Notice of Intent to Publish a Request for Applications for a Parkinson Disease Biomarkers Identification Network Coordinating Center (U01)

Notice Number: NOT-NS-10-024

Key Dates
Release Date:  August 3, 2010

Issued by
National Institute of Neurological Disorders and Stroke (NINDS), (


The National Institute of Neurological Disorders and Stroke (NINDS) intends to issue a Request for Applications (RFA) for grant applications in support of a data coordinating center (DCC) and clinical coordinating center (CCC) focused initially on the discovery and validation of biological markers of Parkinson’s disease (PD).  The NINDS convened a conference in May of 2010 to discuss the current state of biomarker development in PD and how development and validation of biomarkers could most effectively be fostered.  Based on the insights and recommendations provided at the conference, this effort is being developed as part of the NINDS response to the critical need for biomarker development in PD.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The RFA is expected to be published in the Fall of 2010 with a receipt date in early 2011.  This RFA will utilize the U01 Cooperative Agreement Research Project funding mechanism.  

This Notice encourages investigators with expertise in Parkinson’s Disease to begin to consider applying for this new RFA.  Additional expertise in subject recruitment, clinical site identification, coordination of standardized biospecimen collection, and operation of a public database for standardized data collection and dissemination is also highly desirable.  One or more separate FOAs may be published to invite discovery validation and other biomarker projects to be performed within the network.



Interested parties may contact:

Katrina Gwinn MD
National Institute of Neurological Disorders and Stroke
National Institutes of Health
6001 Executive Blvd Room 2143
Bethesda, MD  20892
Express/Courier: Rockville, MD  20852
Phone: (301) 496-5745
Fax: (301) 401-5301

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