Part I Overview Information


Department of Health and Human Services     

Participating Organizations
National Institutes of Health (NIH), (http://www.nih.gov/)

Components of Participating Organizations
National Institute on Alcohol Abuse and Alcoholism (NIAAA), (http://www.niaaa.nih.gov/)
National Institute on Drug Abuse (NIDA), (http://www.nida.nih.gov/)

Title: Senior Scientist Research and Mentorship Award (K05)

Announcement Type

This is a modification of PA-00-021 which was previously released on December 2, 1999.

Update: The following update relating to this announcement has been issued:

Looking ahead: As part of the Department of Health and Human Services' implementation of e-Government, during FY 2006 the NIH will gradually transition each research grant mechanism to electronic submission through Grants.gov and the use of the SF 424 Research and Related (R&R) forms. Therefore, once the transition is made for a specific grant mechanism, investigators and institutions will be required to submit applications electronically using Grants.gov. For more information and an initial timeline, see http://era.nih.gov/ElectronicReceipt/. NIH will announce each grant mechanism change in the NIH Guide to Grants and Contracts (http://grants.nih.gov/grants/guide/index.html). Specific funding opportunity announcements will also clearly indicate if Grants.gov submission and the use of the SF424 (R&R) is required. Investigators should consult the NIH Forms and Applications Web site (http://grants.nih.gov/grants/forms.htm) for the most current information when preparing a grant application.

Program Announcement (PA) Number: PA-06-555

Catalog of Federal Domestic Assistance Number(s):
93.271; 93.279

Key Dates
Release Date:  September 20, 2006
Letters of Intent Submission Date(s):  Not applicable
Application Submission Date(s): http://grants.nih.gov/grants/funding/submissionschedule.htm
AIDS Application Submission Date(s): http://grants1.nih.gov/grants/funding/submissionschedule.htm#AIDS
Peer Review Date(s): http://grants.nih.gov/grants/funding/submissionschedule.htm
Council Review Date(s): http://grants.nih.gov/grants/funding/submissionschedule.htm
Earliest Anticipated Start Date(s): http://grants.nih.gov/grants/funding/submissionschedule.htm
Additional Information To Be Available
(URL Activation Date):  Not applicable
Expiration Date:  September 2, 2009 (Now Expired January 14, 2009 per PA-09-076)

Due Dates for E.O. 12372
Not Applicable

Executive Summary

Table of Contents


Part I Overview Information

Part II Full Text of Announcement

Section I. Funding Opportunity Description
    1. Research Career Objectives

Section II. Award Information
    1. Mechanism of Support
    2. Funds Available

Section III. Eligibility Information
    1. Eligible Applicants
      A. Eligible Institutions
      B. Eligible Individuals
    2. Cost Sharing or Matching
    3. Other - Special Eligibility Criteria

Section IV. Application and Submission and Instructions
    1. Address to Request Application Information
    2. Content and Form of Application Submission
    3. Submission Dates and Times
      A. Submission, Review and Anticipated Start Dates
        1. Letter of Intent
      B. Sending an Application to the NIH
      C. Application Processing
    4. Intergovernmental Review
    5. Funding Restrictions
    6. Other Submission Requirements

Section V. Application Review Information
    1. Criteria
    2. Review and Selection Process
      A. Additional Review Criteria
      B. Additional Review Considerations
      C. Sharing Research Data
      D. Sharing Research Resources  
    3. Anticipated Announcement and Award Dates

Section VI. Award Administration Information
    1. Award Notices
    2. Administrative and National Policy Requirements
    3. Reporting

  Section VII. Agency Contacts
    1. Scientific/Research Contacts
    2. Peer Review Contacts
    3. Financial/ Grants Management Contacts

  Section VIII. Other Information - Required Federal Citations


Part II - Full Text of Announcement


Section I. Funding Opportunity Description


1. Research Career Objectives

The Senior Scientist Research and Mentorship Award (K05) is intended to provide outstanding senior scientists protected time to focus on and enhance their research and to carry out mentoring of new investigators.  Candidates for the Senior Scientist Research and Mentorship Award (K05) should be recognized leaders in the alcohol, or drug abuse, or related research fields who have demonstrated a sustained, high level of productivity and a distinguished record of original contributions in their field, and whose expertise and contributions to these research fields will continue to be critical to the missions of the NIAAA or NIDA. Each candidate must demonstrate both the need for protected time to further their field of research and a commitment to serve as a mentor to new investigators or junior faculty who are currently performing or will begin to perform alcohol, or drug abuse, or related research. Mentored investigators should have an independent, full-time appointment at their institution; this can be in either non-tenure or tenure-track positions. The award provides 75 percent salary support for the K05 applicant for up to five years and may be renewed for one additional five-year period.  The applicant must commit a total of 75 percent effort to the proposed program, with at least 25 percent of that effort to the mentoring activities proposed under this award. K05 applicants are expected to have independent, peer-reviewed research grant funding (such as an R01, P01, U01, or an equivalent grant in excess of $125,000 direct costs per year) at the time of submitting the K05 application to support the proposed research activities.  An exception may be considered if the applicant is conducting primarily theoretical work. Additional funds will not be provided to support the applicant’s research or research activities. However in keeping with the objectives of this program, NIAAA will provide up to $25,000 per year (based on approximately $5,000 allowed per mentee and a total of 5 mentored investigators) for the benefit of the mentored junior investigators to support expenses incurred in performing activities directly resulting from mentoring recommendations. NIDA will provide up to $25,000 per year for research-related and/or mentoring support only for investigators who are engaged in predominantly theoretical research, such as modeling or computer simulation. Both NIAAA and NIDA will require the sponsoring institution to ensure that the K05 applicant has the protected time needed to conduct the proposed program including mentoring activities.

The NIAAA and NIDA acknowledge the following in offering the Senior Scientist Research and Mentorship Award (K05).

First, the NIAAA and NIDA are committed to the development of the next generation of exceptionally talented new scientists who are committed to conducting basic, clinical and/or behavioral research on the health risks and benefits of alcohol consumption, or the health risks of drug abuse, and the prevention and treatment of alcohol, or drug abuse, or related disorders. Towards this goal, NIAAA and NIDA support several programs designed to address the research training and career development needs of alcohol [http://www.niaaa.nih.gov/ResearchInformation/ExtramuralResearch/default.htm] and of drug abuse [http://www.niaaa.nih.gov/ResearchInformation/ExtramuralResearch/default.htm] researchers, respectively. However, mentoring and supervision should continue beyond these programs. New investigators and junior faculty members may also achieve benefits from mentoring as they begin to establish their own research programs. These junior, independent investigators are potential innovators of the future. They will bring fresh ideas and technologies to tackle biomedical and behavioral research problems, and will pioneer new areas of investigation. NIAAA and NIDA believe that junior investigators can benefit from skilled advice and guidance - such as can be provided by senior scientists - as they establish their own independent research programs; from strategizing scientific problems and developing research directions to obtaining guidance in grant writing skills and identifying funding opportunities in their pursuit of independent grant support for their research ideas and interests.

