NIH GUIDE, Volume 23, Number 11, March 18, 1994


P.T. 34, II


  Cardiovascular Diseases 

  Diagnosis, Medical 

National Heart, Lung, and Blood Institute

The National Heart, Lung, and Blood Institute (NHLBI) requires three

to five clinical centers to evaluate innovative diagnostic methods

that will improve the diagnostic reliability of cardiovascular

testing in evaluation of ischemic heart disease in women.  Innovative

approaches proposed in evaluation of myocardial ischemia should

include physiologic or functional measurements such as impaired

metabolism, perfusion, or endothelial function as well as assessment

of epicardial coronary arteries by angiography.  Each clinical center

will be fully independent and expected to fulfill all the

requirements outlined in the Request for Proposals (RFP).  The

clinical centers will evaluate diagnostic methods and perform common

study protocols, including angiography, on 100 participants annually

for three years.  The anticipated period of performance is from

December 30, 1994 through December 29, 1998.


This is an announcement for an RFP.  RFP No. NHLBI-HC-94-13 will be

available on or about March 14, 1994 with proposals due May 31, 1994.

Three to five awards are anticipated to be made in December 1994.

Written requests must cite RFP No. NHLBI-HC-94-13 and include two,

self-addressed mailing labels.

Requests for copies of the RFP are to be sent to:

Donna J. Neal

Contracts Operations Branch

National Heart, Lung, and Blood Institute

Federal Building, Room 3C16

7550 Wisconsin Avenue

Bethesda, MD  20892


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