REQUEST FOR COMPETING APPLICATIONS FROM THE NCI CLINICAL TRIALS COOPERATIVE
GROUPS TO CONDUCT CLINICAL STUDIES ON OLDER CANCER PATIENTS

Release Date:  October 22, 1998

P.T.

National Cancer Institute
National Institute on Aging

The Cancer Therapy Evaluation Program (CTEP), Division of Cancer Treatment and
Diagnosis (DCTD), National Cancer Institute (NCI) and the Geriatrics Program
(GP), National Institute on Aging (NIA) are soliciting competitive cooperative
agreement (U10) applications for up to five years of support from the adult
NCI Clinical Trials Cooperative Groups to conduct clinical studies that
promote the development of a knowledge base to produce new treatment
strategies for older patients (65 years and older). The paucity of data on
age-related issues and problems at the aging/cancer interface make it
difficult to provide definitive answers to many questions that arise about
cancer treatment in older persons. The goal of this research initiative is to
stimulate clinical trials research relevant to older persons with cancer.  The
risk of developing cancer increases with advancing age.  Investigators are
encouraged to develop information on the complexities of  treating patients
who are likely to have concomitant age-related conditions and other diseases
and how these clinical challenges can be resolved to improve the care and
treatment of older patients.  The necessary resources and infrastructure
consisting of access to patients and the existing tissue banks are in place
within the NCI Clinical Trials Cooperative Groups such that this initiative
will be able to capitalize and move research forward at a rapid pace.

NCI staff will contact the NCI Clinical Trials Cooperative Groups directly
regarding application procedures and format.

INQUIRIES

Written and telephone inquiries concerning this may be directed to:

Rosemary Yancik, Ph.D.
Geriatrics Program
National Institute on Aging
7201 Wisconsin Avenue, Suite 3E327 MSC 9205
Bethesda, MD  20892-9205
Telephone:  (301) 496-5278
FAX:  (301) 402-1784
Email:  ry3e@nih.gov

Richard Ungerleider, M.D.
Division of Cancer Treatment and Diagnosis
National Cancer Institute
6130 Executive Boulevard, Room 741
Bethesda, MD  20892-7436
Telephone:  (301) 496-2522
FAX:  (301) 403-0557
Email:  ru4m@nih.gov

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