Release Date:  January 9, 2002

NOTICE:  NOT-HS-02-002

RECEIPT DATE:  March 28, 2002

Agency for Healthcare Research and Quality

This notice informs the research community that the Agency for Healthcare 
Research and Quality (AHRQ) will be requesting competitive renewal 
applications from the four Centers for Education and Research on Therapeutics 
(CERTs) for which it provided initial funding in Fiscal Year 1999.

The CERTs program was established with the NIH Guide release of RFA-HS-99-004 
on January 27, 1999, and was incorporated into the AHRQ Reauthorization Act 
of 1999 (P.L. 106-129).  The mission of the CERTs program is to provide 
objective scientific information on the safe and effective use of 
therapeutics, defined as drugs, devices, and biologics.  The purpose of the 
competitive renewals is to provide funds for existing centers to build on 
work in progress and to expand their work to: a) address existing gaps within 
the overall CERTs program including pharmacoeconomics and cost effectiveness 
analyses, and b) develop additional projects within the overarching Center 
theme that complement current AHRQ research priorities and response to the 
needs of programs of the Department of Health and Human Services.  The CERTs 
program is mandated by Congress.  Because the existing CERTs recipients 
possess the infrastructure, leadership, organization, and multidisciplinary 
research objectives to enable them to build on the existing work to address 
existing gaps and to develop additional projects, and because continuity in 
the research is necessary, this will be a limited competition.  In addition, 
ongoing evaluations of the CERTs demonstration activities require that a 
longer period of funding be in place for the current awardees in order to 
determine the appropriate structure for the permanent Agency program.

Questions regarding this Notice can be submitted to:  Lynn Bosco, MD MPH, 
AHRQ, Center for Outcomes and Effectiveness Research, 6010 Executive Blvd., 
Suite 300, Rockville MD 20852, Phone (301) 594-2416, Fax: (301) 594-3211, 
Email:  Lbosco@AHRQ.GOV.

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