Transforming Processes for NCRR’s General Clinical Research Centers

Notice Number: NOT-RR-06-001

Key Dates
Release Date: October 12, 2005

Issued by
National Center for Research Resources (NCRR), (

Today NIH published an RFA for Institutional Clinical and Translational Science Awards (RFA-RM-06-002). This new Clinical and Translational Science Award (CTSA) program, which NCRR is leading on behalf of the NIH Roadmap for Medical Research, will transform and advance clinical and translational science as a distinct discipline within a definable academic home. Since the RFA will be issued annually, a cademic health centers, including those with GCRCs, can build on their existing resources and transform into this new integrated program over a period of years. Also, a one-time planning grant RFA has been announced to give institutions more time to prepare to apply for a CTSA (RFA-RM-06-001). The CTSA program will build on existing programs by reconfiguring, and adding to, certain NIH awards (NCRR GCRC [M01], K12, K30, and Roadmap T32 and K12) held by the applicant institution and its affiliates.

As part of this process, NCRR will modify procedures for GCRCs as follows:

Institutions with GCRCs that are applying for a CTSA should be aware of the following:

NCRR anticipates that the competitive process that will transform GCRC (M01) grants to CTSAs will be complete by September 30, 2010. NCRR will work flexibly on a case-by-case basis with GCRCs during this transition period to give them time to plan and apply for a CTSA award.


Anthony R. Hayward, M.D., Ph.D.
Division for Clinical Research Resources
National Center for Research Resources
6701 Democracy Boulevard Room 906 - MSC 4874
Bethesda , MD 20892-4874
Telephone: (301) 435-0790
FAX: (301) 480-3661

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