CANCER PREVENTION, CONTROL AND POPULATION SCIENCES CAREER DEVELOPMENT AWARD

Release Date:  June 3, 1999

PA NUMBER:  PAR-99-108

National Cancer Institute

PURPOSE

The purpose of the Cancer Prevention, Control and Population Sciences Career
Development Award (K07) is to support the career development of investigators
who have made a commitment to focus their research endeavors on cancer
prevention, control and the population sciences.  This mechanism provides
support for three to five years of specialized didactic study and mentored
research for individuals with a health professional or science doctoral degree
who are not fully established investigators and who want to pursue research
careers in the cancer prevention, control, population and/or behavioral
sciences.  Examples of relevant disciplines for this Program Announcement (PA)
include any aspect of human cancer prevention (modifiable risk factors, new
animal models and extrapolation of these models to human cancer, genetic
predisposition to cancer and detection of precursor lesions, chemoprevention
trials in human populations, and behavioral research and behavioral
intervention trials in cancer prevention), epidemiology (biochemical, genetic,
molecular), biostatistics, human cancer genetics, clinical oncology, human
nutrition, behavioral and social sciences, health promotion, health services
and health policy research; and medical decision analysis, survivorship and
quality of life as they relate to cancer.

For the purpose of this PA, cancer control research is defined as "basic and
applied research in the behavioral sciences that independently or in
combination with biomedical approaches, reduces cancer risk, incidence,
morbidity, and mortality across the lifespan and over the entire process of
carcinogenesis from primary behavioral prevention in youth, to screening,
treatment, and survivorship" (Report of the NCI Cancer Control Progress Review
Group, 1998).

This Program Announcement (PA) replaces the announcement titled, "Preventive
Oncology Academic Award (POAA)" which was published in the NIH GUIDE, Vol. 11,
No. 5, April 23, 1982.

This PA will expire in two years from the first receipt date.  NIH Grants
policies apply to these awards.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health promotion
and disease prevention objectives of "Healthy People 2000," a PHS-led national
activity for setting priority areas.  This PA, Cancer Prevention, Control and
Population Sciences Career Development Award, is related to the priority area
of human resource development.  Potential applicants may obtain a copy of
"Healthy People 2000" (Full Report:  Stock No. 017-001-00474-0 or Summary
Report:  Stock No. 017-001-00473-1) through the Superintendent of Documents,
Government Printing Office, Washington, DC 20402-9325 (telephone 202/512-
1800), or electronically http://www.crisny.org/health/us/health7.html.

ELIGIBILITY REQUIREMENTS

The candidate must have a Ph.D. degree, a health professional doctoral degree
(M.D., DPH., D.D.S., D.O., D.V.M., Pharm. D.) or equivalent, or be a
doctorally prepared oncology nurse; and must have a research or academic
appointment in the sponsoring institution at the time of award.  The candidate
must be able to spend a minimum of 75 percent full-time professional effort
conducting research and research career development during the period of the
award.

Applications may be submitted on behalf of candidates by domestic, non-Federal
organizations, public or private, such as medical, dental or nursing schools
or other institutions of higher education.  Racial/ethnic minority
individuals, women, and persons with disabilities are encouraged to apply as
principal investigators.  Candidates must be U.S. citizens or noncitizen
nationals, or must have been lawfully admitted for permanent residence and
possess an Alien Registration Receipt Card (I-151 or I-551) or some other
verification of legal admission as a permanent resident.  Noncitizen
nationals, although not U.S. citizens, owe permanent allegiance to the U.S. 
They are usually born in lands that are not states, but are under U.S.
sovereignty, jurisdiction, or administration.  Individuals on temporary or
student visas are not eligible.

Current and former principal investigators on NIH Small Grants (R03) or
Exploratory/Developmental Grants (R21) are eligible.  However, current and
former principal investigators on NIH research project (R01), FIRST Awards
(R29), sub-projects of program project (P01) or center grants (P50), or the
equivalent, are not eligible.  A candidate for the K07 may not simultaneously
submit or have pending an application for another career award (K01, K08,
K23), a research project grant (R01, R03), or any other PHS award that
duplicates the provisions of this award.  Awardees may submit an application
for an NCI Transition Career Development Award (K22), and are encouraged to
actively seek independent support of their research programs through
investigator-initiated grants during the term of this award.

