HUMAN TISSUE AVAILABLE FOR RESEARCH INTO DEVELOPMENTAL DISORDERS

NIH GUIDE, Volume 22, Number 31, August 27, 1993



P.T. 34



Keywords:

  Tissue Culture 

  Biological Resources 



National Institute of Child Health and Human Development



The National Institute of Child Health and Human Development (NICHD)

has contracted for the collection of tissues to further research into

human developmental disorders such as chromosomal disorders,

encephalopathies, aminoacidopathies, leukodystrophies, lysosomal

disorders, neurological disorders, sudden infant death syndrome

(SIDS), unexplained mental retardation, and autism.



Currently tissue is available for distribution from over 140 cases

including SIDS infants, chromosomal disorders (primarily fetal

tissue), non-affected cases, accidental deaths, deaths from known

causes (primarily infection and congenital abnormalities),

anencephaly, depression, hydrocephalus, seizure disorders, spina

bifida, etc.



Tissues are stored at -85 degrees Celsius or fixed in 20 percent

formalin.  Tissues collected include cerebral coronal hemisections,

medulla, brainstem, cerebellum, dura, cranial and peripheral nerves,

CSF, vitreous humor, whole blood, and various tissues from the

cardiovascular, endocrine, gastrointestinal, genital, hematopoietic

system, integumentary, musculoskeletal, respiratory, and urinary

systems.  The contract also provides for a collaboration with

investigators who have access to tissue from patients with the above

disorders.  This collaboration may include recovery of tissue,

storage, publicizing the availability of tissue, and the distribution

of tissues to qualified investigators.



INQUIRIES



Direct inquiries regarding this research resource to:



Felix de la Cruz, M.D.

Center for Research for Mothers and Children

National Institute of Child Health and Human Development

6100 Building, Room 4B09

Bethesda, MD  20892

Telephone:  (301) 496-1383



Marian Willinger, Ph.D.

Center for Research for Mothers and Children

National Institute of Child Health and Human Development

6100 Building, Room 4B03

Bethesda, MD  20892

Telephone:  (301) 496-5575



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