NIH GUIDE, Vol, 21, No. 21, June 5, 1992

P.T. 34


  Biological Resources 

  Cell Lines 

National Center for Research Resources

The National Cell Culture Center is a resource facility that provides

large-scale mammalian cell culture services.  The Center, available to

researchers throughout the United States, has been established to

alleviate the current shortage of facilities and expertise required to

meet the cell culture needs of the biomedical research community.

Specifically, the Cell Culture Center supports basic research by

providing investigators with the following customized services:

o Large quantity production of mammalian cells in suspension or

monolayer cultures.  Quantities range from 10 to 150 liters.

o Large quantity production of monoclonal antibodies.  Quantities range

from 0.5 to 100 grams.

o Large quantity production of non-hybridoma cell secreted proteins.

Quantities vary depending on individual cell lines.

An application form, obtained from the Cell Culture Center, must

contain a description of the relevant research project. Following

approval of the application by the Cell Culture Center's Scientific

Advisory Board, the applicant's cell line is sent to the Center, and

grown to the requested amount. Researchers are charged only for the

consumable materials and a portion of the labor costs required for each


The Cell Culture Center is supported by a cooperative agreement award

from the National Center for Research Resources, NIH.


Programmatic inquiries regarding this research resource are encouraged

and are to be directed to:

Biological Models and Materials Research Program

National Center for Research Resources

Westwood Building Room 8A07

5333 Westbard Avenue

Bethesda, MD  20892

Telephone:  (301) 496-9840

Application forms may be requested from:

Director, National Cell Culture Center

8500 Evergreen Boulevard

Minneapolis, MN  55433

Telephone:  1-800-325-1112


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