MECHANISM OF SUPPORT

This PA will use the National Institutes of Health (NIH) K07 mechanism.
Planning, direction, and execution of the program will be the responsibility
of the candidate and her/his mentor on behalf of the applicant institution.
The total project period for an application submitted in response to this PA
may not exceed 5 years.  Awards made for a five year project period, or
recommended by peer review for a shorter project period, are not renewable.

RESEARCH OBJECTIVES

A.  Background: Recognizing a need for training researchers in preventive
oncology and the lack of  multidisciplinary curricula that would be needed for
this purpose, in 1982 the National Cancer Institute (NCI) published the
ANNOUNCEMENT titled "Preventive Oncology Academic Award" (NIH Guide for Grants
and Contracts, Vol. 11, No. 5, April 23, 1982).  This award (POAA) provided
support for the development of institutional preventive oncology curricula
focusing specifically on etiologic studies and primary prevention of cancer. 
The institution identified an outstanding faculty member with demonstrated
competence in preventive oncology to develop and coordinate the implementation
of the curricula.  In 1985 the NCI, made two significant changes in the award. 
First, the emphasis on support for institutional curriculum development was
changed to support of research and career development of individuals wanting
to make a transition to cancer prevention and control research, and to
individuals already trained in cancer prevention and control who are not yet
fully independent investigators.  Second, the original focus on cancer
etiology and primary cancer prevention was expanded to include all cancer
prevention and control sciences and technologies from hypothesis development
through demonstration.

The revised POAA has been highly successful in achieving its objectives.  Of
the 32 individuals having received a K07 award since 1986  and having
completed the full five year term of the award prior to 1998, 19 (59%) have
ongoing research programs in cancer prevention and control supported by
investigator-initiated grants, and 3 (8 %) have been principal investigators
on NCI Cancer Education (R25) grants focusing on cancer prevention and
control.  Additionally, a number of current and former K07 principal
investigators are nationally and internationally recognized leaders in the
field of cancer prevention and control.

In 1998, the National Cancer Institute completed major external reviews of its
programs in cancer prevention and control sciences.  The scientific experts
conducting these reviews identified the current level of support for training
in cancer prevention and cancer control and the single discipline emphasis of
these programs as being completely inadequate to take advantage of the new
opportunities for reducing cancer incidence, morbidity and mortality. These
experts recommended increasing the current level of NCI support of
education/training programs in cancer prevention and cancer control, and
generating new opportunities for multidisciplinary training in these
disciplines of basic and clinical scientists in highly interdisciplinary and
collaborative environments.  Similar recommendations regarding training
opportunities in cancer prevention and control have been made by other NCI
advisory groups.

B.  Program:  The award provides support for up to five consecutive 12-month
periods.  A minimum of 75 percent effort must be devoted to the program.  The
remaining 25 percent can be divided among other clinical and teaching
activities and coursework only if they are consistent with the program goals,
i.e. the candidate's development into an independent investigator.  Both the
didactic and the research phases of the award are expected to develop the
necessary knowledge and research skills in scientific areas relevant to the
career goals of the candidate in cancer prevention, cancer control, and
behavioral and population sciences research.  Candidates lacking skills in
data management, statistics, epidemiology, study design, clinical trial
design, hypothesis development, etc. can be provided the opportunity to
participate in courses designed to overcome these deficiencies.

C. Scope:  The Cancer Prevention, Control and Population Sciences Career
Development Award provides a career development opportunity for: 1)
individuals already proficient in general epidemiology, the behavioral
sciences, or other relevant disciplines; and, 2) individuals already trained
in cancer epidemiology, etiology, prevention, control and the behavioral and
population sciences to become fully independent investigators.  The scope of
the research/didactic training may extend from the development and
experimental testing of hypotheses, through the stage of confirming results
using defined populations, to the development and demonstration of technology
as applied to epidemiology, cancer prevention, cancer control; and the
behavioral and population sciences as they relate to cancer.

D.  Mentor(s):  The recipient must receive appropriate mentoring throughout
the duration of the program.  Where feasible, women, minority individuals and
individuals with disabilities should be involved as mentors and serve as role
models.  Candidates must name a primary mentor who, together with the
applicant, is responsible for the planning, direction, and execution of the
program.  The primary mentor should have sufficient independent research
support to provide for the research costs of the candidate's research program
in excess of the research support provided by this award.  Candidates may also
nominate co-mentors as appropriate to the goals of the program.

