NIH Guide, Volume 26, Number 8, March 14, 1997


RFA:  HL-97-002


P.T. 34


  Monoclonal Antibodies 




National Heart, Lung, and Blood Institute


Letter of Intent Receipt Date:  March 17, 1997

Application Receipt Date:  April 18, 1997




This notice is an addendum to Request for Applications (RFA)

HL-97-002, Human Anti-HIV Monoclonal Antibodies in Immunotherapy of

HIV, which was published in the NIH Guide for Grants and Contracts,

Vol. 25, No. 43, December 13, 1996.  The purpose of this addendum is

to inform potential applicants of an administrative modification

regarding the "Mechanism of Support" described on page two of the

RFA.  In accordance with the specific application instructions, the

MODULAR GRANT concept must be followed by applicants.  As specified

in the RFA, funds must be requested in $25,000 direct cost modules.

However, instead of a maximum of eight modules per year ($200,000

total direct costs), the NHLBI has increased this number to a maximum

of twelve modules ($300,000 total direct costs) in order to

accommodate more costly research studies such as, but not limited to,

primates. The number of modules (total direct costs), at any level,

requested in the application must be fully justified.




Inquiries concerning this announcement are encouraged.  The

opportunity to clarify any issue or questions from potential

applicants are welcome. Potential applicants may request a copy of

sample budge pages.  For programmatic issues, contact:


Dr. Luiz H. Barbosa

Division of Blood Diseases and Resources

National Heart, Lung, and Blood Institute

6701 Rockledge Drive, MSC 7950

Bethesda, MD  20892-7950

Telephone:  (301) 435-0075

FAX:  (301) 480-0868



For fiscal matters, contact:


Ms. Jane R. Davis

Division of Extramural Affairs

National Heart, Lung, and Blood Institute

6701 Rockledge Drive, MSC 7926

Bethesda, MD  20892-7926

Telephone:  (301) 435-0166

FAX:  (301) 480-3310




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