IN UTERO STEM CELL TRANSPLANTATION FOR GENETIC DISEASES NIH GUIDE, Volume 22, Number 30, August 20, 1993 RFA: HL-93-014 P.T. 34 Keywords: Blood Diseases Transplantation of Organs Disease Model Genetics Metabolic Diseases National Heart, Lung and Blood Institute National Institute of Diabetes and Digestive and Kidney Diseases Letter of Intent Receipt Date: October 1, 1993 Application Receipt Date: November 17, 1993 The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) will join with the National, Heart, Lung and Blood Institute (NHLBI) to co-sponsor the Request for Applications (RFA) HL-93-014 entitled "In Utero Stem Cell Transplantation for Genetic Disease," published in the NIH Guide for Grants and Contracts, Vol. 22, No. 14, April 9, 1993. The NIDDK has a continuing interest in the support of research on the development of in utero stem cell transplantation for the treatment of genetic metabolic diseases with particular emphasis on lysosomal storage diseases and mucopolysaccharidoses. Since these metabolic diseases have been shown to be ameliorated by postnatal bone marrow transplants, they would make appropriate model systems for the development of in utero stem cell transplantation. Applications received in response to this RFA that propose to treat genetic metabolic diseases will be considered for funding by both the NHLBI and the NIDDK. Interested investigators are encouraged to contact Program Staff to discuss potential applications and to obtain the full text of the amended RFA. Inquiries may be addressed to: Dr. Catherine McKeon Division of Diabetes, Endocrinology and Metabolic Diseases National Institute of Diabetes and Digestive and Kidney Diseases Westwood Building, Room 621 Bethesda, MD 20892 Telephone: (301) 594-7582 FAX: (301) 594-9011 .
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