E.  Allowable Costs:

1.  Salary: The K07 award can provide salary up to $75,000 plus fringe
benefits.  The total salary requested must be based on a full-time, 12 month
appointment requiring the candidate to spend a minimum of 75 percent effort
conducting cancer research with the remaining effort being devoted to
activities related to the development of a successful research career.  The
salary must be consistent both with the established salary structure at the
institution and with salaries actually provided by the institution from its
own funds to other staff members of equivalent qualifications, rank, and
responsibilities in the department concerned.  If full-time, 12 month salaries
are not currently paid to comparable staff members, the salary proposed must
be appropriately related to the existing salary structure.

2.  Research Development Support:  Up to $30,000 per year can be provided for
the following types of expenses: (a) research expenses, such as supplies,
equipment, and technical personnel; (b) statistical services including
personnel and computer time; (c) tuition, fees, and books related to career
development; and (d) travel to research meetings or for training.

3.  Ancillary Personnel Support: Salary for mentors, secretarial and
administrative assistance, etc. is not allowed.

4. Facilities and Administrative Costs:  These costs, which were formerly
called indirect costs, will be reimbursed at 8 percent of modified total
direct costs.

F.  Evaluation:  In carrying out its stewardship of human resource-related
programs, the NIH may request information essential to an assessment of the
effectiveness of this program.  Accordingly, recipients are hereby notified
that they may be contacted after the completion of this award for periodic
updates on various aspects of their employment history, publications, support
from research grants or contracts, honors and awards, professional activities,
and other information helpful in evaluating the impact of the program.

G.  Other Income:  Fees resulting from clinical practice, professional
consultation, or other comparable activities required by the research and
research-related activities of this award may not be retained by the career
award recipient. Such fees must be assigned to the grantee institution for
disposition by any of the following methods:

The funds may be expended by the grantee institution in accordance with the
NIH policy on supplementation of career award salaries and to provide fringe
benefits in proportion to such supplementation.  Such salary supplementation
and fringe benefits payments must be within the established policies of the
grantee institution.

The funds may be used for health-related research purposes.

The funds may be paid to miscellaneous receipts of the U.S. Treasury.  Checks
should be made payable to the Department of Health and Human Services, NIH and
forwarded to the Director, Division of Financial Management, NIH, Bethesda,
Maryland 20892.  Checks must identify the relevant award account and reason
for the payment.

Awardees may retain royalties and fees for activities such as scholarly
writing, service on advisory groups, or honoraria from other institutions for
lectures or seminars, provided these activities remain incidental and provided
that the retention of such pay is consistent with the policies and practices
of the grantee institution.

Usually, funds budgeted in an NIH supported research or research training
grant for the salaries or fringe benefits of individuals, but freed as a
result of a career award, may not be rebudgeted.  The awarding component will
give consideration to approval for the use of released funds only under
unusual circumstances.  Any proposed retention of funds released as a result
of a career
award must receive prior written approval of the NIH awarding component.

H.  Special Leave:  Leave to another institution, including a foreign
laboratory, may be permitted if directly related to the purpose of the award.
Only local, institutional approval is required if such leave does not exceed 3
months.  For longer periods, prior written approval of the NCI is required. 
To obtain prior approval, the award recipient must submit a letter to the
Grants management Specialist listed on the Notice of Grant Award,
countersigned by his or her department head and the appropriate institutional
official, describing the reason for leave, the accommodations that will be
made at the new institution to ensure that the didactic training and research
objectives at the new institution remain within the scope of the award; and
providing assurance that the awardee's current position will be held for their
return.  THE AWARD RECIPIENT SHOULD CONTACT THE NCI PROGRAM DIRECTOR LISTED IN
INQUIRIES BEFORE SUBMITTING THE LETTER.

Leave without award support may not exceed 12 months. Such leave requires the
prior written approval of the NCI and will be granted only in unusual
situations.  Support from other sources is permissible during the period of
leave.  Such leave does not reduce the total number of months of program
support for which an individual is eligible.  Parental leave will be granted
consistent with the policies of the NIH and the grantee institution.

