Notice of LIMITED COMPETITION - REQUEST FOR A  RENEWAL  APPLICATION: National Swine Resource and Research Center


Notice Number:  NOT-OD-12-119

Key Dates

Release Date:  June 28, 2012

Issued by

Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs (ORIP)

Purpose

The Office of Research Infrastructure Programs (ORIP), Division of Program Coordination, Planning, and Strategic Initiatives, OD is announcing a limited competition, under the P40 program (http://grants.nih.gov/grants/guide/pa-files/PAR-11-001.html ), for a renewal application for the National Swine Resource and Research Center (NSRRC).  The NSRRC, currently funded as a cooperative agreement (U42), serves as a central resource for the creation of genetically modified swine, and as a source of information and training related to the use of these animals in biomedical research and is expected to continue as a unique ongoing resource at its current scope. 

Optimally the NSRRC should maintain its present structure since any organizational change would require a rebuilding of infrastructure (construction of the Center with state-of-the-art high biosecurity) to ensure that biomedical investigators across a variety of disciplines have access to critically needed swine models.

The awardee is expected to acquire, maintain, preserve, and distribute swine models for studies of human diseases, as well as the cryopreservation, storage, and reconstitution of embryos and germplasm.  The resource center will continue to serve as a central resource for reagents, creation of new genetically modified swine, and information and training related to use of swine models in biomedical research.  In addition, the NSRRC will continue to develop methods for improving health of swine strains by establishing standards and procedures for generating specific-pathogen free and more vigorous swine strains and characterizing diseases endemic to laboratory swine stocks. Furthermore, because the resource is expected to maintain swine strains for xenograft transplantation procedures, it is essential that the center be able to accommodate the specific needs for isolation, growth, preservation, expansion, and distribution of cells, tissues and organs from these animals.

Inquiries

Please direct all inquiries to:

Michael Chang, Ph.D.
Division of Comparative Medicine
Office of Research Infrastructure Programs, OD, NIH
6701 Democracy Boulevard
Room 942, MSC4874
Bethesda, MD 20892-4874
Phone: 301-435-0744
FAX: 301-480-3819
Email: changmic@mail.nih.gov


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