Release Date:  August 30, 2001

NOTICE:  NOT-NS-01-013

National Institute of Neurological Disorders and Stroke

The National Institute of Neurological Disorders and Stroke (NINDS) announces 
an administrative supplement program to enhance infrastructure of neuro-AIDS 
research projects.  The program is intended to further research on neuro-AIDS 
for ongoing, peer-reviewed neuro-AIDS research projects.  Principal 
Investigators (PIs) with Research Project (R01), exploratory/development 
(R21), FIRST (R29), Program Project (P01), and Specialized Center (P50, U54) 
grants and Collaborative Neurological Science Awards (S11) funded by NINDS 
are eligible to apply.  To be eligible, projects must have a Project Period 
End Date of August 31, 2002 or later (a no cost extension beyond that date 
does not confer eligibility).  In addition, grants must not have received an 
administrative supplement within the past 12 months nor received an 
infrastructure supplement under the program announced in NOT-98-166.  We have 
mailed this announcement directly to those we believe are eligible for this 
program.  If you feel that you meet the eligibility requirements but were not 
contacted directly, please contact one of the program officials listed at the 
end of this announcement.

The principal focus of this announcement is to support the purchase of 
equipment that could not be purchased because of previous budgetary 
constraints, although requests for other non-recurring infrastructure support 
that will enhance the ongoing NINDS-funded neuro-AIDS research will be 

Evidence should be presented that the supplement will significantly enhance 
the pursuit of the existing Specific Aims of the participating research 
project, without constituting an expansion of scope.  Descriptions should be 
concise, but sufficiently detailed to make clear how the supplemental funds 
will enhance the ongoing research project.

How to apply:  Submission of requests should be made electronically.  Send an 
email message to  with the PI's name (last name, 
first name) and grant number (e.g., R01NS01234-05) on the Subject line.  
Include the following sections in an attached file in MSWord format:

1) A cover letter citing this NOTICE and requesting an administrative 
supplement, including the PI name, grant number and title, amount requested, 
name and title of the institutional official, and phone, email, and address 
information for the PI and institutional official.  For P01s, P50s, and U54s, 
the named PI must submit the request for a supplement.
2) A description of the project (up to 2 pages), including an Abstract, a 
Description of the experiments which will be enhanced by the infrastructure 
supplement and their relationship to the original project Specific Aims 
including a discussion of the Impact that the supplement will have on the 
overall project, and a Budget with justification.
3) A list of other support for the PI and key personnel.
4) Specific Aims from the original grant.

PIs should not submit a request electronically until the institutional 
business office has reviewed and approved the request. Applicants unable to 
submit an electronic application should submit a complete written application 
addressed to Dr. Kozlowski postmarked no later than September 6, 2001.

Following electronic submission, an original cover letter signed by the PI 
and countersigned by an authorized institutional official, which is required 
for issuance of an award, must be sent by mail or fax to the NINDS program 
staff contact listed at the end of this notice.  Please submit only once, 
either via mail or by fax.

Budget information:  Supplements will be awarded as TOTAL COSTS in increments 
of $25,000.  For R01s, R21s, R29s, and S11s, the maximum request is $50,000.  
For P01s, P50s, and U54s, the maximum is $100,000.  Applicants should provide 
a budget justification that details the budget items requested. 

Review procedure:  Applications will be reviewed administratively.

Review criteria:
o The relevance of the supplement to the Specific Aims of the parent grant
o The relevance to program priorities of the institute

Receipt date:  September 6, 2001 (11:59 P.M. for electronic submissions)
Award date: September 30, 2001

A website with FAQs about the program has been provided at

Direct inquiries to:

Piotr B. Kozlowski M.D., Ph.D.
National Institute of Neurological Disorders and Stroke
6001 Executive Boulevard, NSC-2118
Bethesda MD  20892-9521
Rockville, MD  20852 (Courier Service only)
Tel:  301-496-1431
Fax:  301-480-2424

David J. Eckstein, Ph.D.
National Institute of Neurological Disorders and Stroke
6001 Executive Boulevard, NSC-2117
Bethesda, MD 20892-9521
Rockville, MD 20852 (Courier Service only)
Tel:  301-496-1431
Fax:  301-480-2424

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