FINDINGS OF SCIENTIFIC MISCONDUCT NIH GUIDE, Volume 26, Number 12, April 11, 1997 P.T. 34 Keywords: Ethics/Values in Science & Technol Grants Administration/Policy+ Department of Health and Human Services Notice is hereby given that the Office of Research Integrity (ORI) has made a final finding of scientific misconduct in the following case: Enrico Portuese, University of Pittsburgh: Based upon an investigation conducted by the University of Pittsburgh, information obtained by the Office of Research Integrity (ORI) during its oversight review, and Mr. Portuese~s own admission, ORI found that Mr. Portuese, a former graduate student in the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, engaged in scientific misconduct by fabricating research data in biomedical research supported by two grants from the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), National Institutes of Health (NIH). Specifically, Mr. Portuese fabricated data in a study of angiotensin-converting enzyme polymorphism and complications from insulin-dependent diabetes mellitus. These fabricated data were included in an abstract that was submitted to the American Diabetes Association in January 1996; however, the abstract was not accepted, presented in public, or published. In addition, Mr. Portuese fabricated genetic data on lipoprotein lipase polymorphisms as related to diabetes complications and risk factors. These fabricated data were included in tables prepared by Mr. Portuese and presented by him to his doctoral committee in October 1996. None of the fabricated data in question has been published, presented at a scientific meeting, or used in any grant applications. Mr. Portuese has accepted the ORI finding and has entered into a Voluntary Exclusion Agreement with ORI in which he has voluntarily agreed, for the three year period beginning March 25, 1997: (1) to exclude himself from serving in any advisory capacity to the Public Health Service (PHS), including but not limited to service on any PHS advisory committee, board, and/or peer review committee, or as a consultant; and (2) that any institution that submits an application for PHS support for a research project on which Mr. Portuese~s participation is proposed or which uses him in any capacity on PHS supported research must concurrently submit a plan for supervision of his duties. The supervisory plan must be designed to ensure the scientific integrity of Mr. Portuese~s research contribution. The institution must submit a copy of the supervisory plan to ORI. No scientific publications were required to be corrected as part of this Agreement. INQUIRIES For further information contact: Acting Director, Division of Research Investigations Office of Research Integrity 5515 Security Lane, Suite 700 Rockville, MD 20852 Telephone: (301) 443-5330 .
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