NIH GUIDE, Volume 21, Number 29, August 14, 1992

PA NUMBER:  PA-92-97

P.T. 34


  Animal Breed. & Facil., Scientific 

National Center for Research Resources

Application Receipt Date:  October 1, 1992


The National Center for Research Resources (NCRR) assists institutions

in developing, modernizing, and improving animal resources for

biomedical research and research training by awarding research and

resource grants.  Animal resource improvement grants (G20) are awarded

for this purpose and to assist institutions in complying with the

provisions of the Animal Welfare Act and Public Health Service (PHS)

policies related to the care and use of laboratory animals.  Requests

are limited to alterations and renovations (A&R) and to purchases of

major animal resource equipment (with a unit value of at least $1,000).

Support for new construction, including completion of shell space, is

not authorized.  Projects may address improvement of animal facilities

and related activities, including centralized experimental surgical

facilities, diagnostic laboratories, and transgenic animal resources.


Any domestic public or private institution, organization, or

association with one or more research projects supported by the PHS

that involve the use of laboratory animals is eligible to apply.

Institutions and commercial firms providing only services or products

and without a clearly defined animal related research component are not

eligible to apply.  Also, this program will not support requests for

equipment used for teaching purposes and for housing non-research

animals.  Applicants may not submit more than one application or apply

for other NCRR support for developing and improving institutional

animal resources in the same Federal fiscal year.

There is a separate program and guidelines for animal facility

improvement grant applications from small research institutions

receiving less than $1,000,000 (direct costs) of PHS support for

research projects during the most recently completed Federal fiscal

year (refer to PA-92-10 that was published in the NIH Guide for Grants

and Contracts, Vol. 20, No. 39, October 18, 1991).


The mechanism available for the support of improvement projects is the

Grant for Repair, Renovation, and Modernization of Existing Research

Facilities (G20).  Requests are limited to A&R to improve existing

laboratory animal facilities, allowable fees associated with the A&R

project, and major resource equipment related to the improvement

project, such as animal cage systems and cage washers.  Equipment

requests must have a manufacturer's unit value of at least $1,000.

Requests for basic general purpose equipment items for centralized

surgeries, diagnostic laboratories, transgenic animal facilities, and

other similar associated activities are allowable when well justified

and integral to the proposed project.  The total budget request for the

improvement grant application and award is limited to a total of

$700,000 (direct costs), of which not more than $500,000 may be used

for alterations and renovations.  Matching funds from non-Federal

sources, equal to or exceeding one-half of the total award ($2 Federal

to $1 non-Federal), are required.


Animal resource improvement grants are awarded to assist biomedical

research institutions in upgrading animal facilities and developing

administratively centralized and uniformly effective programs of animal

care.  Another major objective is to assist institutions in complying,

and maintaining compliance, with provisions of the Animal Welfare Act

and PHS policies related to the care and use of laboratory animals.


Applications are to be submitted on form PHS 398, "Application for

Public Health Service Grant," (rev. 9/91) to the NIH Division of

Research Grants.  The single annual receipt date for applications in

response to this announcement is October 1.  Applications received by

this deadline will receive February/March initial peer review, May/June

review by the National Advisory Research Resources Council, and will

have an earliest possible award date of July 1.  Applications received

after the October 1 deadline will be returned to the applicant without


The completed original application (signed original including

appendices, if any) and three copies must be sent or delivered to:

Grant Application Receipt Office

Division of Research Grants

National Institutes of Health

Westwood Building, Room 240

Bethesda, MD  20892-4500**

Simultaneously, two additional copies (with appendices, if any) must be

sent under separate cover to:

Scientific Review Administrator

Comparative Medicine Review Committee

Office of Review

National Center for Research Resources

Westwood Building, Room 10A16

Bethesda, MD  20892-4500**

Application forms (PHS 398) may be obtained from grantee business or

sponsored projects offices and from the Office of Grants Inquiries,

Division of Research Grants, National Institutes of Health, Westwood

Building, Room 449, 5333 Westbard Avenue, Bethesda, MD 20892-4500,

telephone: (301) 496-7441.


All applications will be reviewed for scientific and technical merit by

an appropriate review committee managed by the Office of Review, NCRR.

Second level review will be provided by the National Advisory Research

Resources Council.  Review of the applications will be based on

scientific merit, technical soundness, and cost effectiveness.


Applications will compete for available funds with all other

applications assigned to the Comparative Medicine Program, NCRR.  The

following will be considered when making funding decisions:

o  Quality of the proposed project as determined by peer review

o  Institutional assurance of non-federal matching funds

o  Availability of funds


Inquiries about specific improvement program guidelines and detailed

instructions for application and other aspects of the program are

encouraged and are to be directed to the following address (requests

for guidelines must include two self-addressed mailing labels):

Director, Laboratory Animal Science Program

Comparative Medicine Program

National Center for Research Resources

Westwood Building, Room 857

5333 Westbard Avenue

Bethesda, MD  20892-4500

Telephone:  (301) 496-5175

FAX:  (301) 480-0868

Questions regarding fiscal matters are to be directed to:

Mr. Paul Karadbil

Supervisory Grants Management Specialist

Office of Grants and Contracts Management

National Center for Research Resources

Westwood Building, Room 849

Bethesda, MD  20892-4500

Telephone:  (301) 496-9840


This program is described in the Catalog of Federal Domestic Assistance

No. 93.306, Laboratory Animal Sciences and Primate Research.  Awards

will be made under the authority of the Public Health Service Act,

Title III, Section 301 (Public Law 78.410, as amended; 42 USC 241) and

administered under PHS grants policies and Federal Regulations 42 CFR

Part 52 and 45 CFR Part 74.  This program is not subject to the

intergovernmental review requirements of Executive Order 12372 or

Health Systems Agency review.


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