NOT-NS-19-035: Notice of Change to IC and NIH Office of Interest Areas and Specific Requirements for RFA-NS-19-009 "Promoting Research on Music and Health: Fundamentals and Applications (R21 Clinical Trial Optional)"

Notice of Change to IC and NIH Office of Interest Areas and Specific Requirements for RFA-NS-19-009 "Promoting Research on Music and Health: Fundamentals and Applications (R21 Clinical Trial Optional)"

Notice Number: NOT-NS-19-035

Key Dates
Release Date : February 05, 2019

Related Announcements
RFA-NS-19-009

Issued by
National Institute of Neurological Disorders and Stroke (NINDS)
National Eye Institute (NEI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Purpose

The purpose of this notice is to inform interested applicants of a change to IC and NIH Office of Interest Areas and Specific Requirements for RFA-NS-19-009 "Promoting Research on Music and Health: Fundamentals and Applications (R21 Clinical Trial Optional)". The IC and NIH Office of Interest Areas and Specific Requirements have been modified to include information that was erroneously omitted. IC-specific Areas of Interest and Specific Requirements have been added for the National Eye Institute (NEI), the National Institute on Alcohol Abuse (NIAAA) and the National Institute on Aging (NIA).

Currently Reads:

Part 2. Full Text Announcement

Section I. Funding Opportunity Description

IC and NIH Office Interest Areas and Specific Requirements

Understanding the basic science of music and exploring its potential to enhance health and treat disease is relevant to the mission of the NIH Institutes participating in this FOA. Below is a list of areas that are of particular interest to participating ICs:

NCCIH: The National Center for Complementary and Integrative Health (NCCIH) is broadly interested in supporting research aimed at understanding the mechanisms by which music and music interventions impact symptom management in high-priority topics such as pain, stress-related disorders, sleep disorders. NICCH is also interested in how music and music intervention could be used to address opioid misuse and enhancement of emotional well-being. In addition to basic animal model work, NCCIH supports mechanistic clinical trials under this FOA. However, NCCIH will not support grant applications proposing efficacy or effectiveness research with primary clinical outcomes under this FOA. Investigators who are ready to propose a fully powered efficacy or effectiveness clinical trials can apply to PAR-18-662 with a companion application to PAR-18-663 for an independent data coordinating center. Investigators are strongly encouraged to contact program staff to discuss their aims prior to submission.

Modified to Read:

Part 2. Full Text Announcement

Section I. Funding Opportunity Description

IC and NIH Office Interest Areas and Specific Requirements

NEI: The National Eye Institute (NEI) supports research that addresses blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind. Under this FOA, NEI will accept applications that propose to examine how music affects the fundamental mechanisms of visual function or loss of vision, which may inform development of music-based interventions for the visually impaired. Topics of interest include, but are not restricted to, the role of music in neural reorganization and plasticity in the visually impaired; the impact of music on sensory substitution, navigation/mobility, and functional strategies in the visually impaired; and music integration in low vision rehabilitation.

NIAAA: The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is interested in supporting research within the mission of NIAAA. Example research areas of interest to NIAAA include 1) How does music modulate negative emotion states associated with alcohol dependence and withdrawal? What are the biological and neurological underpinnings of the modulation? 2) How does alcohol exposure across the life span, during early development, adolescent stage, adult, and aging, impact music processing? 3) Can music facilitate cognitive recovery following heavy chronic alcohol use, and what are the underlying neurocircuit mechanisms? 4) How does music impact recovery from alcohol use disorders? Which types of music might promote sustained abstinence?

NIA: The National Institute on Aging (NIA) is interested in research to increase our basic understanding of how music affects the brain, body and behavior with aging. Of specific interest is research to investigate the neural pathways and circuits involved in music processing and how these may be altered in aging, the mechanisms by which the experience of music may affect brain structure and function in aging and the potential for music to induce neural and behavioral plasticity in aging and the underlying mechanisms. NIA is also interested in behavioral intervention development, in accordance with the NIH Stage Model (please see https://www.nia.nih.gov/research/dbsr/stage-model-behavioral-intervention-development) that capitalizes on and integrates basic research on music to inform the development of efficacious interventions for individuals as they age. The purpose of the interventions to be developed may be, for example, to promote health and well-being, promote behaviors associated with health and well-being (e.g., exercise), cope with stress (e.g., dementia caregivers), improve the emotional/behavioral status of care providers of individuals with dementia, help individuals deal with age-related disorders (e.g., Parkinson s), help older individuals with declining memory improve their memory. Applications to NIA proposing behavioral intervention development research are encouraged to use NIH Science of Behavior Change experimental medicine methodology (for more information about the SOBC program, please see: https://commonfund.nih.gov/behaviorchange).

All other aspects of this FOA remain the same.

Inquiries

Please direct all inquiries to:

Robert Riddle, Ph.D.
National Institute of Neurological Disorders and Stroke (NINDS)
Telephone:301-496-5745
Email: riddler@ninds.nih.gov