Second, NIAAA and NIDA recognize the achievements that outstanding senior scientists have made in alcohol, or drug abuse, and related research and encourage the continued productivity of these investigators. NIAAA and NIDA also recognize that senior scientists have much to offer new investigators. Therefore, NIAAA and NIDA offer the Senior Scientist Research and Mentorship Award as a mechanism to provide recognized and well-respected leaders in alcohol, or drug abuse, or related research with protected time to continue and enhance their research programs and to disseminate their expertise and wisdom in the mentoring of junior investigators. In addition to their proposed research activities, the applicant will be expected to commit to mentoring from two to five junior investigators through this award. Senior scientists in all areas of alcohol, or drug abuse, or related research are encouraged to apply for this award.

See Section VIII, Other Information - Required Federal Citations, for policies related to this announcement.

Section II. Award Information


1.Mechanism of Support

This funding opportunity will use the NIH K05 award mechanism. As an applicant, you will be solely responsible for planning, directing, and executing the proposed research career development and mentoring activities.

This funding opportunity uses the just-in-time budget concepts. It also uses the non-modular budget format described in the PHS 398 application instructions (see http://grants.nih.gov/grants/funding/phs398/phs398.html). The applicant should follow the instructions for budget information described in the PHS 398, Section III, providing only the total direct costs requested for each year and for the entire proposed period of support, and the supporting budget justification information.

The K05 project award period may be from three to five years. Awards are renewable for one additional project period of up to five years for all K05 award recipients. New (Type 1) K05 applications submitted by investigators who have received a previous K05 award from any NIH Institute other than NIAAA or NIDA will fall under the same guidelines as other new K05 applications. Awards are not transferable from one principal investigator to another.

2. Funds Available

NIAAA and NIDA anticipate supporting from 2 - 5 new (Type 1) K05 awards each per year. The total amount to be awarded under the K05 program and the number of anticipated awards will depend upon the quality, duration, and costs of the applications received, the availability of funds, and the program priorities of the appropriate institute.

Because the nature and scope of the proposed career development and research mentoring program will vary from application to application, it is anticipated that the size and duration of each award will also vary. Awards include funds for salary, fringe benefits, and mentored-training support.

ALLOWABLE COSTS

Salary:  The Senior Scientist Research and Mentorship Award (K05) will provide salary for the award recipient of 75 percent of the recipient’s base salary up to the salary cap. The salary cap for NIAAA awards will be up to the current maximum Federally-legislated salary rate in effect at the time of the award per year for up to five years. The salary cap for NIDA awards is $90,000 for each award year. The actual salary provided by the award is based on the recipient’s institutional base salary for a full-time, 12-month staff appointment. The award requires the candidate to devote 75 percent of full-time professional effort towards conducting the experimental research plan and the mentoring activities described in the application. For information regarding NIH policy in determining full-time professional effort for career awards, see http://grants.nih.gov/grants/guide/notice-files/NOT-OD-04-056.html.

The salary must be consistent both with the established salary structure at the institution and with salaries actually provided by the institution from its own funds to other staff members of equivalent qualifications, rank, and responsibilities in the department concerned. If full-time, 12-month salaries are not currently paid to comparable staff members, the salary proposed must be appropriately related to the existing salary structure. Confirmation of salary is required prior to the issuance of an award. The award will also provide fringe benefits on the calculated base salary based on the sponsoring institution’s established rate.

The sponsoring institution may supplement the NIH salary contribution up to a level that is consistent with the institution’s salary scale. However, institutional supplementation of salary must not require extra duties or responsibilities that would interfere with the purpose of the K05 award, and, in no case may PHS funds be used for salary supplementation. 

Recipients of a NIAAA K05 award may also derive additional salary compensation from the effort associated with all other federal sources or awards, including any NIH research grant, provided the total salary derived from all Federal sources does not exceed the current legislatively-mandated Federal salary rate limit, and their total percent effort on all federal sources and awards does not exceed 100 percent. Direct salary is exclusive of fringe benefits, indirect costs/facilities, and administrative expenses. Note that NIDA does not allow additional salary compensation from other federal sources. 

Research Support:  It is expected that candidates for a K05 award will have sufficient, independent research support to conduct their proposed research. Therefore, additional funds to support the research or research activities of the candidate will not be provided under this award.

Mentored Training Support: NIAAA will provide up to $25,000 per year to support expenses incurred by the mentored investigators in performing activities directly resulting from mentoring recommendations. NIDA will provide up to $25,000 per year for research-related and/or mentoring expenses of only those mentored investigators who are engaged in predominantly theoretical research. The amount requested should be based on up to $5,000 allowed per mentee and a maximum of 5 mentored investigators per year. Note that it is expected that the candidate will mentor between two to five junior investigators per year. Expenses could include: (a) tuition and course fees, (b) travel to research meetings or to obtain training, or c) research supplies and equipment for the mentored investigators.  Funds provided for mentoring expenses can not be rebudgeted for any other purpose.

Ancillary Personnel Support:  Salary support for secretarial or administrative assistance, or for other ancillary personnel, is not allowed. 

Facilities and Administrative (F&A) Costs:  These costs, which were formerly called indirect costs, will be reimbursed at 8% of modified total direct costs exclusive of tuition and fees, and of expenditures for equipment.

Section III. Eligibility Information


1. Eligible Applicants

1.A. Eligible Institutions  

You may submit (an) application(s) if your organization has any of the following characteristics:

Foreign institutions are not eligible to apply.

1.B. Eligible Individuals

Any individual with the skills, knowledge, and resources necessary to carry out the proposed research and mentoring activities is invited to work with their institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are further encouraged to apply for NIH support. The following additional eligibility requirements are specific to individuals who seek to become Senior Scientist Research and Mentorship Award (K05) recipients.

Only U.S. citizens or non-citizen nationals, or individuals lawfully admitted for permanent residence who possesses an Alien Registration Receipt Card (I-151 or I-551), or some other verification of legal admission as a permanent resident prior to the time of award, are eligible for this award.  Non-citizen nationals, although not U.S. citizens, owe permanent allegiance to the U.S.  They are usually born in lands that are not states but are under U.S. sovereignty, jurisdiction, or administration.  Individuals on temporary or student visas are not eligible.

