NINDS ADMINISTRATIVE SUPPLEMENTS FOR DNA MICROARRAY ANALYSIS Release Date: April 24, 2000 NOTICE: NS-00-007 National Institute of Neurological Disorders and Stroke The National Institute of Neurological Disorders and Stroke (NINDS) announces an administrative supplement program of up to $2.5 million in Fiscal Year 2000 to facilitate access to DNA microarray analyses for NINDS-funded research projects. This administrative supplement program is issued in response to recommendations from the NINDS Strategic Plan (see http://www.ninds.nih.gov/about_ninds/plans/strategic_plan.htm). The program is intended to facilitate access to DNA microarray analysis for ongoing, peer-reviewed projects that have Specific Aims for which microarray analysis will provide clearly relevant data within the scope of the approved project. Principal Investigators (PIs) with Research Project (R01), Program Project (P01), and Research Center (P50) grants funded by NINDS are eligible to apply. To be eligible, projects must be funded in Fiscal Year 2000 and have at least one additional year of funding remaining. Evidence should be presented that the results of the supplemental assistance will significantly enhance the pursuit of Specific Aims of the participating research project, without constituting an expansion of scope. Descriptions should be concise, but sufficiently detailed to make clear the research plan and the relationship of the results of the proposed microarray experiments to the goals of the original project. The principal focus of this announcement is on the use and analysis of arrays. This includes microarrays, reagents, scanners, and data analysis. The purchase of microarray services from commercial vendors or from institutional facilities is acceptable. Requests for salary may be included, in proportion to time directly devoted to the supplemental project. The program, however, is not intended to support the establishment of array-making facilities. Requests for computers and software will be considered only if they are solely for use in microarray analysis. How to apply: Submission of requests should be made electronically. Send an email message to microarrays@ninds.nih.gov with the PI"s name (last name, first name) and grant number (eg., R01NS01234-05) on the Subject line. Include the following sections in an attached file in MSWord or WordPerfect format: 1) A cover page citing this NOTICE and requesting an administrative supplement, including the PI name, grant number and title, amount requested, name and title of the institutional official, and phone, email, and address information for the PI and institutional official. For P01s and P50s, the named PI must submit the request for a supplement. 2) A letter (5-page limit) describing the project, including an Abstract, a Description of the proposed experiments and their relationship to the original project Specific Aims, a discussion of the Significance of the results, and a Budget with justifications and plans for sharing and release of data. 3) Biographical Sketch of the PI. 4) Specific Aims from the original grant. In addition, an original cover page signed by the PI and countersigned by an authorized institutional official, which is required for issuance of an award, should be sent by mail or fax to the NINDS program staff contact listed at the end of this notice. Applicants unable to submit an electronic application should submit a complete written application addressed to the same NINDS staff contact. Budget information: Supplements will be awarded as TOTAL COSTS in modular amounts of $25,000. Facilities and Administrative Costs (F&A) should be included in the modular request. For R01s, the maximum request is $50,000. For P01s and P50s, the maximum is $100,000. Although the awarded budgets will be modular, applicants should provide a budget justification that details the budget items requested, including F&A. If the planned microarray experiments will not be fully supported by the supplemental funds from NINDS, the sources and amounts of additional funds should be specified. Review procedure: Applications will be reviewed administratively. Review criteria: o The scientific significance of the proposed study o The relevance of the supplemental plan to the Specific Aims of the parent grant o The appropriateness of the experimental approach and data analysis o The relevance to program priorities of the institute o The impact of the results for other areas in neuroscience Data sharing: The review will also consider plans for sharing the data that are obtained from the supplemental research. Recipients of administrative supplements are encouraged to share data on the National Center for Biotechnology Information Gene Expression Omnibus (http://www.ncbi.nlm.nih.gov/geo/). Receipt date: July 3, 2000 Award date: September 29, 2000 Direct inquiries regarding programmatic issues to: Thomas Miller, Ph.D. Technology Development National Institute of Neurological Disorders and Stroke 6001 Executive Boulevard, NSC-2139 Bethesda MD 20892 Tel: 301-496-1779 Fax: 301-402-1501 Email: tm208y@nih.gov Direct inquiries regarding fiscal matters to: Joellen M. Harper Chief, Grants Management Branch National Institute of Neurological Disorders and Stroke 6001 Executive Blvd., NSC-3258 Bethesda, Maryland 20892 Tel: 301-496-9231 Fax: 301-402-0219 Email: jh41m@nih.gov
Weekly TOC for this Announcement
NIH Funding Opportunities and Notices
Office of Extramural Research (OER) |
National Institutes of Health (NIH) 9000 Rockville Pike Bethesda, Maryland 20892 |
Department of Health and Human Services (HHS) |
||||||||