Key Dates
- December 15, 2023 - Notice of Intent to Publish a Funding Opportunity Announcement for Clinical Sites for the Environmental influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network- 3 (UG1 Clinical Trial Required). See Notice NOT-OD-24-045.
Office of The Director, National Institutes of Health (OD)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Office of Behavioral and Social Sciences Research (OBSSR)
The Environmental influences on Child Health Outcomes (ECHO) Program Office intends to publish a notice of funding opportunity announcement (NOFO), issued by the Office of the Director (OD), National Institutes of Health (NIH), invites applications from entities/institutions in Institutional Development Award (IDeA)-eligible states to participate as the Data Coordinating and Operations Center (DCOC) in the Environmental influences on Child Health Outcomes IDeA States Pediatric Clinical Trials Network (ECHO ISPCTN).
There will also be a companion NOFO that will solicit applications for ECHO ISPCTN Clinical Sites (see Notice NOT-OD-24-045). The ECHO ISPCTN DCOC and Clinical Sites together will form the ECHO ISPCTN. The ECHO ISPCTN is the intervention component of the ECHO Program and supports its overall mission to enhance the health of children for generations to come.
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.
The NOFO is expected to be published in January 2024 with an expected application due date in April 2024.
This NOFO will utilize the U24 activity code. Details of the planned NOFO are provided below.
The DCOC award budget will fund approximately five multicenter pediatric clinical trials with each trial related to prevention or treatment of one or more of ECHO’s five outcome areas of interest: pre-, peri-, and postnatal outcomes; upper and lower airways; obesity; neurodevelopment; and positive health. Overall, the five trials should address at least two of the five areas.
The DCOC will support the ECHO ISPCTN Clinical Sites to
- Develop, conduct, and disseminate findings from multicenter clinical trials research, assuring the participation of children living in rural or underserved communities in IDeA states
- Build pediatric clinical trial research capacity in IDeA states funded by the ECHO ISPCTN
- Engage interested parties such as community members, nonprofit organizations, and professional societies to enhance ECHO ISPCTN clinical trial impact, transferability, rigor, and feasibility
Funding Information
A sum of $8,000,000 as total cost has been set aside for funding DCOC in FY 2025.
One award in FY 2025.
$1,750,000 per year in direct costs for the Core Infrastructure Costs for the DCOC, and $3,500,000 per year in direct costs for Protocol-specific Costs for distribution to the ECHO ISPCTN Clinical Sites as capitation fees to conduct clinical trials.
93.310
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization
Eligible Agencies of the Federal Government
Other important eligibility criteria: Only institutions or organizations in the following IDeA states/commonwealth are eligible to respond to this NOFO: these include:
- Alaska, Arkansas, Delaware, Hawaii, Idaho, Kansas, Kentucky, Louisiana, Maine, Mississippi, Montana, Nebraska, Nevada, New Hampshire, New Mexico, North Dakota, Oklahoma, Puerto Rico, Rhode Island, South Carolina, South Dakota, Vermont, West Virginia, and Wyoming.
The NIH ECHO Program Office anticipates the NOFO will encourage each applicant organization to submit only one application.
Applications are not being solicited at this time.
Inquiries
Please direct all inquiries to:
Tonse N.K. Raju, MD
Program Officer
Environmental influences on Child Health Outcomes (ECHO)
Office of the Director, National Institutes of Health
Three White Flint North, Room 03D17
11601 Landsdown Street
North Bethesda, MD 20852
Mobile: 202-302-3984
ECHO Phone: 301-435-5236
[email protected]
and Human Services (HHS)
