NIH GUIDE, Volume 24, Number 1, January 13, 1995


P.T. 34


  Dental Health & Hygiene 

National Institute of Dental Research

The National Institute of Dental Research (NIDR) has a requirement

for the development and implementation of a cross-sectional

evaluation of the exposure to fluorides of adolescents living in

nonfluoridated or fluoridated communities and the dental caries and

fluorosis status of these individuals.  The general objectives of the

study are:  to quantify fluoride exposure of individuals in both

fluoridated and nonfluoridated communities; to establish individual

variation and response to fluoride exposure by estimating fluoride

distribution in body fluids and tissues, as well as disease and

tissue expression (dental caries and fluorosis); to correlate the

fluoride levels from different body fluids and tissues with each

other and with reported current intake, past fluoride experience

presenting as dental fluorosis, and dental caries experience; and to

contrast these relationships in fluoridated and nonfluoridated

communities and between groups of individuals with different

fluorosis manifestations.


RFP No. NIH-NIDR-1-95-4R will be available approximately February 3,

1995, with proposals due on or about March 17, 1995.  Requests for

the RFP must be submitted in writing, addressed to:

Ms. Marion L. Blevins

Contract Management Section

National Institute of Dental Research

Natcher Building, Room 4AN-44D

Bethesda, MD  20892


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