ANIMAL MODEL TESTING OF TUBERCULOSIS DRUGS NIH GUIDE, Volume 22, Number 33, September 17, 1993 RFP AVAILABLE: NIAID-DAIDS-94-25 P.T. Keywords: National Institute of Allergy and Infectious Diseases The Developmental Therapeutics Branch, Basic Research and Development Program, Division of AIDS, National Institute of Allergy and Infectious Diseases (NIAID), has a requirement for animal model testing of potential therapies against Tuberculosis (TB). The Contractor will be required to: test potential therapeutic agents for efficacy in a mouse model and provide relevant strains of TB to do so; demonstrate the ability to modify or improve the proposed model and design alternative protocols; perform additional studies such as efficacy in models or acute infection measuring mortality as the endpoint, comparison of different strains of TB in efficacy evaluations, determinations of optimal dosages, routes, and schedules of administration. Offerors must have a Bio-Safety Level 3 animal facility at time of award to be considered. Therapeutic agents to be evaluated will be supplied by the Government, through a contract to be awarded for the acquisition of compounds for TB research. This announcement is for a new solicitation and it anticipated that there will be one award made. The issuance of the Request for Proposals (RFP) will be on or about September 17, 1993, with proposals due by COB on or about December 17, 1993. A five-year, cost-reimbursement contract is anticipated. INQUIRIES Requests for the RFA may be directed to: Mr. Bruce E. Anderson Contract Management Branch National Institute of Allergy and Infectious Diseases Solar Building, Room 3C07 6003 Executive Boulevard Bethesda, MD 20892 Telephone: (301) 496-8371 FAX: (301) 402-0972 A short-form version of the RFA will be available, for informational purposes, which includes only the background information, the full Statement of Work, and Evaluation Criteria. There is sufficient information in this document to enable prospective offerors to determine if they have the expertise/capability to meet the Government's requirements. A full-text version will also be available, which includes all the necessary information, business forms, etc., in order to submit a proposal. There are a limited number of full-text versions available. Therefore, request the short-form RFP first, then the full-text version only if you are going to submit a proposal. All request must be in writing. Specify whether you are requesting the short version or full-text version of the RFP. FAX requests are acceptable, but it is preferred that requests be made in writing and two self-addressed mailing labels be provided. .
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