NIH GUIDE, Volume 25, Number 4, February 16, 1996




P.T. 34


  Rheumatic Diseases 

  Skin Diseases 

  Gene Therapy+ 


National Institute of Arthritis and Musculoskeletal and Skin Diseases


The National Institute of Arthritis and Musculoskeletal and Skin

Diseases (NIAMS) is seeking proposals for developmental and applied

research of gene therapy for skin and rheumatic diseases.  The scope

of the research includes improvement and adaptation of current gene

therapy technology, development of new methods to introduce, maintain

and regulate gene expression in target organs and cells, production

of new reagents for gene therapy, and development of innovative

experimental systems to test the feasibility of using gene therapy

technologies for the treatment of human skin and rheumatic diseases.

The offeror will select the disease to be investigated and will

justify the selection as being ready for gene therapy research

efforts.  The Government anticipates awarding three to four cost-

reimbursement contracts as a result of this solicitation.  BAA NIH-

NIAMS-96-1 will be available on or about March 1, 1996 and proposals

will be due on or about May 1, 1996.




Interested organizations should request either a streamlined or full

BAA package.  If no selection is made, a streamlined version of the

BAA will be provided, which includes only the Research and Technical

Objectives, reporting requirements, special requirements, mandatory

qualifications, if any, and technical evaluation criteria.  After

examination of these documents, any organization interested in

responding to this BAA must request the entire BAA package in

writing.  Faxed requests will also be accepted.  Requests will be

filled on a first-come, first-served basis, until the supply is

exhausted.  This advertisement does not commit the Government to

award a contract.  Written requests may be submitted to the following



Eileen Webster-Cissel

Contracts Management Branch

National Institute of Arthritis and Musculoskeletal and Skin Diseases

45 Center Drive, Room 5AS13A - MSC 6500

Bethesda, MD  20892-6500

Telephone:  (301) 594-2543

FAX:  (301) 480-4543



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