I.  Termination or Change of Institution:  When a grantee institution plans to
terminate an award, the NCI Grants Management Specialist listed on the Notice
of Grant Award must be notified in writing at the earliest possible time so
that appropriate instructions can be given for termination.  If the individual
is moving to another eligible institution, career award support may be
continued provided:

o  The awardee has submitted to the NCI a written request for a transfer,
countersigned by the appropriate institutional business official, describing
the reasons for the transfer and including the new sponsor's name and
biosketch.  The awardee must establish in this request that the specific aims
of the research program to be conducted at the new institution are within the
scope of the original peer reviewed research program, and a new sponsor has
been identified who has the appropriate research expertise and support to
provide adequate guidance to the awardee and research support for the
awardee's research program.  The awardee should contact the NCI Program
Director listed in INQUIRIES prior to submitting the request;

o  The NCI Program Director has recommended approval of the request and has
forwarded the request for further evaluation to the Grants Management
Specialist listed on the Notice of Grant Award;

o  A completed transfer application has been submitted to the Grants
Management Specialist listed in the Notice of Grant Award far enough in
advance of the requested effective date to allow the necessary time for
review, establishing that all conditions of the initial award will be met at
the new institution including the presence of a qualified mentor, and that the
period of support requested does not exceed the time remaining within the
existing award period.

J. Changes in Research Program:

Individual awards are made for career development at a specific institution in
a specific research program.  A change in the specified scientific area of the
research component of the career development program requires prior approval
of the NCI.

A scientific rationale must be provided for any proposed changes in the aims
of the original peer reviewed research plan.  The new research plan will be
evaluated by NCI staff to ensure that the plan remains within the scope of the
original peer reviewed research program.  If the new plan does not satisfy
this requirement, the award could be terminated.

In the event an award is terminated, the Director of the NIH shall notify the
grantee institution and career award recipient in writing of this
determination, the reasons therefore, the effective date, and the right to
appeal the decision.

A final progress report, invention statement, and Financial Status Report are
required upon either termination of an award or relinquishment of an award in
a change of institution situation.

INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS

For research projects involving human subjects, it is the policy of the NIH
that women and members of minority groups and their subpopulations must be
included in all NIH supported biomedical and behavioral research projects
involving human subjects unless a clear and compelling rationale and
justification is provided that inclusion is inappropriate with respect to the
health of the subjects or the purpose of the research.  This policy results
from the NIH Revitalization Act of 1993 (Section 492B of Public Law 103-43). 
All investigators proposing research involving human subjects should read the
"NIH Guidelines For Inclusion of Women and Minorities as Subjects in Clinical
Research," which has been published in the Federal Register of March 28,1994
(FR 59 14508-14513), and in the NIH Guide For Grants and Contracts, Volume 23,
Number 11, March 18, 1994. It is also available electronically at
http://www.nih.gov/grants/guide/1994/94.03.18/notice-nih-guideline008.html

Investigators may obtain copy of this policy from these sources or from the
program staff listed under INQUIRIES.

INCLUSION OF CHILDREN AS PARTICIPANTS IN RESEARCH INVOLVING HUMAN SUBJECTS

It is the policy of NIH that children (i.e., individuals under the age of 21)
must be included in all human subjects research, conducted or supported by
NIH, unless there are clear and compelling scientific and ethical reasons not
to include them. This policy applies to all initial (Type 1) applications
submitted for receipt dates after October 1, 1998.  All investigators
proposing research involving human subjects should read the "NIH Policy and
Guidelines on the Inclusion of Children as Participants in Research Involving
Human Subjects" that was published in the NIH Guide for Grants and Contracts,
March 6, 1998 and is available at the following URL address: 
http://www.nih.gov/grants/funding/children/children.htm

APPLICATION PROCEDURES

Applications are to be submitted on the grant application form PHS 398 (rev.
4/98) and should use the instructions in Section IV of the application kit. 
The application will be accepted at the standard application deadlines for
other K-awards as indicated in the application kit.  These receipt dates are
February 1, June 1, and October 1.  Application kits are available at most
institutional offices of sponsored research and from the Division of
Extramural Outreach and Information Resources, National Institutes of Health,
6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910, telephone 301-
435-0714, Email: grantsinfo@nih.gov.  The title and number of the announcement
must be typed in Section 2 of the face page of the application. The yes box
must be marked.  For those applicants with internet access, the 398 kit may be
found at: http://www.nih.gov/grants/funding/phs398/forms_toc.html

The completed original application and three legible copies must be sent or
delivered to:

Center for Scientific Review
National Institutes of Health
6701 Rockledge Drive, Room 1040 - MSC 7710
Bethesda, MD  20892-7710
(20817 for express service)

