A PROSPECTIVE COHORT STUDY OF CANCER AMONG MEN AND WOMEN INAGRICULTURE (FIELD STATIONS) NIH GUIDE, Volume 21, Number 14, April 10, 1992 RFP AVAILABLE: NCI-CP-21096-21 P.T. 34 Keywords: Cancer/Carcinogenesis Epidemiology Etiology National Cancer Institute PLEASE NOTE: This announcement has been published in the Commerce Business Daily. Because of the late date of this announcement in the Guide, it is published for information purposes only. The National Cancer Institute (NCI) is seeking contractors to perform the above named project. The contracts will create a field station(s) for epidemiologic studies in states that produce grain and livestock and/or in states with a significant proportion of minority farmers that produce other nonperishable commodities. It is anticipated that at least two field stations will be necessary to create a large cohort (approximately 156,000 persons) that can be followed prospectively for 10 years or more to obtain detailed information on agricultural exposures, diet, cooking practices, and other factors of etiologic interest for the study of cancer and other diseases. The field station(s) shall be located in a state(s) with population-based cancer registries and pesticide applicator registries with at least 20,000 registrants. It is desirable, but not mandatory, for the state to also have a birth defects registry. The study is designed to investigate biomarkers of exposure and disease. The entire cohort will include farm owner/operators (70,000), their spouses (56,000), or commercial and noncommercial applicators (30,000). The cohort will be assembled by enrolling applicators as they come to obtain or renew a pesticide application license at the Agricultural Extension Service Offices. The spouses of farm applicators will be invited to enroll in the cohort when their spouse is enrolled. It is anticipated that it will take three to four years to assemble the entire cohort since licenses are renewed on a three-four year cycle in many states. The NCI expects to award three cost-reimbursement, completion type contracts for a 60-month period. The Request for Proposals (RFP) was available on March 23, 1992 and proposals are due by April 27, 1992. Awards are anticipated by September 30, 1992. All responsible sources meeting the criteria are encouraged to submit an offer and will be considered by the NCI. No collect calls will be accepted. Copies of the RFP may be obtained by submitting a written request to: Barbara A. Shadrick, Contract Specialist Research Contracts Branch, OD Cancer Etiology Contracts Section National Cancer Institute Executive Plaza South, Suite 620 Bethesda, MD 20892 Telephone: (301) 496-8611 .
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