The candidate for the Senior Scientist Research and Mentorship Award must be an outstanding senior basic, clinical or behavioral research investigator and a recognized leader in the alcohol, drug abuse, or related research fields with a distinguished record of original contributions, must have a record of obtaining external grant support from a funding institute or center, and is expected to have peer-reviewed grant support from any federal agency at the time of submitting the K05 application. Scientists whose work is primarily theoretical may apply for this award in the absence of research grant support.  Candidates for this award must have a research or health-professional doctoral degree or its equivalent.  Such degrees include but are not limited to the Ph.D., M.D., D.O., D.D.S., D.M.D., O.D., D.C., D.S.W., D.P.H., Pharm.D., as well as a doctoral degree in nursing research or practice.  

The candidate must have a “full-time” appointment at the academic institution that is the applicant institution.  Candidates who have VA appointments may not consider part of the VA effort towards satisfying the “full-time” requirement at the applicant institution.

2. Cost Sharing or Matching

This program does not require cost sharing as defined in the current NIH Grants Policy Statement.  The most current Grants Policy Statement can be found at: http://grants.nih.gov/grants/policy/nihgps_2003/nihgps_Part2.htm#matching_or_cost_sharing

3. Other-Special Eligibility Criteria

A candidate for a K05 Award may not simultaneously submit or have an application pending for any other PHS career development (K series) award nor any PHS award that duplicates any of the provisions of the K05 award. While current recipients of a NIH career development award are eligible to apply, an individual may not hold concurrent career development awards.

Key elements and common aspects that will be considered for each application include:

A. Candidate:  The candidate must be an outstanding, well-respected senior scientist in the alcohol, drug abuse, or related research fields with a distinguished record of original publications and external grant support. The candidate is expected to have peer-reviewed, independent research support from any federal agency at the time of submitting a new (Type 1) K05 application. Eligible research grant support includes investigator-initiated research project (R01) grants, P01 grants, center grants, cooperative agreement (U01) awards, or similar NIH grants supported in excess of $125,000 direct costs per year, and comparable awards from other granting agencies. NIH small research grants (R03), NIH exploratory/developmental grants (R21), or small grants of less than $100,000 direct costs per year from other granting agencies are not considered independent support for purposes of eligibility to apply for K05 award support. However, current NIAAA or NIDA K05 award recipients who are submitting a renewal (Type 2) application must have been awarded a research grant (R01), center grant, P01 grant, or cooperative agreement (U01) award from the K05 awarding Institute at the time of renewal submission. Note that former awardees of K05 grants from a NIH Institute other than NIAAA or NIDA are eligible to submit a new (Type 1) application in response to this announcement. These applications will be subject to the same responsiveness criteria and guidelines as other new K05 applications.

One exception to the requirement for peer-reviewed, independent research support is made for scientists whose work is primarily theoretical. These individuals may apply for a K05 award in the absence of research grant support if the institutional commitment includes stability of salary and research support, and the candidate’s record of publications, recognition of scientific leadership and capacity for mentoring are strong.

The candidate should demonstrate a strong track record of mentoring new investigators and junior researchers.

Candidates must be able to demonstrate the need for a period of intensive research focus as a means of enhancing their research career and a need for protected time to conduct their mentoring activities.

B. Research Activities:  It is expected that the award recipient will devote all professional effort described under this award that is not spent on mentoring activities to sustaining and improving their own research programs. This includes activities that will ensure continued outstanding performance and research capacity in alcohol, drug abuse, or related research.

C. Mentoring Activities:  It is expected that the award recipient will spend at least twenty-five (25) percent of full-time professional effort on mentoring activities. It is further expected that the recipient will mentor from two to five new or junior investigators as part of the award. New or junior investigators include those individuals who hold an independent, full-time position at their institution; this can be in either non-tenure or tenure-track faculty positions. Junior investigators may or may not have conducted alcohol or drug abuse research in the past, but are expected to perform alcohol, drug abuse, or related research under the tutelage of the award recipient during the award period.

D.  Environment:  The institution must be able to demonstrate a commitment to the K05 applicant as a productive, independent scientist, and that the applicant is an integral part of its research and academic program. The applicant and institution must certify that the applicant will be released from other duties to enable the applicant to devote 75 percent effort to achieve the research and mentoring objectives of this award. The applicant and institution must assure that there is an adequate pool of candidates for mentoring.

Section IV. Application and Submission Information


1. Address to Request Application Information

The PHS 398 application instructions are available at http://grants.nih.gov/grants/funding/phs398/phs398.html in an interactive format. Applicants must use the currently approved version of the PHS 398. For further assistance contact Grants Info, Telephone (301) 435-0714, Email: GrantsInfo@nih.gov.

Telecommunications for the hearing impaired: TTY 301-451-5936.

2. Content and Form of Application Submission

Applications must be prepared using the PHS 398 research grant application instructions and forms.  Applications must have a Dun and Bradstreet (D&B) Data Universal Numbering System (DUNS) number as the universal identifier when applying for Federal grants or cooperative agreements. The D&B number can be obtained by calling (866) 705-5711 or through the web site at http://www.dunandbradstreet.com/The D&B number should be entered on line 11 of the face page of the PHS 398 form.

See also Subsection VI.2. for additional information.

The title and number of this funding opportunity:”PA-06-xxx Senior Scientist Research and Mentorship Award (K05)”; must be typed on line 2 of the face page of the application form and the YES box must be checked.

SUPPLEMENTARY INSTRUCTIONS for Career Development awards are located in the PHS 398, Section III.

3. Submission Dates and Times

See Section IV.3.A for details.

3.A. Submission, Review and Anticipated Start Dates

Letters of Intent Submission Date(s): Not applicable.
Application Submission Date(s): http://grants.nih.gov/grants/funding/submissionschedule.htm
AIDS Application Submission Date(s): http://grants1.nih.gov/grants/funding/submissionschedule.htm#AIDS Peer Review Date(s): http://grants.nih.gov/grants/funding/submissionschedule.htm
Council Review Date(s): http://grants.nih.gov/grants/funding/submissionschedule.htm
Earliest Anticipated Start Date(s): http://grants.nih.gov/grants/funding/submissionschedule.htm

3.A.1. Letter of Intent

 A letter of intent is not required for this funding opportunity.

