NINDS ADMINISTRATIVE SUPPLEMENTS FOR RESEARCH ON PARKINSON"S DISEASE Release Date: November 16, 2000 NOTICE: NS-01-002 National Institute of Neurological Disorders and Stroke The National Institute of Neurological Disorders and Stroke (NINDS) announces an administrative supplement program of up to $3 million in FY2001 to foster additional research on Parkinson"s Disease (PD) across a wide variety of scientific disciplines, and to allow investigators not currently working in PD to join the field. This supplemental funding initiative is issued in response to recommendations in the Parkinson"s Disease Research Agenda, available on the website: http://www.ninds.nih.gov/about_ninds/plans/nihparkinsons_agenda.htm calling for innovative funding mechanisms. This program is intended to facilitate research within ongoing, peer-reviewed projects that have Specific Aims on PD, or Specific Aims within other areas that may translate to PD (see bullets below). These one-time supplements are intended to help grantees develop preliminary data for new R21"s or R01"s. Principal Investigators (PIs) with Research Project (R01), Exploratory/Developmental (R21), FIRST (R29), Phase II SBIR (R44), Program Project (P01), and Specialized Center (P50 or U54) grants are eligible to apply. To be eligible, projects must have a Project Period End Date of April 30, 2002, or later (a no-cost extension beyond that date does not confer eligibility). Evidence should be presented that the results of the supplemental assistance will enhance the pursuit of Specific Aims of the research project, and be focused on Parkinson"s Disease, without constituting an expansion of scope. Supplements are one-time awards and will not extend to subsequent years. Specific examples of supplemental requests that may be considered include, but are not limited to: o Requests involving the basic cellular and molecular biology or basic pathophysiology of PD within existing PD grants. o Analysis of animal models, developed through existing grants on other disorders, for potential use in PD. Models may include invertebrates. o Requests within existing grants on the development of biomarkers or genetic tools in neurodegnerative diseases to include PD. How to Apply: Submission of requests should be made electronically. Send an email message to: PDsupplements@ninds.nih.gov with the PI"s name (last, first) and grant number on the subject line. Include the following items in an attached file in MSWord, WordPerfect, or PDF format. 1) A cover page citing this NOTICE and requesting an administrative supplement. Include the PI name, grant number and title, amount requested, name and title of the institutional official, and phone, email, and address information for the PI and institutional official. For P01s, P50s, and U54s the overall project PI must submit the request for a supplement. 2) A letter (5-page limit) describing the project, including an abstract, a description of the proposed experiments and their relationship to the original project Specific Aims, a discussion of the significance of the results to PD, and a budget with justifications. 3) Biographical sketch of the PI. 4) Specific Aims of the original grant. 5) Documentation of co-funding, if appropriate. In addition, an original cover page signed by the PI and countersigned by the institutional official should be submitted by mail. This is required for the issuance of an award, and should be sent to the NINDS staff contact for application issues, Dr. Carlos Pena, listed at the end of this notice. The cover page is not the cover page of the original grant, but is specific for this request. It should be formatted as a memo or letter and provide the information listed above. PIs should not submit a request electronically until the institutional business office has reviewed and approved the request. A separate copy is not needed for Grants Management. Applicants unable to submit electronic applications should submit a complete written application addressed to the same NINDS contact. Budget Information: Supplements will be awarded as TOTAL COSTS, and are one-time awards. Any Facilities and Administrative (indirect) costs should be included in the modular request, and may not be added to it. For R01s, R21s, R29s, and R44s the maximum request is $50,000. For P01s, P50s, and U54s the maximum is $100,000. Although the awarded budgets will be modular, applicants should provide budget justification that details the budget items requested, including Facilities and Administrative (F&A) costs. Review Procedures: Requests will be reviewed administratively. Review criteria will include the scientific significance to PD research, and relevance to program priorities of the institute. Post-Award Requirements: A short, 1-page progress report addressing the results of the supplement will be required as an addition to the subsequent progress report of the parent grant. Receipt Date: February 7, 2001 Earliest Award Date: May 1, 2001 Inquiries: A website with FAQ"s about the program has been provided at: http://www.ninds.nih.gov/funding/pdsupplements.htm Direct inquiries regarding programmatic issues to: Dr. Diane D. Murphy Program Director, Neurodegeneration Group National Institute of Neurological Disorders and Stroke 6001 Executive Blvd. NSC Rm. 2223 Bethesda, MD 20892 Tel: (301) 496-5680 Fax: (301) 480-1080 Email: dm152o@nih.gov Direct inquiries regarding application issues to: Dr. Carlos Pena Program Analyst, Neurodegeneration Group National Institute of Neurological Disorders and Stroke 6001 Executive Blvd. NSC Rm. 2228 6001 Executive Blvd. NSC Rm. 2223 Bethesda, MD 20892 Tel: (301) 496-5680 Fax: (301) 480-1080 Email: penac@ninds.nih.gov Direct inquiries regarding fiscal matters to: Dianna Jessee Grants Management Branch National Institute of Neurological Disorders and Stroke 6001 Executive Blvd., NSC 3290 Bethesda, Maryland 20892 Tel: 301-496-9231 Fax: 301-402-0219 Email: dj35j@nih.gov
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