NIH GUIDE, Volume 23, Number 45, December 23, 1994


P.T. 34



  Physiology, Human 


National Institute on Aging

The National Institute on Aging (NIA) will support through a research

contract, an epidemiologic study, Dynamics of Health, Aging and Body

Composition (HEALTH ABC).  The primary objective of the study is to

examine the incidence of physical disability in relation to body

composition and weight-related health conditions in healthier older

persons.  Change in body composition in old age, particularly loss of

muscle mass and bone, may be a common pathway by which several

diseases contribute to risk of disability.  The reasons for changes

in weight and body composition in old age and the influence of these

changes on health outcomes are not fully understood.  The HEALTH ABC

will include a total of 3,000 noninstitutionalized white and African-

American men and women aged 70-79.  Incident change in physical

function and related disability are the major outcomes.  Serial

measurement of body composition using dual energy x-ray

absorptiometry will be accompanied by measures of anthropometry,

strength, fitness, and physical function.  A key component of the

study is the assessment by objective measures of weight-related

health conditions including osteoarthritis, cardiovascular disease,

osteoporosis, pulmonary disease, diabetes, selected cancers, and

depression.  An eight-year cost-reimbursement type contract is

anticipated.  Two awards are expected.  The solicitation is scheduled

to be issued on or about December 28, 1994.  Proposals will be due 90

days after the date of issuance of the solicitation.  All responsible

sources may submit a proposal that will be considered by the



Copies of the solicitation may be obtained by sending a written

request to:

Donna Winters

Division of Contracts and Grants

National Institutes of Health

6100 Executive Boulevard, Room 6E01 (MSC 7540)

Bethesda, MD  20892-7540

Telephone:  (301) 496-4487


Return to 1994 Index

Return to NIH Guide Main Index

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS)
  USA.gov - Government Made Easy

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.