3.B. Sending an Application to the NIH

Applications must be prepared using the PHS 398 research grant application instructions
and forms as described above. Submit a signed, typewritten original of the application, including the checklist, and five signed photocopies in one package to:

Center for Scientific Review
National Institutes of Health
6701 Rockledge Drive, Room 1040, MSC 7710
Bethesda, MD 20892-7710 (U.S. Postal Service Express or regular mail)
Bethesda, MD 20817 (for express/courier service; non-USPS service)

Personal deliveries of applications are no longer permitted (see http://grants.nih.gov/grants/guide/notice-files/NOT-OD-03-040.html).

3.C. Application Processing

Applications must be submitted on or before the application receipt/submission dates described above (Section IV.3.A.) and at http://grants.nih.gov/grants/dates.htm.  Upon receipt, applications will be evaluated for completeness by CSR.  Incomplete applications will not be reviewed.

The NIH will not accept any application in response to this funding opportunity that is essentially the same as one currently pending initial merit review unless the applicant withdraws the pending application. The NIH will not accept any application that is essentially the same as one already reviewed. This does not preclude the submission of a substantial revision of an application already reviewed, but such application must include an Introduction addressing the previous critique.

Information on the status of an application should be checked by the Principal Investigator in the eRA Commons at: https://commons.era.nih.gov/commons/.

4. Intergovernmental Review

This initiative is not subject to intergovernmental review.

5. Funding Restrictions

All awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement. The Grants Policy Statement can be found at http://grants.nih.gov/grants/policy/policy.htm.

Pre-Award Costs are allowable. A grantee may, at its own risk and without NIH prior approval, incur obligations and expenditures to cover costs up to 90 days before the beginning date of the initial budget period of a new or competing renewal award if such costs: are necessary to conduct the project, and would be allowable under the grant, if awarded, without NIH prior approval. If specific expenditures would otherwise require prior approval, the grantee must obtain NIH approval before incurring the cost. NIH prior approval is required for any costs to be incurred more than 90 days before the beginning date of the initial budget period of a new or competing renewal award.

The incurrence of pre-award costs in anticipation of a competing or non-competing award imposes no obligation on NIH either to make the award or to increase the amount of the approved budget if an award is made for less than the amount anticipated and is inadequate to cover the pre-award costs incurred. NIH expects the grantee to be fully aware that pre-award costs result in borrowing against future support and that such borrowing must not impair the grantee's ability to accomplish the project objectives in the approved time frame or in any way adversely affect the conduct of the project. See NIH Grants Policy Statement http://grants.nih.gov/grants/policy/nihgps_2003/NIHGPS_Part6.htm.

6. Other Submission Requirements

Applications must be prepared as described by the PHS 398 research grant application instructions for career development awards. However, Letters of Reference and Statements by Sponsor(s) are not required. The following provides additional guidance for addressing the requirements of the K05 Senior Scientist Research Mentoring Award.

Budget

Budget requests should be prepared according to the instructions in form PHS 398. Provide only the total direct costs for each year and for the entire proposed period of support. In addition within the direct costs limitations of up to $25,000 for mentoring support for all NIAAA K05 awards or $25,000 for research-related and/or mentoring support only for theoretical investigators on NIDA K05 awards, provide a description of all potential courses, supplies, equipment or other mentoring costs that could be used to facilitate and achieve the mentoring objectives of this award.

Candidate

Candidates should describe their research experiences to date, including their scientific skills and accomplishments and their record of research grant support. Please note that candidates are expected to have current peer-reviewed research grant support at the time of application. Candidates should also provide a narrative describing their long-term research and career objectives.

Since mentoring is an essential component of the K05 award, candidates should describe their past and current involvement in mentoring new and junior investigators. This information should include the number of past and current mentored investigators, the scientific and professional backgrounds of these mentored investigators, the candidate’s role in their mentoring (e.g. research advisor, clinical mentor), and a description of the specific scientific projects that were pursued while under mentorship. To further judge the success of past mentoring, the candidate may list relevant research accomplishments, scientific publications, and the ability to obtain external grant support by their mentees, and provide any other information that describes how the candidate’s mentoring activities enhanced the career development of the mentored investigators.

Research Activities

The candidate must provide evidence of a continuing and productive commitment to a research career that is relevant to the mission of NIAAA or NIDA by submitting a statement of research career interests, including short-term and long-term research goals, and a description of specific activities that will sustain the candidate’s outstanding performance and the capacity to address relevant research problems. The candidate should also explain how the award will benefit the candidate by release from duties unrelated to research. It is important to convey the need for protected time to pursue a vital research program and to engage in the mentoring of new scientists.

Mentoring Plan

The mentoring plan should include a description of the institutional setting as it pertains to the available pool of potential junior investigators from which the mentees will be selected. The candidate should identify the initial group of junior investigators to be mentored, including a brief description outlining the previous training and specialization of these individuals, the frequency and kinds of mentoring activities to be conducted for each individual, and the proposed period of interaction between the candidate and mentee. The mentoring plan should provide details on the recruitment, selection and supervision of additional junior investigator(s) and an estimate of the total number of junior investigators expected to be mentored over the course of the award period.  Candidates should seek to promote diversity in their mentoring relationships by recruiting individuals from underrepresented racial and ethnic groups, individuals with disabilities, and individuals from disadvantaged backgrounds. K05 award candidates should describe any financial and material support from their own funded research and research resources that will be available to their mentees, and provide any other information concerning their roles as mentors to junior faculty. The candidate’s proposed percent commitment to the mentoring plan should also be stated.

Environment and Institutional Commitment

Evidence should be provided of institutional commitment for enhancing the candidate’s research program and mentoring activities. The K05 application should include a description of facilities and resources available to the candidate and their appropriateness for the candidate’s proposed research and mentoring activities. The applicant should describe the duties and responsibilities at the institution that will be relieved of to focus on the research and mentoring activities proposed under this award. Also include how the institution will accommodate these activities through other institutional personnel and resources. Institutional officials must submit supporting written documentation on the commitment from the Institution in providing the candidate with protected time for research and mentoring activities. 

Training in the Responsible Conduct of Research

Applications must include a description of a program to provide formal or informal instruction in the responsible conduct of research. Applications without plans for instruction in the responsible conduct of research will be considered incomplete and may be returned to the applicant without review. Although the NIH does not establish specific curricula or formal requirements, all programs are encouraged to consider instruction in the following areas: conflict of interest, responsible authorship, and policies for handling misconduct policies regarding the use of human and animal subjects and data management. Applicants must follow the application instructions found on page 49 of the PHS-398 application package and refer to the NIH website (http://bioethics.od.nih.gov/) for additional guidance.

