RAPID ACCESS TO PREVENTIVE INTERVENTION DEVELOPMENT RAPID - ADDENDUM Release Date: June 20, 2001 NOTICE: NOT-CA-01-014 National Cancer Institute Investigators are hereby notified that the receipt date for requests for RAPID resources has been changed to October 1, 2001. Investigators are further notified that the contact person and web site for the RAPID program have changed, see http://cancer.gov/rapid. The Rapid Access to Preventive Intervention Development (RAPID) program makes available to academic investigators the preclinical and early clinical drug development contract resources of NCI’s Division of Cancer Prevention. The goal of the RAPID program is the expeditious movement of novel molecules and concepts from the laboratory to the clinic for clinical trials of efficacy. RAPID will assist investigators who submit successful requests by providing any (or all) of the preclinical and phase 1 clinical developmental requirements for phase 2 clinical efficacy trials. These include, for example, preclinical pharmacology, toxicology, and efficacy studies, bulk supply, GMP manufacturing, and formulation, and regulatory and IND support and phase 1 clinical studies. Suitable types of agents for RAPID may range from single chemical or biological entities to defined complex mixtures with the potential to prevent, reverse, or delay carcinogenesis. For more detailed information, please visit the RAPID web site, http://cancer.gov/rapid. INQUIRIES: Inquiries are encouraged, and the opportunity to clarify issues or answer questions is welcome. Inquires should be sent to: RAPID Program Attn: Emilia A. Richichi, Ph.D. Chemopreventive Agent Development Research Group Division of Cancer Prevention, NCI Executive Plaza North, Room 2117 6130 Executive Blvd., Rockville, MD 20852 (overnight mail) 9000 Rockville Pike, Bethesda, MD 20892 (regular mail) Telephone: (301) 594-1165 Fax: (301) 402-0553 Email: richichi@mail.nih.gov


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