DYNAMICS OF HEALTH, AGING AND BODY COMPOSITION - FIELD CENTER NIH GUIDE, Volume 23, Number 45, December 23, 1994 RFP AVAILABLE: NIH-AG-95-04 P.T. 34 Keywords: Epidemiology Physiology, Human Aging/Gerontology National Institute on Aging The National Institute on Aging (NIA) will support through a research contract, an epidemiologic study, Dynamics of Health, Aging and Body Composition (HEALTH ABC). The primary objective of the study is to examine the incidence of physical disability in relation to body composition and weight-related health conditions in healthier older persons. Change in body composition in old age, particularly loss of muscle mass and bone, may be a common pathway by which several diseases contribute to risk of disability. The reasons for changes in weight and body composition in old age and the influence of these changes on health outcomes are not fully understood. The HEALTH ABC will include a total of 3,000 noninstitutionalized white and African- American men and women aged 70-79. Incident change in physical function and related disability are the major outcomes. Serial measurement of body composition using dual energy x-ray absorptiometry will be accompanied by measures of anthropometry, strength, fitness, and physical function. A key component of the study is the assessment by objective measures of weight-related health conditions including osteoarthritis, cardiovascular disease, osteoporosis, pulmonary disease, diabetes, selected cancers, and depression. An eight-year cost-reimbursement type contract is anticipated. Two awards are expected. The solicitation is scheduled to be issued on or about December 28, 1994. Proposals will be due 90 days after the date of issuance of the solicitation. All responsible sources may submit a proposal that will be considered by the Government. INQUIRIES Copies of the solicitation may be obtained by sending a written request to: Donna Winters Division of Contracts and Grants National Institutes of Health 6100 Executive Boulevard, Room 6E01 (MSC 7540) Bethesda, MD 20892-7540 Telephone: (301) 496-4487 .
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