Applications should document prior instruction, or proposed plans for training, in the responsible conduct of research for the candidate and all mentees, including subject matter and duration of instruction.

Plan for Sharing Research Data

A plan for sharing research data is not required.

Sharing Research Resources

NIH policy requires that grant awardee recipients make unique research resources readily available for research purposes to qualified individuals within the scientific community after publication (NIH Grants Policy Statement http://grants.nih.gov/grants/policy/nihgps_2003/index.htm and http://grants.nih.gov/grants/policy/nihgps_2003/NIHGPS_Part7.htm#_Toc54600131). Investigators responding to this funding opportunity should include a plan for sharing research resources addressing how unique research resources will be shared or explain why sharing is not possible.

The adequacy of the resources sharing plan will be considered by Program staff of the funding organization when making recommendations about funding applications. The effectiveness of the resource sharing will be evaluated as part of the administrative review of each non-competing Grant Progress Report (PHS 2590, http://grants.nih.gov/grants/funding/2590/2590.htm). See Section VI.3. Reporting.

Section V. Application Review Information


1. Criteria (Update: Enhanced review criteria have been issued for the evaluation of research applications received for potential FY2010 funding and thereafter - see NOT-OD-09-025).

Only the review criteria described below will be considered in the review process.

2. Review and Selection Process

Applications submitted for this funding opportunity will be assigned to a Scientific Review Group on the basis of established PHS referral guidelines.

Appropriate scientific review groups convened in accordance with the standard NIH peer review procedures (http://www.csr.nih.gov/refrev.htm) will evaluate applications for scientific and technical merit.

As part of the initial merit review, all applications:

Applications will compete for available funds with all other approved career development award applications. The following will be considered in making funding decisions:

REVIEW CRITERIA

The goals of NIH-supported research career development programs are to help ensure that diverse pools of highly trained scientists are available in adequate numbers and in appropriate research areas to address the Nation’s biomedical, behavioral, and clinical research needs.  The scientific review group will address and consider each of these criteria in assigning the application's overall score, weighting them as appropriate for each application. 

The application does not need to be strong in all categories to receive a high priority score. These criteria are listed in logical order and not in order of priority. 

Candidate

What is the quality of the candidate’s academic and research record? Has the candidate shown leadership of a productive alcohol, drug abuse, or related research program, and is the candidate recognized as a leader in the respective research field?  Is there evidence of a consistent and ongoing record of outstanding research productivity as demonstrated by success in obtaining external research grant funding and the publication of high-impact scientific reports, including publication of influential research papers or seminal theoretical papers? Does the candidate have a strong track record in mentoring or training junior investigators?

Research Activities

Is there evidence that the award will provide the candidate with protected time in order to focus on research and mentoring activities, and will permit release from teaching, administrative, clinical, and other non-research related responsibilities? Is there evidence that the award will enable the candidate to continue to sustain outstanding performance and research capacity in addressing scientific problems of importance to alcohol, drug abuse, or related research? Is there the likelihood that the candidate will continue to make significant contributions to scientific knowledge? Does the candidate have external support to conduct the proposed research activities?

Mentoring Plan

Does the candidate have the appropriate experience and potential to serve as a mentor to new investigators and junior faculty? Does the candidate have the experience and capability to develop and maintain a high quality environment for training and mentoring investigators? Is the mentoring plan adequate in describing how the candidate will mentor junior investigators and provide assistance in the development of their careers in alcohol, drug abuse, or related research? Has the candidate committed an appropriate level of effort to conduct the proposed mentoring activities?

Environment and Institutional Commitment

What is the quality and relevance of the institutional facilities and general environment as it relates to the proposed research and mentoring activities? Do the applicant institution and the candidate’s department have a reputation as a center of active, high-quality research? Is the applicant institution clearly committed to supporting the candidate’s research and mentoring activities proposed under this award, including providing space, facilities and other resources that may be essential for this program?

2.A. Additional Review Criteria:

In addition to the above criteria, the following items will continue to be considered in the determination of scientific merit and the priority score:

Protection of Human Subjects from Research Risk: The involvement of human subjects and protections from research risk relating to their participation in the proposed research will be assessed (see the Research Plan, Section E on Human Subjects in the PHS Form 398).

Inclusion of Women, Minorities and Children in Research: The adequacy of plans to include subjects from both genders, all racial and ethnic groups (and subgroups), and children as appropriate for the scientific goals of the research will be assessed. Plans for the recruitment and retention of subjects will also be evaluated (see the Research Plan, Section E on Human Subjects in the PHS Form 398).

Care and Use of Vertebrate Animals in Research: If vertebrate animals are to be used in the project, the five items described under Section F of the PHS Form 398 research grant application instructions will be assessed.

Biohazards: If materials or procedures are proposed that are potentially hazardous to research personnel and/or the environment, determine if the proposed protection is adequate.

2.B. Additional Review Considerations

Training in the Responsible Conduct of Research: Is the quality and appropriateness of the proposed training or instruction in areas related to the responsible conduct of research adequate?

Budget: Is the proposed budget and the requested period of support reasonable in relation to the proposed research and mentoring activities?

2.C. Sharing Research Data

A data sharing plan is not required.

2.D. Sharing Research Resources

NIH policy requires that grant awardee recipients make unique research resources readily available for research purposes to qualified individuals within the scientific community after publication (See the NIH Grants Policy Statement http://grants.nih.gov/grants/policy/nihgps/part_ii_5.htm#availofrr and http://www.ott.nih.gov/policy/rt_guide_final.html). Investigators responding to this funding opportunity should include a sharing research resources plan addressing how unique research resources will be shared or explain why sharing is not possible.

The adequacy of the resources sharing plan will be considered by Program staff of the funding organization when making recommendations about funding applications. Program staff may negotiate modifications of the resource sharing plan with the principal investigator before recommending funding of an application. The final version of the resource sharing plan negotiated by both will become a condition of the award of the grant. The effectiveness of the resource sharing will be evaluated as part of the administrative review of each non-competing Grant Progress Report (PHS 2590). See Section VI.3. Reporting.

3. Anticipated Announcement and Award Dates

Not applicable.

Section VI. Award Administration Information


1. Award Notices

After the peer review of the application is completed, the PD/PI will be able to access his or her Summary Statement (written critique) via the eRA Commons.

If the application is under consideration for funding, NIH will request "just-in-time" information from the applicant. For details, applicants may refer to the NIH Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards, Subpart A: General (http://grants.nih.gov/grants/policy/nihgps_2003/NIHGPS_part4.htm).