At the time of submission, two additional copies of the application must be
sent to:

Ms. Toby Friedberg
Referral Officer
Division of Extramural Activities
National Cancer Institute
Executive Plaza North, Room 636
6130 Executive Boulevard, MSC 7399
Rockville, MD 20850 (express courier)
Bethesda, MD 20892-7390

If an application is received after the deadline, it will be returned to the
applicant without review.  If the application submitted in response to this PA
is substantially similar to a grant application already submitted to the NIH
for review but has not yet been reviewed, the applicant will be asked to
withdraw either the pending application or the new one.  Simultaneous
submission of identical applications will not be allowed, nor will essentially
identical applications be reviewed by different review committees.  An
application, therefore, cannot be submitted in response to this PA which is
essentially identical to one that has already been reviewed.  This does not
preclude the submission of substantial revisions of applications already
reviewed, but such applications must include an introduction addressing the
previous critique.

The information summarized below must be provided in the application:

Candidate

o  Describe the candidate's commitment to an academic career in cancer
prevention, cancer control, epidemiology, or the behavioral/ population
sciences as these disciplines relate to cancer prevention and control;
o  Present evidence of the candidate's ability to interact and collaborate
with other scientists;
o  Discuss prior training and how it relates to the objectives and career
plans of the candidate;
o  Discuss the candidate's research efforts to this point in his/her research
career;
o  Letters of recommendation.  Three sealed letters of recommendation
addressing the above areas and any other evidence that the candidate has a
high potential for becoming an independent investigator in cancer research.

Career Development Plan

o  Present a systematic plan that covers the prior research training and
experience of the candidate to provide a basis for the need for further career
development to become an independent investigator.  The plan should provide a
description of the research and training experiences that will occur during
the K07 award period;
o  Document prior instruction in or propose plans for instruction in the
responsible conduct of research in terms of subject matter and duration of
instruction.  NO AWARD CAN BE MADE IF AN APPLICATION LACKS THIS COMPONENT.

Research Plan

o  Describe the research plan using Form PHS 398 (rev. 4/98 or subsequent
revisions) following instructions for the Specific Aims, Background and
Significance, Progress Report/Preliminary Studies, Research Design and
Methods.  The candidate should consult with the mentor regarding the
development of this section.  A sound research project that is consistent with
the candidate's level of research development must be provided.

Mentor's Statement

o  The application must include a statement from the mentor including
information on research qualifications and previous experience as a research
supervisor.  The application must also include a listing of the mentor's
active/pending research support related to the candidate's research plan and
nature of the supervision that will occur during the mentored phase of the
proposed award period;
o  Similar information must be provided by any co-mentor. If more than one
mentor is proposed, the respective areas of expertise and responsibility of
each should be described.

Environment and Institutional Commitment

o  Describe the resources and facilities that will be available to the
candidate;
o  Describe how the research environment of the institution is particularly
suited for the development of the candidate's research career and the pursuit
of the proposed research plan;
o  In a clear statement, provide assurances that the candidate will be able to
spend a minimum of 75 percent of his/her full-time professional effort in the
development of his/her research program, with the remaining percent effort
spent on activities related to the development of their research career.

Biographical Sketch

A biographical sketch is required for the applicant and all key personnel. 
Provide information on research projects completed and/or research grants
participated in during the last five years that are relevant to the proposed
project.

Budget

Applicants using a PHS 398 Form bearing the revision date 4/98 must follow the
instructions in the form.

REVIEW CONSIDERATIONS

Applications will be assigned on the basis of established PHS referral
guidelines.  Applications will be reviewed for completeness by the Center for
Scientific Review and for responsiveness to this program announcement by the
National Cancer Institute.  Incomplete or non-responsive applications will be
returned to the applicant without further consideration.  Applications that
are complete and responsive to the program announcement will be evaluated for
scientific and technical merit by an appropriate scientific review group
convened by the National Cancer Institute in accordance with the standard NIH
peer review procedures.  As part of the initial merit review, all applications
will receive a written critique, and may undergo a process in which only those
applications deemed to have the highest scientific merit, generally the top
half of applications under review, will be discussed, assigned a priority
score, and receive a second level review by the National Cancer Advisory
Board.

