Notice of Change to Key Dates for PAR-25-049: NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
Notice Number:
NOT-NS-26-027

Key Dates

Release Date:

March 3, 2026

Related Announcements

  • November 7, 2024 - NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required). See NOFO PAR-25-049.

Issued by

National Institute of Neurological Disorders and Stroke (NINDS)

Purpose

The purpose of this notice is to inform potential applicants of a change in the key dates for notice of funding opportunity (NOFO)  PAR-25-049, NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required). Specifically, an additional receipt date of June 6, 2026 has been added to this NOFO for new applications, and an additional receipt date of July 08, 2026 has been added to this NOFO for renewal applications. Accordingly,  this NOFO now expires on July 9, 2026. 

The following section of PAR-25-049 has been modified.

Part 1. Overview Information

Key Dates

Currently reads:

Application Due Dates

Review and Award Cycles

NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
February 07, 2025March 07, 2025Not ApplicableJuly 2025October 2025December 2025
June 06, 2025July 08, 2025Not ApplicableNovember 2025January 2026April 2026
October 07, 2025November 07, 2025Not ApplicableMarch 2026May 2026July 2026
February 06, 2026March 06, 2026Not ApplicableJuly 2026October 2026December 2026

All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Expiration Date: March 07, 2026
 

Modified to Read (key changes are adding additional line in table of receipt dates and updating expiration date in bold italics)

Application Due Dates

Review and Award Cycles

NewRenewal / Resubmission / Revision (as allowed)AIDS - New/Renewal/Resubmission/Revision, as allowedScientific Merit ReviewAdvisory Council ReviewEarliest Start Date
February 07, 2025March 07, 2025Not ApplicableJuly 2025October 2025December 2025
June 06, 2025July 08, 2025Not ApplicableNovember 2025January 2026April 2026
October 07, 2025November 07, 2025Not ApplicableMarch 2026May 2026July 2026
February 06, 2026March 06, 2026Not ApplicableJuly 2026October 2026December 2026
June 06, 2026July 08, 2026Not ApplicableNovember 2026January 2027April 2027

All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Expiration Date: July 09, 2026

Inquiries

Please direct all inquiries to:


Office of Emergency Care Research
National Institute of Neurological Disorders & Stroke (NINDS)
Email: [email protected]