A formal notification in the form of a Notice of Award (NoA) will be provided to the applicant organization. The NoA signed by the grants management officer is the authorizing document. Once all administrative and programmatic issues have been resolved, the NoA will be generated via email notification from the awarding component to the grantee business official (designated in item 12 on the Application Face Page). If a grantee is not email enabled, a hard copy of the NoA will be mailed to the business official.

Selection of an application for award is not an authorization to begin performance. Any costs incurred before receipt of the NoA are at the recipient's risk. These costs may be reimbursed only to the extent considered allowable pre-award costs. See Also Section IV.5. Funding Restrictions.

2. Administrative and National Policy Requirements
 
All NIH grant and cooperative agreement awards include the NIH Grants Policy Statement as part of the NoA. For these terms of award, see the NIH Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards, Subpart A: General (http://grants.nih.gov/grants/policy/nihgps_2003/NIHGPS_Part4.htm) and Part II Terms and Conditions of NIH Grant Awards, Subpart B: Terms and Conditions for Specific Types of Grants, Grantees, and Activities (http://grants.nih.gov/grants/policy/nihgps_2003/NIHGPS_part9.htm).

The following related administrative policies apply to NIH Research Career Award (“K”) programs:

A. Evaluation

In carrying out its stewardship of human resource-related programs, the NIH may begin requesting information essential to an assessment of the effectiveness of this program.  Accordingly, recipients are hereby notified that they may be contacted after the completion of this award for periodic updates on various aspects of their employment history, publications, support from research grants or contracts, honors and awards, professional activities, and other information helpful in evaluating the impact of the program.

B. Other Income

Awardees may retain royalties and fees for activities such as scholarly writing, service on advisory groups, honoraria from other institutions for lectures or seminars, fees resulting from clinical practice, professional consultation or other comparable activities, provided these activities remain incidental, are not required by the research and research-related activities of this award, and provided that the retention of such pay is consistent with the policies and practices of the grantee institution.

All other income and fees, not included in the preceding paragraph as retainable, may not be retained by the career award recipient.  Such fees must be assigned to the grantee institution for disposition by any of the following methods:

Usually, funds budgeted in an NIH supported research grant for the salaries or fringe benefits of individuals, but freed as a result of a career award, may not be rebudgeted.  The awarding component will give consideration to approval for the use of released funds only under unusual circumstances.  Any proposed retention of funds released as a result of a career award must receive prior written approval of the NIH awarding component.

C. Special Leave

Leave to another institution, including a foreign laboratory, may be permitted if the proposed experience is directly related to the purpose of the award.  Only local institutional approval is required if such leave does not exceed 3 months.  For longer periods, prior written approval of the NIAAA or NIDA is required and will be granted only in unusual situations.  Details on the process for submission of prior approval requests can be founds in the NIH Grants Policy Statement, Requests for Prior Approval, at http://grants.nih.gov/grants/policy/nihgps_2003/NIHGPS_Part7.htm#_Toc54600130.)

The leave request must include the reasons for the leave and a description of the provisions that will be made to ensure that the awardee will be able to continue meeting the requirements of this award for research and mentoring activities during the period of the leave. A copy of a letter or other evidence from the institution where the leave is to be taken also must be submitted to assure that satisfactory arrangements have been made. If the request is approved, support from the K05 award will continue during such leave.

Leave for unusual and pressing circumstances will be considered on a case-by-case basis consistent with the policies of the NIH, NIAAA and NIDA. The nature of the circumstances requiring reduced effort might include medical conditions, disability, or pressing personal or family situations such as child or elder care.  Leave will not be approved to accommodate job opportunities, clinical practice, or clinical training.  In each situation, the grantee institution must submit documentation supporting the need for reduced effort along with assurance of a continuing commitment to the scientific development of the awardee. In all cases, leave without award support may not exceed 12 months. 

D. Changes in Research Activities or Mentoring Plans

Consultation with the applicable Institute program staff is required when a change in the research activities or a change in the mentoring plan being conducted under the K05 award is being considered.

Individual awards are made for career development at a specific institution to conduct specific research and mentoring activities.  A change in the specified scientific area of the research component or in the proposed mentoring activities of the career development program requires prior approval of the NIAAA or NIDA.  A scientific rationale must be provided for any proposed changes in the aims of the original peer-reviewed research plan.  Supporting justification for any significant changes to the proposed mentoring activities must also be provided. The new research plan or mentoring activities will be evaluated by Institute program staff to ensure that these components remain within the scope of the original peer-reviewed research program. For example, a change in research activities should not impair or prevent the conduct of the mentoring activities. The impact of the proposed changes to the research or mentoring plans on the mentored investigators will also be considered. If the proposed new activities are inconsistent with the goals and objectives of the K05 program, program staff could recommend that the award be terminated.

E. Change of Institution or Termination 

Consultation with the applicable Institute program staff is required when either a change of institution or termination is being considered. 

A change of grantee request normally will be permitted only when all of the benefits attributable to the original grant can be transferred. In reviewing a request to transfer a grant, NIAAA or NIDA will consider whether there is a continued need for the grant-supported project or activity and the impact of any proposed changes in the scope of the project.   A change may be made without peer review, provided the PI plans no significant change in research and mentoring objectives and the facilities and resources at the new organization will allow for successful performance of the project. If these conditions or other programmatic or administrative requirements are not met, the NIAAA or NIDA may require peer review or may disapprove the request and, if appropriate, terminate the award.

If the awardee is moving to another eligible institution, career award support may be continued provided:

When a grantee institution plans to terminate an award, the Grants Management Specialist listed on the NoA must be notified in writing at the earliest possible time so that appropriate instructions can be given for termination. Additionally, NIAAA or NIDA may terminate an award upon determination that the purpose or terms of the award are not being fulfilled.  In the event an award is terminated, NIAAA or NIDA shall notify the grantee institution in writing of this determination, the reasons therefore, the effective date, and the right to appeal the decision.

3. Reporting

Awardees will be required to submit the PHS Non-Competing Grant Progress Report, Form 2590, annually.  Note that the instructions for Research Career Development applications must be followed for this program.
http://grants.nih.gov/grants/funding/2590/2590.htm and financial statements as required in the NIH Grants Policy Statement.

The Progress Report must include Sections a through f as described on pages 10-14 in the general PHS form 2590 instructions, as well as sections g through j as described in Section IV of the 2590 instructions. Evaluation of the awardee’s progress will encompass the following:

A final progress report, invention statement, and Financial Status Report are required when an award is relinquished, when a recipient changes institutions, or when an award is terminated.

