DEVELOPING AND IMPROVING INSTITUTIONAL ANIMAL RESOURCES NIH GUIDE, Volume 22, Number 27, July 30, 1993 PAR NUMBER: PAR-93-102 P.T. 34 Keywords: Animal Breed. & Facil., Scientific Animal Research Policy National Center for Research Resources Application Receipt Date: October 1, 1993 PURPOSE The National Center for Research Resources (NCRR) encourages the submission of individual animal resource improvement grant applications from biomedical research institutions. Any domestic public or private institution, organization, or association is eligible to apply for this grant if the institution has one or more research projects supported by the Public Health Service (PHS) that involve the use of laboratory animals. The major objectives of this program are to upgrade animal facilities, develop administratively centralized programs of animal care, and enable institutions to comply with the USDA Animal Welfare Act and DHHS policies related to the care and use of laboratory animals. These awards require matching funds from the awardee institution. Support is limited to alterations and renovations (A&R) to improve laboratory animal facilities, and the purchase of major equipment items for animal resource, diagnostic laboratory, transgenic animal resources, or similar associated activities. ELIGIBILITY REQUIREMENTS Any domestic public or private institution, organization, or association is eligible to apply for this grant if it meets the above requirement. Institutions and commercial firms providing only services or products and without a clearly defined animal related research component are not eligible to apply. Also, this program will not support requests for equipment used for teaching purposes and for housing non-research animals. Applications from other Federal agencies or institutions (e.g., Department of Veterans Affairs) are limited to requests for equipment only. Applicants may not submit more than one application or apply for other NCRR support for developing and improving institutional animal resources in the same Federal fiscal year. For purposes of these guidelines, an "institution" is defined as the organizational component identified in item 14, form PHS 398 (rev. 9/91) page 1, for which descriptive information is provided on page 15 in the grant application form PHS 398 kit. Separate applications may be submitted from different colleges or schools on the same campus of a university within the same Federal fiscal year if they have different organizational component codes. If this is done, documentation from an appropriate institutional official, stating that the applications are part of a coordinated, campus-wide plan to improve the animal facilities, must be provided. The applicant institution is strongly encouraged to develop a single application for a campus-wide program with a single, centralized animal care program whenever possible or feasible. A separate grant program for animal facility improvement is available for research institutions receiving less than $1,500,000 (direct costs) of PHS support for research projects during the most recently completed Federal fiscal year. These institutions may, if they desire, compete for funding under either program, but not both in a single fiscal year. MECHANISM OF SUPPORT The mechanism available for the support of improvement projects is the Grant for Repair, Renovation, and Modernization of Existing Research Facilities (G20). Requests are limited to A&R to improve existing laboratory animal facilities, allowable fees associated with the A&R project, and major resource equipment related to the improvement project, such as animal cage systems and cage washers. Requests for new construction, including the completion of shell space, and equipment intended for teaching or non-research purposes are not allowable. Requests for basic general purpose equipment items for centralized surgeries, diagnostic laboratories, transgenic animal facilities, and other similar associated activities are allowable when well justified and integral to the proposed project. However, a single item of equipment or an aggregate of identical equipment items must have a total cost of at least $1,000. The total budget request for the improvement grant application and award is limited to $700,000 (direct costs), of which not more than $500,000 may be used for alterations and renovations. Matching funds from non-Federal sources are required, equal to or exceeding one-third of the total allowable costs (equipment and A&R) of the requested project ($2 Federal to $1 non-Federal). These matching funds must be applied to the specific project described in the application and cannot be met by citing other expenditures. Improvement grants are not intended to provide general operational support for the resource (e.g., funding for personnel, consumable supplies for routine animal care, or small equipment items) or to provide specialized research equipment or facilities for use by only a few investigators. Because the nature and scope of the proposed projects submitted in response to this announcement will vary, it is anticipated that the size of the awards will vary also. RESEARCH OBJECTIVES Animal resource improvement grants are awarded to assist biomedical research institutions in upgrading animal facilities and developing administratively centralized and uniformly effective programs of research animal care. Another major objective is to assist institutions in complying, and maintaining compliance, with provisions of the Animal Welfare Act and PHS policies related to the care and use of laboratory animals. APPLICATION PROCEDURES Applications are to be submitted on form PHS 398 (rev. 9/91). The single annual receipt date for these applications is October 1. Application forms may be obtained from the institutions office of sponsored research and from the Office of Grants Information, Division of Research Grants, National Institutes of Health, Westwood Building, Room 449, Bethesda, MD 20892, telephone (301) 710-0267. Applications received by this deadline will receive February/March initial peer review, May/June review by the National Advisory Research Resources Council, and will have an earliest possible award date of July 1. Applications received after the October 1 deadline will be returned to the applicant without review. Current guidelines for this program may be requested from the Laboratory Animal Sciences Program, CMP. These guidelines must be followed in detail. Applications not adhering to these guidelines will be considered non-responsive to this program and will be returned to the applicant without review. The completed original application (signed original including appendices, if any) and three copies must be sent or delivered to: Division of Research Grants National Institutes of Health Westwood Building, Room 240 Bethesda, MD 20892-4500** Simultaneously, two additional copies (with appendices, if any) must be sent under separate cover to: Scientific Review Administrator Comparative Medicine Review Committee National Center for Research Resources Westwood Building, Room 10A16 Bethesda, MD 20892-4500 REVIEW CONSIDERATIONS All applications will be reviewed for scientific and technical merit by an appropriate review committee managed by the Office of Review, NCRR. Second level review will be provided by the National Advisory Research Resources Council (NARRC). Review of the applications will be based on scientific merit, technical soundness, and cost effectiveness. Review criteria are listed in the supplemental program guidelines. AWARD CRITERIA Applications will compete with all other applications assigned to the Comparative Medicine Program, NCRR. An institution must have current PHS funding for research involving laboratory animals to be eligible for an award. The following will also be considered when making funding decisions: o Quality of the proposed project as determined by peer review o Institutional assurance of non-federal matching funds o Availability of funds INQUIRIES Inquiries about specific improvement program guidelines and detailed instructions for application are encouraged and may be directed to: Dr. Cynthia L. Pond Comparative Medicine Program National Center for Research Resources Westwood Building, Room 857 Bethesda, MD 20892 Telephone: (301) 594-7933 FAX: (301) 594-9149 Requests for guidelines must include two self-addressed mailing labels. Questions regarding fiscal matters may be directed to: Mr. Paul Karadbil Office of Grants and Contracts Management National Center for Research Resources Westwood Building, Room 849 Bethesda, MD 20892 Telephone: (301) 594-7955 AUTHORITY AND REGULATIONS This program is described in the Catalog of Federal Domestic Assistance No. 93.306, Laboratory Animal Sciences and Primate Research. Awards will be made under the authority of the Public Health Service Act, Title III, Section 301 (Public Law 78.410, as amended; 42 USC 241) and administered under PHS grants policies and Federal Regulations 42 CFR Part 52 and 45 CFR Part 74. This program is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review. .
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