NIH GUIDE, Volume 24, Number 41, December 1, 1995


P.T. 34




National Institute of Neurological Disorders and Stroke

The Neural Prosthesis Program of the National Institute of

Neurological Disorders and Stroke (NINDS), National Institutes of

Health (NIH), supports research and development on functional

neuromuscular stimulation (FNS) to restore hand and arm function in

quadriplegic individuals.  These FNS systems must operate under the

voluntary control of the individual.  Providing a means for the

individual to produce the control signals represents a critical part

of any potential FNS system.  Presently, control signals are

generated by voluntary movements of unparalyzed muscles such as the

contralateral shoulder.

This project will investigate the ability of cortical cells in a

neurologically intact animal to control an artificial output device

on a chronic basis.  The goal of this work is to establish the

feasibility of generating control signals through voluntary control

of neurons in the central nervous system (CNS).  To demonstrate

cortical control, it is necessary to show that the neural activity in

selected cell populations in the CNS can be trained to reliably

control an electromechanical device.  It is anticipated that one

award, on a cost-reimbursement basis, will be made for a period of

three years.


This is not a Request for Proposals.  Request for Proposals (RFP) No.

NIH-NINDS-96-02 will be issued on or about November 20, 1995, with

responses due on or about January 22, 1996.  Interested organizations

may request either a streamlined version or an entire RFP document.

If no selection is made, a streamlined version of the RFP will be

provided.  The streamlined version includes only the Statement of

Work, deliverable and reporting requirements, special requirements,

and technical evaluation criteria.  After examination of these

documents, any organization interested in responding to the RFP must

request the entire RFP either in writing or by FAX request.  Requests

must cite the RFP number referenced above.  Supply this office with

two self-addressed mailing labels.  All responsible sources may

submit a proposal that will be considered by the Government.

Laurie Leonard


Contracts Management Branch, DEA

National Institute of Neurological Disorders and Stroke

7550 Wisconsin Avenue, Room 901 - MSC 9190

Bethesda, MD  20892

FAX:  (301) 402-4225


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