Section VII. Agency Contacts


We encourage your inquiries concerning this funding opportunity and welcome the opportunity to answer questions from potential applicants. Inquiries may fall into three areas: scientific/research, peer review, and financial or grants management issues:

1. Scientific/Research Contacts:

NIAAA

R. Thomas Gentry, Ph.D.
Division of Metabolism and Health Effects
National Institute on Alcohol Abuse and Alcoholism
5635 Fishers Lane, Room 2025, MSC 9304
Bethesda, MD 20892-9304
Telephone: 301-443-6009
FAX: 301-594-0673 
Email: tgentry@niaaa.nih.gov

NIDA

Mimi M. Ghim, Ph.D.
Office of Science Policy and Communications, NIDA
6001 Executive Blvd., Suite 5230,
MSC 9591
Bethesda, MD 20892
Telephone: (301) 443-6071
FAX: (301) 480-2485
E-mail: ghimm@mail.nih.gov

2. Peer Review Contacts:

NIAAA

Ernestine Vanderveen, Ph.D.
Director, Office of Extramural Activities
National Institute on Alcohol Abuse and Alcoholism
5635 Fishers Lane, Room 3039, MSC 9304
Bethesda, MD 20892-9304
Telephone: (301) 443-2531
FAX:  (301) 443-6099
Email: tvanderv@mail.nih.gov

NIDA

Teresa Levitin, Ph.D.
Director, Office of Extramural Affairs
National Institute on Drug Abuse/NIH/DHHS
6101 Executive Boulevard, Suite 220, MSC 8401
Bethesda, MD  20892-8401
Telephone:  (301) 443-2755
FAX:  (301) 443-0538
Email:  tlevitin@mail.nih.gov

3. Financial or Grants Management Contacts:

NIAAA

Judy Fox
Chief, Grants Management Branch
National Institute on Alcohol Abuse and Alcoholism
5635 Fishers Lane, Rm 3023, MSC 9304
Bethesda, MD  20892-9304
Telephone:  (301) 443-4704
FAX: (301) 443-3891
Email: jfox@mail.nih.gov

NIDA

Carol Alderson
Deputy Grants Management Officer
Grants Management Branch/OM
National Institute on Drug Abuse/NIH/DHHS
6101 Executive Boulevard
Suite 270
Bethesda, MD 20892-8403
Telephone: (301) 594-5614
FAX: (301) 594-6849
Email: ca10h@nih.gov

Section VIII. Other Information


Required Federal Citations

Use of Animals in Research:
Recipients of PHS support for activities involving live, vertebrate animals must comply with PHS Policy on Humane Care and Use of Laboratory Animals ( http://grants.nih.gov/grants/olaw/references/PHSPolicyLabAnimals.pdf), as mandated by the Health Research Extension Act of 1985 ( http://grants.nih.gov/grants/olaw/references/hrea1985.htm), and the USDA Animal Welfare Regulations   (http://www.nal.usda.gov/awic/legislat/usdaleg1.htm), as applicable.

Human Subjects Protection:
Federal regulations (45CFR46) require that applications and proposals involving human subjects must be evaluated with reference to the risks to the subjects, the adequacy of protection against these risks, the potential benefits of the research to the subjects and others, and the importance of the knowledge gained or to be gained. http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.htm.

Data and Safety Monitoring Plan:
Data and safety monitoring is required for all types of clinical trials, including physiologic toxicity, and dose-finding studies (phase I); efficacy studies (Phase II) efficacy, effectiveness and comparative trials (Phase III). Monitoring should be commensurate with risk. The establishment of data and safety monitoring boards (DSMBs) is required for multi-site clinical trials involving interventions that entail potential risks to the participants. (NIH Policy for Data and Safety Monitoring, NIH Guide for Grants and Contracts, June 12, 1998: http://grants.nih.gov/grants/guide/notice-files/not98-084.html).

Sharing Research Data:
Investigators submitting an NIH application seeking $500,000 or more in direct costs in any single year are expected to include a plan for data sharing or state why this is not possible. http://grants.nih.gov/grants/policy/data_sharing

Investigators should seek guidance from their institutions, on issues related to institutional policies, local IRB rules, as well as local, State and Federal laws and regulations, including the Privacy Rule. Reviewers will consider the data sharing plan but will not factor the plan into the determination of the scientific merit or the priority score.

Sharing of Model Organisms:
NIH is committed to support efforts that encourage sharing of important research resources including the sharing of model organisms for biomedical research (see http://grants1.nih.gov/grants/guide/notice-files/NOT-OD-04-042.html). At the same time the NIH recognizes the rights of grantees and contractors to elect and retain title to subject inventions developed with Federal funding pursuant to the Bayh Dole Act (see the NIH Grants Policy Statement http://grants.nih.gov/grants/policy/nihgps_2003/index.htm). All investigators submitting an NIH application or contract proposal beginning with the October 1, 2004 receipt date, are expected to include in the application/proposal a description of a specific plan for sharing and distributing unique model organism research resources generated using NIH funding or state why such sharing is restricted or not possible. This will permit other researchers to benefit from the resources developed with public funding. The inclusion of a model organism sharing plan is not subject to a cost threshold in any year and is expected to be included in all applications where the development of model organisms is anticipated.

Inclusion of Women And Minorities in Clinical Research:
It is the policy of the NIH that women and members of minority groups and their sub-populations must be included in all NIH-supported clinical research projects unless a clear and compelling justification is provided indicating that inclusion is inappropriate with respect to the health of the subjects or the purpose of the research. This policy results from the NIH Revitalization Act of 1993 (Section 492B of Public Law 103-43). All investigators proposing clinical research should read the "NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical Research (http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-001.html); a complete copy of the updated Guidelines is available at http://grants.nih.gov/grants/funding/women_min/guidelines_amended_10_2001.htm. The amended policy incorporates: the use of an NIH definition of clinical research; updated racial and ethnic categories in compliance with the new OMB standards; clarification of language governing NIH-defined Phase III clinical trials consistent with the new PHS Form 398; and updated roles and responsibilities of NIH staff and the extramural community. The policy continues to require for all NIH-defined Phase III clinical trials that: a) all applications or proposals and/or protocols must provide a description of plans to conduct analyses, as appropriate, to address differences by sex/gender and/or racial/ethnic groups, including subgroups if applicable; and b) investigators must report annual accrual and progress in conducting analyses, as appropriate, by sex/gender and/or racial/ethnic group differences.

