IN VITRO BIOGENIC AMINE TRANSPORTER TESTING FOR POTENTIAL COCAINETREATMENT MEDICATIONS



NIH GUIDE, Volume 22, Number 10, March 12, 1993



RFP AVAILABLE:  NO1DA-3-8303



P.T. 34



Keywords:

  Drugs/Drug Abuse 

  Screening of Drugs/Agents 



National Institute on Drug Abuse



The National Institute on Drug Abuse (NIDA) is soliciting proposals

from qualified organizations having in-house capacity to perform in

vitro biogenic amine transporter assays to systematically define

biochemical activities of compounds at these targets.  These assays

will be utilized to evaluate these compounds for potential use as

cocaine abuse treatment agents.  The ability of these compounds to

bind to the biogenic amine transporters and affect uptake and release

at these sites will be investigated.  The offeror must also indicate

possession of current DEA registration for Schedule II-V substances

prior to award and apply for Schedule I registration, if necessary.

It is estimated that a three and one-half year contract, that will

include options for additional compound screens and profiles, will

result from this procurement.



Estimated issuance date of RFP No. NO1DA-3-8303 is March 16, 1993 and

responses are due to be received in the Contracting Office 45

calendar days thereafter.  Written requests for copies of the

solicitation will be honored if received within twenty calendar days

after issuance of the solicitation.  Written requests received after

this period will be filled on a first come, first served basis until

the supply is exhausted; however, there is no assurance that copies

requested after the twentieth day will reach the requester before the

due date for receipt of responses.



INQUIRIES



Written requests are to be forwarded to:



Contract Specialist

National Institute on Drug Abuse

Parklawn Building, Room 10-49

5600 Fishers Lane

Rockville, MD  20857



.

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