Release Date:  July 12, 1999


National Institute on Deafness and Other Communication Disorders

This NOTICE serves to announce new guidelines that supercede prior 
guidelines for NIDCD Program Project (P01) and Clinical Center (P50) 
Grants and represent a substantive change for these programs.

The National Institute on Deafness and Other Communication Disorders 
(NIDCD) multiple project center grants (P50) will be used to support 
interdependent, interrelated, and multidisciplinary approaches to 
behavioral and biomedical research on hearing, balance, smell, taste, 
voice, speech and language. Most research within the mission areas of 
the NIDCD can be best accomplished via the investigator-initiated 
individual research grant (R01), the research core center grant (P30)*, 
and the interactive research project grant (IRPG or interactive R01) 
mechanisms. There are special circumstances, in both basic and clinical 
research, however, that warrant the use of the P50 mechanism.

The essential criteria for Multiple Project Center Grant (P50) 
eligibility are listed below. All four of the criteria must be met for 
an application to be considered appropriate for the P50 mechanism.
1. The P50 must be multidisciplinary;
2. Each subproject must be interdependent AND interrelated with at least 
one other subproject;
3. The feasibility of the research proposed on any subproject would be 
significantly diminished if that subproject were submitted as a 
traditional individual research grant (R01) application; and,
4. Each P50 must have a well-defined central unifying theme consisting 
of three or more subprojects with supporting cores as appropriate.

Potential applicants for multiple project center grants (P50) are 
required to consult with NIDCD program staff and provide a written 
letter of intent before submission of an application. NIDCD will 
determine whether the planned project is, or is not, appropriate for the 
P50 mechanism. Only applications approved for submission will be 
accepted. Consultation with the NIDCD program staff is also required for 
renewal applications. Program staff are listed by program area at the 
end of this document under "STAFF CONSULTATION."


Applications will be accepted under these new guidelines beginning with 
the February 1, 2000 application receipt date. The receipt dates are the 
same for all new (Type 1), renewal (Type 2), and supplemental (Type 3) 
P50 applications.

Letter of Intent    Application     Initial     National        Earliest
Receipt Date        Receipt         Review      Advisory        Probable
                    Date            Group       Council         Start Date
August 1            February 1      June/July   Sept./Oct.      December 1
December 1          June 1          Oct./Nov.   Jan./Feb.       April 1
April 1             Oct. 1          Feb./March  May/June        July 1

Additional information may be obtained from NIDCD staff listed in this 
document or may be found at Applications (new, 
renewal, or revised) prepared using the old NIDCD Program Project (P01) 
and Clinical Center (P50) Grant Guidelines will be accepted only through 
the October 1, 1999 deadline. All applications for multiple project 
center grants (P50) received after October 1, 1999 must meet the new 


Inquiries about P50 applications should be directed to one of the NIDCD 
Program Administrators listed below. Consultation regarding competing 
continuation grant applications should be sought from the Program 
Administrator responsible for the existing P50/P01.

HEARING:       Drs. Donahue, Johnson, Luethke (email:;;
BALANCE:       Dr. Sklare (email:
SMELL/TASTE:   Dr. Small (email:
VOICE/SPEECH:  Dr. Ansel (email:
LANGUAGE:      Dr. Cooper (email:

*The Research Core Center (P30) also represents a new program/mechanism 
for the NIDCD. The P30 is an institutional award to support centralized 
resources and facilities shared by investigators with existing research 
projects. The overall goal of a Core Center is to promote cooperative 
interaction among basic science and/or clinical investigators in a 
manner that will enrich the effectiveness of ongoing research and 
promote new research directions. More information about the P30 can be 
found at http or from Dr. 
Donahue (

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

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Bethesda, Maryland 20892
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