Inclusion of Children as Participants in Clinical Research:
The NIH maintains a policy that children (i.e., individuals under the age of 21) must be included in all clinical research, conducted or supported by the NIH, unless there are scientific and ethical reasons not to include them.

All investigators proposing research involving human subjects should read the "NIH Policy and Guidelines" on the inclusion of children as participants in research involving human subjects that is available at http://grants.nih.gov/grants/funding/children/children.htm.

Required Education on The Protection of Human Subject Participants:
NIH policy requires education on the protection of human subject participants for all investigators submitting NIH applications for research involving human subjects and individuals designated as key personnel. The policy is available at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-039.html.

Human Embryonic Stem Cells (hESC):

Criteria for federal funding of research on hESCs can be found at http://grants.nih.gov/grants/stem_cells.htm and athttp://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-005.html.  Only research using hESC lines that are registered in the NIH Human Embryonic Stem Cell Registry will be eligible for Federal funding (see http://escr.nih.gov/). It is the responsibility of the applicant to provide the official NIH identifier(s) for the hESC line(s) to be used in the proposed research.  Applications that do not provide this information will be returned without review.

NIH Public Access Policy:

NIH-funded investigators are requested to submit to the NIH manuscript submission (NIHMS) system (http://www.nihms.nih.gov/) at PubMed Central (PMC) an electronic version of the author’s final manuscript upon acceptance for publication, resulting from research supported in whole or in part with direct costs from NIH.  The author’s final manuscript is defined as the final version accepted for journal publication, and includes all modifications from the publishing peer review process.

NIH is requesting that authors submit manuscripts resulting from 1) currently funded NIH research projects or 2) previously supported NIH research projects if they are accepted for publication on or after May 2, 2005.  The NIH Public Access Policy applies to all research grant and career development award mechanisms, cooperative agreements, contracts, Institutional and Individual Ruth L. Kirschstein National Research Service Awards, as well as NIH intramural research studies.  The Policy applies to peer-reviewed, original research publications that have been supported in whole or in part with direct costs from NIH, but it does not apply to book chapters, editorials, reviews, or conference proceedings.  Publications resulting from non-NIH supported research projects should not be submitted.

Additional information regarding the NIH Public Access Policy can be found at:  http://publicaccess.nih.gov/index.htm

Additional information regarding the submission process can be found in the Public Access Policy Author’s Manual found at: http://publicaccess.nih.gov/publicaccess_Manual.htm.

Access to Research Data through the Freedom of Information Act:

The Office of Management and Budget (OMB) Circular A-110 has been revised to provide access to research data through the Freedom of Information Act (FOIA) under some circumstances.  Data that are (1) first produced in a project that is supported in whole or in part with Federal funds and (2) cited publicly and officially by a Federal agency in support of an action that has the force and effect of law (i.e., a regulation) may be accessed through FOIA.  It is important for applicants to understand the basic scope of this amendment.  NIH has provided guidance at: http://grants.nih.gov/grants/policy/a110/a110_guidance_dec1999.htm.

Applicants may wish to place data collected under this PA in a public archive, which can provide protections for the data and manage the distribution for an indefinite period of time.  If so, the application should include a description of the archiving plan in the study design and include information about this in the budget justification section of the application. In addition, applicants should think about how to structure informed consent statements and other human subjects procedures given the potential for wider use of data collected under this award.

Standards for Privacy of Individually Identifiable Health Information:  

The Department of Health and Human Services (DHHS) issued final modification to the "Standards for Privacy of Individually Identifiable Health Information", the "Privacy Rule," on August 14, 2002.  The Privacy Rule is a federal regulation under the Health Insurance Portability and Accountability Act (HIPAA) of 1996 that governs the protection of individually identifiable health information, and is administered and enforced by the DHHS Office for Civil Rights (OCR). Those who must comply with the Privacy Rule (classified under the Rule as "covered entities") must do so by April 14, 2003 (with the exception of small health plans which have an extra year to comply).

Decisions about applicability and implementation of the Privacy Rule reside with the researcher and his/her institution. The OCR website (http://www.hhs.gov/ocr/) provides information on the Privacy Rule, including a complete Regulation Text and a set of decision tools on "Am I a covered entity?"  Information on the impact of the HIPAA Privacy Rule on NIH processes involving the review, funding, and progress monitoring of grants, cooperative agreements, and research contracts can be found at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-03-025.html.

URLs in NIH Grants Applications or Appendices:  

All applications and proposals for NIH funding must be self-contained within specified page limitations. For publications listed in the appendix and/or Progress report, internet addresses (URLs) must be used for publicly accessible on-line journal articles.  Unless otherwise specified in this solicitation, Internet addresses (URLs) should not be used to provide any other information necessary for the review because reviewers are under no obligation to view the Internet sites. Furthermore, we caution reviewers that their anonymity may be compromised when they directly access an Internet site.

Health People 2010:  

The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2010," a PHS-led national activity for setting priority areas. This PA is related to one or more of the priority areas. Potential applicants may obtain a copy of "Healthy People 2010" at http://www.health.gov/healthypeople.

Authority and Regulations:

This program is described in the Catalog of Federal Domestic Assistance No. 93.398 at http://www.cfda.gov/, and is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review.  Awards are made under authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241and 284) and administered under NIH grants policies described at http://grants.nih.gov/grants/policy/policy.htm and under Federal Regulations 42 CFR 52 and 45 CFR Parts 74 and 92.

 The PHS strongly encourages all grant recipients to provide a smoke-free workplace and discourage the use of all tobacco products.  In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care, or early childhood development services are provided to children.  This is consistent with the PHS mission to protect and advance the physical and mental health of the American people.

Loan Repayment Programs:  

Please note that NIH encourages applications for educational loan repayment from qualified health professionals who have made a commitment to pursue a research career involving clinical, pediatric, contraception, infertility, and health disparities related areas.  The Loan Repayment Program (LRP) is an important component of NIH’s efforts to recruit and retain the next generation of researchers by providing the means for developing a research career unfettered by the burden of student loan debt.  Note that an NIH grant is not required for eligibility and concurrent career award and LRP applications are encouraged.  The periods of career award and LRP award may overlap providing the LRP recipient with the required commitment of time and effort, because LRP awardees must commit at least 50% of their time (at least 20 hours per week based on a 40 hour week) for two years to research.  For further information, please see: http://www.lrp.nih.gov/


Weekly TOC for this Announcement
NIH Funding Opportunities and Notices


Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS)
  USA.gov - Government Made Easy


Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.