Release Date:  August 14, 1998



National Institute of Allergy and Infectious Diseases

The Opportunistic Infections Research Branch, Therapeutics Research Program,
Division of AIDS, National Institute of Allergy and Infectious Diseases
(NIAID), NIH, has a requirement to develop therapies for the treatment of AIDS
and associated opportunistic infections.  The purpose of this Request for
Proposals (RFP) is to seek responsible offers for new tuberculosis drug
technology development and transfer support.  This contract is to serve as a
resource for facilitating the translation of anti-tuberculosis discoveries
into candidates for development and commercialization.


This contract will involve the use of information on compounds, which may be
confidential and proprietary.  All offerors except those deemed by the
Government to have an actual or apparent conflict of interest are eligible to
compete.  Organizations that are, or subsidiaries to, pharmaceutical or
chemical companies (i.e., an organization which sells drugs and/or chemicals
to the general public for profit) are examples of organizations that are
excluded from competition.  Documentation of commercial interests, such as
investors' prospectus or recent audit, must be supplied in an offeror's
business proposal.  The Government reserves the right to exclude any offeror. 
If there is ANY question about potential conflicts or APPARENT conflicts,
contact the Contracting Officer.

An Advance Understanding will be inserted in the resultant contract stating
that the NIAID shall be notified if the Contractor's conflict of interest
status has changed and that a determination shall be made regarding the
continuation of the contract.

It is anticipated that one cost reimbursement, completion type contract will
be awarded for a period of seven years, beginning approximately August 17,
1999.  RFP NIH-NIAID-DAIDS-99-17 is available electronically and may be
accessed through the NIAID Contract Management Branch (CMB) Home Page at the
following URL:

Please note that the RFP for this acquisition has been revised to include only
the Work Statement, Deliverable and Reporting Requirements, Special
Requirements and Mandatory Qualification, if any, the Technical Evaluation
Criteria, and the Proposal Preparation Instructions.  All information required
for the submission of an offer will be contained in the electronic RFP
package.  Following proposal submission and the initial review process,
offerors comprising the competitive range will be requested to provide
additional documentation to the Contracting Officer.

Responses to this RFP will be due on November 13, 1998.  Any  responsible
offeror may submit a proposal which will be considered by the Government. 
This advertisement does not commit the Government to award a contract.


For further information contact:

Joyce U. Sagami
Contracts Management Branch
National Institute of Allergy and Infectious Diseases
6003 Executive Boulevard, Room 3C07, MSC 7610
Bethesda, MD  20892-7610
Telephone:  (301) 496-7118
FAX:  (301) 402-0972

No collect calls will be accepted.

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