims and  plans.

The initial review group will also examine: the appropriateness of proposed 
project budget and duration; the adequacy of plans to include both genders and 
minorities in their subgroups as appropriate for the scientific goals of the 
research and plans for the recruitment and retention of subjects; the adequacy 
of plans for including children as appropriate for the scientific goals of the 
research, or justification for exclusion; the provisions for the protection of 
human and animal subjects; and the safety of the research environment.

Selection Process

The priority score assigned to the application and the critique of the IRG 
will be mailed to the applicant.

Intramural Phase

A Scholars Selection Committee (SSC) consisting of extramural scientists, 
senior NCI scientists, and the Chief of the NCI Cancer Training Branch will 
identify the highly meritorious candidates to be invited to the NCI for 
interviews/ seminars.  Criteria for this selection will include the priority 
score and recommendations of the initial peer review committee, and 
programmatic priorities.  The recommendations of the SSC for each candidate 
will be reviewed for approval by the NCI Executive Committee. A ranking and 
matching process by both interviewees and the sponsoring intramural divisions 
will then be used to determine final intramural unit assignments.  Candidates 
who are successfully matched with a host intramural unit as a result of the 
recruitment process will be offered Scholars Awards.  The Cancer Training 
Branch will coordinate the notification of the candidates about the status of 
their application.

The specific terms of the intramural phase will be finalized in a “Scholars 
Agreement.” The applicant indicates his/her acceptance of the Scholars Award 
and the specific intramural appointment terms by signing the Scholar’s 
Agreement.  

Extramural Phase

Eligibility for the Extramural Phase funding of the Career Transition Award 
(K22) will be determined by a formal scientific progress review conducted by 
an NCI Progress Review Committee.  This review can be conducted at any time 
prior to the end of the third year of intramural support.  The results of the 
review will be presented in writing to the Scholar.  Approval will result in 
eligibility for the Extramural Phase funding of the Career Transition Award 
(K22) and up to one additional year of intramural support to facilitate the 
transition to an extramural laboratory.  Disapproval will result in a terminal 
fourth year of intramural support with no transition funding.  Regardless of 
when the approval for transition is obtained, the maximum duration of the 
Extramural Phase would remain at two years.

Prior to activation of the Extramural Phase of the program, the Scholar must 
obtain a position as an independent researcher at an eligible sponsoring 
extramural institution.  Application procedures for the non-competing NIH 
Career Transition Award (K22) will be provided by the NCI Grants 
Administration Branch (see section on INQUIRIES).

AWARD CRITERIA

Applications will compete for available positions/funds with all other scored 
applications submitted in response to this RFA.  The following will be 
considered in making award decisions:  Qualifications and potential of the 
applicant and quality of the proposed research project as determined by peer 
review; programmatic priorities; and availability of funds. 

EVALUATION

Intramural Phase

Each Scholar's research program will be evaluated for progress on an annual 
basis like all other independent intramural scientific research programs.  For 
this purpose, the Scholar will prepare on an annual basis a progress report, 
which will be evaluated by the corresponding laboratory/ branch chief and the 
appropriate NCI division director.  Additionally, the NCI will conduct a 
formal scientific progress review (See section on SELECTION PROCESS, 
Extramural Support Phase) no later than the end of the third year.

Extramural (Transition) Phase

The awardee will follow the same procedure as all other extramural grantees by 
submitting a progress report as part of the non-competing continuation 
application.  A description of the research and career progress will be 
provided including publications, current research grant support, and pending 
applications.  These annual reports will be closely monitored by NCI staff to 
ensure that the awardee is achieving the goals of the NCI Scholars Program. 
The NCI may solicit information from the awardee after completion of the 
Extramural Phase regarding their career progress, for the purpose of 
evaluating outcomes of the NCI Scholars Program.

SCHEDULE: Letter of Intent Receipt:         May 8, 2000.
          Application Receipt:              June 12, 2000.
          Review by NCAB:                   February, 2001.
          Earliest Anticipated Start Date:  April 1, 2001.		

INQUIRIES

Inquiries concerning this RFA are encouraged, especially during the planning 
phase of the application to clarify any issues or questions from potential 
applicants. NCI contacts for specific areas of expertise are listed below:

Direct inquiries regarding eligibility and other programmatic issues to:

Lester S. Gorelic, Ph.D.
Office of the Deputy Director for Extramural Sciences
National Cancer Institute
Executive Plaza North, Room 520
Bethesda, MD  20892-7390
Telephone: (301) 496-8580
Fax:  (301) 402-4472
Email: LG2H@NCI.GOV

Direct inquiries regarding the following to:

1.  Fiscal/administrative matters; and 2. At least two months prior to the 
transition from the Intramural Phase to the Extramural Phase, for information 
on procedures for submitting a non-competing application from the new 
applicant organization, using the PHS Form 398 and specifying change of 
grantee institution:

Ms. Catherine Blount
Grants Administration Branch
National Cancer Institute
Executive Plaza South, Room 243
Bethesda, MD  20892
Telephone:  (301) 496-3179
Fax:  (301) 496-8601
Email:  CB136G@NIH.GOV

Direct inquiries regarding review issues to:

Ms. Toby Friedberg 
Referral Officer 
Division of Extramural Activities 
National Cancer Institute 
6116 Executive Blvd., Room 8062, MSC-8239 
Rockville, MD 20852 (express courier)
Bethesda, MD 20892-8239
Telephone: (301) 496-3428
Fax: (301) 402-0275
Email: tf12w@nih.gov

AUTHORITY AND REGULATIONS

This program is described in the Catalog of Federal Domestic Assistance Number 
93.398, Cancer Research Manpower.  Awards are made under the authorization of 
 Sections 301 and 405 of the Public Health Service Act  as amended (42 USC 241 
and 284) and administered under NIH grants policies and Federal Regulations 42 
CFR Part 52 and 45 CFR Parts 74 and 92. This program is not subject to the 
intergovernmental review requirements of Executive Order 12372 or Health 
Systems Agency review.

The Public Health Service strongly encourages all grant recipients to provide 
a smoke-free workplace and promote the non-use of tobacco products. In 
addition, Public Law 103-227, The Pro-Children Act of 1994, prohibits smoking 
in certain facilities (or, in some cases, any portion of a facility) in which 
regular or routine education, library, day care, health care or early 
childhood development services are provided for children.  This is consistent 
with the PHS mission to protect  and advance the physical and mental health of 
the American people.

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