Plan To Include All Parkinson's Disease Biomarkers Projects in the NINDS Parkinson's Disease Biomarkers Program (PDBP)

Notice Number: NOT-NS-13-020

Key Dates

Release Date:  March 20, 2013

Issued by

National Institute of Neurological Disorders and Stroke (NINDS)


The creation of the NINDS Parkinson’s Disease Biomarkers Program (PDBP) has resulted in an opportunity for a common platform for exchanging data, protocols, and biospecimens for Parkinson’s Disease (PD) Biomarkers Research. NINDS expects that projects studying Parkinson’s Disease biomarkers will utilize the PDBP Data Management Resource (DMR), which NINDS has created in order to accelerate progress in this field.


The overall goal of the NINDS Parkinson’s Disease Biomarkers Program (PDBP)  is to allow the rapid identification and development of potential biomarkers to improve the efficiency and outcome of Phase II or III clinical trials of neuroprotective agents in Parkinson’s Disease.  In order to accomplish this goal, it is essential that there be a concerted effort to collect biospecimens, imaging, and clinical data using standardized approaches.  Furthermore, a collaborative environment will be essential for success of this program; therefore sharing standards and policies have been established.

Brief Summary of PDBP Policies

Details regarding PDBP structure and policies can be found at  A brief selection of policy highlights includes:

Selected NINDS grantees will be invited to attend two meetings per year to discuss PDBP progress and policy, and be included in the PDBP Steering Committee, as a part of the consortium. Plans for the costs of attending up to two PDBP organizational meetings per year should be included in the application budget.


This policy will apply to all NINDS projects in PD Biomarkers research (including R01, U01, P50, P01, and other mechanisms). Because extensive programmatic input and coordination are required for NINDS PDBP projects, successful applications may be converted to cooperative agreements (U mechanism).

Applicants who are proposing PD biomarker studies are urged to contact their NINDS program director prior to submission in order to allow ample planning for coordination with the PDBP and with PDBP policies.


Please direct all inquiries to:

Katrina Gwinn, MD
Program Director
Division of Extramural Research
National Institute of Neurological Disorders and Stroke
Telephone: 301-496-5745

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