COOPERATIVE FAMILY REGISTRY FOR EPIDEMIOLOGIC STUDIES OF COLON CANCER- ADDENDUM NIH GUIDE, Volume 25, Number 25, July 26, 1996 P.T. 34 Keywords: Cancer/Carcinogenesis Epidemiology Registries+ National Cancer Institute The following information was inadvertently omitted from the SPECIAL REQUIREMENTS section immediately preceding the section on Terms and Conditions of Award in RFA CA-96-011, "Cooperative Family Registry for Epidemiologic Studies of Colon Cancer," published in the NIH Guide, Volume 25, Number 21, June 28, 1996: DEFINITIONS AWARDEE: The organization to which a cooperative agreement is awarded and which is responsible and accountable to NCI for the use of funds provided and for performance of the project supported by the cooperative agreement. PRINCIPAL INVESTIGATOR (PI): The single individual at the Awardee's Institution designated by the Awardee in the cooperative agreement application, who is responsible for the scientific and technical direction of the project. OPERATION CORE (OP): The central site at the Applicant/Awardee Institution that handles the coordination and storage of epidemiological and pedigree data and the biological specimen repository. All the data and specimens from each Applicant/Awardee Institution will be coordinated and located at one central location within the Awardee's own Institution. The PI serves as the head of the Coordination Site. NCI PROGRAM COORDINATOR: The Extramural Programs Branch (EPB) Program Director and who will be interacting scientifically and administratively with the Applicant/Awardee Institutions and providing guidance of the overall program for NCI. STEERING COMMITTEE (SC): A committee whose membership includes the NCI Program Coordinator, the PI and one other investigator from each awarded cooperative agreement, and one research scientist with expertise in translational colorectal cancer research who is not affiliated with any of the Awardee Institutions. This research scientist on the SC will be appointed by mutual agreement of the NCI Program Coordinator and the PIs. The SC will serve as the governing board of the CFRCCS. (For further information on the SC functions, see 3.a. under Terms and Conditions of Award.) ADVISORY COMMITTEE (AC): A committee composed of senior scientists with experience in multidisciplinary and translational colorectal cancer research and the NCI Program Coordinator. The members of the panel will evaluate all research proposals (those of the awardees as well as proposals from the research community at-large) proposing to utilize the CFRCCS's resources according to the evaluation and the review criteria provided by the SC. The AC will provide a recommendation to the SC regarding the priority of the proposed research. The membership of the AC may vary, as "ad hoc" members may be selected by the SC if additional expertise is needed for specific proposals to be reviewed. All permanent AC members will be selected by the SC (two nominees per awarded site), and their tenure will be for two years. (For further information on the AC functions, see 3.b. under Terms and Conditions of Award.) All other aspects of the RFA remain the same. INQUIRIES Direct inquiries regarding programmatic issues to: Dr. Daniela Seminara Extramural Programs Branch National Cancer Institute Executive Plaza North, Suite 535 6130 Executive Boulevard MSC 7395 Bethesda, MD 20892-7395 Telephone: (301) 496-9600 Email: [email protected] .
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