NIH GUIDE, Volume 25, Number 10, March 29, 1996




P.T. 34



  Neural Stimulation 


National Institute of Neurological Disorders and Stroke


The Neural Prosthesis Program (NPP) of the National Institute of

Neurological Disorders and Stroke (NINDS) develops implanted devices

that interface directly with the nervous system to replace or

supplement function in neurologically disabled individuals.  This

includes visual prostheses for blind individuals based on electrical

stimulation of the visual processing portions of the brain.  A

transcutaneous stimulation system consisting of an extracorporeal

computer controlled transmitter and a group of implantable

receiver-stimulator modules, each with 256 stimulus channel outputs,

is needed.  Research and development are required to assure that the

implanted portion of this system will be small enough to fit safely

and comfortably beneath the scalp and that the stimulus outputs are

flexible enough to provide the range of stimulus parameters necessary

for producing appropriate sensations of light by intracortical

microstimulation.  This transcutaneous transmission system will

interface not only with discrete wire microelectrodes but also with

silicon microstimulating microelectrodes presently being developed by

other investigators in the NPP.  The extracorporeal portion of the

system will include a computer controlled transmitter for sending

power and control signals across the skin to the implanted

receiver-stimulator modules.  Independently, and not as an agent of

the government, the contractor shall exert its best efforts to design

and fabricate a transcutaneous transmission system suitable for use

in a human visual prosthesis.  The contractor will not be required to

furnish the microelectrodes nor perform any animal or human testing.

Performance of this research project will require expertise in

monolithic semiconductor circuit design, high density interconnects

and implant packaging.  It is anticipated that one award, on a

cost-reimbursement basis, will be made for a period of three years.




This is not a Request for Proposals (RFP).  RFP No. NIH-NINDS-96-08

will be issued on or about March 25, 1996 with responses due

approximately 60 days thereafter.  Interested organizations should

request either a streamlined version or the entire RFP document.  If

no selection is made, a streamlined version of the RFP will be

provided.  The streamlined version includes only the Statement of

Work, deliverable and reporting requirements, special requirements,

and technical evaluation criteria.  After examination of these

documents, any organization interested in responding to the RFP must

request the entire RFP either in writing or by FAX.  Requests must

cite the RFP number and supply this office with two self-addressed

mailing labels.  All responsible sources may submit a proposal that

will be considered by the Government.


Contracts Management Branch, DEA

National Institute of Neurological Disorders and Stroke

7550 Wisconsin Avenue, , Room 910 - MSC 9190

Bethesda, MD  20892-9190


FAX:  (301) 402-4225



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