The following review criteria will be applied:

Candidate

o  Commitment of the candidate to an academic career in cancer prevention,
cancer control; epidemiology, or to the behavioral or population sciences as
these disciplines relate to cancer prevention and control;
o  Ability of the candidate to interact and collaborate with other scientists;
o  Quality of the prior scientific training and experience, including
publications that establish the innovativeness of the candidate's research and
a high potential for an independent research career;
o  Recommendations of three well-established scientists attesting to the
special potential of the individual to pursue an independent career in cancer
research.  The mentor's statement (see below) should not be included as one of
the letters of recommendation, although the mentor(s) may submit a separate
letter(s) of recommendation.

Career Development Plan

o  Likelihood that the plan will contribute substantially to the scientific
development of the candidate, based on:
- Candidate's prior training and research experience;
- Appropriateness of the goals and scope of the plan to complement prior
training/research experience and achieve the stated training and research
objectives;
o  Appropriateness of the proposed activities for the proposed award period;
o  Adequacy of prior or proposed training in the responsible conduct of
research.

Research Plan

o  Degree of relevance of the research plan to developing an independent
research program focused on cancer prevention, cancer control, epidemiology,
or the behavioral/population sciences as they relate cancer prevention and
control;
o  Usefulness of the research plan as a vehicle for enhancing existing
research skills as described in the career development plan;
o  The originality and quality of the research hypothesis/question, design and
methodology, judged in the context of the candidate's previous training and
experience.

Mentor/Co-Mentor (s)

o  Appropriateness of the mentor's research qualifications in the area of the
proposed research;
o  Previous experience in fostering the development of cancer researchers;
o  History of research productivity and peer reviewed support;
o  Adequacy of active/pending support for the proposed research project.

Environment and Institutional Commitment

o  Clear commitment of the institution to ensure that a minimum of 75 percent
of the candidate's full-time professional effort will be devoted directly to
research, with the remaining percent effort being devoted to activities
related to the successful development of a research career;
o  Adequacy of research facilities and training opportunities;
o  Quality and relevance of the environment for scientific and professional
development of the candidate.

Budget

o  Justification of the requested budget in relation to career development
goals and research aims and plans.

AWARD CRITERIA

Applications will compete for available funds with all other scored career
award applications received in response to this PA.  The following will be
considered in making decisions: quality of the proposed project as determined
by peer review, availability of funds and program balance.  The NCI will
notify the applicant of the National Cancer Advisory Board's (NCAB) action.

INQUIRIES

Inquiries are encouraged.  The opportunity to clarify any issues or questions
from potential applicants is welcome.

Direct inquiries regarding programmatic issues to:

Dr. Brian W. Kimes
Cancer Training Branch
Office of Centers, Training and Resources
National Cancer Institute
6116 Executive Blvd, Suite 7001
MSC 8346
Bethesda, MD  20892-8345
FAX:  (301) 402-0181
Email: bk34t@nih.gov

Inquiries regarding fiscal matters should be referred to:

Ms. Catherine Blount
Grants Administration Branch
National Cancer Institute
Executive Plaza South, Room 243
Bethesda, MD  20892
Telephone:  (301) 496-7800 ext. 262
FAX: (301) 496-8601
Email: cb136g@nih.gov

Direct inquiries regarding review matters to:

Ms. Toby Friedberg
Referral Officer
Division of Extramural Activities
National Cancer Institute
Executive Plaza North, Room 636
6130 Executive Boulevard-7407
Bethesda, MD 20892
Rockville, MD 20852-7407 (for express/courier service)
Telephone: (301) 496 -3428
FAX: (301) 402-0275
Email: tf12w@nih.gov

AUTHORITY AND REGULATIONS

This program is described in the Catalog of Federal Domestic Assistance No.
93.398, Cancer Research Manpower.  Awards are made under authorization of
Sections 301 and 405 of the Public Health Service Act as amended ( 42 USC 241
and 284) and administered under PHS grants policies and Federal Regulations 42
CFR 52 and 45 CFR Part 74 and Part 92.  This program is not subject to the
intergovernmental review requirements of Executive Order 12372 or Health
Systems Agency review.

The PHS strongly encourages all grant and contract recipients to provide a
smoke-free workplace and promote the non-use of all tobacco products.  In
addition, Public law 103-227, the Pro-Children Act of 1994, prohibits smoking
in certain facilities (or, in some cases, any portion of a facility) in which
regular or routine education, library, day care, health care or early
childhood development services are provided to children.  This is consistent
with the PHS mission to protect and advance the physical and mental health of
the American people.


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